Cheap Flights from New Orleans, LA to Knoxville, TN from $81

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On Cheapflightsplus.com you will find 311 connecting flights from New Orleans to Knoxville. You can compare airfare deals from 4 airlines and multiple travel sites from $81, book and save on cheap plane tickets and last minute offers. Also check out MSY-TYS flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip New Orleans to Knoxville Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $81 (one-way), $139 (round-trip).

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Best Flights from New Orleans to Knoxville Today

Take a look at the list of non stop flights and flights with layovers from New Orleans to Knoxville with the lowest price of $81. Take a look at the list of flights with layovers from New Orleans to Knoxville from $81. There’re no direct flights. The fastest connecting flight – 4h 18m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $81 Find flight	20:10 New Orleans Louis Armstrong Intl	10:11+1 день Knoxville Mc Ghee Tyson	13h 1m layover 9h 26m - Orlando	Spirit Airlines	NK1068 G43064
from $84 Find flight	21:10 New Orleans Louis Armstrong Intl	21:20+1 день Knoxville Mc Ghee Tyson	23h 10m layover 19h 43m - Sanford	Spirit Airlines	NK2558 G42885
from $85 Find flight	17:55 New Orleans Louis Armstrong Intl	16:12+1 день Knoxville Mc Ghee Tyson	21h 17m layover 16h 31m - Minneapolis	Sun Country Airlines	SY1804 G43063
from $89 Find flight	21:10 New Orleans Louis Armstrong Intl	10:11+1 день Knoxville Mc Ghee Tyson	12h 1m layover 8h 25m - Orlando	Spirit Airlines	NK2558 G43064
from $89 Find flight	21:04 New Orleans Louis Armstrong Intl	13:27+1 день Knoxville Mc Ghee Tyson	15h 23m layover 11h 51m - Sanford	Spirit Airlines	NK433 G41400
from $89 Find flight	13:40 New Orleans Louis Armstrong Intl	13:27+1 день Knoxville Mc Ghee Tyson	22h 47m layover 19h 17m - Sanford	Spirit Airlines	NK1442 G41400
from $90 Find flight	17:20 New Orleans Louis Armstrong Intl	10:04+1 день Knoxville Mc Ghee Tyson	15h 44m layover 11h 39m - Miami	Spirit Airlines	NK641 G4527
from $90 Find flight	13:31 New Orleans Louis Armstrong Intl	08:17+1 день Knoxville Mc Ghee Tyson	17h 46m layover 13h 48m - Miami	Spirit Airlines	NK2211 G4508
from $90 Find flight	13:44 New Orleans Louis Armstrong Intl	10:04+1 день Knoxville Mc Ghee Tyson	19h 20m layover 15h 19m - Miami	Spirit Airlines	NK1055 G4527
from $90 Find flight	07:53 New Orleans Louis Armstrong Intl	10:04+1 день Knoxville Mc Ghee Tyson	25h 11m layover 21h 9m - Miami	Spirit Airlines	NK1053 G4527
from $93 Find flight	13:44 New Orleans Louis Armstrong Intl	11:18+1 день Knoxville Mc Ghee Tyson	20h 34m layover 16h 34m - Miami	Spirit Airlines	NK1055 G4531
from $93 Find flight	07:53 New Orleans Louis Armstrong Intl	11:18+1 день Knoxville Mc Ghee Tyson	26h 25m layover 22h 24m - Miami	Spirit Airlines	NK1053 G4531
from $94 Find flight	06:20 New Orleans Louis Armstrong Intl	08:02+1 день Knoxville Mc Ghee Tyson	24h 42m layover 20h 46m - Miami	Spirit Airlines	NK1420 G4520
from $97 Find flight	21:04 New Orleans Louis Armstrong Intl	16:41+1 день Knoxville Mc Ghee Tyson	18h 37m layover 15h 7m - Sanford	Spirit Airlines	NK433 G43035
from $108 Find flight	05:10 New Orleans Louis Armstrong Intl	16:47 Knoxville Mc Ghee Tyson	10h 37m layover 0h 52m - Charlotte 4h 45m - Washington D.C.	Spirit Airlines	NK2427 NK2672 G41398
from $124 Find flight	17:55 New Orleans Louis Armstrong Intl	22:15+1 день Knoxville Mc Ghee Tyson	27h 20m layover 11h 10m - Minneapolis 9h 17m - Jacksonville	Sun Country Airlines	SY1804 SY325 G41440

