Cheap Flights from Knoxville, TN to Houston, TX from $46

Return flight: Houston – Knoxville

On Cheapflightsplus.com you will find 9 direct and 516 connecting flights from Knoxville to Houston. You can compare airfare deals from 3 airlines and multiple travel sites from $46, book and save on cheap plane tickets and last minute offers. Also check out TYS-HOU flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Knoxville to Houston depends on and how to choose the most interesting flight option for you.

Distance between Knoxville and Houston is 1257 miles. Time difference between the cities is 1h. Airplanes depart 05:45 to 21:34 from 1 Knoxville airport and arrive 05:45 to 21:34 to 15 Houston airports. Average flight time is 2h 24m.

  • The fastest flight 2h 10m
  • Average flight time 2h 24m
  • The earliest flight 05:45
  • The latest flight 21:34
  • Distance 782 ml

The cheapest months to travel to Houston are may (from 46 $), july (from 50 $), june (from 50 $).

The most expensive months are january (from 703 $), november (from 371 $), february (from 329 $).

What is the lowest airfare Knoxville to Houston?

The cheapest plane ticket found by our users is $46. This airfare is for economy class on one-way G43041 flight by Allegiant Air for August 15, 2025 which leaves Mc Ghee Tyson in Knoxville at 17:47 am and arrives at Houston Hobby at 19:12.

Economy class
$46
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Business class
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First class
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Flight Schedule Knoxville (Tennessee) to Houston (Texas)

07:00 — 08:24
2h 24m flight time
Find flight
from$260
Knoxville — Houston
UA4913 United Airlines
09:15 — 10:39
2h 24m flight time
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from$260
Knoxville — Houston
UA4841 United Airlines
12:00 — 13:27
2h 27m flight time
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from$261
Knoxville — Houston
UA4302 United Airlines
12:45 — 14:06+1day
26h 21m flight time
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from$97
12:45 — 14:23 Knoxville — Baltimore
G41397 Allegiant Air
21h 10m stop
11:33 — 14:06 Baltimore — Houston
NK2175 Spirit Airlines
14:47 — 00:07+1day
10h 20m flight time
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from$113
14:47 — 16:51 Knoxville — Miami
G4487 Allegiant Air
5h 25m stop
22:16 — 00:07 Miami — Houston
NK2062 Spirit Airlines
14:47 — 07:53+1day
18h 6m flight time
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from$113
14:47 — 16:51 Knoxville — Miami
G4487 Allegiant Air
13h 14m stop
06:05 — 07:53 Miami — Houston
NK2082 Spirit Airlines
17:00 — 18:27
2h 27m flight time
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from$261
Knoxville — Houston
UA4854 United Airlines
17:01 — 18:11
2h 10m flight time
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from$50
Knoxville — Houston
G43036 Allegiant Air
17:02 — 18:13
2h 11m flight time
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from$50
Knoxville — Houston
G41437 Allegiant Air
17:15 — 18:39
2h 24m flight time
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from$261
Knoxville — Houston
UA6068 United Airlines
17:15 — 18:39
2h 24m flight time
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from$263
Knoxville — Houston
UA6056 United Airlines
17:25 — 23:36
7h 11m flight time
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from$104
17:30 — 19:01 Knoxville — Denver
F94369 Frontier Airlines
1h 13m stop
20:15 — 23:59 Denver — Houston
F92996 Frontier Airlines
17:47 — 19:12
2h 25m flight time
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from$46
Knoxville — Houston
G43041 Allegiant Air
20:35 — 07:53+1day
12h 18m flight time
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from$113
20:35 — 22:38 Knoxville — Miami
G4519 Allegiant Air
7h 27m stop
06:05 — 07:53 Miami — Houston
NK2082 Spirit Airlines
21:03 — 07:53+1day
11h 50m flight time
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from$113
21:03 — 23:07 Knoxville — Miami
G42125 Allegiant Air
6h 58m stop
06:05 — 07:53 Miami — Houston
NK2082 Spirit Airlines
Full flight schedule will help you in detecting at what time planes fly from Knoxville to Houston. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on October 16, 2025.

Popular Airlines on the Route

The flight Knoxville — Houston is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 2 departures per week at the price of from $ 104 . And the most expensive tickets are offered by United Airlines airline - from $ 1929.

Direct flights

There are 9 nonstop flights on the route. The fastest direct flight is G43036 by Allegiant Air takes 2h 10m and the cheapest is G43041 by Allegiant Air for $46.

  • UA - United Airlines
    from $260
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  • G4 - Allegiant Air
    from $46
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See more direct flights

Connecting Flights

There are 516 flights with layovers on the route. The fastest connecting flight is UA5767 by United Airlines takes 5h 38m and the cheapest is G43041 by Allegiant Air for $97.

  • F9 - Frontier Airlines
    from $104
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  • UA - United Airlines
    from $262
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  • G4 - Allegiant Air
    from $97
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See more connecting flights

Airports

You can fly from Knoxville to Houston from 1 airports (Mc Ghee Tyson).

Knoxville airports

  • Mc Ghee Tyson-TYS
    from $46
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Houston airports

  • Ellington Field-EFD
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  • West Houston-IWS
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  • Hobby-HOU
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  • Park Ten Heliport-JPT
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  • Andrau Airpark-AAP
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  • George Bush-IAH
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  • Greenway Plaza H/P-JGP
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  • David Wayne Hooks-DWH
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  • Transco Twr Galleria-JGQ
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  • Westchase Hilton H/P-JWH
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  • Spaceland-SPX
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  • Woodlawns-JWL
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  • Marriot Astrodome Heliport-JMA
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  • Central Bus. District-JDX
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  • Houston Municipal-SGR
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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