Cheap Flights from Myrtle Beach, SC to Chicago, IL from $40
Return flight: Chicago – Myrtle Beach
On Cheapflightsplus.com you will find 5 direct and 233 connecting flights from Myrtle Beach to Chicago. You can compare airfare deals from 6 airlines and multiple travel sites from $40, book and save on cheap plane tickets and last minute offers. Also check out MYR-CHI flight schedule to find best flight time, convenient departure and arrival airports.
Find One-Way and Round-Trip Myrtle Beach to Chicago Flight Deals
To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights».
To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight.
Cheapest flights in November: $40 (one-way), $69 (round-trip).
Direct flights
Check prices for return flight
Best Flights from Myrtle Beach to Chicago Today
Take a look at the list of non stop flights and flights with layovers from Myrtle Beach to Chicago with the lowest price of $40. The fastest direct flight takes 2h 10m and the fastest connecting – 4h 52m.
| Price | Departure | Arrival | Flight Duration | Airline | Flight |
|---|---|---|---|---|---|
| from $40 | 11:36 Myrtle Beach AFB | 12:46 Chicago O'Hare International | 2h 10m | Spirit Airlines | NK2520 |
| from $116 | 16:55 Myrtle Beach AFB | 18:25 Chicago O'Hare International | 2h 30m | United Airlines | UA1923 |
| from $162 | 11:18 Myrtle Beach AFB | 12:55 Chicago O'Hare International | 2h 37m | United Airlines | UA3631 |
| from $280 | 11:35 Myrtle Beach AFB | 13:05 Chicago O'Hare International | 2h 30m | United Airlines | UA752 |
| from $64 | 17:32 Myrtle Beach AFB | 00:05+1 день Chicago O'Hare International | 7h 33m layover 2h 34m - Miami | Spirit Airlines | NK2656 NK1 |
| from $81 | 11:28 Myrtle Beach AFB | 18:44 Chicago O'Hare International | 8h 16m layover 3h 45m - Orlando | Spirit Airlines | NK2644 NK2190 |
| from $82 | 20:24 Myrtle Beach AFB | 20:23+1 день Chicago O'Hare International | 24h 59m layover 20h 25m - Orlando | Spirit Airlines | NK2089 NK2541 |
| from $85 | 10:07 Myrtle Beach AFB | 17:01 Chicago O'Hare International | 7h 54m layover 3h 53m - Philadelphia | Frontier Airlines | F93272 F92111 |
| from $105 | 19:06 Myrtle Beach AFB | 06:32+1 день Chicago O'Hare International | 12h 26m layover 8h 0m - Newark | Spirit Airlines | NK2115 NK2543 |
| from $105 | 05:15 Myrtle Beach AFB | 06:37+1 день Chicago O'Hare International | 26h 22m layover 22h 1m - Newark | Spirit Airlines | NK2650 NK2543 |
| from $101 | 18:12 Myrtle Beach AFB | 20:03+1 день Chicago O'Hare International | 26h 51m layover 19h 16m - Nashville 1h 1m - Orlando | Spirit Airlines | NK2248 NK2040 NK2541 |
| from $101 | 18:12 Myrtle Beach AFB | 20:03+1 день Chicago O'Hare International | 26h 51m layover 12h 46m - Nashville 7h 31m - Orlando | Spirit Airlines | NK2248 NK2241 NK2541 |
| from $101 | 18:12 Myrtle Beach AFB | 20:03+1 день Chicago O'Hare International | 26h 51m layover 16h 30m - Nashville 3h 48m - Orlando | Spirit Airlines | NK2248 NK2251 NK2541 |
| from $101 | 18:12 Myrtle Beach AFB | 23:29+1 день Chicago O'Hare International | 30h 17m layover 19h 16m - Nashville 4h 31m - Orlando | Spirit Airlines | NK2248 NK2040 NK2190 |
| from $101 | 18:12 Myrtle Beach AFB | 23:29+1 день Chicago O'Hare International | 30h 17m layover 16h 30m - Nashville 7h 18m - Orlando | Spirit Airlines | NK2248 NK2251 NK2190 |
| from $103 | 13:46 Myrtle Beach AFB | 18:10+1 день Chicago Midway | 29h 24m layover 6h 38m - Belleville 18h 4m - Knoxville | Allegiant Air | G43099 G41417 G43026 |
