Cheap Flights from Chicago, IL to Knoxville, TN from $47

Return flight: Knoxville – Chicago
Page navigation
Price Calendar Cheap Flights Flights Schedule

On Cheapflightsplus.com you will find 16 direct and 612 connecting flights from Chicago to Knoxville. You can compare airfare deals from 6 airlines and multiple travel sites from $47, book and save on cheap plane tickets and last minute offers. Also check out CHI-TYS flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Chicago to Knoxville Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $47 (one-way), $81 (round-trip).
Direct flights
  • Check to choose departure date Check to choose departure date
Check prices for return flight
Find flights

Best Flights from Chicago to Knoxville Today

Take a look at the list of non stop flights and flights with layovers from Chicago to Knoxville with the lowest price of $47. The fastest direct flight takes 1h 25m and the fastest connecting – 4h 41m.
Price Departure Arrival Flight Duration Airline Flight
from $47
Find flight
14:46
Chicago
Midway
 17:12
Knoxville
Mc Ghee Tyson
 1h 26m Allegiant Air
G41430
from $56
Find flight
14:54
Chicago
Midway
 17:20
Knoxville
Mc Ghee Tyson
 1h 26m Allegiant Air
G43046
from $239
Find flight
10:35
Chicago
O'Hare International
 13:25
Knoxville
Mc Ghee Tyson
 1h 50m United Airlines
UA4194
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 15, 2025
Full flight schedule will help you in detecting at what time planes fly from Chicago to Knoxville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
06:00 — 16:29
06:00 — 08:02 F91483 Frontier Airlines
Chicago — Denver
3h 50m stop
11:41 — 16:35 F92374 Frontier Airlines
Denver — Knoxville
9h 29m
including layover
Find flight
from$106
07:15 — 20:41
07:15 — 11:03 NK3200 Spirit Airlines
Chicago — Sanford
8h 3m stop
19:06 — 20:41 G42839 Allegiant Air
Sanford — Knoxville
12h 26m
including layover
Find flight
from$98
07:25 — 10:17
07:25 — 10:17 UA5726 United Airlines
Chicago — Knoxville
1h 52m
Find flight
from$240
10:35 — 13:25
10:35 — 13:25 UA4194 United Airlines
Chicago — Knoxville
1h 50m
Find flight
from$239
10:35 — 13:21
10:35 — 13:21 UA5836 United Airlines
Chicago — Knoxville
1h 46m
Find flight
from$240
14:10 — 17:00
14:10 — 17:00 UA5399 United Airlines
Chicago — Knoxville
1h 50m
Find flight
from$239
14:44 — 16:29
+1 day
14:44 — 16:33 F92209 Frontier Airlines
Chicago — Denver
19h 8m stop
11:41 — 16:35 F92374 Frontier Airlines
Denver — Knoxville
24h 45m
including layover
Find flight
from$103
14:46 — 17:12
14:46 — 17:12 G41430 Allegiant Air
Chicago — Knoxville
1h 26m
Find flight
from$47
14:53 — 17:18
14:53 — 17:18 G43025 Allegiant Air
Chicago — Knoxville
1h 25m
Find flight
from$49
14:54 — 17:22
14:54 — 17:22 G43036 Allegiant Air
Chicago — Knoxville
1h 28m
Find flight
from$51
14:54 — 17:20
14:54 — 17:20 G43046 Allegiant Air
Chicago — Knoxville
1h 26m
Find flight
from$56
15:46 — 18:38
15:46 — 18:38 UA454 United Airlines
Chicago — Knoxville
1h 52m
Find flight
from$240
18:17 — 16:11
+1 day
18:17 — 19:57 SY262 Sun Country Airlines
Chicago — Minneapolis
17h 11m stop
13:08 — 16:11 G41416 Allegiant Air
Minneapolis — Knoxville
20h 54m
including layover
Find flight
from$108
19:00 — 21:28
19:00 — 21:28 G41433 Allegiant Air
Chicago — Knoxville
1h 28m
Find flight
from$47
21:08 — 12:50
+1 day
21:08 — 00:29 NK2542 Spirit Airlines
Chicago — Newark
10h 26m stop
10:55 — 12:50 G43024 Allegiant Air
Newark — Knoxville
14h 42m
including layover
Find flight
from$105
*Departure and arrival times - local. Updated on September 15, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Chicago to Knoxville depends on and how to choose the most interesting flight option for you.

Distance between Chicago and Knoxville is 745 miles. Time difference between the cities is 1h. Airplanes depart 05:00 to 22:15 from 7 Chicago airports and arrive 05:00 to 22:15 to 1 Knoxville airport. Average flight time is 1h 48m.

  • The fastest flight 1h 25m
  • Average flight time 1h 48m
  • The earliest flight 05:00
  • The latest flight 22:15
  • Distance 463 ml

The cheapest months to travel to Knoxville are may (from 47 $), august (from 47 $), june (from 49 $).

The most expensive months are december (from 311 $), september (from 256 $), october (from 98 $).

What is the lowest airfare Chicago to Knoxville?

The cheapest plane ticket found by our users is $47. This airfare is for economy class on one-way G41430 flight by Allegiant Air for August 8, 2025 which leaves Midway in Chicago at 14:46 am and arrives at Knoxville Mc Ghee Tyson at 17:12.

Economy class
$47
Find
Business class
?
Find
First class
?
Find

Popular Airlines on the Route

The flight Chicago — Knoxville is served by 6 regular airlines and 4 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 3 departures per week at the price of from $ 103 . And the most expensive tickets are offered by United Airlines airline - from $ 688.

Direct flights

There are 16 nonstop flights on the route. The fastest direct flight is G43025 by Allegiant Air takes 1h 25m and the cheapest is G41430 by Allegiant Air for $47.

  • UA - United Airlines
    from $239
    Find
  • G4 - Allegiant Air
    from $47
    Find
See more direct flights

Connecting Flights

There are 612 flights with layovers on the route. The fastest connecting flight is UA2029 by United Airlines takes 4h 41m and the cheapest is G41430 by Allegiant Air for $98.

  • F9 - Frontier Airlines
    from $103
    Find
  • SY - Sun Country Airlines
    from $108
    Find
  • UA - United Airlines
    from $234
    Find
  • KG - Aerogaviota
    from $296
    Find
  • NK - Spirit Airlines
    from $98
    Find
  • G4 - Allegiant Air
    from $113
    Find
See more connecting flights

Airports

You can fly from Chicago to Knoxville from 7 airports (O'Hare International, Midway, Dupage County, Chicago FSS, Merrill C Meigs (closed), Pal-Waukee, Chicago NAS).

Chicago airports

  • O'Hare International-ORD
    from $98
    Find
  • Midway-MDW
    from $47
    Find
  • Dupage County-DPA
    Find
  • Chicago FSS-CHI
    Find
  • Merrill C Meigs (closed)-CGX
    Find
  • Pal-Waukee-PWK
    Find
  • Chicago NAS-NOH
    Find

Knoxville airports

  • Mc Ghee Tyson-TYS
    Find

Airplanes

There are flights to Knoxville from Chicago by 6 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Chicago

You may also consider searching for discounted plane tickets to some other popular places from Chicago within United States.

Top International Destinations from Chicago

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back