Cheap Flights from Houston, TX to Knoxville, TN from $53
Return flight: Knoxville – Houston
On Cheapflightsplus.com you will find 8 direct and 560 connecting flights from Houston to Knoxville. You can compare airfare deals from 5 airlines and multiple travel sites from $53, book and save on cheap plane tickets and last minute offers. Also check out HOU-TYS flight schedule to find best flight time, convenient departure and arrival airports.
Find One-Way and Round-Trip Houston to Knoxville Flight Deals
To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights».
To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight.
Cheapest flights in November: $53 (one-way), $91 (round-trip).
Direct flights
Check prices for return flight
Best Flights from Houston to Knoxville Today
Take a look at the list of non stop flights and flights with layovers from Houston to Knoxville with the lowest price of $53. The fastest direct flight takes 2h 1m and the fastest connecting – 5h 21m.
| Price | Departure | Arrival | Flight Duration | Airline | Flight |
|---|---|---|---|---|---|
| from $53 | 20:02 Houston Hobby | 23:03 Knoxville Mc Ghee Tyson | 2h 1m | Allegiant Air | G43027 |
| from $53 | 19:01 Houston Hobby | 22:03 Knoxville Mc Ghee Tyson | 2h 2m | Allegiant Air | G41427 |
| from $275 | 16:20 Houston George Bush | 19:34 Knoxville Mc Ghee Tyson | 2h 14m | United Airlines | UA4900 |
| from $94 | 17:53 Houston George Bush | 12:39+1 день Knoxville Mc Ghee Tyson | 17h 46m layover 13h 58m - Clearwater | Spirit Airlines | NK2024 G43051 |
| from $116 | 20:44 Houston George Bush | 08:19+1 день Knoxville Mc Ghee Tyson | 10h 35m layover 5h 55m - Miami | Spirit Airlines | NK2067 G4499 |
| from $116 | 19:44 Houston George Bush | 08:19+1 день Knoxville Mc Ghee Tyson | 11h 35m layover 6h 56m - Miami | Spirit Airlines | NK2085 G4499 |
| from $116 | 05:26 Houston George Bush | 08:19+1 день Knoxville Mc Ghee Tyson | 25h 53m layover 21h 21m - Miami | Spirit Airlines | NK2677 G4499 |
| from $117 | 05:20 Houston George Bush | 20:41 Knoxville Mc Ghee Tyson | 14h 21m layover 10h 16m - Sanford | Spirit Airlines | NK1571 G42839 |
| from $123 | 06:00 Houston George Bush | 16:29 Knoxville Mc Ghee Tyson | 9h 29m layover 4h 1m - Denver | Frontier Airlines | F93229 F92374 |
| from $129 | 20:05 Houston George Bush | 13:23+1 день Knoxville Mc Ghee Tyson | 16h 18m layover 12h 19m - Clearwater | Spirit Airlines | NK3126 G41417 |
| from $130 | 05:10 Houston George Bush | 16:47 Knoxville Mc Ghee Tyson | 10h 37m layover 6h 0m - Washington D.C. | Spirit Airlines | NK2569 G41398 |
| from $130 | 22:04 Houston George Bush | 16:29+1 день Knoxville Mc Ghee Tyson | 17h 25m layover 11h 53m - Denver | Frontier Airlines | F93227 F92374 |
| from $131 | 06:30 Houston George Bush | 16:47 Knoxville Mc Ghee Tyson | 9h 17m layover 4h 45m - Washington D.C. | Spirit Airlines | NK2174 G41398 |
| from $134 | 05:20 Houston George Bush | 15:06 Knoxville Mc Ghee Tyson | 8h 46m layover 4h 41m - Sanford | Spirit Airlines | NK1571 G41322 |
| from $135 | 18:44 Houston George Bush | 11:50+1 день Knoxville Mc Ghee Tyson | 16h 6m layover 10h 39m - Newark | Spirit Airlines | NK2643 G41405 |
| from $114 | 13:42 Houston George Bush | 12:39+1 день Knoxville Mc Ghee Tyson | 21h 57m layover 0h 50m - Baltimore 13h 54m - Clearwater | Spirit Airlines | NK2399 NK2447 G43051 |
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on August 08, 2025
Flight Schedule Houston (Texas) to Knoxville (Tennessee)
