Cheap Flights from Myrtle Beach, SC to Chicago, IL from $48
Return flight: Chicago – Myrtle Beach
On Cheapflightsplus.com you will find 7 direct and 369 connecting flights from Myrtle Beach to Chicago. You can compare airfare deals from 4 airlines and multiple travel sites from $48, book and save on cheap plane tickets and last minute offers. Also check out MYR-CHI flight schedule to find best flight time, convenient departure and arrival airports.
Find One-Way and Round-Trip Myrtle Beach to Chicago Flight Deals
To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights».
To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight.
Cheapest flights in November: $48 (one-way), $82 (round-trip).
Direct flights
Check prices for return flight
Best Flights from Myrtle Beach to Chicago Today
Take a look at the list of non stop flights and flights with layovers from Myrtle Beach to Chicago with the lowest price of $48. The fastest direct flight takes 2h 24m and the fastest connecting – 4h 50m.
| Price | Departure | Arrival | Flight Duration | Airline | Flight |
|---|---|---|---|---|---|
| from $48 | 15:16 Myrtle Beach AFB | 16:41 Chicago O'Hare International | 2h 25m | Spirit Airlines | NK1815 |
| from $48 | 17:54 Myrtle Beach AFB | 19:19 Chicago O'Hare International | 2h 25m | Spirit Airlines | NK3190 |
| from $79 | 13:53 Myrtle Beach AFB | 15:17 Chicago O'Hare International | 2h 24m | Spirit Airlines | NK3033 |
| from $106 | 16:45 Myrtle Beach AFB | 18:22 Chicago O'Hare International | 2h 37m | United Airlines | UA5335 |
| from $107 | 16:50 Myrtle Beach AFB | 18:20 Chicago O'Hare International | 2h 30m | United Airlines | UA1580 |
| from $155 | 16:45 Myrtle Beach AFB | 18:14 Chicago O'Hare International | 2h 29m | United Airlines | UA444 |
| from $74 | 05:00 Myrtle Beach AFB | 09:55 Chicago O'Hare International | 5h 55m layover 0h 48m - Miami | Spirit Airlines | NK3646 NK2 |
| from $74 | 08:34 Myrtle Beach AFB | 14:41 Chicago O'Hare International | 7h 7m layover 2h 27m - Newark | Spirit Airlines | NK1003 NK1183 |
| from $81 | 06:10 Myrtle Beach AFB | 15:31 Chicago O'Hare International | 10h 21m layover 5h 51m - Orlando | Spirit Airlines | NK1289 NK1369 |
| from $81 | 06:10 Myrtle Beach AFB | 17:17 Chicago O'Hare International | 12h 7m layover 7h 36m - Orlando | Spirit Airlines | NK1289 NK1114 |
| from $104 | 19:13 Myrtle Beach AFB | 20:00+1 день Chicago O'Hare International | 25h 47m layover 21h 20m - New York | Spirit Airlines | NK1809 NK1179 |
| from $111 | 08:34 Myrtle Beach AFB | 20:00 Chicago O'Hare International | 12h 26m layover 8h 0m - New York | Spirit Airlines | NK1003 NK1179 |
| from $114 | 10:33 Myrtle Beach AFB | 23:10 Chicago O'Hare International | 13h 37m layover 9h 10m - Newark | Spirit Airlines | NK3020 NK329 |
| from $120 | 14:52 Myrtle Beach AFB | 23:10 Chicago O'Hare International | 9h 18m layover 4h 53m - Newark | Spirit Airlines | NK2965 NK329 |
| from $115 | 14:31 Myrtle Beach AFB | 08:22+1 день Chicago Midway | 18h 51m layover 5h 35m - Belleville 7h 15m - Fort Walton Beach | Allegiant Air | G43112 G43102 G41455 |
| from $115 | 14:31 Myrtle Beach AFB | 13:56+1 день Chicago Midway | 24h 25m layover 3h 39m - Belleville 16h 5m - Knoxville | Allegiant Air | G43112 G41417 G43026 |
