Cheap Flights from Knoxville, TN to Chicago, IL from $81

One way Round trip

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On Cheapflightsplus.com you will find 7 direct and 84 connecting flights from Knoxville to Chicago. You can compare airfare deals from 3 airlines and multiple travel sites from $81, book and save on cheap plane tickets and last minute offers. Also check out TYS-CHI flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Knoxville to Chicago Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $81 (one-way), $139 (round-trip).

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Best Flights from Knoxville to Chicago Today

Take a look at the list of non stop flights and flights with layovers from Knoxville to Chicago with the lowest price of $81. The fastest direct flight takes 1h 55m and the fastest connecting – 4h 59m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $117 Find flight	13:55 Knoxville Mc Ghee Tyson	14:51 Chicago O'Hare International	1h 56m	United Airlines	UA5844
from $117 Find flight	07:00 Knoxville Mc Ghee Tyson	08:02 Chicago O'Hare International	2h 2m	United Airlines	UA1677
from $117 Find flight	17:35 Knoxville Mc Ghee Tyson	18:37 Chicago O'Hare International	2h 2m	United Airlines	UA5305
from $161 Find flight	07:00 Knoxville Mc Ghee Tyson	08:03 Chicago O'Hare International	2h 3m	United Airlines	UA2046
from $258 Find flight	06:55 Knoxville Mc Ghee Tyson	08:00 Chicago O'Hare International	2h 5m	United Airlines	UA5281
from $301 Find flight	10:45 Knoxville Mc Ghee Tyson	11:52 Chicago O'Hare International	2h 7m	United Airlines	UA5843
from $81 Find flight	16:19 Knoxville Mc Ghee Tyson	00:48+1 день Chicago O'Hare International	9h 29m layover 3h 24m - Denver	Frontier Airlines	F94369 F93174
from $127 Find flight	05:45 Knoxville Mc Ghee Tyson	09:44 Chicago O'Hare International	4h 59m layover 0h 54m - Washington D.C.	United Airlines	UA4311 UA2440
from $127 Find flight	14:35 Knoxville Mc Ghee Tyson	18:55 Chicago O'Hare International	5h 20m layover 1h 16m - Washington D.C.	United Airlines	UA4848 UA1117
from $127 Find flight	09:35 Knoxville Mc Ghee Tyson	14:34 Chicago O'Hare International	5h 59m layover 1h 54m - Washington D.C.	United Airlines	UA4325 UA1193
from $139 Find flight	12:25 Knoxville Mc Ghee Tyson	22:29 Chicago O'Hare International	11h 4m layover 6h 24m - Tampa	Allegiant Air	G43049 NK1171
from $139 Find flight	08:30 Knoxville Mc Ghee Tyson	18:57 Chicago O'Hare International	11h 27m layover 6h 29m - Tampa	Allegiant Air	G43051 NK572
from $149 Find flight	11:00 Knoxville Mc Ghee Tyson	20:13 Chicago O'Hare International	10h 13m layover 4h 33m - Miami	Allegiant Air	G41415 NK19
from $160 Find flight	14:03 Knoxville Mc Ghee Tyson	22:51 Chicago O'Hare International	9h 48m layover 4h 10m - Miami	Allegiant Air	G41431 NK718
from $164 Find flight	14:03 Knoxville Mc Ghee Tyson	20:13 Chicago O'Hare International	7h 10m layover 1h 30m - Miami	Allegiant Air	G41431 NK19
from $173 Find flight	11:00 Knoxville Mc Ghee Tyson	22:55 Chicago O'Hare International	12h 55m layover 2h 50m - Miami 2h 15m - New York	Allegiant Air	G41415 NK220 NK225

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on December 21, 2024

Flight Schedule Knoxville (Tennessee) to Chicago (Illinois)

