Cheap Flights from Knoxville, TN to Panama City from $251

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On Cheapflightsplus.com you will find 138 connecting flights from Knoxville to Panama City. You can compare airfare deals from 2 airlines and multiple travel sites from $251, book and save on cheap plane tickets and last minute offers. Also check out TYS-PTY flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Knoxville to Panama City Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $251 (one-way), $430 (round-trip).

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Best Flights from Knoxville to Panama City Today

Take a look at the list of non stop flights and flights with layovers from Knoxville to Panama City with the lowest price of $251. Take a look at the list of flights with layovers from Knoxville to Panama City from $251. There’re no direct flights. The fastest connecting flight – 7h 37m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $251 Find flight	08:15 Knoxville Mc Ghee Tyson	14:45+1 день Panama City Tocumen	30h 30m layover 19h 40m - New York 2h 0m - San Salvador	Allegiant Air	G41396 AV569 AV317
from $269 Find flight	11:00 Knoxville Mc Ghee Tyson	10:25+1 день Panama City Tocumen	23h 25m layover 9h 48m - Miami 6h 38m - San Salvador	Allegiant Air	G41415 NK1031 AV323
from $269 Find flight	11:00 Knoxville Mc Ghee Tyson	14:45+1 день Panama City Tocumen	27h 45m layover 9h 48m - Miami 10h 58m - San Salvador	Allegiant Air	G41415 NK1031 AV317
from $272 Find flight	17:15 Knoxville Mc Ghee Tyson	12:35+1 день Panama City Tocumen	19h 20m layover 3h 33m - Miami 9h 16m - San Jose	Allegiant Air	G43477 NK1755 AV643
from $277 Find flight	17:15 Knoxville Mc Ghee Tyson	21:00+1 день Panama City Tocumen	27h 45m layover 18h 38m - Miami 1h 21m - Bogota	Allegiant Air	G43477 AV37 AV56
from $284 Find flight	21:59 Knoxville Mc Ghee Tyson	21:00+1 день Panama City Tocumen	23h 1m layover 8h 57m - Orlando 6h 30m - Bogota	Allegiant Air	G41417 NK1921 AV56
from $284 Find flight	21:59 Knoxville Mc Ghee Tyson	00:20+2 дня Panama City Tocumen	26h 21m layover 8h 57m - Orlando 9h 45m - Bogota	Allegiant Air	G41417 NK1921 AV40
from $287 Find flight	11:00 Knoxville Mc Ghee Tyson	12:35+1 день Panama City Tocumen	25h 35m layover 9h 48m - Miami 9h 16m - San Jose	Allegiant Air	G41415 NK1755 AV643
from $287 Find flight	21:59 Knoxville Mc Ghee Tyson	06:36+2 дня Panama City Tocumen	32h 37m layover 8h 57m - Orlando 15h 57m - Bogota	Allegiant Air	G41417 NK1921 CM837
from $291 Find flight	17:56 Knoxville Mc Ghee Tyson	12:35+2 дня Panama City Tocumen	42h 39m layover 13h 23m - Orlando 22h 57m - San Jose	Allegiant Air	G43038 NK1309 AV643
from $310 Find flight	17:15 Knoxville Mc Ghee Tyson	14:40+1 день Panama City Tocumen	21h 25m layover 2h 54m - Miami 11h 30m - Medellin	Allegiant Air	G43477 NK973 AV322
from $319 Find flight	17:15 Knoxville Mc Ghee Tyson	16:30+1 день Panama City Tocumen	23h 15m layover 11h 9m - Miami 4h 12m - Bogota	Allegiant Air	G43477 NK862 AV60
from $326 Find flight	11:00 Knoxville Mc Ghee Tyson	14:40+1 день Panama City Tocumen	27h 40m layover 9h 9m - Miami 11h 30m - Medellin	Allegiant Air	G41415 NK973 AV322
from $331 Find flight	10:00 Knoxville Mc Ghee Tyson	10:25+1 день Panama City Tocumen	24h 25m layover 4h 59m - Houston 12h 5m - San Salvador	Allegiant Air	G43020 AV425 AV323
from $333 Find flight	17:15 Knoxville Mc Ghee Tyson	12:59+1 день Panama City Tocumen	19h 44m layover 2h 54m - Miami 9h 35m - Medellin	Allegiant Air	G43477 NK973 CM856
from $336 Find flight	21:59 Knoxville Mc Ghee Tyson	19:15+1 день Panama City Tocumen	21h 16m layover 10h 22m - Orlando 4h 7m - Medellin	Allegiant Air	G41417 NK1473 AV316

