Cheap Flights from Knoxville, TN to Houston, TX from $53

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On Cheapflightsplus.com you will find 9 direct and 516 connecting flights from Knoxville to Houston. You can compare airfare deals from 3 airlines and multiple travel sites from $53, book and save on cheap plane tickets and last minute offers. Also check out TYS-HOU flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Knoxville to Houston Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $53 (one-way), $91 (round-trip).

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Best Flights from Knoxville to Houston Today

Take a look at the list of non stop flights and flights with layovers from Knoxville to Houston with the lowest price of $53. The fastest direct flight takes 2h 10m and the fastest connecting – 5h 38m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $53 Find flight	17:01 Knoxville Mc Ghee Tyson	18:11 Houston Hobby	2h 10m	Allegiant Air	G43036
from $53 Find flight	17:47 Knoxville Mc Ghee Tyson	19:12 Houston Hobby	2h 25m	Allegiant Air	G43041
from $72 Find flight	17:02 Knoxville Mc Ghee Tyson	18:13 Houston Hobby	2h 11m	Allegiant Air	G41437
from $274 Find flight	07:00 Knoxville Mc Ghee Tyson	08:24 Houston George Bush	2h 24m	United Airlines	UA4913
from $103 Find flight	12:45 Knoxville Mc Ghee Tyson	14:06+1 день Houston George Bush	26h 21m layover 21h 10m - Baltimore	Allegiant Air	G41397 NK2175
from $110 Find flight	17:25 Knoxville Mc Ghee Tyson	23:36 Houston George Bush	7h 11m layover 1h 13m - Denver	Frontier Airlines	F94369 F92996
from $120 Find flight	14:47 Knoxville Mc Ghee Tyson	00:07+1 день Houston George Bush	10h 20m layover 5h 25m - Miami	Allegiant Air	G4487 NK2062
from $120 Find flight	21:03 Knoxville Mc Ghee Tyson	07:53+1 день Houston George Bush	11h 50m layover 6h 58m - Miami	Allegiant Air	G42125 NK2082
from $120 Find flight	20:35 Knoxville Mc Ghee Tyson	07:53+1 день Houston George Bush	12h 18m layover 7h 27m - Miami	Allegiant Air	G4519 NK2082
from $120 Find flight	21:03 Knoxville Mc Ghee Tyson	00:07+2 дня Houston George Bush	28h 4m layover 23h 9m - Miami	Allegiant Air	G42125 NK2062
from $131 Find flight	07:15 Knoxville Mc Ghee Tyson	14:44 Houston George Bush	8h 29m layover 3h 0m - Newark	Allegiant Air	G41396 NK2064
from $131 Find flight	11:01 Knoxville Mc Ghee Tyson	20:54 Houston Hobby	10h 53m layover 5h 41m - Minneapolis	Allegiant Air	G43064 SY1681
from $131 Find flight	09:09 Knoxville Mc Ghee Tyson	00:07+1 день Houston George Bush	15h 58m layover 11h 7m - Miami	Allegiant Air	G42148 NK2062
from $135 Find flight	21:08 Knoxville Mc Ghee Tyson	07:48+1 день Houston George Bush	11h 40m layover 6h 52m - Miami	Allegiant Air	G42158 NK2082
from $133 Find flight	07:15 Knoxville Mc Ghee Tyson	13:50+1 день Houston George Bush	31h 35m layover 20h 55m - New York 2h 58m - Miami	Allegiant Air	G41396 NK2005 NK2678
from $133 Find flight	07:15 Knoxville Mc Ghee Tyson	13:50+1 день Houston George Bush	31h 35m layover 20h 10m - Newark 3h 40m - Miami	Allegiant Air	G41396 NK2059 NK2678

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on August 08, 2025

Flight Schedule Knoxville (Tennessee) to Houston (Texas)

