Cheap Flights from Knoxville, TN to Chicago, IL from $47

Return flight: Chicago – Knoxville
Page navigation
Price Calendar Cheap Flights Flights Schedule

On Cheapflightsplus.com you will find 13 direct and 554 connecting flights from Knoxville to Chicago. You can compare airfare deals from 3 airlines and multiple travel sites from $47, book and save on cheap plane tickets and last minute offers. Also check out TYS-CHI flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Knoxville to Chicago Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $47 (one-way), $81 (round-trip).
Direct flights
  • Check to choose departure date Check to choose departure date
Check prices for return flight
Find flights

Best Flights from Knoxville to Chicago Today

Take a look at the list of non stop flights and flights with layovers from Knoxville to Chicago with the lowest price of $47. The fastest direct flight takes 1h 33m and the fastest connecting – 4h 50m.
Price Departure Arrival Flight Duration Airline Flight
from $47
Find flight
13:31
Knoxville
Mc Ghee Tyson
 14:04
Chicago
Midway
 1h 33m Allegiant Air
G43026
from $62
Find flight
13:31
Knoxville
Mc Ghee Tyson
 14:04
Chicago
Midway
 1h 33m Allegiant Air
G43027
from $245
Find flight
07:00
Knoxville
Mc Ghee Tyson
 07:55
Chicago
O'Hare International
 1h 55m United Airlines
UA1562
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 15, 2025
Full flight schedule will help you in detecting at what time planes fly from Knoxville to Chicago. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
07:00 — 07:55
07:00 — 07:55 UA1562 United Airlines
Knoxville — Chicago
1h 55m
Find flight
from$245
07:00 — 07:57
07:00 — 07:57 UA1594 United Airlines
Knoxville — Chicago
1h 57m
Find flight
from$246
08:00 — 08:22
+1 day
08:00 — 08:21 G41398 Allegiant Air
Knoxville — Fort Walton Beach
21h 39m stop
06:00 — 08:22 G41455 Allegiant Air
Fort Walton Beach — Chicago
25h 22m
including layover
Find flight
from$97
10:55 — 11:58
10:55 — 11:58 UA5921 United Airlines
Knoxville — Chicago
2h 3m
Find flight
from$246
11:01 — 17:15
11:01 — 12:19 G41414 Allegiant Air
Knoxville — Minneapolis
3h 17m stop
15:36 — 17:15 SY259 Sun Country Airlines
Minneapolis — Chicago
7h 14m
including layover
Find flight
from$103
11:01 — 12:28
+1 day
11:01 — 12:19 G41414 Allegiant Air
Knoxville — Minneapolis
22h 31m stop
10:50 — 12:28 SY1629 Sun Country Airlines
Minneapolis — Chicago
26h 27m
including layover
Find flight
from$103
12:45 — 23:29
+1 day
12:45 — 14:23 G41397 Allegiant Air
Knoxville — Baltimore
22h 28m stop
12:51 — 15:14 NK1961 Spirit Airlines
Baltimore — Orlando
6h 11m stop
21:25 — 23:29 NK2190 Spirit Airlines
Orlando — Chicago
35h 44m
including layover
Find flight
from$99
13:29 — 14:03
13:29 — 14:03 G43062 Allegiant Air
Knoxville — Chicago
1h 34m
Find flight
from$47
13:31 — 14:04
13:31 — 14:04 G43026 Allegiant Air
Knoxville — Chicago
1h 33m
Find flight
from$47
13:31 — 14:04
13:31 — 14:04 G43027 Allegiant Air
Knoxville — Chicago
1h 33m
Find flight
from$62
13:56 — 14:55
13:56 — 14:55 UA5844 United Airlines
Knoxville — Chicago
1h 59m
Find flight
from$246
13:58 — 14:59
13:58 — 14:59 UA4388 United Airlines
Knoxville — Chicago
2h 1m
Find flight
from$246
14:00 — 15:02
14:00 — 15:02 UA4513 United Airlines
Knoxville — Chicago
2h 2m
Find flight
from$245
17:25 — 23:43
17:30 — 19:01 F94369 Frontier Airlines
Knoxville — Denver
1h 17m stop
20:22 — 23:52 F93174 Frontier Airlines
Denver — Chicago
7h 18m
including layover
Find flight
from$96
17:35 — 18:37
17:35 — 18:37 UA5767 United Airlines
Knoxville — Chicago
2h 2m
Find flight
from$245
*Departure and arrival times - local. Updated on September 15, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Knoxville to Chicago depends on and how to choose the most interesting flight option for you.

Distance between Knoxville and Chicago is 745 miles. Time difference between the cities is 1h. Airplanes depart 05:45 to 21:34 from 1 Knoxville airport and arrive 05:45 to 21:34 to 7 Chicago airports. Average flight time is 2h 1m.

  • The fastest flight 1h 33m
  • Average flight time 2h 1m
  • The earliest flight 05:45
  • The latest flight 21:34
  • Distance 463 ml

The cheapest months to travel to Chicago are july (from 47 $), june (from 47 $), may (from 51 $).

The most expensive months are november (from 547 $), december (from 417 $), february (from 147 $).

What is the lowest airfare Knoxville to Chicago?

The cheapest plane ticket found by our users is $47. This airfare is for economy class on one-way G43026 flight by Allegiant Air for July 4, 2025 which leaves Mc Ghee Tyson in Knoxville at 13:31 am and arrives at Chicago Midway at 14:04.

Economy class
$47
Find
Business class
?
Find
First class
?
Find

Popular Airlines on the Route

The flight Knoxville — Chicago is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 3 departures per week at the price of from $ 96 . And the most expensive tickets are offered by United Airlines airline - from $ 781.

Direct flights

There are 13 nonstop flights on the route. The fastest direct flight is G43026 by Allegiant Air takes 1h 33m and the cheapest is G43026 by Allegiant Air for $47.

  • UA - United Airlines
    from $245
    Find
  • G4 - Allegiant Air
    from $47
    Find
See more direct flights

Connecting Flights

There are 554 flights with layovers on the route. The fastest connecting flight is UA4324 by United Airlines takes 4h 50m and the cheapest is G43026 by Allegiant Air for $96.

  • F9 - Frontier Airlines
    from $96
    Find
  • UA - United Airlines
    from $147
    Find
  • G4 - Allegiant Air
    from $97
    Find
See more connecting flights

Airports

You can fly from Knoxville to Chicago from 1 airports (Mc Ghee Tyson).

Knoxville airports

  • Mc Ghee Tyson-TYS
    from $47
    Find

Chicago airports

  • O'Hare International-ORD
    Find
  • Midway-MDW
    Find
  • Dupage County-DPA
    Find
  • Chicago FSS-CHI
    Find
  • Merrill C Meigs (closed)-CGX
    Find
  • Pal-Waukee-PWK
    Find
  • Chicago NAS-NOH
    Find

Airplanes

There are flights to Chicago from Knoxville by 3 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Knoxville

You may also consider searching for discounted plane tickets to some other popular places from Knoxville within United States.

Top International Destinations from Knoxville

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back