Full flight schedule will help you in detecting at what time planes fly from Knoxville to Chicago. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
06:55 — 08:00	06:55 — 08:00 UA5281 United Airlines Knoxville — Chicago	2h 5m	Find flight from$258
07:00 — 08:02	07:00 — 08:02 UA1677 United Airlines Knoxville — Chicago	2h 2m	Find flight from$117
07:00 — 08:03	07:00 — 08:03 UA2046 United Airlines Knoxville — Chicago	2h 3m	Find flight from$161
10:45 — 11:52	10:45 — 11:52 UA5843 United Airlines Knoxville — Chicago	2h 7m	Find flight from$301
13:55 — 14:51	13:55 — 14:51 UA5844 United Airlines Knoxville — Chicago	1h 56m	Find flight from$117
14:00 — 14:55	14:00 — 14:55 UA4408 United Airlines Knoxville — Chicago	1h 55m	Find flight from$262
17:35 — 18:37	17:35 — 18:37 UA5305 United Airlines Knoxville — Chicago	2h 2m	Find flight from$117
05:45 — 09:44	05:45 — 07:31 UA4311 United Airlines Knoxville — Washington D.C. 54m stop 08:25 — 09:44 UA2440 United Airlines Washington D.C. — Chicago	4h 59m including layover	Find flight from$127
05:45 — 09:55	05:45 — 07:29 UA4311 United Airlines Knoxville — Washington D.C. 1h 6m stop 08:35 — 09:55 UA1710 United Airlines Washington D.C. — Chicago	5h 10m including layover	Find flight from$268
08:30 — 18:57	08:30 — 10:21 G43051 Allegiant Air Knoxville — Tampa 6h 29m stop 16:50 — 18:57 NK572 Spirit Airlines Tampa — Chicago	11h 27m including layover	Find flight from$139
09:00 — 16:08	09:00 — 10:44 G43032 Allegiant Air Knoxville — Orlando 3h 13m stop 13:57 — 16:08 NK223 Spirit Airlines Orlando — Chicago	8h 8m including layover	Find flight from$220
09:35 — 14:34	09:35 — 11:21 UA4325 United Airlines Knoxville — Washington D.C. 1h 54m stop 13:15 — 14:34 UA1193 United Airlines Washington D.C. — Chicago	5h 59m including layover	Find flight from$127
11:00 — 20:13	11:00 — 13:17 G41415 Allegiant Air Knoxville — Miami 4h 33m stop 17:50 — 20:13 NK19 Spirit Airlines Miami — Chicago	10h 13m including layover	Find flight from$149
12:25 — 22:29	12:25 — 14:08 G43049 Allegiant Air Knoxville — Tampa 6h 24m stop 20:32 — 22:29 NK1171 Spirit Airlines Tampa — Chicago	11h 4m including layover	Find flight from$139
12:27 — 19:51	12:27 — 14:39 G43056 Allegiant Air Knoxville — Miami 2h 47m stop 17:26 — 19:51 NK7 Spirit Airlines Miami — Chicago	8h 24m including layover	Find flight from$325
13:41 — 22:51	13:41 — 15:58 G41416 Allegiant Air Knoxville — Miami 4h 32m stop 20:30 — 22:51 NK718 Spirit Airlines Miami — Chicago	10h 10m including layover	Find flight from$204
14:03 — 22:51	14:03 — 16:20 G41431 Allegiant Air Knoxville — Miami 4h 10m stop 20:30 — 22:51 NK718 Spirit Airlines Miami — Chicago	9h 48m including layover	Find flight from$160
14:35 — 18:55	14:35 — 16:20 UA4848 United Airlines Knoxville — Washington D.C. 1h 16m stop 17:36 — 18:55 UA1117 United Airlines Washington D.C. — Chicago	5h 20m including layover	Find flight from$127
16:19 — 00:48 +1 day	22:35 — 23:54 F94369 Frontier Airlines Knoxville — Denver 3h 24m stop 19:42 — 23:16 F93174 Frontier Airlines Denver — Chicago	9h 29m including layover	Find flight from$81
16:20 — 22:38	16:20 — 18:00 UA2132 United Airlines Knoxville — Denver 1h 10m stop 19:10 — 22:38 UA2258 United Airlines Denver — Chicago	7h 18m including layover	Find flight from$343
19:24 — 09:55 +1 day	19:24 — 21:10 UA4324 United Airlines Knoxville — Washington D.C. 11h 25m stop 08:35 — 09:55 UA1710 United Airlines Washington D.C. — Chicago	15h 31m including layover	Find flight from$317
19:24 — 14:05 +1 day	19:24 — 21:10 UA4324 United Airlines Knoxville — Washington D.C. 15h 35m stop 12:45 — 14:05 UA1581 United Airlines Washington D.C. — Chicago	19h 41m including layover	Find flight from$353
21:59 — 07:18 +1 day	21:59 — 23:43 G41417 Allegiant Air Knoxville — Orlando 5h 27m stop 05:10 — 07:18 NK1683 Spirit Airlines Orlando — Chicago	10h 19m including layover	Find flight from$178
06:00 — 21:53	06:00 — 08:14 G41403 Allegiant Air Knoxville — Boston 5h 15m stop 13:29 — 16:55 NK502 Spirit Airlines Boston — Orlando 2h 55m stop 19:50 — 21:53 NK1147 Spirit Airlines Orlando — Chicago	16h 53m including layover	Find flight from$314
08:15 — 01:13 +1 day	08:15 — 10:05 G41396 Allegiant Air Knoxville — Newark 3h 47m stop 13:52 — 16:35 NK3718 Spirit Airlines Newark — Dallas 6h 24m stop 22:59 — 01:13 NK828 Spirit Airlines Dallas — Chicago	17h 58m including layover	Find flight from$272
11:00 — 22:55	11:00 — 13:17 G41415 Allegiant Air Knoxville — Miami 2h 50m stop 16:07 — 19:00 NK220 Spirit Airlines Miami — New York 2h 15m stop 21:15 — 22:55 NK225 Spirit Airlines New York — Chicago	12h 55m including layover	Find flight from$173
18:24 — 07:47 +1 day	18:24 — 20:36 G41432 Allegiant Air Knoxville — Miami 2h 8m stop 22:44 — 23:47 NK2054 Spirit Airlines Miami — Tampa 6h 2m stop 05:49 — 07:47 NK1066 Spirit Airlines Tampa — Chicago	14h 23m including layover	Find flight from$379
21:59 — 11:47 +1 day	21:59 — 23:43 G41417 Allegiant Air Knoxville — Orlando 6h 17m stop 06:00 — 08:08 NK538 Spirit Airlines Orlando — Dallas 1h 5m stop 09:13 — 11:47 NK539 Spirit Airlines Dallas — Chicago	14h 48m including layover	Find flight from$213

