Cheap Flights from Myrtle Beach, SC to Pittsburgh, PA from $143
Return flight: Pittsburgh – Myrtle Beach
On Cheapflightsplus.com you will find 62 connecting flights from Myrtle Beach to Pittsburgh. You can compare airfare deals from 4 airlines and multiple travel sites from $143, book and save on cheap plane tickets and last minute offers. Also check out MYR-PIT flight schedule to find best flight time, convenient departure and arrival airports.
Find One-Way and Round-Trip Myrtle Beach to Pittsburgh Flight Deals
To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights».
To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight.
Cheapest flights in November: $143 (one-way), $245 (round-trip).
Direct flights
Check prices for return flight
Best Flights from Myrtle Beach to Pittsburgh Today
Take a look at the list of non stop flights and flights with layovers from Myrtle Beach to Pittsburgh with the lowest price of $143. Take a look at the list of flights with layovers from Myrtle Beach to Pittsburgh from $143. There’re no direct flights. The fastest connecting flight – 4h 50m.
| Price | Departure | Arrival | Flight Duration | Airline | Flight |
|---|---|---|---|---|---|
| from $143 | 19:43 Myrtle Beach AFB | 19:56+1 день Pittsburgh Pittsburgh Int. | 24h 13m layover 20h 30m - Sanford | Spirit Airlines | NK2362 G42742 |
| from $144 | 16:45 Myrtle Beach AFB | 23:44 Pittsburgh Pittsburgh Int. | 6h 59m layover 2h 53m - Chicago | United Airlines | UA444 UA3464 |
| from $186 | 14:40 Myrtle Beach AFB | 23:05 Pittsburgh Pittsburgh Int. | 8h 25m layover 4h 1m - Miami | Spirit Airlines | NK2356 NK2280 |
| from $207 | 13:15 Myrtle Beach AFB | 14:25+1 день Pittsburgh Pittsburgh Int. | 25h 10m layover 22h 8m - Philadelphia | Spirit Airlines | NK2391 F91791 |
| from $152 | 14:00 Myrtle Beach AFB | 19:56+1 день Pittsburgh Pittsburgh Int. | 29h 56m layover 4h 7m - Newark 18h 50m - Sanford | Spirit Airlines | NK2404 NK2819 G42742 |
| from $160 | 10:35 Myrtle Beach AFB | 17:04+1 день Pittsburgh Pittsburgh Int. | 30h 29m layover 22h 9m - New Haven 2h 24m - Nashville | Casino Express | XP492 XP624 G42727 |
| from $173 | 12:13 Myrtle Beach AFB | 19:56+1 день Pittsburgh Pittsburgh Int. | 31h 43m layover 20h 48m - Akron 4h 51m - Sanford | Mexicana | MX730 G41262 G42742 |
| from $189 | 08:00 Myrtle Beach AFB | 09:15+1 день Pittsburgh Pittsburgh Int. | 25h 15m layover 1h 2m - Atlantic City 18h 7m - Orlando | Spirit Airlines | NK2406 NK1973 NK412 |
| from $192 | 21:04 Myrtle Beach AFB | 17:05+1 день Pittsburgh Pittsburgh Int. | 20h 1m layover 11h 22m - Boston 0h 55m - Orlando | Spirit Airlines | NK2350 NK426 NK2446 |
| from $192 | 15:39 Myrtle Beach AFB | 17:05+1 день Pittsburgh Pittsburgh Int. | 25h 26m layover 16h 44m - Boston 0h 55m - Orlando | Spirit Airlines | NK2302 NK426 NK2446 |
| from $197 | 09:00 Myrtle Beach AFB | 09:15+1 день Pittsburgh Pittsburgh Int. | 24h 15m layover 3h 9m - Newark 14h 10m - Orlando | Spirit Airlines | NK2570 NK2440 NK412 |
