Cheap Flights from Houston, TX to Knoxville, TN from $150

Return flight: Knoxville – Houston

On Cheapflightsplus.com you will find 42 connecting flights from Houston to Knoxville. You can compare airfare deals from 3 airlines and multiple travel sites from $150, book and save on cheap plane tickets and last minute offers. Also check out HOU-TYS flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Houston to Knoxville Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $150 (one-way), $257 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Houston to Knoxville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
05:30 — 16:14
05:30 — 09:06 NK221 Spirit Airlines
Houston — Miami
4h 59m stop
14:05 — 16:14 G41402 Allegiant Air
Miami — Knoxville
9h 44m
including layover
Find flight
from$230
06:30 — 23:00
06:30 — 09:18 UA1677 United Airlines
Houston — Chicago
10h 57m stop
20:15 — 23:00 UA1871 United Airlines
Chicago — Knoxville
15h 30m
including layover
Find flight
from$304
06:30 — 16:54
06:30 — 09:18 UA1677 United Airlines
Houston — Chicago
4h 52m stop
14:10 — 16:54 UA5379 United Airlines
Chicago — Knoxville
9h 24m
including layover
Find flight
from$405
08:30 — 18:18
08:30 — 09:05 NK3726 Spirit Airlines
Houston — Las Vegas
2h 33m stop
11:38 — 18:18 G41399 Allegiant Air
Las Vegas — Knoxville
8h 48m
including layover
Find flight
from$249
08:40 — 16:54
08:40 — 11:23 UA215 United Airlines
Houston — Chicago
2h 47m stop
14:10 — 16:54 UA5379 United Airlines
Chicago — Knoxville
7h 14m
including layover
Find flight
from$299
09:00 — 16:14
09:00 — 12:39 NK910 Spirit Airlines
Houston — Miami
1h 26m stop
14:05 — 16:14 G41402 Allegiant Air
Miami — Knoxville
6h 14m
including layover
Find flight
from$234
12:10 — 23:00
12:10 — 14:55 UA1168 United Airlines
Houston — Chicago
5h 20m stop
20:15 — 23:00 UA1871 United Airlines
Chicago — Knoxville
9h 50m
including layover
Find flight
from$412
12:28 — 21:36
12:28 — 16:02 NK198 Spirit Airlines
Houston — Sanford
3h 56m stop
19:58 — 21:36 G41423 Allegiant Air
Sanford — Knoxville
8h 8m
including layover
Find flight
from$150
14:20 — 23:00
14:20 — 17:06 UA2097 United Airlines
Houston — Chicago
3h 9m stop
20:15 — 23:00 UA1871 United Airlines
Chicago — Knoxville
7h 40m
including layover
Find flight
from$385
14:46 — 14:58
+1 day
14:46 — 16:28 UA241 United Airlines
Houston — Denver
17h 42m stop
10:10 — 14:58 UA2420 United Airlines
Denver — Knoxville
23h 12m
including layover
Find flight
from$346
16:20 — 23:00
16:20 — 19:05 UA2659 United Airlines
Houston — Chicago
1h 10m stop
20:15 — 23:00 UA1871 United Airlines
Chicago — Knoxville
5h 40m
including layover
Find flight
from$288
18:45 — 16:54
+1 day
18:45 — 21:30 UA787 United Airlines
Houston — Chicago
16h 40m stop
14:10 — 16:54 UA3592 United Airlines
Chicago — Knoxville
21h 9m
including layover
Find flight
from$261
18:45 — 23:00
+1 day
18:45 — 21:30 UA787 United Airlines
Houston — Chicago
22h 45m stop
20:15 — 23:00 UA1871 United Airlines
Chicago — Knoxville
27h 15m
including layover
Find flight
from$261
20:17 — 16:54
+1 day
20:17 — 22:58 UA321 United Airlines
Houston — Chicago
15h 12m stop
14:10 — 16:54 UA3592 United Airlines
Chicago — Knoxville
19h 37m
including layover
Find flight
from$261
20:17 — 23:00
+1 day
20:17 — 22:58 UA321 United Airlines
Houston — Chicago
21h 17m stop
20:15 — 23:00 UA1871 United Airlines
Chicago — Knoxville
25h 43m
including layover
Find flight
from$261
21:38 — 16:54
+1 day
21:38 — 00:15 UA1692 United Airlines
Houston — Chicago
13h 55m stop
14:10 — 16:54 UA3592 United Airlines
Chicago — Knoxville
18h 16m
including layover
Find flight
from$261
21:38 — 23:00
+1 day
21:38 — 00:15 UA1692 United Airlines
Houston — Chicago
20h stop
20:15 — 23:00 UA1871 United Airlines
Chicago — Knoxville
24h 22m
including layover
Find flight
from$261
22:20 — 14:58
+1 day
22:20 — 23:59 UA1338 United Airlines
Houston — Denver
10h 11m stop
10:10 — 14:58 UA2420 United Airlines
Denver — Knoxville
15h 38m
including layover
Find flight
from$309
23:13 — 16:50
+1 day
23:13 — 00:50 F94855 Frontier Airlines
Houston — Denver
11h 8m stop
11:58 — 16:50 F92374 Frontier Airlines
Denver — Knoxville
16h 37m
including layover
Find flight
from$265
07:00 — 21:36
07:00 — 11:05 NK222 Spirit Airlines
Houston — Baltimore
1h 7m stop
12:12 — 14:40 NK1855 Spirit Airlines
Baltimore — Sanford
5h 18m stop
19:58 — 21:36 G41423 Allegiant Air
Sanford — Knoxville
13h 36m
including layover
Find flight
from$186
07:00 — 18:20
07:00 — 11:05 NK222 Spirit Airlines
Houston — Baltimore
1h 7m stop
12:12 — 14:40 NK1855 Spirit Airlines
Baltimore — Orlando
1h 49m stop
16:29 — 18:20 G43054 Allegiant Air
Orlando — Knoxville
10h 20m
including layover
Find flight
from$195
19:55 — 12:38
+1 day
19:55 — 23:10 NK3126 Spirit Airlines
Houston — Tampa
6h 20m stop
05:30 — 06:33 NK1955 Spirit Airlines
Tampa — Miami
3h 56m stop
10:29 — 12:38 G41428 Allegiant Air
Miami — Knoxville
15h 43m
including layover
Find flight
from$213
*Departure and arrival times - local. Updated on February 5, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Houston to Knoxville depends on and how to choose the most interesting flight option for you.

