Cheap Flights from Knoxville, TN to Panama City from $251
Return flight: Panama City – Knoxville
On Cheapflightsplus.com you will find 58 connecting flights from Knoxville to Panama City. You can compare airfare deals from 1 airlines and multiple travel sites from $251, book and save on cheap plane tickets and last minute offers. Also check out TYS-PTY flight schedule to find best flight time, convenient departure and arrival airports.
Find One-Way and Round-Trip Knoxville to Panama City Flight Deals
To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights».
To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight.
Cheapest flights in November: $251 (one-way), $430 (round-trip).
Direct flights
Check prices for return flight
Best Flights from Knoxville to Panama City Today
Take a look at the list of non stop flights and flights with layovers from Knoxville to Panama City with the lowest price of $251. Take a look at the list of flights with layovers from Knoxville to Panama City from $251. There’re no direct flights. The fastest connecting flight – 13h 19m.
| Price | Departure | Arrival | Flight Duration | Airline | Flight |
|---|---|---|---|---|---|
| from $251 | 08:15 Knoxville Mc Ghee Tyson | 14:45+1 день Panama City Tocumen | 30h 30m layover 19h 40m - New York 2h 0m - San Salvador | Allegiant Air | G41396 AV569 AV317 |
| from $269 | 11:00 Knoxville Mc Ghee Tyson | 10:25+1 день Panama City Tocumen | 23h 25m layover 9h 48m - Miami 6h 38m - San Salvador | Allegiant Air | G41415 NK1031 AV323 |
| from $269 | 11:00 Knoxville Mc Ghee Tyson | 14:45+1 день Panama City Tocumen | 27h 45m layover 9h 48m - Miami 10h 58m - San Salvador | Allegiant Air | G41415 NK1031 AV317 |
| from $272 | 17:15 Knoxville Mc Ghee Tyson | 12:35+1 день Panama City Tocumen | 19h 20m layover 3h 33m - Miami 9h 16m - San Jose | Allegiant Air | G43477 NK1755 AV643 |
| from $277 | 17:15 Knoxville Mc Ghee Tyson | 21:00+1 день Panama City Tocumen | 27h 45m layover 18h 38m - Miami 1h 21m - Bogota | Allegiant Air | G43477 AV37 AV56 |
| from $284 | 21:59 Knoxville Mc Ghee Tyson | 21:00+1 день Panama City Tocumen | 23h 1m layover 8h 57m - Orlando 6h 30m - Bogota | Allegiant Air | G41417 NK1921 AV56 |
| from $284 | 21:59 Knoxville Mc Ghee Tyson | 00:20+2 дня Panama City Tocumen | 26h 21m layover 8h 57m - Orlando 9h 45m - Bogota | Allegiant Air | G41417 NK1921 AV40 |
| from $287 | 11:00 Knoxville Mc Ghee Tyson | 12:35+1 день Panama City Tocumen | 25h 35m layover 9h 48m - Miami 9h 16m - San Jose | Allegiant Air | G41415 NK1755 AV643 |
| from $287 | 21:59 Knoxville Mc Ghee Tyson | 06:36+2 дня Panama City Tocumen | 32h 37m layover 8h 57m - Orlando 15h 57m - Bogota | Allegiant Air | G41417 NK1921 CM837 |
| from $291 | 17:56 Knoxville Mc Ghee Tyson | 12:35+2 дня Panama City Tocumen | 42h 39m layover 13h 23m - Orlando 22h 57m - San Jose | Allegiant Air | G43038 NK1309 AV643 |
| from $310 | 17:15 Knoxville Mc Ghee Tyson | 14:40+1 день Panama City Tocumen | 21h 25m layover 2h 54m - Miami 11h 30m - Medellin | Allegiant Air | G43477 NK973 AV322 |
| from $319 | 17:15 Knoxville Mc Ghee Tyson | 16:30+1 день Panama City Tocumen | 23h 15m layover 11h 9m - Miami 4h 12m - Bogota | Allegiant Air | G43477 NK862 AV60 |
| from $326 | 11:00 Knoxville Mc Ghee Tyson | 14:40+1 день Panama City Tocumen | 27h 40m layover 9h 9m - Miami 11h 30m - Medellin | Allegiant Air | G41415 NK973 AV322 |
| from $333 | 17:15 Knoxville Mc Ghee Tyson | 12:59+1 день Panama City Tocumen | 19h 44m layover 2h 54m - Miami 9h 35m - Medellin | Allegiant Air | G43477 NK973 CM856 |
| from $336 | 21:59 Knoxville Mc Ghee Tyson | 19:15+1 день Panama City Tocumen | 21h 16m layover 10h 22m - Orlando 4h 7m - Medellin | Allegiant Air | G41417 NK1473 AV316 |
| from $338 | 17:31 Knoxville Mc Ghee Tyson | 12:35+2 дня Panama City Tocumen | 43h 4m layover 16h 17m - Orlando 20h 35m - San Jose | Allegiant Air | G41411 NK1309 AV643 |
