Cheap Flights from Knoxville, TN to Houston, TX from $64

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On Cheapflightsplus.com you will find 7 direct and 326 connecting flights from Knoxville to Houston. You can compare airfare deals from 3 airlines and multiple travel sites from $64, book and save on cheap plane tickets and last minute offers. Also check out TYS-HOU flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Knoxville to Houston Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $64 (one-way), $110 (round-trip).

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Best Flights from Knoxville to Houston Today

Take a look at the list of non stop flights and flights with layovers from Knoxville to Houston with the lowest price of $64. The fastest direct flight takes 2h 21m and the fastest connecting – 5h 42m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $64 Find flight	10:00 Knoxville Mc Ghee Tyson	11:31 Houston Hobby	2h 31m	Allegiant Air	G43020
from $81 Find flight	17:20 Knoxville Mc Ghee Tyson	18:47 Houston Hobby	2h 27m	Allegiant Air	G41426
from $133 Find flight	09:00 Knoxville Mc Ghee Tyson	10:21 Houston Hobby	2h 21m	Allegiant Air	G43047
from $331 Find flight	11:50 Knoxville Mc Ghee Tyson	13:26 Houston George Bush	2h 36m	United Airlines	UA4302
from $67 Find flight	19:30 Knoxville Mc Ghee Tyson	08:34+1 день Houston George Bush	14h 4m layover 8h 19m - Denver	Frontier Airlines	F94369 F93230
from $97 Find flight	06:00 Knoxville Mc Ghee Tyson	14:55 Houston George Bush	9h 55m layover 5h 27m - Orlando	Allegiant Air	G43052 NK197
from $134 Find flight	09:00 Knoxville Mc Ghee Tyson	18:06 Houston George Bush	10h 6m layover 5h 52m - Tampa	Allegiant Air	G43061 NK3127
from $157 Find flight	15:02 Knoxville Mc Ghee Tyson	00:23+1 день Houston George Bush	10h 21m layover 5h 58m - Orlando	Allegiant Air	G43050 NK1576
from $165 Find flight	17:44 Knoxville Mc Ghee Tyson	00:28+1 день Houston George Bush	7h 44m layover 3h 27m - Orlando	Allegiant Air	G43063 NK1576
from $175 Find flight	17:15 Knoxville Mc Ghee Tyson	23:52 Houston George Bush	7h 37m layover 2h 22m - Miami	Allegiant Air	G43477 NK693
from $190 Find flight	14:08 Knoxville Mc Ghee Tyson	00:05+1 день Houston George Bush	10h 57m layover 5h 45m - Miami	Allegiant Air	G43040 NK352
from $194 Find flight	18:01 Knoxville Mc Ghee Tyson	23:59 Houston George Bush	6h 58m layover 1h 59m - Miami	Allegiant Air	G4513 NK352
from $194 Find flight	14:03 Knoxville Mc Ghee Tyson	21:56 Houston George Bush	8h 53m layover 3h 34m - Miami	Allegiant Air	G41431 NK931
from $194 Find flight	14:03 Knoxville Mc Ghee Tyson	23:52 Houston George Bush	10h 49m layover 5h 34m - Miami	Allegiant Air	G41431 NK693
from $172 Find flight	13:09 Knoxville Mc Ghee Tyson	00:05+1 день Houston George Bush	11h 56m layover 3h 20m - Orlando 0h 56m - Chicago	Allegiant Air	G4483 NK1147 NK1150
from $180 Find flight	13:50 Knoxville Mc Ghee Tyson	08:38+1 день Houston George Bush	19h 48m layover 5h 22m - Chicago 6h 51m - Miami	Allegiant Air	G43062 NK158 NK1144

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on May 09, 2025

Flight Schedule Knoxville (Tennessee) to Houston (Texas)

