Cheap Flights from Myrtle Beach, SC to Chicago, IL from $37

On Cheapflightsplus.com you will find 179 connecting flights from Myrtle Beach to Chicago. You can compare airfare deals from 4 airlines and multiple travel sites from $37, book and save on cheap plane tickets and last minute offers. Also check out MYR-CHI flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Myrtle Beach to Chicago Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $37 (one-way), $63 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Myrtle Beach to Chicago. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
05:00 — 09:55
06:22 — 08:08 NK3646 Spirit Airlines
Myrtle Beach — Miami
48m stop
12:56 — 15:16 NK2 Spirit Airlines
Miami — Chicago
5h 55m
including layover
Find flight
from$99
05:00 — 15:57
05:00 — 06:52 NK3646 Spirit Airlines
Myrtle Beach — Miami
6h 48m stop
13:40 — 15:57 NK327 Spirit Airlines
Miami — Chicago
11h 57m
including layover
Find flight
from$118
06:00 — 16:06
06:00 — 07:49 NK3646 Spirit Airlines
Myrtle Beach — Miami
5h 54m stop
13:43 — 16:06 NK157 Spirit Airlines
Miami — Chicago
11h 6m
including layover
Find flight
from$99
09:15 — 20:13
09:15 — 11:05 NK293 Spirit Airlines
Myrtle Beach — Miami
6h 45m stop
17:50 — 20:13 NK19 Spirit Airlines
Miami — Chicago
11h 58m
including layover
Find flight
from$114
11:04 — 16:06
11:04 — 12:53 NK947 Spirit Airlines
Myrtle Beach — Miami
50m stop
13:43 — 16:06 NK157 Spirit Airlines
Miami — Chicago
6h 2m
including layover
Find flight
from$99
11:04 — 21:07
11:04 — 12:53 NK947 Spirit Airlines
Myrtle Beach — Miami
5h 52m stop
18:45 — 21:07 NK7 Spirit Airlines
Miami — Chicago
11h 3m
including layover
Find flight
from$99
12:45 — 22:06
12:45 — 14:30 NK3389 Spirit Airlines
Myrtle Beach — New York
5h 59m stop
20:29 — 22:06 NK3386 Spirit Airlines
New York — Chicago
10h 21m
including layover
Find flight
from$37
13:53 — 18:39
13:53 — 16:00 UA3638 United Airlines
Myrtle Beach — Newark
1h stop
17:00 — 18:39 UA661 United Airlines
Newark — Chicago
5h 46m
including layover
Find flight
from$274
13:53 — 08:59
+1 day
13:53 — 16:00 UA3638 United Airlines
Myrtle Beach — Newark
15h 15m stop
07:15 — 08:59 UA1044 United Airlines
Newark — Chicago
20h 6m
including layover
Find flight
from$298
14:53 — 20:17
13:53 — 16:00 UA3638 United Airlines
Myrtle Beach — Newark
1h 40m stop
18:25 — 20:07 UA254 United Airlines
Newark — Chicago
6h 24m
including layover
Find flight
from$274
14:53 — 22:03
13:53 — 16:00 UA3638 United Airlines
Myrtle Beach — Newark
3h 30m stop
19:43 — 21:22 UA546 United Airlines
Newark — Chicago
8h 10m
including layover
Find flight
from$274
15:19 — 23:07
15:19 — 17:16 G4179 Allegiant Air
Myrtle Beach — New York
4h 13m stop
21:29 — 23:07 NK3386 Spirit Airlines
New York — Chicago
8h 48m
including layover
Find flight
from$192
15:19 — 00:34
+1 day
15:19 — 17:16 G4179 Allegiant Air
Myrtle Beach — Newark
5h 39m stop
22:55 — 00:34 NK329 Spirit Airlines
Newark — Chicago
10h 15m
including layover
Find flight
from$196
16:41 — 20:58
16:41 — 18:23 NK137 Spirit Airlines
Myrtle Beach — Orlando
31m stop
18:54 — 20:58 NK1842 Spirit Airlines
Orlando — Chicago
5h 17m
including layover
Find flight
from$53
17:21 — 21:53
17:21 — 19:02 NK137 Spirit Airlines
Myrtle Beach — Orlando
48m stop
19:50 — 21:53 NK1147 Spirit Airlines
Orlando — Chicago
5h 32m
including layover
Find flight
from$118
18:38 — 22:43
18:38 — 20:24 NK897 Spirit Airlines
Myrtle Beach — New York
41m stop
21:05 — 22:43 NK3386 Spirit Airlines
New York — Chicago
5h 5m
including layover
Find flight
from$118
19:09 — 00:34
+1 day
19:09 — 20:59 NK992 Spirit Airlines
Myrtle Beach — Newark
1h 56m stop
22:55 — 00:34 NK329 Spirit Airlines
Newark — Chicago
6h 25m
including layover
Find flight
from$73
06:22 — 23:59
06:22 — 08:08 NK3646 Spirit Airlines
Myrtle Beach — Miami
6h 37m stop
14:45 — 15:45 NK322 Spirit Airlines
Miami — Tampa
6h 35m stop
22:20 — 23:59 NK139 Spirit Airlines
Tampa — Chicago
18h 37m
including layover
Find flight
from$161
09:15 — 22:55
09:15 — 11:05 NK293 Spirit Airlines
Myrtle Beach — Miami
5h 2m stop
16:07 — 19:00 NK220 Spirit Airlines
Miami — New York
2h 15m stop
21:15 — 22:55 NK225 Spirit Airlines
New York — Chicago
14h 40m
including layover
Find flight
from$106
12:54 — 07:18
+1 day
12:54 — 14:30 NK2965 Spirit Airlines
Myrtle Beach — New York
5h 35m stop
20:05 — 23:10 NK221 Spirit Airlines
New York — Orlando
6h stop
05:10 — 07:18 NK1683 Spirit Airlines
Orlando — Chicago
19h 24m
including layover
Find flight
from$98
22:38 — 13:44
+1 day
22:38 — 00:23 NK1002 Spirit Airlines
Myrtle Beach — Miami
6h 42m stop
07:05 — 10:00 NK371 Spirit Airlines
Miami — Newark
2h 8m stop
12:08 — 13:44 NK329 Spirit Airlines
Newark — Chicago
16h 6m
including layover
Find flight
from$150
22:38 — 13:44
+1 day
22:38 — 00:23 NK1002 Spirit Airlines
Myrtle Beach — Miami
5h 42m stop
06:05 — 09:00 NK385 Spirit Airlines
Miami — Newark
3h 8m stop
12:08 — 13:44 NK329 Spirit Airlines
Newark — Chicago
16h 6m
including layover
Find flight
from$150
*Departure and arrival times - local. Updated on April 4, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Myrtle Beach to Chicago depends on and how to choose the most interesting flight option for you.

