Cheap Flights from Myrtle Beach, SC to Detroit, MI from $54

On Cheapflightsplus.com you will find 3 direct and 279 connecting flights from Myrtle Beach to Detroit. You can compare airfare deals from 4 airlines and multiple travel sites from $54, book and save on cheap plane tickets and last minute offers. Also check out MYR-DTT flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Myrtle Beach to Detroit Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $54 (one-way), $93 (round-trip).
Direct flights
  • Check to choose departure date Check to choose departure date
Check prices for return flight
Find flights
Full flight schedule will help you in detecting at what time planes fly from Myrtle Beach to Detroit. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
12:18 — 14:12
12:18 — 14:12 NK3184 Spirit Airlines
Myrtle Beach — Detroit
1h 54m
Find flight
from$54
20:57 — 23:01
20:57 — 23:01 NK1007 Spirit Airlines
Myrtle Beach — Detroit
2h 4m
Find flight
from$54
21:20 — 23:25
21:20 — 23:25 NK2475 Spirit Airlines
Myrtle Beach — Detroit
2h 5m
Find flight
from$54
05:00 — 11:58
05:00 — 06:52 NK3646 Spirit Airlines
Myrtle Beach — Miami
2h 7m stop
08:59 — 11:58 NK380 Spirit Airlines
Miami — Detroit
6h 58m
including layover
Find flight
from$78
05:00 — 17:49
05:00 — 06:52 NK3646 Spirit Airlines
Myrtle Beach — Miami
7h 58m stop
14:50 — 17:49 NK3722 Spirit Airlines
Miami — Detroit
12h 49m
including layover
Find flight
from$78
06:00 — 12:10
06:00 — 07:55 NK2845 Spirit Airlines
Myrtle Beach — Hartford
2h 24m stop
10:19 — 12:10 NK2012 Spirit Airlines
Hartford — Detroit
6h 10m
including layover
Find flight
from$78
06:10 — 12:53
06:10 — 07:32 NK1289 Spirit Airlines
Myrtle Beach — Orlando
2h 31m stop
10:03 — 12:53 NK1528 Spirit Airlines
Orlando — Detroit
6h 43m
including layover
Find flight
from$78
07:00 — 14:40
07:00 — 09:03 NK1805 Spirit Airlines
Myrtle Beach — Boston
3h 23m stop
12:26 — 14:40 NK1197 Spirit Airlines
Boston — Detroit
7h 40m
including layover
Find flight
from$108
08:34 — 15:55
08:34 — 10:40 NK893 Spirit Airlines
Myrtle Beach — Boston
3h 15m stop
13:55 — 15:55 NK2328 Spirit Airlines
Boston — Detroit
7h 21m
including layover
Find flight
from$78
08:50 — 14:44
08:50 — 10:41 NK992 Spirit Airlines
Myrtle Beach — Newark
2h 13m stop
12:54 — 14:44 NK298 Spirit Airlines
Newark — Detroit
5h 54m
including layover
Find flight
from$78
10:33 — 14:44
10:33 — 12:23 NK3020 Spirit Airlines
Myrtle Beach — Newark
31m stop
12:54 — 14:44 NK298 Spirit Airlines
Newark — Detroit
4h 11m
including layover
Find flight
from$78
10:33 — 21:42
10:33 — 12:23 NK3020 Spirit Airlines
Myrtle Beach — Newark
7h 27m stop
19:50 — 21:42 NK2319 Spirit Airlines
Newark — Detroit
11h 9m
including layover
Find flight
from$112
11:28 — 20:11
11:28 — 12:53 NK2644 Spirit Airlines
Myrtle Beach — Orlando
4h 25m stop
17:18 — 20:11 NK2455 Spirit Airlines
Orlando — Detroit
8h 43m
including layover
Find flight
from$131
14:52 — 23:29
14:52 — 16:40 NK2965 Spirit Airlines
Myrtle Beach — New York
4h 47m stop
21:27 — 23:29 NK3392 Spirit Airlines
New York — Detroit
8h 37m
including layover
Find flight
from$78
14:52 — 14:44
+1 day
14:52 — 16:40 NK2965 Spirit Airlines
Myrtle Beach — Newark
20h 14m stop
12:54 — 14:44 NK298 Spirit Airlines
Newark — Detroit
23h 52m
including layover
Find flight
from$109
16:08 — 15:55
+1 day
16:08 — 18:18 NK138 Spirit Airlines
Myrtle Beach — Boston
19h 37m stop
13:55 — 15:55 NK2328 Spirit Airlines
Boston — Detroit
23h 47m
including layover
Find flight
from$132
16:44 — 22:20
12:26 — 14:31 NK2658 Spirit Airlines
Myrtle Beach — Boston
1h 14m stop
20:03 — 22:20 NK2152 Spirit Airlines
Boston — Detroit
5h 36m
including layover
Find flight
from$83
18:04 — 08:07
+1 day
18:04 — 19:33 NK137 Spirit Airlines
Myrtle Beach — Orlando
9h 52m stop
05:25 — 08:07 NK3785 Spirit Airlines
Orlando — Detroit
14h 3m
including layover
Find flight
from$117
19:13 — 08:01
+1 day
19:13 — 21:10 NK1809 Spirit Airlines
Myrtle Beach — New York
8h 49m stop
05:59 — 08:01 NK1190 Spirit Airlines
New York — Detroit
12h 48m
including layover
Find flight
from$99
19:13 — 08:12
+1 day
19:13 — 21:10 NK1809 Spirit Airlines
Myrtle Beach — Newark
9h stop
06:10 — 08:12 NK1414 Spirit Airlines
Newark — Detroit
12h 59m
including layover
Find flight
from$99
20:30 — 08:12
+1 day
20:30 — 22:12 NK1696 Spirit Airlines
Myrtle Beach — Newark
7h 58m stop
06:10 — 08:12 NK1414 Spirit Airlines
Newark — Detroit
11h 42m
including layover
Find flight
from$112
07:30 — 14:44
+1 day
07:30 — 09:01 NK3182 Spirit Airlines
Myrtle Beach — Pittsburgh
10h 55m stop
19:56 — 21:23 NK3748 Spirit Airlines
Pittsburgh — Newark
15h 31m stop
12:54 — 14:44 NK298 Spirit Airlines
Newark — Detroit
31h 14m
including layover
Find flight
from$134
17:07 — 08:12
+1 day
17:07 — 17:40 NK1492 Spirit Airlines
Myrtle Beach — Nashville
3h 10m stop
20:50 — 23:59 NK1419 Spirit Airlines
Nashville — Newark
6h 11m stop
06:10 — 08:12 NK1414 Spirit Airlines
Newark — Detroit
15h 5m
including layover
Find flight
from$122
17:07 — 22:54
+1 day
17:07 — 17:40 NK1492 Spirit Airlines
Myrtle Beach — Nashville
3h 10m stop
20:50 — 23:59 NK1419 Spirit Airlines
Nashville — Newark
20h 46m stop
20:45 — 22:54 NK1079 Spirit Airlines
Newark — Detroit
29h 47m
including layover
Find flight
from$122
18:04 — 08:42
+1 day
18:04 — 19:33 NK137 Spirit Airlines
Myrtle Beach — Orlando
2h 27m stop
22:00 — 23:15 NK3136 Spirit Airlines
Orlando — Atlanta
7h 30m stop
06:45 — 08:42 NK1156 Spirit Airlines
Atlanta — Detroit
14h 38m
including layover
Find flight
from$125
21:47 — 00:42
+2 days
21:47 — 23:25 G4407 Allegiant Air
Myrtle Beach — Covington
8h 46m stop
08:11 — 10:40 G4391 Allegiant Air
Covington — Miami
11h stop
21:40 — 00:42 NK1051 Spirit Airlines
Miami — Detroit
26h 55m
including layover
Find flight
from$124
*Departure and arrival times - local. Updated on June 7, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Myrtle Beach to Detroit depends on and how to choose the most interesting flight option for you.

