Cheap Flights from New Orleans, LA to Knoxville, TN from $102

On Cheapflightsplus.com you will find 311 connecting flights from New Orleans to Knoxville. You can compare airfare deals from 4 airlines and multiple travel sites from $102, book and save on cheap plane tickets and last minute offers. Also check out MSY-TYS flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from New Orleans to Knoxville depends on and how to choose the most interesting flight option for you.

Distance between New Orleans and Knoxville is 872 miles. Time difference between the cities is 1h. Airplanes depart 05:00 to 21:50 from 3 New Orleans airports and arrive 05:00 to 21:50 to 1 Knoxville airport. Average flight time is 20h 34m.

  • The fastest flight 4h 18m
  • Average flight time 20h 34m
  • The earliest flight 05:00
  • The latest flight 21:50
  • Distance 542 ml

The cheapest months to travel to Knoxville are july (from 102 $), august (from 108 $), september (from 118 $).

The most expensive months are december (from 388 $), january (from 321 $), october (from 133 $).

What is the lowest airfare New Orleans to Knoxville?

The cheapest plane ticket found by our users is $102. This airfare is for economy class on one-way NK1068 flight by Spirit Airlines for July 13, 2025 which leaves Louis Armstrong Intl in New Orleans at 20:10 am and arrives at Knoxville Mc Ghee Tyson at 10:11.

Economy class
$102
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Business class
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First class
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Flight Schedule New Orleans (Louisiana) to Knoxville (Tennessee)

06:20 — 08:02+1day
24h 42m flight time
Find flight
from$120
06:20 — 09:14 New Orleans — Miami
NK1420 Spirit Airlines
20h 46m stop
06:00 — 08:02 Miami — Knoxville
G4520 Allegiant Air
07:53 — 10:04+1day
25h 11m flight time
Find flight
from$115
07:53 — 10:51 New Orleans — Miami
NK1053 Spirit Airlines
21h 9m stop
08:00 — 10:04 Miami — Knoxville
G4527 Allegiant Air
07:53 — 11:18+1day
26h 25m flight time
Find flight
from$118
07:53 — 10:51 New Orleans — Miami
NK1053 Spirit Airlines
22h 24m stop
09:15 — 11:18 Miami — Knoxville
G4531 Allegiant Air
13:31 — 08:17+1day
17h 46m flight time
Find flight
from$115
13:31 — 16:27 New Orleans — Miami
NK2211 Spirit Airlines
13h 48m stop
06:15 — 08:17 Miami — Knoxville
G4508 Allegiant Air
13:40 — 13:27+1day
22h 47m flight time
Find flight
from$113
13:40 — 16:33 New Orleans — Sanford
NK1442 Spirit Airlines
19h 17m stop
11:50 — 13:27 Sanford — Knoxville
G41400 Allegiant Air
13:44 — 10:04+1day
19h 20m flight time
Find flight
from$115
13:44 — 16:41 New Orleans — Miami
NK1055 Spirit Airlines
15h 19m stop
08:00 — 10:04 Miami — Knoxville
G4527 Allegiant Air
13:44 — 11:18+1day
20h 34m flight time
Find flight
from$118
13:44 — 16:41 New Orleans — Miami
NK1055 Spirit Airlines
16h 34m stop
09:15 — 11:18 Miami — Knoxville
G4531 Allegiant Air
17:20 — 10:04+1day
15h 44m flight time
Find flight
from$115
17:20 — 20:21 New Orleans — Miami
NK641 Spirit Airlines
11h 39m stop
08:00 — 10:04 Miami — Knoxville
G4527 Allegiant Air
17:55 — 16:12+1day
21h 17m flight time
Find flight
from$108
17:36 — 20:19 New Orleans — Minneapolis
SY1804 Sun Country Airlines
16h 31m stop
13:09 — 16:12 Minneapolis — Knoxville
G43063 Allegiant Air
20:10 — 10:11+1day
13h 1m flight time
Find flight
from$102
20:10 — 23:01 New Orleans — Orlando
NK1068 Spirit Airlines
9h 26m stop
08:27 — 10:11 Orlando — Knoxville
G43064 Allegiant Air
20:10 — 21:20+1day
24h 10m flight time
Find flight
from$107
20:10 — 23:01 New Orleans — Sanford
NK1068 Spirit Airlines
20h 44m stop
19:45 — 21:20 Sanford — Knoxville
G42885 Allegiant Air
21:04 — 13:27+1day
15h 23m flight time
Find flight
from$113
21:04 — 23:59 New Orleans — Sanford
NK433 Spirit Airlines
11h 51m stop
11:50 — 13:27 Sanford — Knoxville
G41400 Allegiant Air
21:04 — 16:41+1day
18h 37m flight time
Find flight
from$123
21:04 — 23:59 New Orleans — Sanford
NK433 Spirit Airlines
15h 7m stop
16:48 — 18:25 Sanford — Knoxville
G43035 Allegiant Air
21:10 — 21:20+1day
23h 10m flight time
Find flight
from$107
21:10 — 00:02 New Orleans — Sanford
NK2558 Spirit Airlines
19h 43m stop
19:45 — 21:20 Sanford — Knoxville
G42885 Allegiant Air
21:10 — 10:11+1day
12h 1m flight time
Find flight
from$113
21:10 — 00:02 New Orleans — Orlando
NK2558 Spirit Airlines
8h 25m stop
08:27 — 10:11 Orlando — Knoxville
G43064 Allegiant Air
Full flight schedule will help you in detecting at what time planes fly from New Orleans to Knoxville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on October 16, 2025.

Popular Airlines on the Route

The flight New Orleans — Knoxville is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Sun Country Airlines - 8 departures per week at the price of from $ 108 . And the most expensive tickets are offered by United Airlines airline - from $ 547.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 311 flights with layovers on the route. The fastest connecting flight is UA2296 by United Airlines takes 4h 18m and the cheapest is NK1068 by Spirit Airlines for $102.

  • SY - Sun Country Airlines
    from $108
    Find
  • MX - Mexicana
    from $165
    Find
  • UA - United Airlines
    from $262
    Find
  • NK - Spirit Airlines
    from $102
    Find
See more connecting flights

Airports

You can fly from New Orleans to Knoxville from 3 airports (Lakefront, Louis Armstrong Intl, Alvin Callendar).

New Orleans airports

  • Lakefront-NEW
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  • Louis Armstrong Intl-MSY
    from $102
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  • Alvin Callendar-NBG
    Find

Knoxville airports

  • Mc Ghee Tyson-TYS
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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