Cheap Flights from New Orleans, LA to Knoxville, TN from $100

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On Cheapflightsplus.com you will find 311 connecting flights from New Orleans to Knoxville. You can compare airfare deals from 4 airlines and multiple travel sites from $100, book and save on cheap plane tickets and last minute offers. Also check out MSY-TYS flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip New Orleans to Knoxville Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $100 (one-way), $171 (round-trip).

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Best Flights from New Orleans to Knoxville Today

Take a look at the list of non stop flights and flights with layovers from New Orleans to Knoxville with the lowest price of $100. Take a look at the list of flights with layovers from New Orleans to Knoxville from $100. There’re no direct flights. The fastest connecting flight – 4h 18m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $100 Find flight	20:10 New Orleans Louis Armstrong Intl	10:11+1 день Knoxville Mc Ghee Tyson	13h 1m layover 9h 26m - Orlando	Spirit Airlines	NK1068 G43064
from $106 Find flight	17:55 New Orleans Louis Armstrong Intl	16:12+1 день Knoxville Mc Ghee Tyson	21h 17m layover 16h 31m - Minneapolis	Sun Country Airlines	SY1804 G43063
from $134 Find flight	05:10 New Orleans Louis Armstrong Intl	16:47 Knoxville Mc Ghee Tyson	10h 37m layover 0h 52m - Charlotte 4h 45m - Washington D.C.	Spirit Airlines	NK2427 NK2672 G41398
from $154 Find flight	17:55 New Orleans Louis Armstrong Intl	22:15+1 день Knoxville Mc Ghee Tyson	27h 20m layover 11h 10m - Minneapolis 9h 17m - Jacksonville	Sun Country Airlines	SY1804 SY325 G41440

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 15, 2025

Flight Schedule New Orleans (Louisiana) to Knoxville (Tennessee)

Full flight schedule will help you in detecting at what time planes fly from New Orleans to Knoxville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
06:20 — 08:02 +1 day	06:20 — 09:14 NK1420 Spirit Airlines New Orleans — Miami 20h 46m stop 06:00 — 08:02 G4520 Allegiant Air Miami — Knoxville	24h 42m including layover	Find flight from$117
07:53 — 10:04 +1 day	07:53 — 10:51 NK1053 Spirit Airlines New Orleans — Miami 21h 9m stop 08:00 — 10:04 G4527 Allegiant Air Miami — Knoxville	25h 11m including layover	Find flight from$113
07:53 — 11:18 +1 day	07:53 — 10:51 NK1053 Spirit Airlines New Orleans — Miami 22h 24m stop 09:15 — 11:18 G4531 Allegiant Air Miami — Knoxville	26h 25m including layover	Find flight from$116
13:31 — 08:17 +1 day	13:31 — 16:27 NK2211 Spirit Airlines New Orleans — Miami 13h 48m stop 06:15 — 08:17 G4508 Allegiant Air Miami — Knoxville	17h 46m including layover	Find flight from$112
13:40 — 13:27 +1 day	13:40 — 16:33 NK1442 Spirit Airlines New Orleans — Sanford 19h 17m stop 11:50 — 13:27 G41400 Allegiant Air Sanford — Knoxville	22h 47m including layover	Find flight from$110
13:44 — 10:04 +1 day	13:44 — 16:41 NK1055 Spirit Airlines New Orleans — Miami 15h 19m stop 08:00 — 10:04 G4527 Allegiant Air Miami — Knoxville	19h 20m including layover	Find flight from$113
13:44 — 11:18 +1 day	13:44 — 16:41 NK1055 Spirit Airlines New Orleans — Miami 16h 34m stop 09:15 — 11:18 G4531 Allegiant Air Miami — Knoxville	20h 34m including layover	Find flight from$116
17:20 — 10:04 +1 day	17:20 — 20:21 NK641 Spirit Airlines New Orleans — Miami 11h 39m stop 08:00 — 10:04 G4527 Allegiant Air Miami — Knoxville	15h 44m including layover	Find flight from$113
17:55 — 16:12 +1 day	17:36 — 20:19 SY1804 Sun Country Airlines New Orleans — Minneapolis 16h 31m stop 13:09 — 16:12 G43063 Allegiant Air Minneapolis — Knoxville	21h 17m including layover	Find flight from$106
18:19 — 22:10 +1 day	18:19 — 19:44 NK2066 Spirit Airlines New Orleans — Houston 23h 19m stop 19:03 — 22:10 G41427 Allegiant Air Houston — Knoxville	26h 51m including layover	Find flight from$128
20:10 — 10:11 +1 day	20:10 — 23:01 NK1068 Spirit Airlines New Orleans — Orlando 9h 26m stop 08:27 — 10:11 G43064 Allegiant Air Orlando — Knoxville	13h 1m including layover	Find flight from$100
20:10 — 21:20 +1 day	20:10 — 23:01 NK1068 Spirit Airlines New Orleans — Sanford 20h 44m stop 19:45 — 21:20 G42885 Allegiant Air Sanford — Knoxville	24h 10m including layover	Find flight from$105
21:04 — 13:27 +1 day	21:04 — 23:59 NK433 Spirit Airlines New Orleans — Sanford 11h 51m stop 11:50 — 13:27 G41400 Allegiant Air Sanford — Knoxville	15h 23m including layover	Find flight from$110
21:10 — 21:20 +1 day	21:10 — 00:02 NK2558 Spirit Airlines New Orleans — Sanford 19h 43m stop 19:45 — 21:20 G42885 Allegiant Air Sanford — Knoxville	23h 10m including layover	Find flight from$105
21:10 — 10:11 +1 day	21:10 — 00:02 NK2558 Spirit Airlines New Orleans — Orlando 8h 25m stop 08:27 — 10:11 G43064 Allegiant Air Orlando — Knoxville	12h 1m including layover	Find flight from$110