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on May 17, 2025
Flight Schedule Myrtle Beach (South Carolina) to Chicago (Illinois)
Full flight schedule will help you in detecting at what time planes fly from Myrtle Beach to Chicago. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
| Departure | Arrival | Flight Details | Flight Duration | Price |
|---|---|---|---|---|
|
11:18 — 12:55
|
11:18 — 12:55
UA3631
United Airlines
Myrtle Beach — Chicago
|
2h 37m |
Find flight
from$162 |
|
|
11:35 — 13:05
|
11:35 — 13:05
UA752
United Airlines
Myrtle Beach — Chicago
|
2h 30m |
Find flight
from$280 |
|
|
11:36 — 12:46
|
11:36 — 12:46
NK2520
Spirit Airlines
Myrtle Beach — Chicago
|
2h 10m |
Find flight
from$40 |
|
|
16:50 — 18:20
|
16:50 — 18:20
UA1580
United Airlines
Myrtle Beach — Chicago
|
2h 30m |
Find flight
from$180 |
|
|
16:55 — 18:25
|
16:55 — 18:25
UA1923
United Airlines
Myrtle Beach — Chicago
|
2h 30m |
Find flight
from$116 |
|
|
05:15 — 06:37
+1 day
|
05:10 — 06:59
NK2650
Spirit Airlines
Myrtle Beach — Newark
22h 1m stop
05:00 — 06:32
NK2543
Spirit Airlines
Newark — Chicago
|
26h 22m including layover |
Find flight
from$105 |
|
|
10:07 — 17:01
|
10:07 — 11:46
F93272
Frontier Airlines
Myrtle Beach — Philadelphia
3h 53m stop
15:39 — 17:01
F92111
Frontier Airlines
Philadelphia — Chicago
|
7h 54m including layover |
Find flight
from$85 |
|
|
11:28 — 18:44
|
06:00 — 07:28
NK2644
Spirit Airlines
Myrtle Beach — Orlando
3h 45m stop
21:25 — 23:29
NK2190
Spirit Airlines
Orlando — Chicago
|
8h 16m including layover |
Find flight
from$81 |
|
|
17:32 — 00:05
+1 day
|
17:32 — 19:18
NK2656
Spirit Airlines
Myrtle Beach — Miami
2h 34m stop
21:52 — 00:05
NK1
Spirit Airlines
Miami — Chicago
|
7h 33m including layover |
Find flight
from$64 |
|
|
17:32 — 08:50
+1 day
|
17:32 — 19:18
NK2656
Spirit Airlines
Myrtle Beach — Miami
11h 12m stop
06:30 — 08:50
NK2188
Spirit Airlines
Miami — Chicago
|
16h 18m including layover |
Find flight
from$108 |
|
|
19:06 — 06:32
+1 day
|
19:06 — 21:00
NK2115
Spirit Airlines
Myrtle Beach — Newark
8h stop
05:55 — 07:27
NK2543
Spirit Airlines
Newark — Chicago
|
12h 26m including layover |
Find flight
from$105 |
|
|
20:24 — 20:23
+1 day
|
19:25 — 21:00
NK2089
Spirit Airlines
Myrtle Beach — Orlando
20h 25m stop
17:55 — 20:03
NK2541
Spirit Airlines
Orlando — Chicago
|
24h 59m including layover |
Find flight
from$82 |
|
|
20:40 — 06:32
+1 day
|
20:40 — 22:23
NK2473
Spirit Airlines
Myrtle Beach — Newark
6h 37m stop
05:55 — 07:27
NK2543
Spirit Airlines
Newark — Chicago
|
10h 52m including layover |
Find flight
from$111 |
|
|
05:10 — 00:05
+1 day
|
05:10 — 06:59
NK2650
Spirit Airlines
Myrtle Beach — Newark
10h 40m stop
17:39 — 20:43
NK2692
Spirit Airlines
Newark — Miami
1h 9m stop
21:52 — 00:05
NK1
Spirit Airlines
Miami — Chicago
|
19h 55m including layover |
Find flight
from$113 |
|
|
06:00 — 18:40
|
06:00 — 07:28
NK2644
Spirit Airlines
Myrtle Beach — Orlando
49m stop
08:17 — 09:25
NK2196
Spirit Airlines
Orlando — Miami
6h 51m stop
16:16 — 18:40
NK19
Spirit Airlines
Miami — Chicago
|
13h 40m including layover |
Find flight
from$144 |
|
|
08:13 — 09:23
+1 day
|
06:00 — 07:28
NK2644
Spirit Airlines
Myrtle Beach — Orlando
4h 19m stop
09:31 — 11:46
NK2019
Spirit Airlines
Orlando — Baltimore
15h 52m stop
08:10 — 09:24
NK2439
Spirit Airlines
Baltimore — Chicago
|
26h 10m including layover |
Find flight
from$141 |
|
|
10:52 — 16:25
+1 day
|
10:52 — 12:49
G4408
Allegiant Air
Myrtle Beach — Albany
22h 42m stop
11:31 — 12:51
G4339
Allegiant Air