Full flight schedule will help you in detecting at what time planes fly from Knoxville to Houston. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
07:00 — 08:24	07:00 — 08:24 UA4913 United Airlines Knoxville — Houston	2h 24m	Find flight from$274
09:15 — 10:39	09:15 — 10:39 UA4841 United Airlines Knoxville — Houston	2h 24m	Find flight from$274
12:00 — 13:27	12:00 — 13:27 UA4302 United Airlines Knoxville — Houston	2h 27m	Find flight from$276
17:00 — 18:27	17:00 — 18:27 UA4854 United Airlines Knoxville — Houston	2h 27m	Find flight from$276
17:01 — 18:11	17:01 — 18:11 G43036 Allegiant Air Knoxville — Houston	2h 10m	Find flight from$53
17:02 — 18:13	17:02 — 18:13 G41437 Allegiant Air Knoxville — Houston	2h 11m	Find flight from$72
17:15 — 18:39	17:15 — 18:39 UA6068 United Airlines Knoxville — Houston	2h 24m	Find flight from$276
17:15 — 18:39	17:15 — 18:39 UA6056 United Airlines Knoxville — Houston	2h 24m	Find flight from$278
17:47 — 19:12	17:47 — 19:12 G43041 Allegiant Air Knoxville — Houston	2h 25m	Find flight from$53
07:15 — 14:44	07:15 — 09:05 G41396 Allegiant Air Knoxville — Newark 3h stop 12:05 — 14:44 NK2064 Spirit Airlines Newark — Houston	8h 29m including layover	Find flight from$131
08:52 — 18:25	21:34 — 23:34 G42120 Allegiant Air Knoxville — Miami 5h 36m stop 11:56 — 13:50 NK2678 Spirit Airlines Miami — Houston	10h 33m including layover	Find flight from$137
09:09 — 00:07 +1 day	09:09 — 11:09 G42148 Allegiant Air Knoxville — Miami 11h 7m stop 22:16 — 00:07 NK2062 Spirit Airlines Miami — Houston	15h 58m including layover	Find flight from$131
09:09 — 07:53 +1 day	09:09 — 11:09 G42148 Allegiant Air Knoxville — Miami 18h 56m stop 06:05 — 07:53 NK2082 Spirit Airlines Miami — Houston	23h 44m including layover	Find flight from$137
11:01 — 20:54	11:01 — 12:19 G43064 Allegiant Air Knoxville — Minneapolis 5h 41m stop 18:00 — 20:54 SY1681 Sun Country Airlines Minneapolis — Houston	10h 53m including layover	Find flight from$131
11:23 — 16:49	11:08 — 13:12 G4502 Allegiant Air Knoxville — Miami 1h 43m stop 15:06 — 16:49 NK909 Spirit Airlines Miami — Houston	6h 26m including layover	Find flight from$162
12:45 — 14:06 +1 day	12:45 — 14:23 G41397 Allegiant Air Knoxville — Baltimore 21h 10m stop 11:33 — 14:06 NK2175 Spirit Airlines Baltimore — Houston	26h 21m including layover	Find flight from$103
12:45 — 21:10	12:45 — 14:23 G41397 Allegiant Air Knoxville — Baltimore 4h 27m stop 18:50 — 21:10 NK2400 Spirit Airlines Baltimore — Houston	9h 25m including layover	Find flight from$126
14:47 — 00:07 +1 day	14:47 — 16:51 G4487 Allegiant Air Knoxville — Miami 5h 25m stop 22:16 — 00:07 NK2062 Spirit Airlines Miami — Houston	10h 20m including layover	Find flight from$120
14:47 — 07:53 +1 day	14:47 — 16:51 G4487 Allegiant Air Knoxville — Miami 13h 14m stop 06:05 — 07:53 NK2082 Spirit Airlines Miami — Houston	18h 6m including layover	Find flight from$120
20:35 — 07:53 +1 day	20:35 — 22:38 G4519 Allegiant Air Knoxville — Miami 7h 27m stop 06:05 — 07:53 NK2082 Spirit Airlines Miami — Houston	12h 18m including layover	Find flight from$120
20:35 — 00:07 +2 days	20:35 — 22:38 G4519 Allegiant Air Knoxville — Miami 23h 38m stop 22:16 — 00:07 NK2062 Spirit Airlines Miami — Houston	28h 32m including layover	Find flight from$140
21:03 — 07:53 +1 day	21:03 — 23:07 G42125 Allegiant Air Knoxville — Miami 6h 58m stop 06:05 — 07:53 NK2082 Spirit Airlines Miami — Houston	11h 50m including layover	Find flight from$120
21:03 — 00:07 +2 days	21:03 — 23:07 G42125 Allegiant Air Knoxville — Miami 23h 9m stop 22:16 — 00:07 NK2062 Spirit Airlines Miami — Houston	28h 4m including layover	Find flight from$120
07:15 — 13:50 +1 day	07:15 — 09:05 G41396 Allegiant Air Knoxville — New York 20h 55m stop 06:00 — 08:58 NK2005 Spirit Airlines New York — Miami 2h 58m stop 11:56 — 13:50 NK2678 Spirit Airlines Miami — Houston	31h 35m including layover	Find flight from$133
08:00 — 22:03	08:00 — 10:11 G41396 Allegiant Air Knoxville — Boston 1h 45m stop 11:56 — 15:17 NK2887 Spirit Airlines Boston — Miami 5h 3m stop 20:20 — 22:03 NK352 Spirit Airlines Miami — Houston	15h 3m including layover	Find flight from$152

