Cheap Flights from Chicago, IL to Myrtle Beach, SC from $52

On Cheapflightsplus.com you will find 10 direct and 520 connecting flights from Chicago to Myrtle Beach. You can compare airfare deals from 5 airlines and multiple travel sites from $52, book and save on cheap plane tickets and last minute offers. Also check out CHI-MYR flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Chicago to Myrtle Beach depends on and how to choose the most interesting flight option for you.

Distance between Chicago and Myrtle Beach is 1189 miles. Time difference between the cities is 1h. Airplanes depart 05:00 to 21:45 from 7 Chicago airports and arrive 05:00 to 21:45 to 2 Myrtle Beach airports. Average flight time is 2h 13m.

  • The fastest flight 1h 58m
  • Average flight time 2h 13m
  • The earliest flight 05:00
  • The latest flight 21:45
  • Distance 739 ml

The cheapest months to travel to Myrtle Beach are may (from 52 $), june (from 62 $), august (from 62 $).

The most expensive months are september (from 103 $), october (from 103 $), july (from 72 $).

What is the lowest airfare Chicago to Myrtle Beach?

The cheapest plane ticket found by our users is $52. This airfare is for economy class on one-way NK2521 flight by Spirit Airlines for June 6, 2025 which leaves O'Hare International in Chicago at 14:19 am and arrives at Myrtle Beach AFB at 17:17.

Economy class
$52
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Business class
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First class
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Flight Schedule Chicago (Illinois) to Myrtle Beach (South Carolina)

05:51 — 12:50
5h 59m flight time
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from$89
05:51 — 09:00 Chicago — New York
NK2175 Spirit Airlines
1h 55m stop
10:55 — 12:50 New York — Myrtle Beach
NK2472 Spirit Airlines
07:10 — 10:26
2h 16m flight time
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from$126
Chicago — Myrtle Beach
UA1413 United Airlines
07:10 — 10:26
2h 16m flight time
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from$151
Chicago — Myrtle Beach
UA788 United Airlines
07:12 — 10:37
2h 25m flight time
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from$211
Chicago — Myrtle Beach
UA3640 United Airlines
07:56 — 19:22
10h 26m flight time
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from$89
07:47 — 11:26 Chicago — Orlando
NK2550 Spirit Airlines
6h 14m stop
17:55 — 19:25 Orlando — Myrtle Beach
NK2088 Spirit Airlines
11:11 — 14:11
2h flight time
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from$62
Chicago — Myrtle Beach
NK1819 Spirit Airlines
11:20 — 14:42
2h 22m flight time
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from$138
Chicago — Myrtle Beach
UA5541 United Airlines
11:20 — 14:35
2h 15m flight time
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from$139
Chicago — Myrtle Beach
UA1377 United Airlines
11:20 — 14:31
2h 11m flight time
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from$197
Chicago — Myrtle Beach
UA1277 United Airlines
12:41 — 21:05
7h 24m flight time
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from$84
09:55 — 14:02 Chicago — Miami
NK2187 Spirit Airlines
2h 36m stop
19:20 — 21:05 Miami — Myrtle Beach
NK2657 Spirit Airlines
14:19 — 17:17
1h 58m flight time
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from$52
Chicago — Myrtle Beach
NK2521 Spirit Airlines
15:29 — 22:54
6h 25m flight time
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from$94
15:29 — 19:39 Chicago — Miami
NK867 Spirit Airlines
1h 32m stop
21:11 — 22:54 Miami — Myrtle Beach
NK3647 Spirit Airlines
15:36 — 21:01
4h 25m flight time
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from$94
15:36 — 17:05 Chicago — Nashville
NK1184 Spirit Airlines
1h 30m stop
18:35 — 21:01 Nashville — Myrtle Beach
NK1493 Spirit Airlines
16:12 — 19:19
2h 7m flight time
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from$140
Chicago — Myrtle Beach
NK3034 Spirit Airlines
20:14 — 23:23
2h 9m flight time
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from$62
Chicago — Myrtle Beach
NK3191 Spirit Airlines
Full flight schedule will help you in detecting at what time planes fly from Chicago to Myrtle Beach. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on October 19, 2025.

Popular Airlines on the Route

The flight Chicago — Myrtle Beach is served by 5 regular airlines and 4 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 1 departures per week at the price of from $ 157 . And the most expensive tickets are offered by United Airlines airline - from $ 914.

Direct flights

There are 10 nonstop flights on the route. The fastest direct flight is NK2521 by Spirit Airlines takes 1h 58m and the cheapest is NK2521 by Spirit Airlines for $52.

  • UA - United Airlines
    from $126
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  • NK - Spirit Airlines
    from $52
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Connecting Flights

There are 520 flights with layovers on the route. The fastest connecting flight is UA1068 by United Airlines takes 4h 14m and the cheapest is NK2521 by Spirit Airlines for $84.

  • F9 - Frontier Airlines
    from $157
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  • SY - Sun Country Airlines
    from $180
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  • UA - United Airlines
    from $207
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  • NK - Spirit Airlines
    from $84
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  • G4 - Allegiant Air
    from $149
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Airports

You can fly from Chicago to Myrtle Beach from 7 airports (O'Hare International, Midway, Dupage County, Chicago FSS, Merrill C Meigs (closed), Pal-Waukee, Chicago NAS).

Chicago airports

  • O'Hare International-ORD
    from $52
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  • Midway-MDW
    from $149
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  • Dupage County-DPA
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  • Chicago FSS-CHI
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  • Merrill C Meigs (closed)-CGX
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  • Pal-Waukee-PWK
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  • Chicago NAS-NOH
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Myrtle Beach airports

  • AFB-MYR
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  • Grand Strand Airport-CRE
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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