Cheap Flights from Des Moines, IA to Houston, TX from $159

Return flight: Houston – Des Moines

On Cheapflightsplus.com you will find 41 connecting flights from Des Moines to Houston. You can compare airfare deals from 3 airlines and multiple travel sites from $159, book and save on cheap plane tickets and last minute offers. Also check out DSM-HOU flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Des Moines to Houston Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $159 (one-way), $273 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Des Moines to Houston. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
05:45 — 11:15
05:45 — 06:58 UA4700 United Airlines
Des Moines — Denver
47m stop
07:45 — 11:15 UA1720 United Airlines
Denver — Houston
5h 30m
including layover
Find flight
from$529
05:45 — 13:11
05:45 — 06:58 UA4700 United Airlines
Des Moines — Denver
2h 42m stop
09:40 — 13:11 UA2676 United Airlines
Denver — Houston
7h 26m
including layover
Find flight
from$529
07:00 — 16:34
07:00 — 11:12 G4434 Allegiant Air
Des Moines — Miami
3h 39m stop
14:51 — 16:34 NK909 Spirit Airlines
Miami — Houston
9h 34m
including layover
Find flight
from$323
08:00 — 21:42
08:00 — 09:28 UA1363 United Airlines
Des Moines — Chicago
9h 7m stop
18:35 — 21:42 UA739 United Airlines
Chicago — Houston
13h 42m
including layover
Find flight
from$293
08:00 — 22:59
08:00 — 09:28 UA1363 United Airlines
Des Moines — Chicago
10h 27m stop
19:55 — 22:59 UA483 United Airlines
Chicago — Houston
14h 59m
including layover
Find flight
from$293
09:10 — 22:58
09:10 — 10:17 UA581 United Airlines
Des Moines — Denver
9h 13m stop
19:30 — 22:58 UA312 United Airlines
Denver — Houston
13h 48m
including layover
Find flight
from$369
09:10 — 23:58
09:10 — 10:17 UA581 United Airlines
Des Moines — Denver
10h 13m stop
20:30 — 23:58 UA2419 United Airlines
Denver — Houston
14h 48m
including layover
Find flight
from$369
11:29 — 17:03
11:29 — 12:57 UA1373 United Airlines
Des Moines — Chicago
1h 3m stop
14:00 — 17:03 UA1373 United Airlines
Chicago — Houston
5h 34m
including layover
Find flight
from$293
11:29 — 21:42
11:29 — 12:57 UA1373 United Airlines
Des Moines — Chicago
5h 38m stop
18:35 — 21:42 UA739 United Airlines
Chicago — Houston
10h 13m
including layover
Find flight
from$293
13:47 — 21:13
13:47 — 15:00 UA5835 United Airlines
Des Moines — Denver
2h 45m stop
17:45 — 21:13 UA1894 United Airlines
Denver — Houston
7h 26m
including layover
Find flight
from$319
13:47 — 22:58
13:47 — 15:00 UA5835 United Airlines
Des Moines — Denver
4h 30m stop
19:30 — 22:58 UA312 United Airlines
Denver — Houston
9h 11m
including layover
Find flight
from$338
15:44 — 00:21
+1 day
15:44 — 17:07 G42062 Allegiant Air
Des Moines — Las Vegas
2h 4m stop
19:11 — 00:21 NK2394 Spirit Airlines
Las Vegas — Houston
8h 37m
including layover
Find flight
from$223
15:44 — 01:25
+1 day
15:44 — 17:07 G42062 Allegiant Air
Des Moines — Las Vegas
3h 10m stop
20:17 — 01:25 NK3727 Spirit Airlines
Las Vegas — Houston
9h 41m
including layover
Find flight
from$223
17:13 — 08:31
+1 day
17:06 — 18:15 UA1781 United Airlines
Des Moines — Denver
10h 40m stop
05:00 — 08:27 UA320 United Airlines
Denver — Houston
15h 18m
including layover
Find flight
from$251
17:13 — 22:58
17:13 — 18:20 UA1781 United Airlines
Des Moines — Denver
1h 10m stop
19:30 — 22:58 UA312 United Airlines
Denver — Houston
5h 45m
including layover
Find flight
from$274
21:21 — 13:25
+1 day
18:52 — 19:58 F91677 Frontier Airlines
Des Moines — Denver
11h 29m stop
08:36 — 12:03 F93206 Frontier Airlines
Denver — Houston
16h 4m
including layover
Find flight
from$159
21:21 — 18:31
+1 day
21:21 — 22:20 F91677 Frontier Airlines
Des Moines — Denver
16h 40m stop
15:00 — 18:31 F91162 Frontier Airlines
Denver — Houston
21h 10m
including layover
Find flight
from$193
06:00 — 23:29
06:00 — 09:46 G4444 Allegiant Air
Des Moines — Orlando
4h 59m stop
14:45 — 16:52 NK506 Spirit Airlines
Orlando — Chicago
3h 50m stop
20:42 — 23:29 NK1150 Spirit Airlines
Chicago — Houston
17h 29m
including layover
Find flight
from$365
06:00 — 22:03
06:00 — 09:46 G4444 Allegiant Air
Des Moines — Orlando
5h 13m stop
14:59 — 16:38 NK1850 Spirit Airlines
Orlando — Atlanta
4h 15m stop
20:53 — 22:03 NK967 Spirit Airlines
Atlanta — Houston
16h 3m
including layover
Find flight
from$745
07:00 — 22:38
07:00 — 11:12 G4434 Allegiant Air
Des Moines — Miami
3h 53m stop
15:05 — 16:10 NK322 Spirit Airlines
Miami — Tampa
5h 2m stop
21:12 — 22:38 NK3127 Spirit Airlines
Tampa — Houston
15h 38m
including layover
Find flight
from$332
*Departure and arrival times - local. Updated on January 15, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Des Moines to Houston depends on and how to choose the most interesting flight option for you.