Full flight schedule will help you in detecting at what time planes fly from Houston to Knoxville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
| Departure | Arrival | Flight Details | Flight Duration | Price |
|---|---|---|---|---|
|
10:01 — 13:24
|
10:01 — 13:24
UA4887
United Airlines
Houston — Knoxville
|
2h 23m |
Find flight
from$276 |
|
|
11:55 — 15:18
|
11:55 — 15:18
UA6017
United Airlines
Houston — Knoxville
|
2h 23m |
Find flight
from$275 |
|
|
11:55 — 15:18
|
11:55 — 15:18
UA6093
United Airlines
Houston — Knoxville
|
2h 23m |
Find flight
from$276 |
|
|
14:20 — 17:37
|
14:20 — 17:37
UA4890
United Airlines
Houston — Knoxville
|
2h 17m |
Find flight
from$275 |
|
|
16:20 — 19:34
|
16:20 — 19:34
UA4900
United Airlines
Houston — Knoxville
|
2h 14m |
Find flight
from$275 |
|
|
19:01 — 22:03
|
19:01 — 22:03
G41427
Allegiant Air
Houston — Knoxville
|
2h 2m |
Find flight
from$53 |
|
|
20:02 — 23:03
|
20:02 — 23:03
G43027
Allegiant Air
Houston — Knoxville
|
2h 1m |
Find flight
from$53 |
|
|
20:05 — 23:19
|
20:05 — 23:19
UA4810
United Airlines
Houston — Knoxville
|
2h 14m |
Find flight
from$275 |
|
|
05:20 — 20:41
|
05:20 — 08:50
NK1571
Spirit Airlines
Houston — Sanford
10h 16m stop
19:06 — 20:41
G42839
Allegiant Air
Sanford — Knoxville
|
14h 21m including layover |
Find flight
from$117 |
|
|
05:26 — 08:19
+1 day
|
05:26 — 08:54
NK2677
Spirit Airlines
Houston — Miami
21h 21m stop
06:15 — 08:19
G4499
Allegiant Air
Miami — Knoxville
|
25h 53m including layover |
Find flight
from$116 |
|
|
06:00 — 16:29
|
06:00 — 07:50
F93229
Frontier Airlines
Houston — Denver
4h 1m stop
11:41 — 16:35
F92374
Frontier Airlines
Denver — Knoxville
|
9h 29m including layover |
Find flight
from$123 |
|
|
06:30 — 16:47
|
06:30 — 10:28
NK2174
Spirit Airlines
Houston — Washington D.C.
4h 45m stop
15:13 — 16:47
G41398
Allegiant Air
Washington D.C. — Knoxville
|
9h 17m including layover |
Find flight
from$131 |
|
|
17:53 — 12:39
+1 day
|
17:53 — 21:01
NK2024
Spirit Airlines
Houston — Clearwater
13h 58m stop
10:59 — 12:39
G43051
Allegiant Air
Clearwater — Knoxville
|
17h 46m including layover |
Find flight
from$94 |
|
|
17:53 — 22:38
+1 day
|
17:53 — 21:01
NK2024
Spirit Airlines
Houston — Clearwater
23h 57m stop
20:58 — 22:38
G41432
Allegiant Air
Clearwater — Knoxville
|
27h 45m including layover |
Find flight
from$94 |
|
|
18:35 — 16:12
+1 day
|
18:18 — 21:02
SY682
Sun Country Airlines
Houston — Minneapolis
15h 50m stop
13:08 — 16:11
G43063
Allegiant Air
Minneapolis — Knoxville
|
20h 37m including layover |
Find flight
from$148 |
|
|
18:44 — 11:50
+1 day
|
18:44 — 23:16
NK2643
Spirit Airlines
Houston — Newark
10h 39m stop
09:55 — 11:55
G41405
Allegiant Air
Newark — Knoxville
|
16h 6m including layover |
Find flight
from$135 |
|
|
19:15 — 22:17
+1 day
|
19:15 — 22:17
NK2024
Spirit Airlines
Houston — Clearwater
22h 20m stop
20:37 — 22:17
G43035
Allegiant Air
Clearwater — Knoxville
|
26h 2m including layover |
Find flight
from$113 |
|
|
20:44 — 08:19
+1 day
|
20:44 — 00:20
NK2067
Spirit Airlines
Houston — Miami
5h 55m stop
06:15 — 08:19
G4499
Allegiant Air
Miami — Knoxville
|
10h 35m including layover |
Find flight
from$116 |
|
|
21:06 — 11:11
+1 day
|
17:53 — 21:01
NK2024
Spirit Airlines
Houston — Clearwater
9h 32m stop
15:22 — 17:03
G43046
Allegiant Air
Clearwater — Knoxville
|
13h 5m including layover |
Find flight
from$139 |
|
|
21:06 — 22:56
+1 day
|
21:06 — 23:59
NK2024
Spirit Airlines
Houston — Clearwater
21h 17m stop
21:16 — 22:56
G43047
Allegiant Air
Clearwater — Knoxville
|