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on June 25, 2025

Flight Schedule New Orleans (Louisiana) to Knoxville (Tennessee)

Full flight schedule will help you in detecting at what time planes fly from New Orleans to Knoxville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
05:00 — 21:20	05:00 — 07:46 NK2277 Spirit Airlines New Orleans — Sanford 11h 59m stop 19:45 — 21:20 G42962 Allegiant Air Sanford — Knoxville	15h 20m including layover	Find flight from$118
05:00 — 14:18	05:00 — 07:46 NK2277 Spirit Airlines New Orleans — Sanford 4h 57m stop 12:43 — 14:18 G42961 Allegiant Air Sanford — Knoxville	8h 18m including layover	Find flight from$123
06:20 — 08:02 +1 day	06:20 — 09:14 NK1420 Spirit Airlines New Orleans — Miami 20h 46m stop 06:00 — 08:02 G4520 Allegiant Air Miami — Knoxville	24h 42m including layover	Find flight from$94
06:20 — 14:21	06:20 — 09:14 NK1420 Spirit Airlines New Orleans — Miami 3h 5m stop 12:19 — 14:21 G42135 Allegiant Air Miami — Knoxville	7h 1m including layover	Find flight from$139
07:53 — 10:04 +1 day	07:53 — 10:51 NK1053 Spirit Airlines New Orleans — Miami 21h 9m stop 08:00 — 10:04 G4527 Allegiant Air Miami — Knoxville	25h 11m including layover	Find flight from$90
07:53 — 11:18 +1 day	07:53 — 10:51 NK1053 Spirit Airlines New Orleans — Miami 22h 24m stop 09:15 — 11:18 G4531 Allegiant Air Miami — Knoxville	26h 25m including layover	Find flight from$93
10:35 — 17:00	10:35 — 13:15 UA310 United Airlines New Orleans — Chicago 55m stop 14:10 — 17:00 UA5399 United Airlines Chicago — Knoxville	5h 25m including layover	Find flight from$206
11:56 — 17:37	12:03 — 13:20 UA2253 United Airlines New Orleans — Houston 1h 1m stop 14:45 — 18:11 UA4890 United Airlines Houston — Knoxville	4h 41m including layover	Find flight from$206
12:48 — 21:20	12:48 — 15:38 NK1573 Spirit Airlines New Orleans — Sanford 4h 7m stop 19:45 — 21:20 G42885 Allegiant Air Sanford — Knoxville	7h 32m including layover	Find flight from$118
12:48 — 10:11 +1 day	12:48 — 15:38 NK1573 Spirit Airlines New Orleans — Orlando 16h 49m stop 08:27 — 10:11 G43064 Allegiant Air Orlando — Knoxville	20h 23m including layover	Find flight from$165
13:31 — 08:17 +1 day	13:31 — 16:27 NK2211 Spirit Airlines New Orleans — Miami 13h 48m stop 06:15 — 08:17 G4508 Allegiant Air Miami — Knoxville	17h 46m including layover	Find flight from$90
13:40 — 13:27 +1 day	13:40 — 16:33 NK1442 Spirit Airlines New Orleans — Sanford 19h 17m stop 11:50 — 13:27 G41400 Allegiant Air Sanford — Knoxville	22h 47m including layover	Find flight from$89
14:16 — 19:34	14:16 — 15:40 UA2296 United Airlines New Orleans — Houston 40m stop 16:20 — 19:34 UA4900 United Airlines Houston — Knoxville	4h 18m including layover	Find flight from$206
15:11 — 16:00 +1 day	15:11 — 16:51 NK1410 Spirit Airlines New Orleans — Las Vegas 16h 14m stop 09:05 — 16:00 G462 Allegiant Air Las Vegas — Knoxville	23h 49m including layover	Find flight from$168
15:27 — 13:38 +1 day	15:27 — 17:25 NK1282 Spirit Airlines New Orleans — Las Vegas 13h 20m stop 06:45 — 13:38 G47 Allegiant Air Las Vegas — Knoxville	21h 11m including layover	Find flight from$189
17:20 — 10:04 +1 day	17:20 — 20:21 NK641 Spirit Airlines New Orleans — Miami 11h 39m stop 08:00 — 10:04 G4527 Allegiant Air Miami — Knoxville	15h 44m including layover	Find flight from$90
17:55 — 16:12 +1 day	17:36 — 20:19 SY1804 Sun Country Airlines New Orleans — Minneapolis 16h 31m stop 13:09 — 16:12 G43063 Allegiant Air Minneapolis — Knoxville	21h 17m including layover	Find flight from$85
18:19 — 22:10 +1 day	18:19 — 19:44 NK2066 Spirit Airlines New Orleans — Houston 23h 19m stop 19:03 — 22:10 G41427 Allegiant Air Houston — Knoxville	26h 51m including layover	Find flight from$102
20:10 — 10:11 +1 day	20:10 — 23:01 NK1068 Spirit Airlines New Orleans — Orlando 9h 26m stop 08:27 — 10:11 G43064 Allegiant Air Orlando — Knoxville	13h 1m including layover	Find flight from$81
20:10 — 21:20 +1 day	20:10 — 23:01 NK1068 Spirit Airlines New Orleans — Sanford 20h 44m stop 19:45 — 21:20 G42885 Allegiant Air Sanford — Knoxville	24h 10m including layover	Find flight from$84
21:04 — 13:27 +1 day	21:04 — 23:59 NK433 Spirit Airlines New Orleans — Sanford 11h 51m stop 11:50 — 13:27 G41400 Allegiant Air Sanford — Knoxville	15h 23m including layover	Find flight from$89
21:10 — 21:20 +1 day	21:10 — 00:02 NK2558 Spirit Airlines New Orleans — Sanford 19h 43m stop 19:45 — 21:20 G42885 Allegiant Air Sanford — Knoxville	23h 10m including layover	Find flight from$84