Full flight schedule will help you in detecting at what time planes fly from Knoxville to Houston. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
07:05 — 08:50	07:05 — 08:50 UA4913 United Airlines Knoxville — Houston	2h 45m	Find flight from$331
09:00 — 10:21	09:00 — 10:21 G43047 Allegiant Air Knoxville — Houston	2h 21m	Find flight from$133
09:25 — 11:06	09:25 — 11:06 UA4841 United Airlines Knoxville — Houston	2h 41m	Find flight from$331
10:00 — 11:31	10:00 — 11:31 G43020 Allegiant Air Knoxville — Houston	2h 31m	Find flight from$64
11:50 — 13:26	11:50 — 13:26 UA4302 United Airlines Knoxville — Houston	2h 36m	Find flight from$331
16:40 — 18:20	16:40 — 18:20 UA4854 United Airlines Knoxville — Houston	2h 40m	Find flight from$331
17:20 — 18:47	17:20 — 18:47 G41426 Allegiant Air Knoxville — Houston	2h 27m	Find flight from$81
06:00 — 14:55	06:00 — 07:48 G43052 Allegiant Air Knoxville — Orlando 5h 27m stop 13:15 — 14:55 NK197 Spirit Airlines Orlando — Houston	9h 55m including layover	Find flight from$97
07:30 — 16:14	07:30 — 08:53 G41427 Allegiant Air Knoxville — Las Vegas 2h 21m stop 11:14 — 16:14 NK537 Spirit Airlines Las Vegas — Houston	9h 44m including layover	Find flight from$207
07:30 — 20:14	07:30 — 08:53 G41427 Allegiant Air Knoxville — Las Vegas 6h 19m stop 15:12 — 20:14 NK489 Spirit Airlines Las Vegas — Houston	13h 44m including layover	Find flight from$207
08:00 — 15:06	08:00 — 09:36 G43052 Allegiant Air Knoxville — Orlando 3h 56m stop 13:32 — 15:06 NK3142 Spirit Airlines Orlando — Houston	8h 6m including layover	Find flight from$219
09:00 — 18:06	09:00 — 10:43 G43061 Allegiant Air Knoxville — Tampa 5h 52m stop 16:35 — 18:06 NK3127 Spirit Airlines Tampa — Houston	10h 6m including layover	Find flight from$134
11:00 — 21:56	11:00 — 13:17 G41415 Allegiant Air Knoxville — Miami 6h 37m stop 19:54 — 21:56 NK931 Spirit Airlines Miami — Houston	11h 56m including layover	Find flight from$194
11:57 — 20:28	11:57 — 13:45 G43475 Allegiant Air Knoxville — Orlando 4h 52m stop 18:37 — 20:28 NK1311 Spirit Airlines Orlando — Houston	9h 31m including layover	Find flight from$235
14:03 — 21:56	14:03 — 16:20 G41431 Allegiant Air Knoxville — Miami 3h 34m stop 19:54 — 21:56 NK931 Spirit Airlines Miami — Houston	8h 53m including layover	Find flight from$194
14:08 — 00:05 +1 day	14:00 — 16:04 G43040 Allegiant Air Knoxville — Miami 5h 45m stop 22:04 — 23:59 NK352 Spirit Airlines Miami — Houston	10h 57m including layover	Find flight from$190
15:02 — 00:23 +1 day	15:02 — 16:44 G43050 Allegiant Air Knoxville — Orlando 5h 58m stop 22:42 — 00:23 NK1576 Spirit Airlines Orlando — Houston	10h 21m including layover	Find flight from$157
16:13 — 00:41 +1 day	16:13 — 17:51 G43062 Allegiant Air Knoxville — Orlando 5h 4m stop 22:55 — 00:41 NK1576 Spirit Airlines Orlando — Houston	9h 28m including layover	Find flight from$208
16:19 — 09:33 +1 day	16:19 — 17:51 F94369 Frontier Airlines Knoxville — Denver 12h 9m stop 06:00 — 09:33 F91162 Frontier Airlines Denver — Houston	18h 14m including layover	Find flight from$94
