Cheap Flights from Des Moines, IA to Cancun from $149

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On Cheapflightsplus.com you will find 761 connecting flights from Des Moines to Cancun. You can compare airfare deals from 6 airlines and multiple travel sites from $149, book and save on cheap plane tickets and last minute offers. Also check out DSM-CUN flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Des Moines to Cancun Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $149 (one-way), $256 (round-trip).
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Best Flights from Des Moines to Cancun Today

Take a look at the list of non stop flights and flights with layovers from Des Moines to Cancun with the lowest price of $149. Take a look at the list of flights with layovers from Des Moines to Cancun from $149. There’re no direct flights. The fastest connecting flight – 5h 45m.
Price Departure Arrival Flight Duration Airline Flight
from $149
Find flight
06:30
Des Moines
Des Moines International Airport
 10:47+1 день
Cancun
Cancun Int
 28h 17m
layover
23h 44m - Houston
 Allegiant Air
G4437
NK1336
from $172
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09:39
Des Moines
Des Moines International Airport
 09:03+1 день
Cancun
Cancun Int
 23h 24m
layover
18h 11m - Miami
 Allegiant Air
G42156
NK1610
from $169
Find flight
13:13
Des Moines
Des Moines International Airport
 08:03+1 день
Cancun
Cancun Int
 18h 50m
layover
5h 51m - Nashville
7h 3m - Miami
 Allegiant Air
G4434
NK2030
NK1610
from $195
Find flight
08:35
Des Moines
Des Moines International Airport
 11:13+1 день
Cancun
Cancun Int
 26h 38m
layover
17h 55m - New York
1h 24m - Miami
 Allegiant Air
G4431
NK2005
NK527
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 18, 2025
Full flight schedule will help you in detecting at what time planes fly from Des Moines to Cancun. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
06:00 — 12:30
+1 day
06:00 — 09:49 G4446 Allegiant Air
Des Moines — Boston
23h 19m stop
09:07 — 12:30 AM5081 Aeromexico
Boston — Cancun
30h 30m
including layover
Find flight
from$216
06:30 — 10:47
+1 day
06:30 — 08:48 G4437 Allegiant Air
Des Moines — Houston
23h 44m stop
09:27 — 11:39 NK1336 Spirit Airlines
Houston — Cancun
28h 17m
including layover
Find flight
from$149
06:30 — 09:03
+1 day
06:30 — 10:40 G4466 Allegiant Air
Des Moines — Miami
21h 20m stop
08:00 — 09:03 NK1610 Spirit Airlines
Miami — Cancun
26h 33m
including layover
Find flight
from$160
06:30 — 11:21
+1 day
06:30 — 10:40 G4466 Allegiant Air
Des Moines — Miami
23h 36m stop
10:16 — 11:21 NK527 Spirit Airlines
Miami — Cancun
28h 51m
including layover
Find flight
from$160
06:30 — 11:13
+1 day
06:30 — 10:45 G4469 Allegiant Air
Des Moines — Miami
23h 38m stop
10:22 — 11:13 NK527 Spirit Airlines
Miami — Cancun
28h 43m
including layover
Find flight
from$192
06:30 — 08:03
+1 day
06:30 — 10:40 G4469 Allegiant Air
Des Moines — Miami
20h 20m stop
08:00 — 09:03 NK1610 Spirit Airlines
Miami — Cancun
25h 33m
including layover
Find flight
from$201
07:00 — 08:12
+1 day
07:00 — 10:45 G4456 Allegiant Air
Des Moines — Orlando
20h 25m stop
07:10 — 08:12 NK3642 Spirit Airlines
Orlando — Cancun
25h 12m
including layover
Find flight
from$178
07:00 — 08:12
+1 day
07:00 — 10:48 G4458 Allegiant Air
Des Moines — Orlando
20h 22m stop
07:10 — 08:12 NK3642 Spirit Airlines
Orlando — Cancun
25h 12m
including layover
Find flight
from$202
09:39 — 09:03
+1 day
09:39 — 13:49 G42156 Allegiant Air
Des Moines — Miami
18h 11m stop
08:00 — 09:03 NK1610 Spirit Airlines
Miami — Cancun
23h 24m
including layover
Find flight
from$172
13:13 — 09:55
+1 day
13:13 — 14:47 G4434 Allegiant Air
Des Moines — Nashville
16h 13m stop
07:00 — 09:55 VB355 VivaAerobus
Nashville — Cancun
20h 42m
including layover
Find flight
from$253
19:19 — 08:04
+1 day
19:19 — 23:04 G42850 Allegiant Air
Des Moines — Orlando
7h 46m stop
06:50 — 08:04 F9163 Frontier Airlines
Orlando — Cancun
12h 45m
including layover
Find flight
from$182
19:19 — 08:16
+1 day
19:19 — 23:04 G42850 Allegiant Air
Des Moines — Orlando
8h 6m stop
07:10 — 08:16 NK3642 Spirit Airlines
Orlando — Cancun
12h 57m
including layover
Find flight
from$191
19:21 — 08:16
+1 day
19:21 — 23:06 G41314 Allegiant Air
Des Moines — Orlando
8h 4m stop
07:10 — 08:16 NK3642 Spirit Airlines
Orlando — Cancun
12h 55m
including layover
Find flight
from$197
19:21 — 08:05
+1 day
19:21 — 23:06 G41314 Allegiant Air
Des Moines — Orlando
7h 44m stop
06:50 — 08:05 F9163 Frontier Airlines
Orlando — Cancun
12h 44m
including layover
Find flight
from$212
20:38 — 16:20
+1 day
20:38 — 21:48 F91677 Frontier Airlines
Des Moines — Denver
13h 25m stop
11:13 — 16:22 F970 Frontier Airlines
Denver — Cancun
19h 42m
including layover
Find flight
from$178
*Departure and arrival times - local. Updated on September 18, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Des Moines to Cancun depends on and how to choose the most interesting flight option for you.