Distance between Des Moines and Houston is 1330 miles. Time difference between the cities is 0h. Airplanes depart 05:45 to 21:21 from 1 Des Moines airport and arrive 05:45 to 21:21 to 15 Houston airports. Average flight time is 13h 1m.

  • The fastest flight 5h 30m
  • Average flight time 13h 1m
  • The earliest flight 05:45
  • The latest flight 21:21
  • Distance 827 ml

The cheapest months to travel to Houston are november (from 53 $), february (from 159 $), december (from 269 $).

What is the lowest airfare Des Moines to Houston?

The cheapest plane ticket found by our users is $159. This airfare is for economy class on one-way F91677 flight by Frontier Airlines for February 21, 2025 which leaves Des Moines International Airport in Des Moines at 21:21 am and arrives at Houston George Bush at 13:25.

Economy class
$159
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Business class
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First class
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Popular Airlines on the Route

The flight Des Moines — Houston is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by United Airlines - 24 departures per week at the price of from $ 251 . And the most expensive tickets are offered by Allegiant Air airline - from $ 745.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 41 flights with layovers on the route. The fastest connecting flight is UA4700 by United Airlines takes 5h 30m and the cheapest is F91677 by Frontier Airlines for $159.

  • from $251
    Find
  • F9 - Frontier Airlines
    from $159
    Find
  • G4 - Allegiant Air
    from $223
    Find
See more connecting flights

Airports

You can fly from Des Moines to Houston from 1 airports (Des Moines International Airport).

Des Moines airports

  • Des Moines International Airport-DSM
    from $159
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Houston airports

  • Ellington Field-EFD
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  • West Houston-IWS
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  • Hobby-HOU
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  • Park Ten Heliport-JPT
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  • Andrau Airpark-AAP
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  • George Bush-IAH
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  • Greenway Plaza H/P-JGP
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  • David Wayne Hooks-DWH
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  • Transco Twr Galleria-JGQ
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  • Westchase Hilton H/P-JWH
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  • Spaceland-SPX
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  • Woodlawns-JWL
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  • Marriot Astrodome Heliport-JMA
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  • Central Bus. District-JDX
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  • Houston Municipal-SGR
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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