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on November 18, 2024

Flight Schedule Knoxville (Tennessee) to Panama City

Full flight schedule will help you in detecting at what time planes fly from Knoxville to Panama City. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
06:20 — 17:08	06:20 — 07:56 G43048 Allegiant Air Knoxville — Orlando 5h 43m stop 13:39 — 17:08 CM479 Compania Panamena de Aviacion Orlando — Panama City	10h 48m including layover	Find flight from$764
06:30 — 17:08	06:30 — 08:08 G43032 Allegiant Air Knoxville — Orlando 5h 31m stop 13:39 — 17:08 CM479 Compania Panamena de Aviacion Orlando — Panama City	10h 38m including layover	Find flight from$640
07:05 — 14:45	07:05 — 08:50 UA4913 United Airlines Knoxville — Houston 44m stop 09:34 — 14:45 UA1916 United Airlines Houston — Panama City	7h 40m including layover	Find flight from$674
07:30 — 19:28	07:30 — 09:08 G41417 Allegiant Air Knoxville — Orlando 6h 51m stop 15:59 — 19:28 CM459 Compania Panamena de Aviacion Orlando — Panama City	11h 58m including layover	Find flight from$639
09:25 — 19:38	09:25 — 11:06 UA4841 United Airlines Knoxville — Houston 3h 21m stop 14:27 — 19:38 UA1034 United Airlines Houston — Panama City	10h 13m including layover	Find flight from$674
09:25 — 14:45 +1 day	09:25 — 11:06 UA4841 United Airlines Knoxville — Houston 22h 28m stop 09:34 — 14:45 UA1916 United Airlines Houston — Panama City	29h 20m including layover	Find flight from$683
14:08 — 20:19 +1 day	14:08 — 16:20 G43040 Allegiant Air Knoxville — Miami 24h 49m stop 17:09 — 20:19 CM266 Compania Panamena de Aviacion Miami — Panama City	30h 11m including layover	Find flight from$543
15:04 — 18:00 +1 day	15:04 — 16:55 G41430 Allegiant Air Knoxville — Tampa 21h 37m stop 14:32 — 18:00 CM394 Compania Panamena de Aviacion Tampa — Panama City	26h 56m including layover	Find flight from$551
16:13 — 10:37 +1 day	16:13 — 17:51 G43062 Allegiant Air Knoxville — Orlando 13h 17m stop 07:08 — 10:37 CM435 Compania Panamena de Aviacion Orlando — Panama City	18h 24m including layover	Find flight from$646
16:49 — 10:37 +1 day	16:49 — 18:25 G4555 Allegiant Air Knoxville — Orlando 12h 43m stop 07:08 — 10:37 CM435 Compania Panamena de Aviacion Orlando — Panama City	17h 48m including layover	Find flight from$799
18:08 — 18:00 +1 day	18:08 — 19:54 G41439 Allegiant Air Knoxville — Tampa 18h 38m stop 14:32 — 18:00 CM394 Compania Panamena de Aviacion Tampa — Panama City	23h 52m including layover	Find flight from$689
18:48 — 20:00 +1 day	18:48 — 20:25 G43132 Allegiant Air Knoxville — Austin 18h 4m stop 14:29 — 20:00 CM716 Compania Panamena de Aviacion Austin — Panama City	25h 12m including layover	Find flight from$897
20:49 — 18:00 +1 day	20:49 — 22:40 G43645 Allegiant Air Knoxville — Tampa 15h 52m stop 14:32 — 18:00 CM394 Compania Panamena de Aviacion Tampa — Panama City	21h 11m including layover	Find flight from$546
08:15 — 14:45 +1 day	08:15 — 10:05 G41396 Allegiant Air Knoxville — New York 19h 40m stop 05:45 — 09:50 AV569 Avianca New York — San Salvador 2h stop 11:50 — 14:45 AV317 Avianca San Salvador — Panama City	30h 30m including layover	Find flight from$251