17:44 — 00:28 +1 day	17:44 — 19:20 G43063 Allegiant Air Knoxville — Orlando 3h 27m stop 22:47 — 00:28 NK1576 Spirit Airlines Orlando — Houston	7h 44m including layover	Find flight from$165
18:01 — 23:59	18:01 — 20:05 G4513 Allegiant Air Knoxville — Miami 1h 59m stop 22:04 — 23:59 NK352 Spirit Airlines Miami — Houston	6h 58m including layover	Find flight from$194
19:08 — 00:43 +1 day	16:19 — 17:51 F94369 Frontier Airlines Knoxville — Denver 53m stop 20:05 — 23:29 F94856 Frontier Airlines Denver — Houston	6h 35m including layover	Find flight from$87
19:30 — 08:34 +1 day	22:35 — 23:54 F94369 Frontier Airlines Knoxville — Denver 8h 19m stop 20:40 — 00:04 F93230 Frontier Airlines Denver — Houston	14h 4m including layover	Find flight from$67
22:35 — 12:03 +1 day	22:35 — 23:54 F94369 Frontier Airlines Knoxville — Denver 8h 42m stop 08:36 — 12:03 F93206 Frontier Airlines Denver — Houston	14h 28m including layover	Find flight from$67
06:00 — 23:00	06:00 — 07:48 G43052 Allegiant Air Knoxville — Orlando 5h 19m stop 13:07 — 15:51 NK3781 Spirit Airlines Orlando — Detroit 4h 56m stop 20:47 — 23:00 NK3788 Spirit Airlines Detroit — Houston	18h including layover	Find flight from$180
08:15 — 00:23 +1 day	08:10 — 10:05 G41396 Allegiant Air Knoxville — Newark 4h 15m stop 14:20 — 17:16 NK922 Spirit Airlines Newark — Orlando 5h 26m stop 22:42 — 00:23 NK1576 Spirit Airlines Orlando — Houston	17h 8m including layover	Find flight from$223
12:25 — 21:15	12:25 — 14:03 G41420 Allegiant Air Knoxville — Orlando 3h 12m stop 17:15 — 18:59 NK493 Spirit Airlines Orlando — Atlanta 57m stop 19:56 — 21:15 NK2169 Spirit Airlines Atlanta — Houston	9h 50m including layover	Find flight from$206
12:25 — 23:29	12:25 — 14:03 G41420 Allegiant Air Knoxville — Orlando 4h 2m stop 18:05 — 19:05 NK2025 Spirit Airlines Orlando — New Orleans 3h 4m stop 22:09 — 23:29 NK1154 Spirit Airlines New Orleans — Houston	12h 4m including layover	Find flight from$206
13:09 — 00:05 +1 day	13:09 — 14:45 G4483 Allegiant Air Knoxville — Orlando 3h 20m stop 18:05 — 20:15 NK1147 Spirit Airlines Orlando — Chicago 56m stop 21:11 — 00:05 NK1150 Spirit Airlines Chicago — Houston	11h 56m including layover	Find flight from$172
13:50 — 08:38 +1 day	13:50 — 14:24 G43062 Allegiant Air Knoxville — Chicago 5h 22m stop 19:46 — 23:54 NK158 Spirit Airlines Chicago — Miami 6h 51m stop 06:45 — 08:38 NK1144 Spirit Airlines Miami — Houston	19h 48m including layover	Find flight from$180
15:17 — 09:30 +1 day	15:17 — 17:16 G4496 Allegiant Air Knoxville — Miami 5h 54m stop 23:10 — 00:18 NK676 Spirit Airlines Miami — Orlando 7h 29m stop 07:47 — 09:30 NK480 Spirit Airlines Orlando — Houston	19h 13m including layover	Find flight from$227
18:46 — 13:15 +1 day	18:46 — 20:07 G488 Allegiant Air Knoxville — Las Vegas 2h 3m stop 22:10 — 23:25 NK211 Spirit Airlines Las Vegas — Los Angeles 8h 42m stop 08:07 — 13:15 NK421 Spirit Airlines Los Angeles — Houston	19h 29m including layover	Find flight from$249
21:59 — 16:16 +1 day	21:59 — 23:43 G41417 Allegiant Air Knoxville — Orlando 5h 27m stop 05:10 — 07:18 NK1683 Spirit Airlines Orlando — Chicago 6h 1m stop 13:19 — 16:16 NK1684 Spirit Airlines Chicago — Houston	19h 17m including layover	Find flight from$226