Distance between Myrtle Beach and Chicago is 1189 miles. Time difference between the cities is 1h. Airplanes depart 05:00 to 22:38 from 2 Myrtle Beach airports and arrive 05:00 to 22:38 to 7 Chicago airports. Average flight time is 17h 49m.

  • The fastest flight 5h 5m
  • Average flight time 17h 49m
  • The earliest flight 05:00
  • The latest flight 22:38
  • Distance 739 ml

The cheapest months to travel to Chicago are november (from 37 $), december (from 53 $), january (from 98 $).

The most expensive months are february (from 118 $), january (from 98 $), december (from 53 $).

What is the lowest airfare Myrtle Beach to Chicago?

The cheapest plane ticket found by our users is $37. This airfare is for economy class on one-way NK3389 flight by Spirit Airlines for November 19, 2024 which leaves AFB in Myrtle Beach at 12:45 am and arrives at Chicago O'Hare International at 22:06.

Economy class
$37
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Business class
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First class
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Popular Airlines on the Route

The flight Myrtle Beach — Chicago is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Mexicana - 1 departures per week at the price of from $ 189 . And the most expensive tickets are offered by Spirit Airlines airline - from $ 768.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 179 flights with layovers on the route. The fastest connecting flight is NK897 by Spirit Airlines takes 5h 5m and the cheapest is NK3389 by Spirit Airlines for $37.

  • MX - Mexicana
    from $189
    Find
  • UA - United Airlines
    from $274
    Find
  • NK - Spirit Airlines
    from $37
    Find
  • G4 - Allegiant Air
    from $192
    Find
See more connecting flights

Airports

You can fly from Myrtle Beach to Chicago from 2 airports (AFB, Grand Strand Airport).

Myrtle Beach airports

  • AFB-MYR
    from $37
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  • Grand Strand Airport-CRE
    Find

Chicago airports

  • O'Hare International-ORD
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  • Midway-MDW
    Find
  • Dupage County-DPA
    Find
  • Chicago FSS-CHI
    Find
  • Merrill C Meigs (closed)-CGX
    Find
  • Pal-Waukee-PWK
    Find
  • Chicago NAS-NOH
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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