Cheap Flights from Myrtle Beach, SC to Pittsburgh, PA from $134

On Cheapflightsplus.com you will find 62 connecting flights from Myrtle Beach to Pittsburgh. You can compare airfare deals from 4 airlines and multiple travel sites from $134, book and save on cheap plane tickets and last minute offers. Also check out MYR-PIT flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Myrtle Beach to Pittsburgh depends on and how to choose the most interesting flight option for you.

Distance between Myrtle Beach and Pittsburgh is 766 miles. Time difference between the cities is 0h. Airplanes depart 08:00 to 21:04 from 2 Myrtle Beach airports and arrive 08:00 to 21:04 to 3 Pittsburgh airports. Average flight time is 22h 11m.

  • The fastest flight 4h 50m
  • Average flight time 22h 11m
  • The earliest flight 08:00
  • The latest flight 21:04
  • Distance 476 ml

The cheapest months to travel to Pittsburgh are august (from 134 $).

What is the lowest airfare Myrtle Beach to Pittsburgh?

The cheapest plane ticket found by our users is $134. This airfare is for economy class on one-way NK2362 flight by Spirit Airlines for August 20, 2025 which leaves AFB in Myrtle Beach at 19:43 am and arrives at Pittsburgh Pittsburgh Int. at 19:56.

Economy class
$134
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Business class
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First class
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Flight Schedule Myrtle Beach (South Carolina) to Pittsburgh (Pennsylvania)

