Cheap Flights from Myrtle Beach, SC to Pittsburgh, PA from $45

On Cheapflightsplus.com you will find 8 direct and 300 connecting flights from Myrtle Beach to Pittsburgh. You can compare airfare deals from 5 airlines and multiple travel sites from $45, book and save on cheap plane tickets and last minute offers. Also check out MYR-PIT flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Myrtle Beach to Pittsburgh Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $45 (one-way), $77 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Myrtle Beach to Pittsburgh. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
07:30 — 09:01
07:30 — 09:01 NK3182 Spirit Airlines
Myrtle Beach — Pittsburgh
1h 31m
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from$77
08:49 — 10:19
08:49 — 10:19 G41127 Allegiant Air
Myrtle Beach — Pittsburgh
1h 30m
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from$88
12:21 — 13:49
12:21 — 13:49 NK1487 Spirit Airlines
Myrtle Beach — Pittsburgh
1h 28m
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from$73
16:31 — 18:02
16:31 — 18:02 G43683 Allegiant Air
Myrtle Beach — Pittsburgh
1h 31m
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from$81
19:26 — 20:56
19:26 — 20:56 G42734 Allegiant Air
Myrtle Beach — Pittsburgh
1h 30m
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from$75
19:30 — 21:00
19:30 — 21:00 G42751 Allegiant Air
Myrtle Beach — Pittsburgh
1h 30m
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from$88
19:56 — 21:26
19:56 — 21:26 G41105 Allegiant Air
Myrtle Beach — Pittsburgh
1h 30m
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from$88
21:24 — 22:52
21:24 — 22:52 NK2756 Spirit Airlines
Myrtle Beach — Pittsburgh
1h 28m
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from$45
05:00 — 10:36
05:00 — 06:52 NK3646 Spirit Airlines
Myrtle Beach — Miami
1h 8m stop
08:00 — 10:36 NK1676 Spirit Airlines
Miami — Pittsburgh
5h 36m
including layover
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from$116
05:15 — 09:16
05:10 — 06:59 NK2650 Spirit Airlines
Myrtle Beach — Newark
1h stop
07:59 — 09:20 NK2651 Spirit Airlines
Newark — Pittsburgh
4h 1m
including layover
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from$91
06:10 — 20:46
06:00 — 07:28 NK2644 Spirit Airlines
Myrtle Beach — Sanford
11h 3m stop
18:50 — 21:01 G41138 Allegiant Air
Sanford — Pittsburgh
14h 36m
including layover
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from$119
06:10 — 20:46
06:10 — 07:32 NK1289 Spirit Airlines
Myrtle Beach — Sanford
11h 3m stop
18:35 — 20:46 G41138 Allegiant Air
Sanford — Pittsburgh
14h 36m
including layover
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from$122
08:34 — 23:29
08:34 — 10:30 NK1003 Spirit Airlines
Myrtle Beach — Newark
11h 35m stop
22:05 — 23:29 NK1788 Spirit Airlines
Newark — Pittsburgh
14h 55m
including layover
Find flight
from$126
10:33 — 19:01
10:33 — 12:23 NK3020 Spirit Airlines
Myrtle Beach — Newark
5h 12m stop
17:35 — 19:01 NK3747 Spirit Airlines
Newark — Pittsburgh
8h 28m
including layover
Find flight
from$112
11:25 — 15:41
11:25 — 13:27 UA3699 United Airlines
Myrtle Beach — Newark
47m stop
14:14 — 15:41 UA3623 United Airlines
Newark — Pittsburgh
4h 16m
including layover
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from$132
11:28 — 17:40
10:58 — 13:04 UA2630 United Airlines
Myrtle Beach — Newark
2h 49m stop
16:00 — 17:37 UA3528 United Airlines
Newark — Pittsburgh
6h 12m
including layover
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from$134
13:40 — 14:00
+1 day
13:40 — 15:17 MX173 Mexicana
Myrtle Beach — Clearwater
20h 25m stop
11:42 — 14:00 G42770 Allegiant Air
Clearwater — Pittsburgh
24h 20m
including layover
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from$190
13:40 — 16:40
+1 day
13:40 — 15:17 MX173 Mexicana
Myrtle Beach — Clearwater
23h 4m stop
14:21 — 16:40 G42792 Allegiant Air
Clearwater — Pittsburgh
27h
including layover
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from$191
14:40 — 18:48
14:40 — 16:12 UA4334 United Airlines
Myrtle Beach — Washington D.C.
1h 33m stop
17:45 — 18:48 UA543 United Airlines
Washington D.C. — Pittsburgh
4h 8m
including layover
Find flight
from$152
15:29 — 23:29
15:29 — 17:21 G4211 Allegiant Air
Myrtle Beach — Newark
4h 44m stop
22:05 — 23:29 NK1788 Spirit Airlines
Newark — Pittsburgh
8h
including layover
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from$110
16:45 — 23:44
16:45 — 18:22 UA5335 United Airlines
Myrtle Beach — Chicago
2h 45m stop
21:07 — 23:44 UA3464 United Airlines
Chicago — Pittsburgh
6h 59m
including layover
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from$135
17:16 — 23:39
17:16 — 19:11 UA1555 United Airlines
Myrtle Beach — Newark
2h 48m stop
21:59 — 23:39 UA3477 United Airlines
Newark — Pittsburgh
6h 23m
including layover
Find flight
from$154
17:25 — 23:35
17:12 — 19:21 UA3714 United Airlines
Myrtle Beach — Newark
2h 26m stop
21:59 — 23:42 UA3477 United Airlines
Newark — Pittsburgh
6h 10m
including layover
Find flight
from$132
18:04 — 23:55
18:04 — 19:33 NK137 Spirit Airlines
Myrtle Beach — Orlando
2h stop
21:33 — 23:55 NK1316 Spirit Airlines
Orlando — Pittsburgh
5h 51m
including layover
Find flight
from$91
18:04 — 20:09
+1 day
18:04 — 19:33 NK137 Spirit Airlines
Myrtle Beach — Sanford
22h 22m stop
17:55 — 20:09 G41205 Allegiant Air
Sanford — Pittsburgh
26h 5m
including layover
Find flight
from$166
10:33 — 23:55
10:33 — 12:23 NK3020 Spirit Airlines
Myrtle Beach — Newark
4h 22m stop
16:45 — 19:35 NK1900 Spirit Airlines
Newark — Orlando
1h 58m stop
21:33 — 23:55 NK1316 Spirit Airlines
Orlando — Pittsburgh
13h 22m
including layover
Find flight
from$160
12:11 — 11:40
+1 day
12:09 — 13:34 G4982 Allegiant Air
Myrtle Beach — Lexington
9h 5m stop
22:44 — 23:26 G41481 Allegiant Air
Lexington — Fort Walton Beach
9h 7m stop
08:32 — 11:40 G42725 Allegiant Air
Fort Walton Beach — Pittsburgh
23h 29m
including layover
Find flight
from$153
14:52 — 23:55
+1 day
14:52 — 16:40 NK2965 Spirit Airlines
Myrtle Beach — Newark
23h 30m stop
16:10 — 19:00 NK502 Spirit Airlines
Newark — Orlando
2h 33m stop
21:33 — 23:55 NK1316 Spirit Airlines
Orlando — Pittsburgh
33h 3m
including layover
Find flight
from$157
20:24 — 22:21
+1 day
19:25 — 21:00 NK2089 Spirit Airlines
Myrtle Beach — Orlando
10h 35m stop
08:17 — 09:25 NK2196 Spirit Airlines
Orlando — Miami
9h 59m stop
21:12 — 23:54 NK2634 Spirit Airlines
Miami — Pittsburgh
25h 57m
including layover
Find flight
from$153
20:40 — 21:37
+1 day
20:40 — 22:50 G4566 Allegiant Air
Myrtle Beach — Grand Rapids
7h 10m stop
06:00 — 07:44 G4561 Allegiant Air
Grand Rapids — Austin
9h 58m stop
17:42 — 21:37 G42728 Allegiant Air
Austin — Pittsburgh
24h 57m
including layover
Find flight
from$166
21:47 — 23:01
+1 day
21:47 — 23:25 G4407 Allegiant Air
Myrtle Beach — Covington
7h 50m stop
07:15 — 09:34 G4372 Allegiant Air
Covington — Punta Gorda
11h 2m stop
20:36 — 23:01 G42753 Allegiant Air
Punta Gorda — Pittsburgh
25h 14m
including layover
Find flight
from$146
*Departure and arrival times - local. Updated on July 19, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Myrtle Beach to Pittsburgh depends on and how to choose the most interesting flight option for you.