| from $197 | 09:00 Myrtle Beach AFB | 17:05+1 день Pittsburgh Pittsburgh Int. | 32h 5m layover 3h 9m - Newark 21h 52m - Orlando | Spirit Airlines | NK2570 NK2440 NK2446 |
| from $199 | 20:40 Myrtle Beach AFB | 23:05+1 день Pittsburgh Pittsburgh Int. | 26h 25m layover 12h 37m - New York 6h 15m - Miami | Spirit Airlines | NK2399 NK2374 NK2280 |
| from $203 | 08:25 Myrtle Beach AFB | 08:44+1 день Pittsburgh Pittsburgh Int. | 24h 19m layover 5h 36m - Hartford 12h 49m - Charleston | Spirit Airlines | NK2661 MX500 MX210 |
| from $207 | 09:18 Myrtle Beach AFB | 19:56+1 день Pittsburgh Pittsburgh Int. | 34h 38m layover 5h 57m - New York 21h 45m - Sanford | Spirit Airlines | NK2352 NK719 G42742 |
| from $212 | 09:18 Myrtle Beach AFB | 09:15+1 день Pittsburgh Pittsburgh Int. | 23h 57m layover 5h 57m - New York 11h 3m - Orlando | Spirit Airlines | NK2352 NK719 NK412 |
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on August 17, 2025
Flight Schedule Myrtle Beach (South Carolina) to Pittsburgh (Pennsylvania)
Full flight schedule will help you in detecting at what time planes fly from Myrtle Beach to Pittsburgh. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
| Departure | Arrival | Flight Details | Flight Duration | Price |
|---|---|---|---|---|
|
12:47 — 23:40
|
12:47 — 14:40
UA661
United Airlines
Myrtle Beach — Newark
7h 20m stop
22:00 — 23:40
UA3477
United Airlines
Newark — Pittsburgh
|
10h 53m including layover |
Find flight
from$363 |
|
|
13:15 — 14:25
+1 day
|
13:15 — 14:56
NK2391
Spirit Airlines
Myrtle Beach — Philadelphia
22h 8m stop
13:04 — 14:25
F91791
Frontier Airlines
Philadelphia — Pittsburgh
|
25h 10m including layover |
Find flight
from$207 |
|
|
16:45 — 23:44
|
16:45 — 18:14
UA444
United Airlines
Myrtle Beach — Chicago
2h 53m stop
21:07 — 23:44
UA3464
United Airlines
Chicago — Pittsburgh
|
6h 59m including layover |
Find flight
from$144 |
|
|
16:45 — 10:01
+1 day
|
16:45 — 18:14
UA444
United Airlines
Myrtle Beach — Chicago
13h 10m stop
07:24 — 10:01
UA1285
United Airlines
Chicago — Pittsburgh
|
17h 16m including layover |
Find flight
from$612 |
|
|
18:11 — 23:40
|
18:11 — 20:15
UA3638
United Airlines
Myrtle Beach — Newark
1h 45m stop
22:00 — 23:40
UA3477
United Airlines
Newark — Pittsburgh
|
5h 29m including layover |
Find flight
from$264 |
|
|
18:11 — 10:35
+1 day
|
18:11 — 20:15
UA3638
United Airlines
Myrtle Beach — Newark
12h 45m stop
09:00 — 10:35
UA3501
United Airlines
Newark — Pittsburgh
|
16h 24m including layover |
Find flight
from$363 |
|
|
19:43 — 19:56
+1 day
|
19:43 — 21:12
NK2362
Spirit Airlines
Myrtle Beach — Sanford
20h 30m stop
17:42 — 19:56
G42742
Allegiant Air
Sanford — Pittsburgh
|
24h 13m including layover |
Find flight
from$143 |
|
|
19:43 — 09:15
+1 day
|
19:43 — 21:12
NK2362
Spirit Airlines
Myrtle Beach — Orlando
9h 48m stop
07:00 — 09:15
NK412
Spirit Airlines
Orlando — Pittsburgh
|
13h 32m including layover |
Find flight
from$148 |
|
|
08:00 — 09:15
+1 day
|
08:00 — 09:24
NK2406
Spirit Airlines