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on May 9, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Knoxville to Houston depends on and how to choose the most interesting flight option for you.

Distance between Knoxville and Houston is 1257 miles. Time difference between the cities is 1h. Airplanes depart 05:45 to 22:35 from 1 Knoxville airport and arrive 05:45 to 22:35 to 15 Houston airports. Average flight time is 2h 36m.

The fastest flight 2h 21m
Average flight time 2h 36m
The earliest flight 05:45
The latest flight 22:35
Distance 782 ml

The cheapest months to travel to Houston are december (from 64 $), november (from 67 $), february (from 175 $).

The most expensive months are january (from 194 $), february (from 175 $), november (from 67 $).

What is the lowest airfare Knoxville to Houston?

The cheapest plane ticket found by our users is $64. This airfare is for economy class on one-way G43020 flight by Allegiant Air for December 13, 2024 which leaves Mc Ghee Tyson in Knoxville at 10:00 am and arrives at Houston Hobby at 11:31.

Economy class

$64

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Business class

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First class

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Popular Airlines on the Route

The flight Knoxville — Houston is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 4 departures per week at the price of from $ 67 . And the most expensive tickets are offered by United Airlines airline - from $ 868.

Direct flights

There are 7 nonstop flights on the route. The fastest direct flight is G43047 by Allegiant Air takes 2h 21m and the cheapest is G43020 by Allegiant Air for $64.

UA - United Airlines

from $331

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G4 - Allegiant Air

from $64

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Connecting Flights

There are 326 flights with layovers on the route. The fastest connecting flight is UA776 by United Airlines takes 5h 42m and the cheapest is G43020 by Allegiant Air for $67.

F9 - Frontier Airlines

from $67

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UA - United Airlines

from $314

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G4 - Allegiant Air

from $97

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Airports

You can fly from Knoxville to Houston from 1 airports (Mc Ghee Tyson).

Knoxville airports

Mc Ghee Tyson-TYS

from $64
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Houston airports

Ellington Field-EFD

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West Houston-IWS

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Hobby-HOU

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Park Ten Heliport-JPT

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Andrau Airpark-AAP

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George Bush-IAH

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Greenway Plaza H/P-JGP

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David Wayne Hooks-DWH

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Transco Twr Galleria-JGQ

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Westchase Hilton H/P-JWH

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Spaceland-SPX

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Woodlawns-JWL

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Marriot Astrodome Heliport-JMA

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Central Bus. District-JDX

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Houston Municipal-SGR

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Airplanes

There are flights to Houston from Knoxville by 3 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Knoxville

You may also consider searching for discounted plane tickets to some other popular places from Knoxville within United States.

Knoxville — Orlando

from $73

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Knoxville — Las Vegas

from $74

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Knoxville — Chicago

from $76

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Knoxville — Denver

from $74

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Knoxville — Miami

from $66

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Knoxville — Boston

from $69

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Knoxville — Houston

from $54

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Knoxville — New Orleans

from $56

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Knoxville — Tampa

from $80

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Knoxville — Austin

from $54

Find

Top International Destinations from Knoxville

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Knoxville — Cancun

from $69

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Knoxville — Panama City

from $61

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How to book a plane ticket yourself?

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That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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