Cheap Flights from Knoxville, TN to Houston, TX from $39

Return flight: Houston – Knoxville

On Cheapflightsplus.com you will find 8 direct and 307 connecting flights from Knoxville to Houston. You can compare airfare deals from 3 airlines and multiple travel sites from $39, book and save on cheap plane tickets and last minute offers. Also check out TYS-HOU flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Knoxville to Houston Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $39 (one-way), $67 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Knoxville to Houston. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
07:00 — 08:24
07:00 — 08:24 UA4913 United Airlines
Knoxville — Houston
2h 24m
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from$204
09:15 — 10:39
09:15 — 10:39 UA4841 United Airlines
Knoxville — Houston
2h 24m
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from$204
12:00 — 13:27
12:00 — 13:27 UA4302 United Airlines
Knoxville — Houston
2h 27m
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from$206
17:00 — 18:27
17:00 — 18:27 UA4854 United Airlines
Knoxville — Houston
2h 27m
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from$206
17:02 — 18:13
17:02 — 18:13 G41437 Allegiant Air
Knoxville — Houston
2h 11m
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from$39
17:15 — 18:39
17:15 — 18:39 UA6068 United Airlines
Knoxville — Houston
2h 24m
Find flight
from$206
17:15 — 18:39
17:15 — 18:39 UA6056 United Airlines
Knoxville — Houston
2h 24m
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from$207
17:47 — 19:12
17:47 — 19:12 G43041 Allegiant Air
Knoxville — Houston
2h 25m
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from$39
07:10 — 13:22
07:10 — 09:05 G43038 Allegiant Air
Knoxville — Newark
1h 33m stop
10:38 — 13:22 NK1937 Spirit Airlines
Newark — Houston
7h 12m
including layover
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from$104
11:01 — 20:54
11:01 — 12:19 G43064 Allegiant Air
Knoxville — Minneapolis
5h 41m stop
18:00 — 20:54 SY1681 Sun Country Airlines
Minneapolis — Houston
10h 53m
including layover
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from$98
11:23 — 16:49
11:08 — 13:12 G4502 Allegiant Air
Knoxville — Miami
1h 43m stop
15:06 — 16:49 NK909 Spirit Airlines
Miami — Houston
6h 26m
including layover
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from$120
12:45 — 14:06
+1 day
12:45 — 14:23 G41397 Allegiant Air
Knoxville — Baltimore
21h 10m stop
11:33 — 14:06 NK2175 Spirit Airlines
Baltimore — Houston
26h 21m
including layover
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from$76
21:08 — 07:48
+1 day
21:08 — 23:08 G42158 Allegiant Air
Knoxville — Miami
6h 52m stop
06:00 — 07:48 NK2082 Spirit Airlines
Miami — Houston
11h 40m
including layover
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from$100
21:08 — 15:30
+1 day
21:08 — 23:08 G42158 Allegiant Air
Knoxville — Miami
14h 31m stop
13:39 — 15:30 NK2678 Spirit Airlines
Miami — Houston
19h 22m
including layover
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from$125
06:00 — 23:10
06:00 — 07:37 G43063 Allegiant Air
Knoxville — Orlando
3h 18m stop
10:55 — 11:43 NK1572 Spirit Airlines
Orlando — New Orleans
10h 7m stop
21:50 — 23:10 NK1428 Spirit Airlines
New Orleans — Houston
18h 10m
including layover
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from$129
06:55 — 19:13
06:55 — 08:15 G41410 Allegiant Air
Knoxville — Austin
5h 7m stop
13:22 — 16:46 G41872 Allegiant Air
Austin — Fletcher
1h 6m stop
17:52 — 19:13 G41840 Allegiant Air
Fletcher — Houston
13h 18m
including layover
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from$120
07:00 — 19:13
+1 day
07:00 — 08:41 G43048 Allegiant Air
Knoxville — Clearwater
10h 38m stop
17:19 — 18:56 G4220 Allegiant Air
Clearwater — Fletcher
20h 56m stop
17:52 — 19:13 G41840 Allegiant Air
Fletcher — Houston
37h 13m
including layover
Find flight
from$116
08:00 — 22:03
08:00 — 10:11 G41396 Allegiant Air
Knoxville — Boston
1h 45m stop
11:56 — 15:17 NK2887 Spirit Airlines
Boston — Miami
5h 3m stop
20:20 — 22:03 NK352 Spirit Airlines
Miami — Houston
15h 3m
including layover
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from$114
08:00 — 00:15
+1 day
08:00 — 10:11 G41396 Allegiant Air
Knoxville — Boston
6h 29m stop
16:40 — 19:57 NK3797 Spirit Airlines
Boston — Orlando
2h 48m stop
22:45 — 00:15 NK1576 Spirit Airlines
Orlando — Houston
17h 15m
including layover
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from$114
09:02 — 19:13
09:02 — 10:51 G4869 Allegiant Air
Knoxville — Punta Gorda
1h 46m stop
12:37 — 14:25 G4858 Allegiant Air
Punta Gorda — Fletcher
3h 27m stop
17:52 — 19:13 G41840 Allegiant Air
Fletcher — Houston
11h 11m
including layover
Find flight
from$118
09:02 — 19:13
09:02 — 10:51 G4865 Allegiant Air
Knoxville — Punta Gorda
1h 46m stop
12:37 — 14:25 G4857 Allegiant Air
Punta Gorda — Fletcher
3h 27m stop
17:52 — 19:13 G41840 Allegiant Air
Fletcher — Houston
11h 11m
including layover
Find flight
from$120
12:45 — 19:10
+1 day
12:45 — 14:23 G41397 Allegiant Air
Knoxville — Baltimore
17h 37m stop
08:00 — 10:01 NK2377 Spirit Airlines
Baltimore — Las Vegas
4h 2m stop
14:03 — 19:10 NK880 Spirit Airlines
Las Vegas — Houston
31h 25m
including layover
Find flight
from$102
15:11 — 19:13
+1 day
15:11 — 17:12 G4497 Allegiant Air
Knoxville — Miami
2h 53m stop
20:05 — 22:06 G4261 Allegiant Air
Miami — Fletcher
19h 46m stop
17:52 — 19:13 G41840 Allegiant Air
Fletcher — Houston
29h 2m
including layover
Find flight
from$123
15:11 — 19:13
+1 day
15:11 — 17:12 G4497 Allegiant Air
Knoxville — Miami
16h 33m stop
09:45 — 11:46 G4262 Allegiant Air
Miami — Fletcher
6h 6m stop
17:52 — 19:13 G41840 Allegiant Air
Fletcher — Houston
29h 2m
including layover
Find flight
from$124
20:54 — 19:13
+1 day
20:54 — 22:55 G42154 Allegiant Air
Knoxville — Miami
10h 50m stop
09:45 — 11:46 G4262 Allegiant Air
Miami — Fletcher
6h 6m stop
17:52 — 19:13 G41840 Allegiant Air
Fletcher — Houston
23h 19m
including layover
Find flight
from$108
*Departure and arrival times - local. Updated on June 25, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Knoxville to Houston depends on and how to choose the most interesting flight option for you.