08:15 — 10:25 +1 day	08:15 — 10:05 G41396 Allegiant Air Knoxville — New York 16h 30m stop 02:35 — 06:30 AV571 Avianca New York — San Salvador 1h stop 07:30 — 10:25 AV323 Avianca San Salvador — Panama City	26h 10m including layover	Find flight from$258
10:00 — 10:25 +1 day	10:00 — 11:31 G43020 Allegiant Air Knoxville — Houston 4h 59m stop 16:30 — 19:25 AV425 Avianca Houston — San Salvador 12h 5m stop 07:30 — 10:25 AV323 Avianca San Salvador — Panama City	24h 25m including layover	Find flight from$331
10:00 — 14:45 +1 day	10:00 — 11:31 G43020 Allegiant Air Knoxville — Houston 4h 59m stop 16:30 — 19:25 AV425 Avianca Houston — San Salvador 16h 25m stop 11:50 — 14:45 AV317 Avianca San Salvador — Panama City	28h 45m including layover	Find flight from$348
11:00 — 10:25 +1 day	11:00 — 13:17 G41415 Allegiant Air Knoxville — Miami 9h 48m stop 23:05 — 00:52 NK1031 Spirit Airlines Miami — San Salvador 6h 38m stop 07:30 — 10:25 AV323 Avianca San Salvador — Panama City	23h 25m including layover	Find flight from$269
11:00 — 14:45 +1 day	11:00 — 13:17 G41415 Allegiant Air Knoxville — Miami 9h 48m stop 23:05 — 00:52 NK1031 Spirit Airlines Miami — San Salvador 10h 58m stop 11:50 — 14:45 AV317 Avianca San Salvador — Panama City	27h 45m including layover	Find flight from$269
12:25 — 20:19 +1 day	12:25 — 14:08 G43049 Allegiant Air Knoxville — Tampa 20h 52m stop 11:00 — 12:15 3M59 Gulfstream International Airlines Tampa — Miami 4h 47m stop 17:02 — 20:19 CM266 Compania Panamena de Aviacion Miami — Panama City	31h 54m including layover	Find flight from$348
12:25 — 21:00 +1 day	12:25 — 14:03 G41420 Allegiant Air Knoxville — Orlando 18h 43m stop 08:46 — 12:49 NK1921 Spirit Airlines Orlando — Bogota 6h 26m stop 19:15 — 21:00 AV56 Avianca Bogota — Panama City	32h 35m including layover	Find flight from$383
13:41 — 19:15 +1 day	13:41 — 15:58 G41416 Allegiant Air Knoxville — Miami 18h 47m stop 10:45 — 14:17 NK237 Spirit Airlines Miami — Medellin 3h 43m stop 18:00 — 19:15 AV316 Avianca Medellin — Panama City	29h 34m including layover	Find flight from$359
13:50 — 12:35 +2 days	13:50 — 15:39 G43053 Allegiant Air Knoxville — Orlando 19h 46m stop 11:25 — 13:40 NK1309 Spirit Airlines Orlando — San Jose 20h 35m stop 10:15 — 12:35 AV643 Avianca San Jose — Panama City	46h 45m including layover	Find flight from$346
17:15 — 12:35 +1 day	17:15 — 19:32 G43477 Allegiant Air Knoxville — Miami 3h 33m stop 23:05 — 00:59 NK1755 Spirit Airlines Miami — San Jose 9h 16m stop 10:15 — 12:35 AV643 Avianca San Jose — Panama City	19h 20m including layover	Find flight from$272
17:15 — 21:00 +1 day	17:15 — 19:32 G43477 Allegiant Air Knoxville — Miami 18h 38m stop 14:10 — 17:54 AV37 Avianca Miami — Bogota 1h 21m stop 19:15 — 21:00 AV56 Avianca Bogota — Panama City	27h 45m including layover	Find flight from$277
21:59 — 21:00 +1 day	21:59 — 23:43 G41417 Allegiant Air Knoxville — Orlando 8h 57m stop 08:40 — 12:45 NK1921 Spirit Airlines Orlando — Bogota 6h 30m stop 19:15 — 21:00 AV56 Avianca Bogota — Panama City	23h 1m including layover	Find flight from$284
21:59 — 00:20 +2 days	21:59 — 23:43 G41417 Allegiant Air Knoxville — Orlando 8h 57m stop 08:40 — 12:45 NK1921 Spirit Airlines Orlando — Bogota 9h 45m stop 22:30 — 00:20 AV40 Avianca Bogota — Panama City	26h 21m including layover	Find flight from$284