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on June 28, 2025
Flight Schedule Myrtle Beach (South Carolina) to Chicago (Illinois)
Full flight schedule will help you in detecting at what time planes fly from Myrtle Beach to Chicago. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
| Departure | Arrival | Flight Details | Flight Duration | Price |
|---|---|---|---|---|
|
11:35 — 13:05
|
11:35 — 13:05
UA752
United Airlines
Myrtle Beach — Chicago
|
2h 30m |
Find flight
from$171 |
|
|
13:53 — 15:17
|
13:53 — 15:17
NK3033
Spirit Airlines
Myrtle Beach — Chicago
|
2h 24m |
Find flight
from$79 |
|
|
15:16 — 16:41
|
15:16 — 16:41
NK1815
Spirit Airlines
Myrtle Beach — Chicago
|
2h 25m |
Find flight
from$48 |
|
|
16:45 — 18:22
|
16:45 — 18:22
UA5335
United Airlines
Myrtle Beach — Chicago
|
2h 37m |
Find flight
from$106 |
|
|
16:45 — 18:14
|
16:45 — 18:14
UA444
United Airlines
Myrtle Beach — Chicago
|
2h 29m |
Find flight
from$155 |
|
|
16:50 — 18:20
|
16:50 — 18:20
UA1580
United Airlines
Myrtle Beach — Chicago
|
2h 30m |
Find flight
from$107 |
|
|
17:54 — 19:19
|
17:54 — 19:19
NK3190
Spirit Airlines
Myrtle Beach — Chicago
|
2h 25m |
Find flight
from$48 |
|
|
05:00 — 09:55
|
05:00 — 06:52
NK3646
Spirit Airlines
Myrtle Beach — Miami
48m stop
07:40 — 09:55
NK2
Spirit Airlines
Miami — Chicago
|
5h 55m including layover |
Find flight
from$74 |
|
|
05:00 — 14:34
|
05:00 — 06:52
NK3646
Spirit Airlines
Myrtle Beach — Miami
5h 25m stop
12:17 — 14:34
NK866
Spirit Airlines
Miami — Chicago
|
10h 34m including layover |
Find flight
from$74 |
|
|
06:10 — 15:31
|
06:10 — 07:32
NK1289
Spirit Airlines
Myrtle Beach — Orlando
5h 51m stop
13:23 — 15:31
NK1369
Spirit Airlines
Orlando — Chicago
|
10h 21m including layover |
Find flight
from$81 |
|
|
06:10 — 17:17
|
06:10 — 07:32
NK1289
Spirit Airlines
Myrtle Beach — Orlando
7h 36m stop
15:08 — 17:17
NK1114
Spirit Airlines
Orlando — Chicago
|
12h 7m including layover |
Find flight
from$81 |
|
|
08:34 — 14:41
|
08:34 — 10:30
NK1003
Spirit Airlines
Myrtle Beach — Newark
2h 27m stop
12:57 — 14:41
NK1183
Spirit Airlines
Newark — Chicago
|
7h 7m including layover |
Find flight
from$74 |
|
|
08:34 — 20:00
|
08:34 — 10:30
NK1003
Spirit Airlines
Myrtle Beach — New York
8h stop
18:30 — 20:00
NK1179
Spirit Airlines
New York — Chicago
|
12h 26m including layover |
Find flight
from$111 |
|
|
10:33 — 23:10
|
10:33 — 12:23
NK3020
Spirit Airlines
Myrtle Beach — Newark
9h 10m stop
21:33 — 23:10
NK329
Spirit Airlines
Newark — Chicago
|
13h 37m including layover |
Find flight
from$114 |
|
|
11:28 — 20:23
|
06:00 — 07:28
NK2644
Spirit Airlines
Myrtle Beach — Orlando
5h 22m stop
17:55 — 20:03
NK2541
Spirit Airlines
Orlando — Chicago
|
9h 55m including layover |
Find flight
from$135 |
|
|
11:28 — 18:44
|
06:00 — 07:28
NK2644
Spirit Airlines
Myrtle Beach — Orlando
3h 45m stop
21:25 — 23:29
NK2190
Spirit Airlines
Orlando — Chicago
|
8h 16m including layover |
Find flight
from$141 |
|
|
14:52 — 19:17
|
14:52 — 16:40
NK2965
Spirit Airlines
Myrtle Beach — New York
55m stop
17:35 — 19:17
NK918
Spirit Airlines
New York — Chicago
|
5h 25m including layover |
Find flight