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on September 15, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from New Orleans to Knoxville depends on and how to choose the most interesting flight option for you.

Distance between New Orleans and Knoxville is 872 miles. Time difference between the cities is 1h. Airplanes depart 05:00 to 21:50 from 3 New Orleans airports and arrive 05:00 to 21:50 to 1 Knoxville airport. Average flight time is 20h 34m.

The fastest flight 4h 18m
Average flight time 20h 34m
The earliest flight 05:00
The latest flight 21:50
Distance 542 ml

The cheapest months to travel to Knoxville are july (from 100 $), august (from 106 $), september (from 116 $).

The most expensive months are december (from 380 $), january (from 314 $), october (from 130 $).

What is the lowest airfare New Orleans to Knoxville?

The cheapest plane ticket found by our users is $100. This airfare is for economy class on one-way NK1068 flight by Spirit Airlines for July 13, 2025 which leaves Louis Armstrong Intl in New Orleans at 20:10 am and arrives at Knoxville Mc Ghee Tyson at 10:11.

Economy class

$100

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First class

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Popular Airlines on the Route

The flight New Orleans — Knoxville is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Sun Country Airlines - 8 departures per week at the price of from $ 106 . And the most expensive tickets are offered by United Airlines airline - from $ 535.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 311 flights with layovers on the route. The fastest connecting flight is UA2296 by United Airlines takes 4h 18m and the cheapest is NK1068 by Spirit Airlines for $100.

SY - Sun Country Airlines

from $106

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MX - Mexicana

from $162

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UA - United Airlines

from $256

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NK - Spirit Airlines

from $100

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Airports

You can fly from New Orleans to Knoxville from 3 airports (Lakefront, Louis Armstrong Intl, Alvin Callendar).

New Orleans airports

Lakefront-NEW

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Louis Armstrong Intl-MSY

from $100
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Alvin Callendar-NBG

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Knoxville airports

Mc Ghee Tyson-TYS

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Airplanes

There are flights to Knoxville from New Orleans by 4 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from New Orleans

You may also consider searching for discounted plane tickets to some other popular places from New Orleans within United States.

New Orleans — Orlando

from $56

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New Orleans — Houston

from $76

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New Orleans — Miami

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New Orleans — Atlanta

from $130

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New Orleans — Chicago

from $63

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New Orleans — Dallas

from $76

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New Orleans — Denver

from $57

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New Orleans — Boston

from $77

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New Orleans — Nashville

from $74

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New Orleans — Austin

from $67

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Top International Destinations from New Orleans

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

New Orleans — London

from $79

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New Orleans — Cancun

from $77

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New Orleans — Paris

from $73

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New Orleans — Toronto

from $79

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New Orleans — Punta Cana

from $57

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New Orleans — Vancouver

from $73

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New Orleans — San Juan

from $73

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New Orleans — Mexico City

from $56

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New Orleans — Belize

from $62

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New Orleans — Montreal

from $70

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How to book a plane ticket yourself?

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That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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