10:35 — 17:04+1day
30h 29m flight time
Find flight
from$149
10:35 — 12:26 Myrtle Beach — New Haven
XP492 Casino Express
22h 9m stop
10:35 — 12:07 New Haven — Nashville
XP624 Casino Express
2h 24m stop
14:31 — 17:04 Nashville — Pittsburgh
G42727 Allegiant Air
12:13 — 19:56+1day
31h 43m flight time
Find flight
from$161
12:13 — 13:50 Myrtle Beach — Akron
MX730 Mexicana
20h 48m stop
10:38 — 12:51 Akron — Sanford
G41262 Allegiant Air
4h 51m stop
17:42 — 19:56 Sanford — Pittsburgh
G42742 Allegiant Air
14:00 — 19:56+1day
29h 56m flight time
Find flight
from$143
14:00 — 15:53 Myrtle Beach — Newark
NK2404 Spirit Airlines
4h 7m stop
20:00 — 22:52 Newark — Sanford
NK2819 Spirit Airlines
18h 50m stop
17:42 — 19:56 Sanford — Pittsburgh
G42742 Allegiant Air
14:00 — 09:15+1day
19h 15m flight time
Find flight
from$147
14:00 — 15:53 Myrtle Beach — Newark
NK2404 Spirit Airlines
4h 7m stop
20:00 — 22:52 Newark — Orlando
NK2819 Spirit Airlines
8h 8m stop
07:00 — 09:15 Orlando — Pittsburgh
NK412 Spirit Airlines
14:00 — 17:05+1day
27h 5m flight time
Find flight
from$147
14:00 — 15:53 Myrtle Beach — Newark
NK2404 Spirit Airlines
4h 7m stop
20:00 — 22:52 Newark — Orlando
NK2819 Spirit Airlines
15h 50m stop
14:42 — 17:05 Orlando — Pittsburgh
NK2446 Spirit Airlines
14:40 — 19:56+1day
29h 16m flight time
Find flight
from$156
14:40 — 16:24 Myrtle Beach — Miami
NK2356 Spirit Airlines
5h 21m stop
21:45 — 22:52 Miami — Sanford
NK2204 Spirit Airlines
18h 50m stop
17:42 — 19:56 Sanford — Pittsburgh
G42742 Allegiant Air
14:40 — 17:04+1day
26h 24m flight time
Find flight
from$159
14:40 — 16:24 Myrtle Beach — Miami
NK2356 Spirit Airlines
4h 25m stop
20:49 — 22:09 Miami — Nashville
NK2326 Spirit Airlines
16h 22m stop
14:31 — 17:04 Nashville — Pittsburgh
G42727 Allegiant Air
14:40 — 09:15+1day
18h 35m flight time
Find flight
from$160
14:40 — 16:24 Myrtle Beach — Miami
NK2356 Spirit Airlines
5h 21m stop
21:45 — 22:52 Miami — Orlando
NK2204 Spirit Airlines
8h 8m stop
07:00 — 09:15 Orlando — Pittsburgh
NK412 Spirit Airlines
14:40 — 17:05+1day
26h 25m flight time
Find flight
from$160
14:40 — 16:24 Myrtle Beach — Miami
NK2356 Spirit Airlines
5h 21m stop
21:45 — 22:52 Miami — Orlando
NK2204 Spirit Airlines
15h 50m stop
14:42 — 17:05 Orlando — Pittsburgh
NK2446 Spirit Airlines
16:45 — 23:44
6h 59m flight time
Find flight
from$135
16:45 — 18:14 Myrtle Beach — Chicago
UA444 United Airlines
2h 53m stop
21:07 — 23:44 Chicago — Pittsburgh
UA3464 United Airlines
19:43 — 19:56+1day
24h 13m flight time
Find flight
from$134
19:43 — 21:12 Myrtle Beach — Sanford
NK2362 Spirit Airlines
20h 30m stop
17:42 — 19:56 Sanford — Pittsburgh
G42742 Allegiant Air
19:43 — 09:15+1day
13h 32m flight time
Find flight
from$138
19:43 — 21:12 Myrtle Beach — Orlando
NK2362 Spirit Airlines
9h 48m stop
07:00 — 09:15 Orlando — Pittsburgh
NK412 Spirit Airlines
19:43 — 17:05+1day
21h 22m flight time
Find flight
from$138
19:43 — 21:12 Myrtle Beach — Orlando
NK2362 Spirit Airlines
17h 30m stop
14:42 — 17:05 Orlando — Pittsburgh
NK2446 Spirit Airlines
19:43 — 18:17+1day
22h 34m flight time
Find flight
from$145
19:43 — 21:12 Myrtle Beach — Orlando
NK2362 Spirit Airlines
18h 29m stop
15:41 — 18:17 Orlando — Pittsburgh
F91620 Frontier Airlines
19:43 — 17:04+1day
21h 21m flight time
Find flight
from$159
19:43 — 21:12 Myrtle Beach — Orlando
NK2362 Spirit Airlines
1h 12m stop
22:24 — 23:20 Orlando — Nashville
NK2535 Spirit Airlines
15h 11m stop
14:31 — 17:04 Nashville — Pittsburgh
G42727 Allegiant Air
Full flight schedule will help you in detecting at what time planes fly from Myrtle Beach to Pittsburgh. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on September 28, 2025.

Popular Airlines on the Route

The flight Myrtle Beach — Pittsburgh is served by 4 regular airlines and 1 low-cost airline. Most of the flights on this route are operated by Casino Express - 1 departures per week at the price of from $ 149 . And the most expensive tickets are offered by United Airlines airline - from $ 572.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 62 flights with layovers on the route. The fastest connecting flight is UA661 by United Airlines takes 4h 50m and the cheapest is NK2362 by Spirit Airlines for $134.

  • XP - Casino Express
    from $149
    Find
  • MX - Mexicana
    from $161
    Find
  • UA - United Airlines
    from $135
    Find
  • NK - Spirit Airlines
    from $134
    Find
See more connecting flights

Airports

You can fly from Myrtle Beach to Pittsburgh from 2 airports (AFB, Grand Strand Airport).

Myrtle Beach airports

  • AFB-MYR
    from $134
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  • Grand Strand Airport-CRE
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Pittsburgh airports

  • Allegheny County-AGC
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  • Pittsburgh Int.-PIT
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  • Civic Ar Heli-CVA
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

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