from$78 |
|
|
19:13 — 20:00
+1 day
|
19:13 — 21:10
NK1809
Spirit Airlines
Myrtle Beach — New York
21h 20m stop
18:30 — 20:00
NK1179
Spirit Airlines
New York — Chicago
|
25h 47m including layover |
Find flight
from$104 |
|
|
19:13 — 14:41
+1 day
|
19:13 — 21:10
NK1809
Spirit Airlines
Myrtle Beach — Newark
15h 47m stop
12:57 — 14:41
NK1183
Spirit Airlines
Newark — Chicago
|
20h 28m including layover |
Find flight
from$144 |
|
|
20:30 — 20:00
+1 day
|
20:30 — 22:12
NK1696
Spirit Airlines
Myrtle Beach — New York
20h 18m stop
18:30 — 20:00
NK1179
Spirit Airlines
New York — Chicago
|
24h 30m including layover |
Find flight
from$118 |
|
|
10:33 — 18:43
+1 day
|
10:33 — 12:23
NK3020
Spirit Airlines
Myrtle Beach — Newark
4h 22m stop
16:45 — 19:35
NK1900
Spirit Airlines
Newark — Orlando
20h 58m stop
16:33 — 18:43
NK506
Spirit Airlines
Orlando — Chicago
|
33h 10m including layover |
Find flight
from$117 |
|
|
12:11 — 08:22
+1 day
|
12:09 — 13:34
G4982
Allegiant Air
Myrtle Beach — Lexington
9h 5m stop
22:44 — 23:26
G41481
Allegiant Air
Lexington — Fort Walton Beach
6h 35m stop
06:00 — 08:22
G41455
Allegiant Air
Fort Walton Beach — Chicago
|
21h 11m including layover |
Find flight
from$117 |
|
|
12:37 — 08:55
+1 day
|
12:37 — 13:52
G42598
Allegiant Air
Myrtle Beach — Huntington
6h 4m stop
19:56 — 22:18
G43471
Allegiant Air
Huntington — Miami
8h 22m stop
06:40 — 08:55
NK1986
Spirit Airlines
Miami — Chicago
|
21h 18m including layover |
Find flight
from$125 |
|
|
14:31 — 08:22
+1 day
|
14:31 — 15:27
G43112
Allegiant Air
Myrtle Beach — Belleville
5h 35m stop
21:02 — 22:45
G43102
Allegiant Air
Belleville — Fort Walton Beach
7h 15m stop
06:00 — 08:22
G41455
Allegiant Air
Fort Walton Beach — Chicago
|
18h 51m including layover |
Find flight
from$115 |
|
|
17:07 — 20:00
+1 day
|
17:07 — 17:40
NK1492
Spirit Airlines
Myrtle Beach — Nashville
3h 10m stop
20:50 — 23:59
NK1419
Spirit Airlines
Nashville — New York
18h 31m stop
18:30 — 20:00
NK1179
Spirit Airlines
New York — Chicago
|
27h 53m including layover |
Find flight
from$128 |
|
|
18:04 — 09:55
+1 day
|
18:04 — 19:33
NK137
Spirit Airlines
Myrtle Beach — Orlando
9h 57m stop
05:30 — 06:35
NK195
Spirit Airlines
Orlando — Miami
1h 5m stop
07:40 — 09:55
NK2
Spirit Airlines
Miami — Chicago
|
16h 51m including layover |
Find flight
from$130 |
|
|
18:04 — 13:51
+1 day
|
18:04 — 19:33
NK137
Spirit Airlines
Myrtle Beach — Orlando
10h 42m stop
06:15 — 07:02
NK423
Spirit Airlines
Orlando — New Orleans
4h 15m stop
11:17 — 13:51
NK1834
Spirit Airlines
New Orleans — Chicago
|
20h 47m including layover |
Find flight
from$130 |
|
|
20:34 — 15:33
+1 day
|
20:34 — 22:16
NK2473
Spirit Airlines
Myrtle Beach — Newark
8h 37m stop
06:53 — 08:16
NK2214
Spirit Airlines
Newark — Nashville
5h 14m stop
13:30 — 15:33
NK2028
Spirit Airlines
Nashville — Chicago
|
19h 59m including layover |
Find flight
from$121 |
|
|
21:20 — 17:15
+1 day
|
21:20 — 23:25
NK2475
Spirit Airlines
Myrtle Beach — Detroit
6h 50m stop
06:15 — 07:02
NK2567
Spirit Airlines
Detroit — Minneapolis
8h 34m stop
17:36 — 19:17
SY261
Sun Country Airlines
Minneapolis — Chicago
|
20h 55m including layover |
Find flight
from$141 |
|
*Departure and arrival times - local. Updated on June 28, 2025