Distance between Myrtle Beach and Pittsburgh is 766 miles. Time difference between the cities is 0h. Airplanes depart 05:00 to 21:55 from 2 Myrtle Beach airports and arrive 05:00 to 21:55 to 3 Pittsburgh airports. Average flight time is 1h 30m.

  • The fastest flight 1h 28m
  • Average flight time 1h 30m
  • The earliest flight 05:00
  • The latest flight 21:55
  • Distance 476 ml

The cheapest months to travel to Pittsburgh are may (from 44 $), july (from 44 $), june (from 44 $).

The most expensive months are october (from 132 $), september (from 77 $), august (from 73 $).

What is the lowest airfare Myrtle Beach to Pittsburgh?

The cheapest plane ticket found by our users is $45. This airfare is for economy class on one-way NK2756 flight by Spirit Airlines for July 6, 2025 which leaves AFB in Myrtle Beach at 21:24 am and arrives at Pittsburgh Pittsburgh Int. at 22:52.

Economy class
$45
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Business class
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First class
?
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Popular Airlines on the Route

The flight Myrtle Beach — Pittsburgh is served by 5 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 1 departures per week at the price of from $ 171 . And the most expensive tickets are offered by United Airlines airline - from $ 1412.

Direct flights

There are 8 nonstop flights on the route. The fastest direct flight is NK2756 by Spirit Airlines takes 1h 28m and the cheapest is NK2756 by Spirit Airlines for $45.

  • NK - Spirit Airlines
    from $45
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  • G4 - Allegiant Air
    from $75
    Find
See more direct flights

Connecting Flights

There are 300 flights with layovers on the route. The fastest connecting flight is NK2650 by Spirit Airlines takes 4h 1m and the cheapest is NK2756 by Spirit Airlines for $91.

  • F9 - Frontier Airlines
    from $171
    Find
  • MX - Mexicana
    from $190
    Find
  • UA - United Airlines
    from $132
    Find
  • NK - Spirit Airlines
    from $91
    Find
  • G4 - Allegiant Air
    from $110
    Find
See more connecting flights

Airports

You can fly from Myrtle Beach to Pittsburgh from 2 airports (AFB, Grand Strand Airport).

Myrtle Beach airports

  • AFB-MYR
    from $45
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  • Grand Strand Airport-CRE
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Pittsburgh airports

  • Allegheny County-AGC
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  • Pittsburgh Int.-PIT
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  • Civic Ar Heli-CVA
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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