Myrtle Beach — Atlantic City
1h 2m stop
10:26 — 12:53
NK1973
Spirit Airlines
Atlantic City — Orlando
18h 7m stop
07:00 — 09:15
NK412
Spirit Airlines
Orlando — Pittsburgh
|
25h 15m including layover |
Find flight
from$189 |
|
|
08:25 — 08:44
+1 day
|
08:25 — 10:16
NK2661
Spirit Airlines
Myrtle Beach — Hartford
5h 36m stop
15:52 — 18:11
MX500
Mexicana
Hartford — Charleston
12h 49m stop
07:00 — 08:44
MX210
Mexicana
Charleston — Pittsburgh
|
24h 19m including layover |
Find flight
from$203 |
|
|
09:00 — 09:15
+1 day
|
09:00 — 10:51
NK2570
Spirit Airlines
Myrtle Beach — Newark
3h 9m stop
14:00 — 16:50
NK2440
Spirit Airlines
Newark — Orlando
14h 10m stop
07:00 — 09:15
NK412
Spirit Airlines
Orlando — Pittsburgh
|
24h 15m including layover |
Find flight
from$197 |
|
|
09:00 — 17:05
+1 day
|
09:00 — 10:51
NK2570
Spirit Airlines
Myrtle Beach — Newark
3h 9m stop
14:00 — 16:50
NK2440
Spirit Airlines
Newark — Orlando
21h 52m stop
14:42 — 17:05
NK2446
Spirit Airlines
Orlando — Pittsburgh
|
32h 5m including layover |
Find flight
from$197 |
|
|
10:35 — 17:04
+1 day
|
10:35 — 12:26
XP492
Casino Express
Myrtle Beach — New Haven
22h 9m stop
10:35 — 12:07
XP624
Casino Express
New Haven — Nashville
2h 24m stop
14:31 — 17:04
G42727
Allegiant Air
Nashville — Pittsburgh
|
30h 29m including layover |
Find flight
from$160 |
|
|
12:13 — 19:56
+1 day
|
12:13 — 13:50
MX730
Mexicana
Myrtle Beach — Akron
20h 48m stop
10:38 — 12:51
G41262
Allegiant Air
Akron — Sanford
4h 51m stop
17:42 — 19:56
G42742
Allegiant Air
Sanford — Pittsburgh
|
31h 43m including layover |
Find flight
from$173 |
|
|
13:15 — 19:56
+1 day
|
13:15 — 14:56
NK2391
Spirit Airlines
Myrtle Beach — Philadelphia
4h 13m stop
19:09 — 21:37
NK2508
Spirit Airlines
Philadelphia — Sanford
20h 5m stop
17:42 — 19:56
G42742
Allegiant Air
Sanford — Pittsburgh
|
30h 41m including layover |
Find flight
from$221 |
|
|
14:00 — 19:56
+1 day
|
14:00 — 15:53
NK2404
Spirit Airlines
Myrtle Beach — Newark
4h 7m stop
20:00 — 22:52
NK2819
Spirit Airlines
Newark — Sanford
18h 50m stop
17:42 — 19:56
G42742
Allegiant Air
Sanford — Pittsburgh
|
29h 56m including layover |
Find flight
from$152 |
|
|
14:00 — 09:15
+1 day
|
14:00 — 15:53
NK2404
Spirit Airlines
Myrtle Beach — Newark
4h 7m stop
20:00 — 22:52
NK2819
Spirit Airlines
Newark — Orlando
8h 8m stop
07:00 — 09:15
NK412
Spirit Airlines
Orlando — Pittsburgh
|
19h 15m including layover |
Find flight
from$157 |
|
|
15:39 — 17:05
+1 day
|
15:39 — 17:50
NK2302
Spirit Airlines
Myrtle Beach — Boston
16h 44m stop
10:34 — 13:47
NK426
Spirit Airlines
Boston — Orlando
55m stop
14:42 — 17:05
NK2446
Spirit Airlines
Orlando — Pittsburgh
|
25h 26m including layover |
Find flight
from$192 |
|
|
20:40 — 23:05
+1 day
|
20:40 — 22:22
NK2399
Spirit Airlines
Myrtle Beach — New York
12h 37m stop
10:59 — 14:10
NK2374
Spirit Airlines
New York — Miami
6h 15m stop
20:25 — 23:05
NK2280
Spirit Airlines
Miami — Pittsburgh
|
26h 25m including layover |
Find flight
from$199 |
|
|
20:40 — 17:05
+1 day
|
20:40 — 22:22
NK2399