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on August 8, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Knoxville to Houston depends on and how to choose the most interesting flight option for you.

Distance between Knoxville and Houston is 1257 miles. Time difference between the cities is 1h. Airplanes depart 05:45 to 21:34 from 1 Knoxville airport and arrive 05:45 to 21:34 to 15 Houston airports. Average flight time is 2h 24m.

The fastest flight 2h 10m
Average flight time 2h 24m
The earliest flight 05:45
The latest flight 21:34
Distance 782 ml

The cheapest months to travel to Houston are may (from 49 $), july (from 53 $), june (from 53 $).

The most expensive months are january (from 742 $), november (from 392 $), february (from 347 $).

What is the lowest airfare Knoxville to Houston?

The cheapest plane ticket found by our users is $53. This airfare is for economy class on one-way G43041 flight by Allegiant Air for August 15, 2025 which leaves Mc Ghee Tyson in Knoxville at 17:47 am and arrives at Houston Hobby at 19:12.

Economy class

$53

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Business class

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First class

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Popular Airlines on the Route

The flight Knoxville — Houston is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 2 departures per week at the price of from $ 110 . And the most expensive tickets are offered by United Airlines airline - from $ 2038.

Direct flights

There are 9 nonstop flights on the route. The fastest direct flight is G43036 by Allegiant Air takes 2h 10m and the cheapest is G43041 by Allegiant Air for $53.

UA - United Airlines

from $274

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G4 - Allegiant Air

from $53

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Connecting Flights

There are 516 flights with layovers on the route. The fastest connecting flight is UA5767 by United Airlines takes 5h 38m and the cheapest is G43041 by Allegiant Air for $103.

F9 - Frontier Airlines

from $110

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UA - United Airlines

from $276

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G4 - Allegiant Air

from $103

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Airports

You can fly from Knoxville to Houston from 1 airports (Mc Ghee Tyson).

Knoxville airports

Mc Ghee Tyson-TYS

from $53
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Houston airports

Ellington Field-EFD

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West Houston-IWS

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Hobby-HOU

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Park Ten Heliport-JPT

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Andrau Airpark-AAP

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George Bush-IAH

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Greenway Plaza H/P-JGP

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David Wayne Hooks-DWH

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Transco Twr Galleria-JGQ

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Westchase Hilton H/P-JWH

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Spaceland-SPX

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Woodlawns-JWL

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Marriot Astrodome Heliport-JMA

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Central Bus. District-JDX

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Houston Municipal-SGR

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Airplanes

There are flights to Houston from Knoxville by 3 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Knoxville

You may also consider searching for discounted plane tickets to some other popular places from Knoxville within United States.

Knoxville — Orlando

from $73

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Knoxville — Las Vegas

from $74

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Knoxville — Chicago

from $76

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Knoxville — Denver

from $74

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Knoxville — Miami

from $66

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Knoxville — Boston

from $69

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Knoxville — Houston

from $54

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Knoxville — New Orleans

from $56

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Knoxville — Tampa

from $80

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Knoxville — Austin

from $54

Find

Top International Destinations from Knoxville

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Knoxville — Cancun

from $69

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Knoxville — Panama City

from $61

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How to book a plane ticket yourself?

Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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