Distance between Myrtle Beach and Detroit is 1027 miles. Time difference between the cities is 0h. Airplanes depart 05:00 to 21:47 from 2 Myrtle Beach airports and arrive 05:00 to 21:47 to 2 Detroit airports. Average flight time is 2h 4m.

  • The fastest flight 1h 54m
  • Average flight time 2h 4m
  • The earliest flight 05:00
  • The latest flight 21:47
  • Distance 639 ml

The cheapest months to travel to Detroit are july (from 72 $), august (from 72 $), october (from 111 $).

The most expensive months are september (from 111 $), october (from 111 $), august (from 72 $).

What is the lowest airfare Myrtle Beach to Detroit?

The cheapest plane ticket found by our users is $54. This airfare is for economy class on one-way NK2475 flight by Spirit Airlines for July 6, 2025 which leaves AFB in Myrtle Beach at 21:20 am and arrives at Detroit All airports at 23:25.

Economy class
$54
Find
Business class
?
Find
First class
?
Find

Popular Airlines on the Route

The flight Myrtle Beach — Detroit is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Mexicana - 6 departures per week at the price of from $ 162 . And the most expensive tickets are offered by United Airlines airline - from $ 454.

Direct flights

There are 3 nonstop flights on the route. The fastest direct flight is NK3184 by Spirit Airlines takes 1h 54m and the cheapest is NK2475 by Spirit Airlines for $54.

  • NK - Spirit Airlines
    from $54
    Find
See more direct flights

Connecting Flights

There are 279 flights with layovers on the route. The fastest connecting flight is NK3020 by Spirit Airlines takes 4h 11m and the cheapest is NK2475 by Spirit Airlines for $78.

  • MX - Mexicana
    from $162
    Find
  • UA - United Airlines
    from $162
    Find
  • NK - Spirit Airlines
    from $78
    Find
  • G4 - Allegiant Air
    from $124
    Find
See more connecting flights

Airports

You can fly from Myrtle Beach to Detroit from 2 airports (AFB, Grand Strand Airport).

Myrtle Beach airports

  • AFB-MYR
    from $54
    Find
  • Grand Strand Airport-CRE
    Find

Detroit airports

  • Willow Run-YIP
    Find
  • Detroit City-DET
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back