Distance between Knoxville and Houston is 1257 miles. Time difference between the cities is 1h. Airplanes depart 05:45 to 21:30 from 1 Knoxville airport and arrive 05:45 to 21:30 to 15 Houston airports. Average flight time is 2h 24m.

  • The fastest flight 2h 11m
  • Average flight time 2h 24m
  • The earliest flight 05:45
  • The latest flight 21:30
  • Distance 782 ml

The cheapest months to travel to Houston are may (from 49 $), july (from 53 $), august (from 53 $).

The most expensive months are january (from 739 $), november (from 390 $), february (from 346 $).

What is the lowest airfare Knoxville to Houston?

The cheapest plane ticket found by our users is $39. This airfare is for economy class on one-way G43041 flight by Allegiant Air for August 15, 2025 which leaves Mc Ghee Tyson in Knoxville at 17:47 am and arrives at Houston Hobby at 19:12.

Economy class
$39
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Business class
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First class
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Popular Airlines on the Route

The flight Knoxville — Houston is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 1 departures per week at the price of from $ 81 . And the most expensive tickets are offered by United Airlines airline - from $ 531.

Direct flights

There are 8 nonstop flights on the route. The fastest direct flight is G41437 by Allegiant Air takes 2h 11m and the cheapest is G43041 by Allegiant Air for $39.

  • UA - United Airlines
    from $204
    Find
  • G4 - Allegiant Air
    from $39
    Find
See more direct flights

Connecting Flights

There are 307 flights with layovers on the route. The fastest connecting flight is UA5767 by United Airlines takes 5h 38m and the cheapest is G43041 by Allegiant Air for $76.

  • F9 - Frontier Airlines
    from $81
    Find
  • UA - United Airlines
    from $206
    Find
  • G4 - Allegiant Air
    from $76
    Find
See more connecting flights

Airports

You can fly from Knoxville to Houston from 1 airports (Mc Ghee Tyson).

Knoxville airports

  • Mc Ghee Tyson-TYS
    from $39
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Houston airports

  • Ellington Field-EFD
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  • West Houston-IWS
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  • Hobby-HOU
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  • Park Ten Heliport-JPT
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  • Andrau Airpark-AAP
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  • George Bush-IAH
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  • Greenway Plaza H/P-JGP
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  • David Wayne Hooks-DWH
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  • Transco Twr Galleria-JGQ
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  • Westchase Hilton H/P-JWH
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  • Spaceland-SPX
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  • Woodlawns-JWL
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  • Marriot Astrodome Heliport-JMA
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  • Central Bus. District-JDX
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  • Houston Municipal-SGR
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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