Cheap Flights from Myrtle Beach, SC to Tampa, FL from $51

Return flight: Tampa – Myrtle Beach

On Cheapflightsplus.com you will find 1 direct and 163 connecting flights from Myrtle Beach to Tampa. You can compare airfare deals from 5 airlines and multiple travel sites from $51, book and save on cheap plane tickets and last minute offers. Also check out MYR-TPA flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Myrtle Beach to Tampa depends on and how to choose the most interesting flight option for you.

Distance between Myrtle Beach and Tampa is 722 miles. Time difference between the cities is 0h. Airplanes depart 05:00 to 22:32 from 2 Myrtle Beach airports and arrive 05:00 to 22:32 to 4 Tampa airports. Average flight time is 1h 37m.

  • The fastest flight 1h 37m
  • Average flight time 1h 37m
  • The earliest flight 05:00
  • The latest flight 22:32
  • Distance 449 ml

The cheapest months to travel to Tampa are august (from 51 $), july (from 71 $), october (from 136 $).

The most expensive months are february (from 1 009 $), september (from 136 $), october (from 136 $).

What is the lowest airfare Myrtle Beach to Tampa?

The cheapest plane ticket found by our users is $51. This airfare is for economy class on one-way MX173 flight by Mexicana for July 6, 2025 which leaves AFB in Myrtle Beach at 13:40 am and arrives at Tampa Tampa Int. at 15:17.

Economy class
$51
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Business class
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First class
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Flight Schedule Myrtle Beach (South Carolina) to Tampa (Florida)

05:00 — 16:10
11h 10m flight time
Find flight
from$136
05:00 — 06:52 Myrtle Beach — Miami
NK3646 Spirit Airlines
8h 13m stop
15:05 — 16:10 Miami — Tampa
NK322 Spirit Airlines
05:00 — 23:06
18h 6m flight time
Find flight
from$136
05:00 — 06:52 Myrtle Beach — Miami
NK3646 Spirit Airlines
15h 7m stop
21:59 — 23:06 Miami — Tampa
NK1954 Spirit Airlines
06:14 — 09:27
3h 13m flight time
Find flight
from$133
06:14 — 08:05 Myrtle Beach — Miami
NK1491 Spirit Airlines
31m stop
08:36 — 09:27 Miami — Tampa
NK1757 Spirit Airlines
10:40 — 18:50
8h 10m flight time
Find flight
from$99
10:40 — 12:20 Myrtle Beach — Philadelphia
F93272 Frontier Airlines
3h 35m stop
15:55 — 18:50 Philadelphia — Tampa
F92339 Frontier Airlines
10:57 — 17:09
6h 12m flight time
Find flight
from$113
10:57 — 12:29 Myrtle Beach — Louisville
NK2750 Spirit Airlines
2h 38m stop
15:07 — 17:09 Louisville — Tampa
NK2159 Spirit Airlines
10:58 — 18:29
7h 31m flight time
Find flight
from$151
10:58 — 13:04 Myrtle Beach — Newark
UA2630 United Airlines
2h 25m stop
15:29 — 18:29 Newark — Tampa
UA2301 United Airlines
12:18 — 21:31
9h 13m flight time
Find flight
from$121
12:18 — 14:12 Myrtle Beach — Detroit
NK3184 Spirit Airlines
4h 44m stop
18:56 — 21:31 Detroit — Tampa
NK2083 Spirit Airlines
12:37 — 08:21+1day
19h 44m flight time
Find flight
from$155
12:37 — 13:52 Myrtle Beach — Huntington
G42598 Allegiant Air
6h 4m stop
19:56 — 22:18 Huntington — Miami
G43471 Allegiant Air
9h 12m stop
07:30 — 08:21 Miami — Tampa
NK2578 Spirit Airlines
12:37 — 19:27+1day
30h 50m flight time
Find flight
from$155
12:37 — 13:52 Myrtle Beach — Huntington
G42598 Allegiant Air
6h 4m stop
19:56 — 22:18 Huntington — Miami
G43471 Allegiant Air
20h 10m stop
18:28 — 19:27 Miami — Tampa
NK2233 Spirit Airlines
13:40 — 15:17
1h 37m flight time
Find flight
from$51
Myrtle Beach — Tampa
MX173 Mexicana
14:47 — 20:16
5h 29m flight time
Find flight
from$151
14:47 — 16:21 Myrtle Beach — Washington D.C.
UA6194 United Airlines
1h 19m stop
17:40 — 20:16 Washington D.C. — Tampa
UA1140 United Airlines
15:16 — 00:19+1day
9h 3m flight time
Find flight
from$152
15:16 — 16:41 Myrtle Beach — Chicago
NK1815 Spirit Airlines
3h 48m stop
20:29 — 00:19 Chicago — Tampa
NK1763 Spirit Airlines
19:13 — 21:30+1day
26h 17m flight time
Find flight
from$150
19:13 — 21:10 Myrtle Beach — Newark
NK1809 Spirit Airlines
16h 49m stop
13:59 — 15:59 Newark — Charlotte
NK1384 Spirit Airlines
3h 48m stop
19:47 — 21:30 Charlotte — Tampa
NK1295 Spirit Airlines
20:57 — 08:25+1day
11h 28m flight time
Find flight
from$122
20:57 — 23:01 Myrtle Beach — Detroit
NK1007 Spirit Airlines
6h 44m stop
05:45 — 08:25 Detroit — Tampa
NK1235 Spirit Airlines
22:32 — 08:03+1day
9h 31m flight time
Find flight
from$104
22:32 — 00:12 Myrtle Beach — Philadelphia
F94948 Frontier Airlines
5h 13m stop
05:25 — 08:03 Philadelphia — Tampa
F91473 Frontier Airlines
Full flight schedule will help you in detecting at what time planes fly from Myrtle Beach to Tampa. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on September 28, 2025.

Popular Airlines on the Route

The flight Myrtle Beach — Tampa is served by 5 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 2 departures per week at the price of from $ 99 . And the most expensive tickets are offered by United Airlines airline - from $ 1912.

Direct flights

There are 1 nonstop flights on the route. The fastest direct flight is MX173 by Mexicana takes 1h 37m and the cheapest is MX173 by Mexicana for $51.

  • MX - Mexicana
    from $51
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See more direct flights

Connecting Flights

There are 163 flights with layovers on the route. The fastest connecting flight is NK1491 by Spirit Airlines takes 3h 13m and the cheapest is MX173 by Mexicana for $99.

  • F9 - Frontier Airlines
    from $99
    Find
  • MX - Mexicana
    from $214
    Find
  • UA - United Airlines
    from $151
    Find
  • NK - Spirit Airlines
    from $113
    Find
  • G4 - Allegiant Air
    from $155
    Find
See more connecting flights

Airports

You can fly from Myrtle Beach to Tampa from 2 airports (AFB, Grand Strand Airport).

Myrtle Beach airports

  • AFB-MYR
    from $51
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  • Grand Strand Airport-CRE
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Tampa airports

  • Topp Of Tampa-KYO
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  • Mac Dill AFB-MCF
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  • Peter O'Knight-TPF
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  • Tampa Int.-TPA
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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