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on December 21, 2024

Flight Information

Below we will explain in detail what the flights cost on the destination from Knoxville to Chicago depends on and how to choose the most interesting flight option for you.

Distance between Knoxville and Chicago is 745 miles. Time difference between the cities is 1h. Airplanes depart 05:45 to 21:59 from 1 Knoxville airport and arrive 05:45 to 21:59 to 7 Chicago airports. Average flight time is 2h 2m.

The fastest flight 1h 55m
Average flight time 2h 2m
The earliest flight 05:45
The latest flight 21:59
Distance 463 ml

The cheapest months to travel to Chicago are november (from 58 $), january (from 81 $), february (from 117 $).

The most expensive months are december (from 258 $), february (from 117 $), january (from 81 $).

What is the lowest airfare Knoxville to Chicago?

The cheapest plane ticket found by our users is $81. This airfare is for economy class on one-way F94369 flight by Frontier Airlines for January 12, 2025 which leaves Mc Ghee Tyson in Knoxville at 16:19 am and arrives at Chicago O'Hare International at 00:48.

Economy class

$81

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Business class

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First class

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Popular Airlines on the Route

The flight Knoxville — Chicago is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 1 departures per week at the price of from $ 81 . And the most expensive tickets are offered by United Airlines airline - from $ 882.

Direct flights

There are 7 nonstop flights on the route. The fastest direct flight is UA4408 by United Airlines takes 1h 55m and the cheapest is F94369 by Frontier Airlines for $117.

UA - United Airlines

from $117

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Connecting Flights

There are 84 flights with layovers on the route. The fastest connecting flight is UA4311 by United Airlines takes 4h 59m and the cheapest is F94369 by Frontier Airlines for $81.

F9 - Frontier Airlines

from $81

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UA - United Airlines

from $127

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G4 - Allegiant Air

from $139

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Airports

You can fly from Knoxville to Chicago from 1 airports (Mc Ghee Tyson).

Knoxville airports

Mc Ghee Tyson-TYS

from $81
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Chicago airports

O'Hare International-ORD

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Midway-MDW

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Dupage County-DPA

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Chicago FSS-CHI

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Merrill C Meigs (closed)-CGX

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Pal-Waukee-PWK

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Chicago NAS-NOH

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Airplanes

There are flights to Chicago from Knoxville by 3 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Knoxville

You may also consider searching for discounted plane tickets to some other popular places from Knoxville within United States.

Knoxville — Tampa

from $80

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Knoxville — Houston

from $54

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Knoxville — New Orleans

from $56

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Knoxville — Orlando

from $73

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Knoxville — Chicago

from $76

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Knoxville — Boston

from $69

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Knoxville — San Francisco

from $78

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Knoxville — Las Vegas

from $74

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Knoxville — Key West

from $64

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Knoxville — Seattle

from $73

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Top International Destinations from Knoxville

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Knoxville — Cancun

from $69

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Knoxville — Panama City

from $61

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Knoxville — Manchester

from $64

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How to book a plane ticket yourself?

Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
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That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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