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on June 25, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from New Orleans to Knoxville depends on and how to choose the most interesting flight option for you.

Distance between New Orleans and Knoxville is 872 miles. Time difference between the cities is 1h. Airplanes depart 05:00 to 21:50 from 3 New Orleans airports and arrive 05:00 to 21:50 to 1 Knoxville airport. Average flight time is 20h 34m.

The fastest flight 4h 18m
Average flight time 20h 34m
The earliest flight 05:00
The latest flight 21:50
Distance 542 ml

The cheapest months to travel to Knoxville are july (from 108 $), august (from 114 $), september (from 124 $).

The most expensive months are june (from 408 $), december (from 408 $), january (from 338 $).

What is the lowest airfare New Orleans to Knoxville?

The cheapest plane ticket found by our users is $81. This airfare is for economy class on one-way NK1068 flight by Spirit Airlines for July 13, 2025 which leaves Louis Armstrong Intl in New Orleans at 20:10 am and arrives at Knoxville Mc Ghee Tyson at 10:11.

Economy class

$81

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First class

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Popular Airlines on the Route

The flight New Orleans — Knoxville is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Sun Country Airlines - 8 departures per week at the price of from $ 85 . And the most expensive tickets are offered by United Airlines airline - from $ 431.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 311 flights with layovers on the route. The fastest connecting flight is UA2296 by United Airlines takes 4h 18m and the cheapest is NK1068 by Spirit Airlines for $81.

SY - Sun Country Airlines

from $85

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MX - Mexicana

from $130

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UA - United Airlines

from $206

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NK - Spirit Airlines

from $81

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Airports

You can fly from New Orleans to Knoxville from 3 airports (Lakefront, Louis Armstrong Intl, Alvin Callendar).

New Orleans airports

Lakefront-NEW

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Louis Armstrong Intl-MSY

from $81
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Alvin Callendar-NBG

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Knoxville airports

Mc Ghee Tyson-TYS

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Airplanes

There are flights to Knoxville from New Orleans by 4 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from New Orleans

You may also consider searching for discounted plane tickets to some other popular places from New Orleans within United States.

New Orleans — Orlando

from $56

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New Orleans — Houston

from $76

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New Orleans — Miami

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New Orleans — Atlanta

from $130

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New Orleans — Chicago

from $63

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New Orleans — Dallas

from $76

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New Orleans — Denver

from $57

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New Orleans — Boston

from $77

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New Orleans — Nashville

from $74

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New Orleans — Austin

from $67

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Top International Destinations from New Orleans

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

New Orleans — London

from $79

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New Orleans — Cancun

from $77

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New Orleans — Paris

from $73

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New Orleans — Toronto

from $79

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New Orleans — Punta Cana

from $57

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New Orleans — Vancouver

from $73

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New Orleans — San Juan

from $73

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New Orleans — Mexico City

from $56

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New Orleans — Belize

from $62

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New Orleans — Montreal

from $70

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How to book a plane ticket yourself?

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