Albany — Nashville
1h 37m stop
14:28 — 16:25
NK2028
Spirit Airlines
Nashville — Chicago
|
30h 33m including layover |
Find flight
from$129 |
|
|
12:09 — 08:22
+1 day
|
12:09 — 13:34
G4982
Allegiant Air
Myrtle Beach — Lexington
9h 10m stop
22:44 — 23:26
G41481
Allegiant Air
Lexington — Fort Walton Beach
6h 34m stop
06:00 — 08:22
G41455
Allegiant Air
Fort Walton Beach — Chicago
|
21h 13m including layover |
Find flight
from$118 |
|
|
12:11 — 08:22
+1 day
|
12:11 — 13:38
G4982
Allegiant Air
Myrtle Beach — Lexington
2h stop
22:46 — 23:28
G43111
Allegiant Air
Lexington — Fort Walton Beach
13h 40m stop
06:00 — 08:22
G41455
Allegiant Air
Fort Walton Beach — Chicago
|
21h 11m including layover |
Find flight
from$116 |
|
|
13:46 — 18:10
+1 day
|
13:46 — 14:43
G43099
Allegiant Air
Myrtle Beach — Belleville
6h 38m stop
21:21 — 23:33
G41417
Allegiant Air
Belleville — Knoxville
18h 4m stop
17:37 — 18:10
G43026
Allegiant Air
Knoxville — Chicago
|
29h 24m including layover |
Find flight
from$103 |
|
|
13:46 — 08:22
+1 day
|
13:46 — 14:43
G43099
Allegiant Air
Myrtle Beach — Belleville
6h 53m stop
21:36 — 23:19
G43102
Allegiant Air
Belleville — Fort Walton Beach
6h 41m stop
06:00 — 08:22
G41455
Allegiant Air
Fort Walton Beach — Chicago
|
19h 36m including layover |
Find flight
from$112 |
|
|
14:29 — 14:03
+1 day
|
14:29 — 15:26
G43097
Allegiant Air
Myrtle Beach — Belleville
3h 34m stop
19:00 — 21:07
G41417
Allegiant Air
Belleville — Knoxville
16h 22m stop
13:29 — 14:03
G43062
Allegiant Air
Knoxville — Chicago
|
24h 34m including layover |
Find flight
from$106 |
|
|
14:29 — 08:22
+1 day
|
14:29 — 15:26
G43097
Allegiant Air
Myrtle Beach — Belleville
5h 36m stop
21:02 — 22:45
G43102
Allegiant Air
Belleville — Fort Walton Beach
7h 15m stop
06:00 — 08:22
G41455
Allegiant Air
Fort Walton Beach — Chicago
|
18h 53m including layover |
Find flight
from$122 |
|
|
15:12 — 08:50
+1 day
|
15:12 — 17:06
G4163
Allegiant Air
Myrtle Beach — Newburgh
2h 12m stop
19:18 — 22:43
G4523
Allegiant Air
Newburgh — Miami
7h 47m stop
06:30 — 08:50
NK2188
Spirit Airlines
Miami — Chicago
|
18h 38m including layover |
Find flight
from$132 |
|
|
15:21 — 08:50
+1 day
|
15:21 — 17:06
NK2648
Spirit Airlines
Myrtle Beach — Cleveland
2h 4m stop
19:10 — 22:01
NK2220
Spirit Airlines
Cleveland — Miami
8h 29m stop
06:30 — 08:50
NK2188
Spirit Airlines
Miami — Chicago
|
18h 29m including layover |
Find flight
from$129 |
|
|
16:42 — 09:24
+1 day
|
16:42 — 18:28
NK2656
Spirit Airlines
Myrtle Beach — Miami
1h 37m stop
20:05 — 22:41
NK2156
Spirit Airlines
Miami — Baltimore
9h 29m stop
08:10 — 09:24
NK2439
Spirit Airlines
Baltimore — Chicago
|
17h 42m including layover |
Find flight
from$141 |
|
|
18:12 — 20:03
+1 day
|
18:12 — 18:44
NK2248
Spirit Airlines
Myrtle Beach — Nashville
19h 16m stop
14:00 — 16:54
NK2040
Spirit Airlines
Nashville — Orlando
1h 1m stop
17:55 — 20:03
NK2541
Spirit Airlines
Orlando — Chicago
|
26h 51m including layover |
Find flight
from$101 |
|
|
18:12 — 20:03
+1 day
|
18:12 — 18:44
NK2248
Spirit Airlines
Myrtle Beach — Nashville
12h 46m stop
07:30 — 10:24
NK2241
Spirit Airlines
Nashville — Orlando
7h 31m stop
17:55 — 20:03
NK2541
Spirit Airlines
Orlando — Chicago
|
26h 51m including layover |
Find flight
from$101 |
|
|
19:06 — 20:03
+1 day
|
19:06 — 21:00
NK2115
Spirit Airlines
Myrtle Beach — Newark
55m stop
21:55 — 00:45
NK2116
Spirit Airlines
Newark — Orlando
17h 10m stop
17:55 — 20:03
NK2541
Spirit Airlines
Orlando — Chicago
|
25h 57m including layover |
Find flight