24h 50m including layover |
Find flight
from$153 |
|
|
22:04 — 16:29
+1 day
|
21:05 — 23:02
F93227
Frontier Airlines
Houston — Denver
11h 53m stop
11:41 — 16:35
F92374
Frontier Airlines
Denver — Knoxville
|
17h 25m including layover |
Find flight
from$130 |
|
|
07:05 — 22:17
|
07:05 — 10:09
NK2170
Spirit Airlines
Houston — Atlanta
4h 36m stop
14:45 — 16:08
NK2468
Spirit Airlines
Atlanta — Clearwater
4h 29m stop
20:37 — 22:17
G43035
Allegiant Air
Clearwater — Knoxville
|
14h 12m including layover |
Find flight
from$153 |
|
|
07:05 — 11:42
+1 day
|
07:05 — 10:09
NK2170
Spirit Airlines
Houston — Atlanta
8h 11m stop
18:20 — 19:55
SY356
Sun Country Airlines
Atlanta — Minneapolis
12h 39m stop
08:34 — 11:42
G41428
Allegiant Air
Minneapolis — Knoxville
|
27h 37m including layover |
Find flight
from$161 |
|
|
09:23 — 20:31
+1 day
|
09:23 — 12:08
NK1145
Spirit Airlines
Houston — Chicago
4h 30m stop
16:38 — 20:27
NK529
Spirit Airlines
Chicago — Clearwater
22h 26m stop
18:53 — 20:31
G43061
Allegiant Air
Clearwater — Knoxville
|
34h 8m including layover |
Find flight
from$159 |
|
|
09:50 — 08:19
+1 day
|
09:50 — 13:34
NK2640
Spirit Airlines
Houston — Detroit
3h 44m stop
17:18 — 20:21
NK2903
Spirit Airlines
Detroit — Miami
9h 54m stop
06:15 — 08:19
G4499
Allegiant Air
Miami — Knoxville
|
21h 29m including layover |
Find flight
from$152 |
|
|
12:48 — 20:31
+1 day
|
12:48 — 15:35
NK1338
Spirit Airlines
Houston — Chicago
1h 3m stop
16:38 — 20:27
NK529
Spirit Airlines
Chicago — Clearwater
22h 26m stop
18:53 — 20:31
G43061
Allegiant Air
Clearwater — Knoxville
|
30h 43m including layover |
Find flight
from$159 |
|
|
13:42 — 12:39
+1 day
|
13:42 — 17:45
NK2399
Spirit Airlines
Houston — Baltimore
50m stop
18:35 — 21:05
NK2447
Spirit Airlines
Baltimore — Clearwater
13h 54m stop
10:59 — 12:39
G43051
Allegiant Air
Clearwater — Knoxville
|
21h 57m including layover |
Find flight
from$114 |
|
|
13:51 — 08:19
+1 day
|
13:51 — 16:57
NK2571
Spirit Airlines
Houston — Atlanta
2h 19m stop
19:16 — 21:11
NK2061
Spirit Airlines
Atlanta — Miami
9h 4m stop
06:15 — 08:19
G4499
Allegiant Air
Miami — Knoxville
|
17h 28m including layover |
Find flight
from$136 |
|
|
14:18 — 11:18
+1 day
|
14:18 — 17:52
NK1375
Spirit Airlines
Houston — Orlando
1h 48m stop
19:40 — 20:53
NK675
Spirit Airlines
Orlando — Miami
12h 22m stop
09:15 — 11:18
G4531
Allegiant Air
Miami — Knoxville
|
20h including layover |
Find flight
from$163 |
|
|
14:33 — 21:47
+1 day
|
14:33 — 17:42
G4263
Allegiant Air
Houston — Fletcher
19h 29m stop
13:11 — 13:40
G41852
Allegiant Air
Fletcher — Fort Walton Beach
5h 46m stop
19:26 — 21:47
G43025
Allegiant Air
Fort Walton Beach — Knoxville
|
30h 14m including layover |
Find flight
from$163 |
|
|
15:49 — 08:19
+1 day
|
15:49 — 17:06
NK2065
Spirit Airlines
Houston — New Orleans
2h 59m stop
20:05 — 23:00
NK2003
Spirit Airlines
New Orleans — Miami
7h 15m stop
06:15 — 08:19
G4499
Allegiant Air
Miami — Knoxville
|
15h 30m including layover |
Find flight
from$136 |
|
|
15:50 — 20:31
+1 day
|
15:50 — 19:31
NK910
Spirit Airlines
Houston — Miami
2h 28m stop
21:59 — 23:06
NK1954
Spirit Airlines
Miami — Clearwater
19h 47m stop
18:53 — 20:31
G43061
Allegiant Air
Clearwater — Knoxville
|
27h 41m including layover |
Find flight
from$159 |
|
*Departure and arrival times - local. Updated on August 8, 2025
Flight Information
Below we will explain in detail what the flights cost on the destination from Houston to Knoxville depends on and how to choose the most interesting flight option for you.