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on November 18, 2024

Flight Information

Below we will explain in detail what the flights cost on the destination from Knoxville to Panama City depends on and how to choose the most interesting flight option for you.

Distance between Knoxville and Panama City is 3010 miles. Time difference between the cities is 0h. Airplanes depart 06:00 to 21:59 from 1 Knoxville airport and arrive 06:00 to 21:59 to 2 Panama City airports. Average flight time is 23h 58m.

The fastest flight 7h 37m
Average flight time 23h 58m
The earliest flight 06:00
The latest flight 21:59
Distance 1871 ml

The cheapest months to travel to Panama City are february (from 251 $), january (from 269 $), december (from 331 $).

The most expensive months are november (from 456 $), december (from 331 $), january (from 269 $).

What is the lowest airfare Knoxville to Panama City?

The cheapest plane ticket found by our users is $251. This airfare is for economy class on one-way G41396 flight by Allegiant Air for February 21, 2025 which leaves Mc Ghee Tyson in Knoxville at 08:15 am and arrives at Panama City Tocumen at 14:45.

Economy class

$251

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Business class

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First class

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Popular Airlines on the Route

The flight Knoxville — Panama City is served by 2 regular airlines and 1 low-cost airline. Most of the flights on this route are operated by United Airlines - 6 departures per week at the price of from $ 674 . And the most expensive tickets are offered by United Airlines airline - from $ 1509.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 138 flights with layovers on the route. The fastest connecting flight is G41437 by Allegiant Air takes 7h 37m and the cheapest is G41396 by Allegiant Air for $251.

UA - United Airlines

from $674

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G4 - Allegiant Air

from $251

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Airports

You can fly from Knoxville to Panama City from 1 airports (Mc Ghee Tyson).

Knoxville airports

Mc Ghee Tyson-TYS

from $251
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Panama City airports

Tocumen-PTY

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Paitilla-PAC

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Airplanes

There are flights to Panama City from Knoxville by 2 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Knoxville

You may also consider searching for discounted plane tickets to some other popular places from Knoxville within United States.

Knoxville — Tampa

from $80

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Knoxville — Houston

from $54

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Knoxville — New Orleans

from $56

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Knoxville — Orlando

from $73

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Knoxville — Chicago

from $76

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Knoxville — Boston

from $69

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Knoxville — San Francisco

from $78

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Knoxville — Las Vegas

from $74

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Knoxville — Key West

from $64

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Knoxville — Seattle

from $73

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Top International Destinations from Knoxville

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Knoxville — Cancun

from $69

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Knoxville — Panama City

from $61

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Knoxville — Manchester

from $64

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How to book a plane ticket yourself?

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