Cheap Flights from Houston, TX to Knoxville, TN from $370
On Cheapflightsplus.com you will find 44 connecting flights from Houston to Knoxville. You can compare airfare deals from 4 airlines and multiple travel sites from $370, book and save on cheap plane tickets and last minute offers. Also check out HOU-TYS flight schedule to find best flight time, convenient departure and arrival airports.
Flight Information
Below we will explain in detail what the flights cost on the destination from Houston to Knoxville depends on and how to choose the most interesting flight option for you.
Distance between Houston and Knoxville is 1257 miles. Time difference between the cities is 1h. Airplanes depart 06:30 to 21:57 from 15 Houston airports and arrive 06:30 to 21:57 to 1 Knoxville airport. Average flight time is 16h 29m.
- The fastest flight 6h 55m
- Average flight time 16h 29m
- The earliest flight 06:30
- The latest flight 21:57
- Distance 782 ml
Best Flights from Houston to Knoxville Today
| Price | Departure | Arrival | Flight Duration | Airline | Flight |
|---|---|---|---|---|---|
| from $376 | 21:34 Houston George Bush | 10:13+1 день Knoxville Mc Ghee Tyson | 11h 39m layover 7h 3m - Chicago | United Airlines | UA2234 UA5726 |
| from $459 | 06:30 Houston George Bush | 16:47 Knoxville Mc Ghee Tyson | 9h 17m layover 4h 41m - Washington D.C. | Spirit Airlines | NK2317 G41398 |
| from $370 | 16:30 Houston George Bush | 13:11+2 дня Knoxville Mc Ghee Tyson | 43h 41m layover 15h 2m - Raleigh 21h 58m - Clearwater | Frontier Airlines | F94610 F93373 G43063 |
| from $492 | 18:15 Houston Hobby | 15:51+1 день Knoxville Mc Ghee Tyson | 20h 36m layover 7h 31m - New Haven 4h 17m - Miami | Casino Express | XP300 XP323 G41876 |
The cheapest months to travel to Knoxville are august (from 370 $), september (from 376 $), october (from 463 $).
The most expensive months are june (from 463 $), october (from 463 $), september (from 376 $).
What is the lowest airfare Houston to Knoxville?
The cheapest plane ticket found by our users is $370. This airfare is for economy class on one-way F94610 flight by Frontier Airlines for August 29, 2025 which leaves George Bush in Houston at 16:30 am and arrives at Knoxville Mc Ghee Tyson at 13:11.
Flight Schedule Houston (Texas) to Knoxville (Tennessee)
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Popular Airlines on the Route
The flight Houston — Knoxville is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 6 departures per week at the price of from $ 370 . And the most expensive tickets are offered by United Airlines airline - from $ 909.
Direct flights
There’re no direct flights on this route. Try flights with stops.
Connecting Flights
There are 44 flights with layovers on the route. The fastest connecting flight is UA2433 by United Airlines takes 6h 55m and the cheapest is F94610 by Frontier Airlines for $370.
- F9 - Frontier Airlinesfrom $370Find
- XP - Casino Expressfrom $492Find
- UA - United Airlinesfrom $376Find
- NK - Spirit Airlinesfrom $459Find
Airports
You can fly from Houston to Knoxville from 15 airports (Ellington Field, West Houston, Hobby, Park Ten Heliport, Andrau Airpark, George Bush, Greenway Plaza H/P, David Wayne Hooks, Transco Twr Galleria, Westchase Hilton H/P, Spaceland, Woodlawns, Marriot Astrodome Heliport, Central Bus. District, Houston Municipal).
Houston airports
- Ellington Field-EFDFind
- West Houston-IWSFind
- Hobby-HOUfrom $492Find
- Park Ten Heliport-JPTFind
- Andrau Airpark-AAPFind
- George Bush-IAHfrom $370Find
- Greenway Plaza H/P-JGPFind
- David Wayne Hooks-DWHFind
- Transco Twr Galleria-JGQFind
- Westchase Hilton H/P-JWHFind
- Spaceland-SPXFind
- Woodlawns-JWLFind
- Marriot Astrodome Heliport-JMAFind
- Central Bus. District-JDXFind
- Houston Municipal-SGRFind
Knoxville airports
- Mc Ghee Tyson-TYSFind
Airplanes
There are flights to Knoxville from Houston by 4 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Houston
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Top International Destinations from Houston
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
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How to book a plane ticket yourself?
- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
- Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
- Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
- Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
- That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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