Flight Information
Below we will explain in detail what the flights cost on the destination from Myrtle Beach to Chicago depends on and how to choose the most interesting flight option for you.
Distance between Myrtle Beach and Chicago is 1189 miles. Time difference between the cities is 1h. Airplanes depart 05:00 to 21:55 from 2 Myrtle Beach airports and arrive 05:00 to 21:55 to 7 Chicago airports. Average flight time is 2h 29m.
- The fastest flight 2h 24m
- Average flight time 2h 29m
- The earliest flight 05:00
- The latest flight 21:55
- Distance 739 ml
The cheapest months to travel to Chicago are july (from 65 $), august (from 65 $), october (from 104 $).
The most expensive months are may (from 193 $), june (from 110 $), september (from 108 $).
What is the lowest airfare Myrtle Beach to Chicago?
The cheapest plane ticket found by our users is $48. This airfare is for economy class on one-way NK1815 flight by Spirit Airlines for July 24, 2025 which leaves AFB in Myrtle Beach at 15:16 am and arrives at Chicago O'Hare International at 16:41.
Economy class
$48
Business class
?
First class
?
Popular Airlines on the Route
The flight Myrtle Beach — Chicago is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Mexicana - 7 departures per week at the price of from $ 190 . And the most expensive tickets are offered by United Airlines airline - from $ 1042.
Direct flights
There are 7 nonstop flights on the route. The fastest direct flight is NK3033 by Spirit Airlines takes 2h 24m and the cheapest is NK1815 by Spirit Airlines for $48.
- UA - United Airlinesfrom $106Find
- NK - Spirit Airlinesfrom $48Find
See more direct flights
Connecting Flights
There are 369 flights with layovers on the route. The fastest connecting flight is UA4334 by United Airlines takes 4h 50m and the cheapest is NK1815 by Spirit Airlines for $74.
- MX - Mexicanafrom $190Find
- UA - United Airlinesfrom $162Find
- NK - Spirit Airlinesfrom $74Find
- G4 - Allegiant Airfrom $115Find
See more connecting flights
Airports
You can fly from Myrtle Beach to Chicago from 2 airports (AFB, Grand Strand Airport).
Myrtle Beach airports
- AFB-MYRfrom $48Find
- Grand Strand Airport-CREFind
Chicago airports
- O'Hare International-ORDFind
- Midway-MDWFind
- Dupage County-DPAFind
- Chicago FSS-CHIFind
- Merrill C Meigs (closed)-CGXFind
- Pal-Waukee-PWKFind
- Chicago NAS-NOHFind
Airplanes
There are flights to Chicago from Myrtle Beach by 4 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Myrtle Beach
You may also consider searching for discounted plane tickets to some other popular places from Myrtle Beach within United States.
- from $66Find
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Top International Destinations from Myrtle Beach
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
- from $57Find
How to book a plane ticket yourself?
- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
- Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
- Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
- Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
- That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
To find a plane ticket, please select dates.