Distance between Houston and Knoxville is 1257 miles. Time difference between the cities is 1h. Airplanes depart 05:30 to 23:13 from 15 Houston airports and arrive 05:30 to 23:13 to 1 Knoxville airport. Average flight time is 14h 9m.

  • The fastest flight 5h 40m
  • Average flight time 14h 9m
  • The earliest flight 05:30
  • The latest flight 23:13
  • Distance 782 ml

The cheapest months to travel to Knoxville are february (from 150 $).

What is the lowest airfare Houston to Knoxville?

The cheapest plane ticket found by our users is $150. This airfare is for economy class on one-way NK198 flight by Spirit Airlines for February 21, 2025 which leaves George Bush in Houston at 12:28 am and arrives at Knoxville Mc Ghee Tyson at 21:36.

Economy class
$150
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Business class
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First class
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Popular Airlines on the Route

The flight Houston — Knoxville is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 1 departures per week at the price of from $ 265 . And the most expensive tickets are offered by Spirit Airlines airline - from $ 619.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 42 flights with layovers on the route. The fastest connecting flight is UA2659 by United Airlines takes 5h 40m and the cheapest is NK198 by Spirit Airlines for $150.

  • F9 - Frontier Airlines
    from $265
    Find
  • UA - United Airlines
    from $261
    Find
  • NK - Spirit Airlines
    from $150
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See more connecting flights

Airports

You can fly from Houston to Knoxville from 15 airports (Ellington Field, West Houston, Hobby, Park Ten Heliport, Andrau Airpark, George Bush, Greenway Plaza H/P, David Wayne Hooks, Transco Twr Galleria, Westchase Hilton H/P, Spaceland, Woodlawns, Marriot Astrodome Heliport, Central Bus. District, Houston Municipal).

Houston airports

  • Ellington Field-EFD
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  • West Houston-IWS
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  • Hobby-HOU
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  • Park Ten Heliport-JPT
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  • Andrau Airpark-AAP
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  • George Bush-IAH
    from $150
    Find
  • Greenway Plaza H/P-JGP
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  • David Wayne Hooks-DWH
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  • Transco Twr Galleria-JGQ
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  • Westchase Hilton H/P-JWH
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  • Spaceland-SPX
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  • Woodlawns-JWL
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  • Marriot Astrodome Heliport-JMA
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  • Central Bus. District-JDX
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  • Houston Municipal-SGR
    Find

Knoxville airports

  • Mc Ghee Tyson-TYS
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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