Cheap Flights from Knoxville, TN to New Orleans, LA from $132

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On Cheapflightsplus.com you will find 528 connecting flights from Knoxville to New Orleans. You can compare airfare deals from 2 airlines and multiple travel sites from $132, book and save on cheap plane tickets and last minute offers. Also check out TYS-MSY flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Knoxville to New Orleans Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $132 (one-way), $226 (round-trip).

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Best Flights from Knoxville to New Orleans Today

Take a look at the list of non stop flights and flights with layovers from Knoxville to New Orleans with the lowest price of $132. Take a look at the list of flights with layovers from Knoxville to New Orleans from $132. There’re no direct flights. The fastest connecting flight – 4h 29m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $88 Find flight	12:45 Knoxville Mc Ghee Tyson	00:30+1 день New Orleans Louis Armstrong Intl	12h 45m layover 8h 23m - Baltimore	Allegiant Air	G41397 NK2286
from $108 Find flight	10:54 Knoxville Mc Ghee Tyson	06:58+1 день New Orleans Louis Armstrong Intl	21h 4m layover 17h 2m - Miami	Allegiant Air	G4494 NK1052
from $120 Find flight	12:45 Knoxville Mc Ghee Tyson	19:10+1 день New Orleans Louis Armstrong Intl	31h 25m layover 21h 31m - Baltimore 3h 35m - Miami	Allegiant Air	G41397 NK2901 NK1999
from $141 Find flight	15:34 Knoxville Mc Ghee Tyson	07:02+1 день New Orleans Louis Armstrong Intl	16h 28m layover 4h 10m - Miami 7h 15m - Orlando	Allegiant Air	G4488 NK676 NK423

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 14, 2025

Flight Schedule Knoxville (Tennessee) to New Orleans (Louisiana)

Full flight schedule will help you in detecting at what time planes fly from Knoxville to New Orleans. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
06:00 — 11:43	06:00 — 07:37 G43063 Allegiant Air Knoxville — Orlando 3h 18m stop 10:55 — 11:43 NK1572 Spirit Airlines Orlando — New Orleans	6h 43m including layover	Find flight from$122
06:00 — 20:05	06:00 — 07:34 G41439 Allegiant Air Knoxville — Orlando 11h 40m stop 19:14 — 20:05 NK2557 Spirit Airlines Orlando — New Orleans	15h 5m including layover	Find flight from$128
06:00 — 18:30	06:00 — 07:40 G43030 Allegiant Air Knoxville — Orlando 9h 59m stop 17:39 — 18:30 NK2084 Spirit Airlines Orlando — New Orleans	13h 30m including layover	Find flight from$136
06:00 — 07:02 +1 day	06:00 — 07:40 G43030 Allegiant Air Knoxville — Orlando 22h 35m stop 06:15 — 07:02 NK423 Spirit Airlines Orlando — New Orleans	26h 2m including layover	Find flight from$136
08:10 — 21:12	08:10 — 10:05 G43063 Allegiant Air Knoxville — Newark 8h 54m stop 18:59 — 21:12 NK2284 Spirit Airlines Newark — New Orleans	14h 2m including layover	Find flight from$130
10:54 — 06:58 +1 day	10:54 — 12:58 G4494 Allegiant Air Knoxville — Miami 17h 2m stop 06:00 — 06:58 NK1052 Spirit Airlines Miami — New Orleans	21h 4m including layover	Find flight from$108
10:54 — 12:49 +1 day	10:54 — 12:58 G4494 Allegiant Air Knoxville — Miami 22h 48m stop 11:46 — 12:49 NK1054 Spirit Airlines Miami — New Orleans	26h 55m including layover	Find flight from$134
11:23 — 06:58 +1 day	11:08 — 13:12 G4502 Allegiant Air Knoxville — Miami 16h 37m stop 06:00 — 06:58 NK1052 Spirit Airlines Miami — New Orleans	20h 35m including layover	Find flight from$132
11:23 — 12:49 +1 day	11:08 — 13:12 G4502 Allegiant Air Knoxville — Miami 22h 23m stop 11:46 — 12:49 NK1054 Spirit Airlines Miami — New Orleans	26h 26m including layover	Find flight from$132
12:45 — 00:30 +1 day	12:45 — 14:23 G41397 Allegiant Air Knoxville — Baltimore 8h 23m stop 22:46 — 00:30 NK2286 Spirit Airlines Baltimore — New Orleans	12h 45m including layover	Find flight from$88
15:34 — 06:58 +1 day	15:34 — 17:38 G4488 Allegiant Air Knoxville — Miami 12h 22m stop 06:00 — 06:58 NK1052 Spirit Airlines Miami — New Orleans	16h 24m including layover	Find flight from$109
15:34 — 12:49 +1 day	15:34 — 17:38 G4488 Allegiant Air Knoxville — Miami 18h 8m stop 11:46 — 12:49 NK1054 Spirit Airlines Miami — New Orleans	22h 15m including layover	Find flight from$113
17:02 — 07:02 +1 day	17:02 — 18:13 G41437 Allegiant Air Knoxville — Houston 11h 47m stop 06:00 — 07:02 NK1429 Spirit Airlines Houston — New Orleans	15h including layover	Find flight from$92
21:30 — 08:10 +1 day	21:30 — 23:29 G42152 Allegiant Air Knoxville — Miami 7h 36m stop 07:05 — 08:10 NK2204 Spirit Airlines Miami — New Orleans	11h 40m including layover	Find flight from$128
21:34 — 19:10 +1 day	21:34 — 23:34 G42120 Allegiant Air Knoxville — Miami 18h 31m stop 18:05 — 19:10 NK1999 Spirit Airlines Miami — New Orleans	22h 36m including layover	Find flight from$135