Distance between Des Moines and Cancun is 2366 miles. Time difference between the cities is 1h. Airplanes depart 05:40 to 22:31 from 1 Des Moines airport and arrive 05:40 to 22:31 to 2 Cancun airports. Average flight time is 24h 49m.

  • The fastest flight 5h 45m
  • Average flight time 24h 49m
  • The earliest flight 05:40
  • The latest flight 22:31
  • Distance 1471 ml

The cheapest months to travel to Cancun are july (from 149 $), june (from 169 $), august (from 172 $).

The most expensive months are december (from 719 $), february (from 588 $), october (from 468 $).

What is the lowest airfare Des Moines to Cancun?

The cheapest plane ticket found by our users is $149. This airfare is for economy class on one-way G4437 flight by Allegiant Air for August 7, 2025 which leaves Des Moines International Airport in Des Moines at 06:30 am and arrives at Cancun Cancun Int at 10:47.

Economy class
$149
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Business class
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First class
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Popular Airlines on the Route

The flight Des Moines — Cancun is served by 6 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Air Canada - 209 departures per week at the price of from $ 389 . And the most expensive tickets are offered by United Airlines airline - from $ 2905.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 761 flights with layovers on the route. The fastest connecting flight is AM3588 by Aeromexico takes 5h 45m and the cheapest is G4437 by Allegiant Air for $149.

  • AC - Air Canada
    from $389
    Find
  • F9 - Frontier Airlines
    from $178
    Find
  • AM - Aeromexico
    from $257
    Find
  • UA - United Airlines
    from $267
    Find
  • WS - WestJet
    from $540
    Find
  • G4 - Allegiant Air
    from $149
    Find
See more connecting flights

Airports

You can fly from Des Moines to Cancun from 1 airports (Des Moines International Airport).

Des Moines airports

  • Des Moines International Airport-DSM
    from $149
    Find

Cancun airports

  • Cancun Int-CUN
    Find
  • Puerto Juarez-PJZ
    Find

Airplanes

There are flights to Cancun from Des Moines by 6 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Des Moines

You may also consider searching for discounted plane tickets to some other popular places from Des Moines within United States.

Top International Destinations from Des Moines

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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