from$107 |
|
|
21:20 — 19:17
+1 day
|
21:20 — 23:25
NK2475
Spirit Airlines
Myrtle Beach — Detroit
6h 50m stop
06:15 — 07:02
NK2567
Spirit Airlines
Detroit — Minneapolis
10h 34m stop
17:36 — 19:17
SY261
Sun Country Airlines
Minneapolis — Chicago
|
22h 57m including layover |
Find flight
from$138 |
|
*Departure and arrival times - local. Updated on May 17, 2025
Flight Information
Below we will explain in detail what the flights cost on the destination from Myrtle Beach to Chicago depends on and how to choose the most interesting flight option for you.
Distance between Myrtle Beach and Chicago is 1189 miles. Time difference between the cities is 1h. Airplanes depart 05:10 to 21:46 from 2 Myrtle Beach airports and arrive 05:10 to 21:46 to 7 Chicago airports. Average flight time is 2h 30m.
- The fastest flight 2h 10m
- Average flight time 2h 30m
- The earliest flight 05:10
- The latest flight 21:46
- Distance 739 ml
The cheapest months to travel to Chicago are may (from 54 $), june (from 64 $).
What is the lowest airfare Myrtle Beach to Chicago?
The cheapest plane ticket found by our users is $40. This airfare is for economy class on one-way NK2520 flight by Spirit Airlines for May 30, 2025 which leaves AFB in Myrtle Beach at 11:36 am and arrives at Chicago O'Hare International at 12:46.
Economy class
$40
Business class
?
First class
?
Popular Airlines on the Route
The flight Myrtle Beach — Chicago is served by 6 regular airlines and 4 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 1 departures per week at the price of from $ 85 . And the most expensive tickets are offered by United Airlines airline - from $ 1529.
Direct flights
There are 5 nonstop flights on the route. The fastest direct flight is NK2520 by Spirit Airlines takes 2h 10m and the cheapest is NK2520 by Spirit Airlines for $40.
- UA - United Airlinesfrom $116Find
- NK - Spirit Airlinesfrom $40Find
See more direct flights
Connecting Flights
There are 233 flights with layovers on the route. The fastest connecting flight is UA4846 by United Airlines takes 4h 52m and the cheapest is NK2520 by Spirit Airlines for $64.
- F9 - Frontier Airlinesfrom $85Find
- SY - Sun Country Airlinesfrom $234Find
- MX - Mexicanafrom $177Find
- UA - United Airlinesfrom $192Find
- NK - Spirit Airlinesfrom $64Find
- G4 - Allegiant Airfrom $103Find
See more connecting flights
Airports
You can fly from Myrtle Beach to Chicago from 2 airports (AFB, Grand Strand Airport).
Myrtle Beach airports
- AFB-MYRfrom $40Find
- Grand Strand Airport-CREFind
Chicago airports
- O'Hare International-ORDFind
- Midway-MDWFind
- Dupage County-DPAFind
- Chicago FSS-CHIFind
- Merrill C Meigs (closed)-CGXFind
- Pal-Waukee-PWKFind
- Chicago NAS-NOHFind
Airplanes
There are flights to Chicago from Myrtle Beach by 6 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Myrtle Beach
You may also consider searching for discounted plane tickets to some other popular places from Myrtle Beach within United States.
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Top International Destinations from Myrtle Beach
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
- from $57Find
How to book a plane ticket yourself?
- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
- Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
- Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
- Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
- That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
To find a plane ticket, please select dates.