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on September 14, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Knoxville to New Orleans depends on and how to choose the most interesting flight option for you.

Distance between Knoxville and New Orleans is 872 miles. Time difference between the cities is 1h. Airplanes depart 05:45 to 21:34 from 1 Knoxville airport and arrive 05:45 to 21:34 to 3 New Orleans airports. Average flight time is 22h 24m.

The fastest flight 4h 29m
Average flight time 22h 24m
The earliest flight 05:45
The latest flight 21:34
Distance 542 ml

Popular Airlines on the Route

The flight Knoxville — New Orleans is served by 2 regular airlines and 1 low-cost airline. Most of the flights on this route are operated by United Airlines - 124 departures per week at the price of from $ 140 . And the most expensive tickets are offered by United Airlines airline - from $ 609.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 528 flights with layovers on the route. The fastest connecting flight is UA4913 by United Airlines takes 4h 29m.

UA - United Airlines

from $140

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G4 - Allegiant Air

from $88

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Airports

You can fly from Knoxville to New Orleans from 1 airports (Mc Ghee Tyson).

Knoxville airports

Mc Ghee Tyson-TYS

from $88
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New Orleans airports

Lakefront-NEW

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Louis Armstrong Intl-MSY

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Alvin Callendar-NBG

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Airplanes

There are flights to New Orleans from Knoxville by 2 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Knoxville

You may also consider searching for discounted plane tickets to some other popular places from Knoxville within United States.

Knoxville — Orlando

from $73

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Knoxville — Las Vegas

from $74

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Knoxville — Chicago

from $76

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Knoxville — Denver

from $74

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Knoxville — Miami

from $66

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Knoxville — Boston

from $69

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Knoxville — Houston

from $54

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Knoxville — New Orleans

from $56

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Knoxville — Tampa

from $80

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Knoxville — Austin

from $54

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Top International Destinations from Knoxville

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Knoxville — Cancun

from $69

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Knoxville — Panama City

from $61

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How to book a plane ticket yourself?

Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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