Cheap Flights from Myrtle Beach, SC to Chicago, IL from $69

On you will find 1 direct and 6 connecting flights from Myrtle Beach to Chicago. You can compare airfare deals from 2 airlines and multiple travel sites from $52, book and save on cheap plane tickets and last minute offers. Also check out MYR-CHI flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Myrtle Beach to Chicago Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $69 (one-way), $118 (round-trip).
Direct flights
  • Check to choose departure date Check to choose departure date
Check prices for return flight
Find flights
Full flight schedule will help you in detecting at what time planes fly from Myrtle Beach to Chicago. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
17:00 — 18:26
17:00 — 18:26 NK842 Spirit Airlines
Myrtle Beach — Chicago
2h 26m
Find flight
09:30 — 14:13
09:30 — 10:40 AA5243 American Airlines
Myrtle Beach — Charlotte
2h 35m stop
13:15 — 14:13 AA1650 American Airlines
Charlotte — Chicago
5h 43m
including layover
Find flight
11:18 — 15:53
11:18 — 12:29 AA5220 American Airlines
Myrtle Beach — Charlotte
2h 26m stop
14:55 — 15:53 AA1883 American Airlines
Charlotte — Chicago
5h 35m
including layover
Find flight
15:16 — 18:26
15:16 — 16:38 AA4440 American Airlines
Myrtle Beach — Washington D.C.
52m stop
17:30 — 18:26 AA1486 American Airlines
Washington D.C. — Chicago
4h 10m
including layover
Find flight
17:45 — 23:28
17:45 — 19:04 AA5311 American Airlines
Myrtle Beach — Charlotte
3h 26m stop
22:30 — 23:28 AA483 American Airlines
Charlotte — Chicago
6h 43m
including layover
Find flight
22:35 — 08:25
+1 day
22:35 — 00:38 NK126 Spirit Airlines
Myrtle Beach — Boston
5h 50m stop
06:28 — 08:25 B6111 JetBlue
Boston — Chicago
10h 50m
including layover
Find flight
18:11 — 07:27
+1 day
18:11 — 19:20 AA5311 American Airlines
Myrtle Beach — Charlotte
3h 20m stop
22:40 — 00:16 AA522 American Airlines
Charlotte — Dallas
4h 44m stop
05:00 — 07:27 AA2812 American Airlines
Dallas — Chicago
14h 16m
including layover
Find flight
*Departure and arrival times - local. Updated on February 3, 2023

Flight Information

Below we will explain in detail what the flights cost on the destination from Myrtle Beach to Chicago depends on and how to choose the most interesting flight option for you.

Distance between Myrtle Beach and Chicago is 1189 miles. Time difference between the cities is 1h. Airplanes depart 09:30 to 22:35 from 2 Myrtle Beach airports and arrive 09:30 to 22:35 to 7 Chicago airports. Average flight time is 2h 26m.

  • The fastest flight 2h 26m
  • Average flight time 2h 26m
  • The earliest flight 09:30
  • The latest flight 22:35
  • Distance 739 ml

What is the lowest airfare Myrtle Beach to Chicago?

The cheapest plane ticket found by our users is $52. This airfare is for economy class on one-way NK842 flight by Spirit Airlines for July 2, 2020 which leaves AFB in Myrtle Beach at 17:00 am and arrives at Chicago O'Hare International at 18:26.

Economy class
Business class
First class

Popular Airlines on the Route

The flight Myrtle Beach — Chicago is served by 2 regular airlines and 1 low-cost airline. Most of the flights on this route are operated by American Airlines - 5 departures per week at the price of from $ 221 . And the most expensive tickets are offered by American Airlines airline - from $ 409.

Direct flights

There are 1 nonstop flights on the route. The fastest direct flight is NK842 by Spirit Airlines takes 2h 26m and the cheapest is NK842 by Spirit Airlines for $52.

See more direct flights

Connecting Flights

There are 6 flights with layovers on the route. The fastest connecting flight is AA4440 by American Airlines takes 4h 10m and the cheapest is NK842 by Spirit Airlines for $211.

See more connecting flights


You can fly from Myrtle Beach to Chicago from 2 airports (AFB, Grand Strand Airport).

Myrtle Beach airports

    from $52
  • Grand Strand Airport-CRE

Chicago airports

  • O'Hare International-ORD
  • Midway-MDW
  • Dupage County-DPA
  • Chicago FSS-CHI
  • Merrill C Meigs (closed)-CGX
  • Pal-Waukee-PWK
  • Chicago NAS-NOH

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.