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on December 21, 2024
Flight Schedule Knoxville (Tennessee) to Panama City
Full flight schedule will help you in detecting at what time planes fly from Knoxville to Panama City. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
| Departure | Arrival | Flight Details | Flight Duration | Price |
|---|---|---|---|---|
|
10:00 — 05:11
+1 day
|
10:00 — 11:29
G41398
Allegiant Air
Knoxville — Denver
9h 47m stop
21:16 — 05:11
CM477
Compania Panamena de Aviacion
Denver — Panama City
|
19h 11m including layover |
Find flight
from$879 |
|
|
15:04 — 18:00
+1 day
|
15:04 — 16:55
G41430
Allegiant Air
Knoxville — Tampa
21h 37m stop
14:32 — 18:00
CM394
Compania Panamena de Aviacion
Tampa — Panama City
|
26h 56m including layover |
Find flight
from$551 |
|
|
20:49 — 18:00
+1 day
|
20:49 — 22:40
G43645
Allegiant Air
Knoxville — Tampa
15h 52m stop
14:32 — 18:00
CM394
Compania Panamena de Aviacion
Tampa — Panama City
|
21h 11m including layover |
Find flight
from$546 |
|
|
07:30 — 10:25
+1 day
|
07:30 — 09:14
G41417
Allegiant Air
Knoxville — Orlando
5h 21m stop
14:35 — 16:40
AV423
Avianca
Orlando — San Salvador
14h 50m stop
07:30 — 10:25
AV323
Avianca
San Salvador — Panama City
|
26h 55m including layover |
Find flight
from$394 |
|
|
07:30 — 00:20
+1 day
|
07:30 — 09:08
G41417
Allegiant Air
Knoxville — Orlando
5h 26m stop
14:40 — 18:35
AV219
Avianca
Orlando — Bogota
3h 55m stop
23:10 — 01:00
AV40
Avianca
Bogota — Panama City
|
16h 50m including layover |
Find flight
from$520 |
|
|
08:15 — 14:45
+1 day
|
08:15 — 10:05
G41396
Allegiant Air
Knoxville — New York
19h 40m stop
05:45 — 09:50
AV569
Avianca
New York — San Salvador
2h stop
11:50 — 14:45
AV317
Avianca
San Salvador — Panama City
|
30h 30m including layover |
Find flight
from$251 |
|
|
08:15 — 10:25
+1 day
|
08:15 — 10:05
G41396
Allegiant Air
Knoxville — New York
16h 30m stop
02:35 — 06:30
AV571
Avianca
New York — San Salvador
1h stop
07:30 — 10:25
AV323
Avianca
San Salvador — Panama City
|
26h 10m including layover |
Find flight
from$258 |
|
|
10:00 — 05:58
+1 day
|
10:00 — 11:29
G41398
Allegiant Air
Knoxville — Denver
3h 44m stop
15:13 — 20:05
AM659
Aeromexico
Denver — Mexico City
5h 15m stop
01:20 — 05:58
CM149
Compania Panamena de Aviacion
Mexico City — Panama City
|
19h 58m including layover |
Find flight
from$1107 |
|
|
11:00 — 10:25
+1 day
|
11:00 — 13:17
G41415
Allegiant Air
Knoxville — Miami
9h 48m stop
23:05 — 00:52
NK1031
Spirit Airlines
Miami — San Salvador
6h 38m stop
07:30 — 10:25
AV323
Avianca
San Salvador — Panama City
|
23h 25m including layover |
Find flight
from$269 |
|
|
11:00 — 14:45
+1 day
|
11:00 — 13:17
G41415
Allegiant Air
Knoxville — Miami
9h 48m stop
23:05 — 00:52
NK1031
Spirit Airlines
Miami — San Salvador
10h 58m stop
11:50 — 14:45
AV317
Avianca
San Salvador — Panama City
|
27h 45m including layover |
Find flight
from$269 |
|
|
12:25 — 20:19
+1 day
|
12:25 — 14:08
G43049
Allegiant Air
Knoxville — Tampa
20h 52m stop
11:00 — 12:15
3M59
Gulfstream International Airlines
Tampa — Miami
4h 47m stop
17:02 — 20:19
CM266
Compania Panamena de Aviacion
Miami — Panama City
|
31h 54m including layover |
Find flight
from$348 |
|
|
13:41 — 19:15
+1 day
|
13:41 — 15:58
G41416
Allegiant Air
Knoxville — Miami
18h 47m stop
10:45 — 14:17
NK237
Spirit Airlines
Miami — Medellin
3h 43m stop
18:00 — 19:15
AV316
Avianca
Medellin — Panama City
|
29h 34m including layover |
Find flight
from$359 |
|
|
13:50 — 12:35
+2 days
|
13:50 — 15:39
G43053
Allegiant Air
Knoxville — Orlando
19h 46m stop
11:25 — 13:40
NK1309
Spirit Airlines
Orlando — San Jose
20h 35m stop
10:15 — 12:35
AV643
Avianca
San Jose — Panama City
|
46h 45m including layover |
Find flight
from$346 |
|
|
17:15 — 12:35
+1 day
|
17:15 — 19:32
G43477
Allegiant Air
Knoxville — Miami
3h 33m stop
23:05 — 00:59
NK1755
Spirit Airlines