Distance between Houston and Knoxville is 1257 miles. Time difference between the cities is 1h. Airplanes depart 05:00 to 22:05 from 15 Houston airports and arrive 05:00 to 22:05 to 1 Knoxville airport. Average flight time is 2h 16m.
- The fastest flight 2h 1m
- Average flight time 2h 16m
- The earliest flight 05:00
- The latest flight 22:05
- Distance 782 ml
The cheapest months to travel to Knoxville are june (from 53 $), august (from 53 $), may (from 91 $).
The most expensive months are january (from 696 $), december (from 564 $), september (from 159 $).
What is the lowest airfare Houston to Knoxville?
The cheapest plane ticket found by our users is $53. This airfare is for economy class on one-way G41427 flight by Allegiant Air for June 6, 2025 which leaves Hobby in Houston at 19:01 am and arrives at Knoxville Mc Ghee Tyson at 22:03.
Economy class
$53
Business class
?
First class
?
Popular Airlines on the Route
The flight Houston — Knoxville is served by 5 regular airlines and 4 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 2 departures per week at the price of from $ 123 . And the most expensive tickets are offered by United Airlines airline - from $ 736.
Direct flights
There are 8 nonstop flights on the route. The fastest direct flight is G43027 by Allegiant Air takes 2h 1m and the cheapest is G41427 by Allegiant Air for $53.
- UA - United Airlinesfrom $275Find
- G4 - Allegiant Airfrom $53Find
See more direct flights
Connecting Flights
There are 560 flights with layovers on the route. The fastest connecting flight is UA2182 by United Airlines takes 5h 21m and the cheapest is G41427 by Allegiant Air for $94.
- F9 - Frontier Airlinesfrom $123Find
- SY - Sun Country Airlinesfrom $144Find
- UA - United Airlinesfrom $279Find
- NK - Spirit Airlinesfrom $94Find
- G4 - Allegiant Airfrom $146Find
See more connecting flights
Airports
You can fly from Houston to Knoxville from 15 airports (Ellington Field, West Houston, Hobby, Park Ten Heliport, Andrau Airpark, George Bush, Greenway Plaza H/P, David Wayne Hooks, Transco Twr Galleria, Westchase Hilton H/P, Spaceland, Woodlawns, Marriot Astrodome Heliport, Central Bus. District, Houston Municipal).
Houston airports
- Ellington Field-EFDFind
- West Houston-IWSFind
- Hobby-HOUfrom $53Find
- Park Ten Heliport-JPTFind
- Andrau Airpark-AAPFind
- George Bush-IAHfrom $94Find
- Greenway Plaza H/P-JGPFind
- David Wayne Hooks-DWHFind
- Transco Twr Galleria-JGQFind
- Westchase Hilton H/P-JWHFind
- Spaceland-SPXFind
- Woodlawns-JWLFind
- Marriot Astrodome Heliport-JMAFind
- Central Bus. District-JDXFind
- Houston Municipal-SGRFind
Knoxville airports
- Mc Ghee Tyson-TYSFind
Airplanes
There are flights to Knoxville from Houston by 5 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Houston
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Top International Destinations from Houston
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
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How to book a plane ticket yourself?
- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
- Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
- Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
- Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
- That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
To find a plane ticket, please select dates.