Spirit Airlines
Myrtle Beach — New York
7h 33m stop
05:55 — 08:43
NK2364
Spirit Airlines
New York — Orlando
5h 59m stop
14:42 — 17:05
NK2446
Spirit Airlines
Orlando — Pittsburgh
|
20h 25m including layover |
Find flight
from$215 |
|
|
21:04 — 17:05
+1 day
|
21:04 — 23:12
NK2350
Spirit Airlines
Myrtle Beach — Boston
11h 22m stop
10:34 — 13:47
NK426
Spirit Airlines
Boston — Orlando
55m stop
14:42 — 17:05
NK2446
Spirit Airlines
Orlando — Pittsburgh
|
20h 1m including layover |
Find flight
from$192 |
|
*Departure and arrival times - local. Updated on August 17, 2025
Flight Information
Below we will explain in detail what the flights cost on the destination from Myrtle Beach to Pittsburgh depends on and how to choose the most interesting flight option for you.
Distance between Myrtle Beach and Pittsburgh is 766 miles. Time difference between the cities is 0h. Airplanes depart 08:00 to 21:04 from 2 Myrtle Beach airports and arrive 08:00 to 21:04 to 3 Pittsburgh airports. Average flight time is 22h 11m.
- The fastest flight 4h 50m
- Average flight time 22h 11m
- The earliest flight 08:00
- The latest flight 21:04
- Distance 476 ml
The cheapest months to travel to Pittsburgh are august (from 143 $).
What is the lowest airfare Myrtle Beach to Pittsburgh?
The cheapest plane ticket found by our users is $143. This airfare is for economy class on one-way NK2362 flight by Spirit Airlines for August 20, 2025 which leaves AFB in Myrtle Beach at 19:43 am and arrives at Pittsburgh Pittsburgh Int. at 19:56.
Economy class
$143
Business class
?
First class
?
Popular Airlines on the Route
The flight Myrtle Beach — Pittsburgh is served by 4 regular airlines and 1 low-cost airline. Most of the flights on this route are operated by Casino Express - 1 departures per week at the price of from $ 160 . And the most expensive tickets are offered by United Airlines airline - from $ 612.
Direct flights
There’re no direct flights on this route. Try flights with stops.
Connecting Flights
There are 62 flights with layovers on the route. The fastest connecting flight is UA661 by United Airlines takes 4h 50m and the cheapest is NK2362 by Spirit Airlines for $143.
- XP - Casino Expressfrom $160Find
- MX - Mexicanafrom $173Find
- UA - United Airlinesfrom $144Find
- NK - Spirit Airlinesfrom $143Find
See more connecting flights
Airports
You can fly from Myrtle Beach to Pittsburgh from 2 airports (AFB, Grand Strand Airport).
Myrtle Beach airports
- AFB-MYRfrom $143Find
- Grand Strand Airport-CREFind
Pittsburgh airports
- Allegheny County-AGCFind
- Pittsburgh Int.-PITFind
- Civic Ar Heli-CVAFind
Airplanes
There are flights to Pittsburgh from Myrtle Beach by 4 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Myrtle Beach
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Top International Destinations from Myrtle Beach
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
- from $57Find
How to book a plane ticket yourself?
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