Miami — San Jose
9h 16m stop
10:15 — 12:35
AV643
Avianca
San Jose — Panama City
|
19h 20m including layover |
Find flight
from$272 |
|
|
17:15 — 21:00
+1 day
|
17:15 — 19:32
G43477
Allegiant Air
Knoxville — Miami
18h 38m stop
14:10 — 17:54
AV37
Avianca
Miami — Bogota
1h 21m stop
19:15 — 21:00
AV56
Avianca
Bogota — Panama City
|
27h 45m including layover |
Find flight
from$277 |
|
|
21:59 — 21:00
+1 day
|
21:59 — 23:43
G41417
Allegiant Air
Knoxville — Orlando
8h 57m stop
08:40 — 12:45
NK1921
Spirit Airlines
Orlando — Bogota
6h 30m stop
19:15 — 21:00
AV56
Avianca
Bogota — Panama City
|
23h 1m including layover |
Find flight
from$284 |
|
|
21:59 — 00:20
+2 days
|
21:59 — 23:43
G41417
Allegiant Air
Knoxville — Orlando
8h 57m stop
08:40 — 12:45
NK1921
Spirit Airlines
Orlando — Bogota
9h 45m stop
22:30 — 00:20
AV40
Avianca
Bogota — Panama City
|
26h 21m including layover |
Find flight
from$284 |
|
*Departure and arrival times - local. Updated on December 21, 2024
Flight Information
Below we will explain in detail what the flights cost on the destination from Knoxville to Panama City depends on and how to choose the most interesting flight option for you.
Distance between Knoxville and Panama City is 3010 miles. Time difference between the cities is 0h. Airplanes depart 07:30 to 21:59 from 1 Knoxville airport and arrive 07:30 to 21:59 to 2 Panama City airports. Average flight time is 24h 17m.
- The fastest flight 13h 19m
- Average flight time 24h 17m
- The earliest flight 07:30
- The latest flight 21:59
- Distance 1871 ml
The cheapest months to travel to Panama City are february (from 251 $), january (from 269 $), november (from 462 $).
The most expensive months are december (from 492 $), november (from 462 $), january (from 269 $).
What is the lowest airfare Knoxville to Panama City?
The cheapest plane ticket found by our users is $251. This airfare is for economy class on one-way G41396 flight by Allegiant Air for February 21, 2025 which leaves Mc Ghee Tyson in Knoxville at 08:15 am and arrives at Panama City Tocumen at 14:45.
Economy class
$251
Business class
?
First class
?
Popular Airlines on the Route
The flight Knoxville — Panama City is served by 1 regular airline and 1 low-cost airline. Most of the flights on this route are operated by Allegiant Air - 58 departures per week at the price of from $ 251 . And the most expensive tickets are offered by Allegiant Air airline - from $ 1107.
Direct flights
There’re no direct flights on this route. Try flights with stops.
Connecting Flights
There are 58 flights with layovers on the route. The fastest connecting flight is G43477 by Allegiant Air takes 13h 19m and the cheapest is G41396 by Allegiant Air for $251.
- G4 - Allegiant Airfrom $251Find
See more connecting flights
Airports
You can fly from Knoxville to Panama City from 1 airports (Mc Ghee Tyson).
Knoxville airports
- Mc Ghee Tyson-TYSfrom $251Find
Panama City airports
- Tocumen-PTYFind
- Paitilla-PACFind
Airplanes
There are flights to Panama City from Knoxville by 1 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Knoxville
You may also consider searching for discounted plane tickets to some other popular places from Knoxville within United States.
- from $80Find
- from $54Find
- from $56Find
- from $73Find
- from $76Find
- from $69Find
- from $78Find
- from $74Find
- from $64Find
- from $73Find
Top International Destinations from Knoxville
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
- from $69Find
- from $61Find
- from $64Find
How to book a plane ticket yourself?
- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
- Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
- Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
- Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
- That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
To find a plane ticket, please select dates.