Cheap Flights from Des Moines, IA to Cancun from $170

On Cheapflightsplus.com you will find 484 connecting flights from Des Moines to Cancun. You can compare airfare deals from 6 airlines and multiple travel sites from $170, book and save on cheap plane tickets and last minute offers. Also check out DSM-CUN flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Des Moines to Cancun Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $170 (one-way), $292 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Des Moines to Cancun. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
05:55 — 13:46
05:55 — 09:05 AM3607 Aeromexico
Des Moines — Atlanta
2h stop
11:05 — 13:46 AM5319 Aeromexico
Atlanta — Cancun
6h 51m
including layover
Find flight
from$338
05:55 — 15:15
05:55 — 09:05 AM3607 Aeromexico
Des Moines — Atlanta
3h 34m stop
12:39 — 15:15 AM5533 Aeromexico
Atlanta — Cancun
8h 20m
including layover
Find flight
from$338
06:00 — 14:18
06:00 — 07:04 UA497 United Airlines
Des Moines — Denver
1h 16m stop
08:20 — 14:18 UA1119 United Airlines
Denver — Cancun
7h 18m
including layover
Find flight
from$339
06:00 — 15:43
06:00 — 07:04 UA497 United Airlines
Des Moines — Denver
2h 39m stop
09:43 — 15:43 UA2030 United Airlines
Denver — Cancun
8h 43m
including layover
Find flight
from$371
07:00 — 15:05
07:00 — 08:20 AM4366 Aeromexico
Des Moines — Minneapolis
1h 45m stop
10:05 — 15:05 AM5018 Aeromexico
Minneapolis — Cancun
7h 5m
including layover
Find flight
from$338
07:30 — 12:40
+1 day
07:30 — 11:05 G4431 Allegiant Air
Des Moines — New York
21h 15m stop
08:20 — 12:40 AM4594 Aeromexico
New York — Cancun
28h 10m
including layover
Find flight
from$331
08:00 — 15:33
08:00 — 09:35 UA1363 United Airlines
Des Moines — Chicago
1h 8m stop
10:36 — 15:33 UA1659 United Airlines
Chicago — Cancun
6h 33m
including layover
Find flight
from$334
08:00 — 15:59
08:00 — 10:33 UA735 United Airlines
Des Moines — Houston
1h 58m stop
12:35 — 15:59 UA1167 United Airlines
Houston — Cancun
6h 59m
including layover
Find flight
from$334
09:00 — 09:14
+1 day
09:00 — 12:50 G4464 Allegiant Air
Des Moines — Orlando
18h 10m stop
07:00 — 09:14 NK3642 Spirit Airlines
Orlando — Cancun
23h 14m
including layover
Find flight
from$278
09:00 — 14:18
+1 day
09:00 — 10:15 UA581 United Airlines
Des Moines — Denver
22h 10m stop
08:20 — 14:18 UA1119 United Airlines
Denver — Cancun
28h 18m
including layover
Find flight
from$358
10:00 — 12:05
+1 day
10:00 — 14:11 G4452 Allegiant Air
Des Moines — Miami
20h 4m stop
10:15 — 12:05 NK527 Spirit Airlines
Miami — Cancun
25h 5m
including layover
Find flight
from$422
11:35 — 14:10
+1 day
11:25 — 12:53 UA2306 United Airlines
Des Moines — Chicago
20h 3m stop
09:13 — 14:10 UA1198 United Airlines
Chicago — Cancun
25h 35m
including layover
Find flight
from$413
11:45 — 21:02
11:19 — 14:29 AM3608 Aeromexico
Des Moines — Atlanta
3h 29m stop
18:26 — 21:03 AM3072 Aeromexico
Atlanta — Cancun
8h 17m
including layover
Find flight
from$314
13:45 — 14:18
+1 day
13:45 — 14:51 UA5669 United Airlines
Des Moines — Denver
17h 29m stop
08:20 — 14:18 UA1119 United Airlines
Denver — Cancun
23h 33m
including layover
Find flight
from$397
13:49 — 14:18
+1 day
13:45 — 14:51 UA5835 United Airlines
Des Moines — Denver
17h 21m stop
08:20 — 14:18 UA1119 United Airlines
Denver — Cancun
23h 29m
including layover
Find flight
from$358
14:24 — 21:03
14:24 — 17:27 AM4644 Aeromexico
Des Moines — Atlanta
59m stop
18:26 — 21:03 AM3072 Aeromexico
Atlanta — Cancun
5h 39m
including layover
Find flight
from$314
14:59 — 09:14
+1 day
14:59 — 18:49 G4466 Allegiant Air
Des Moines — Orlando
12h 11m stop
07:00 — 09:14 NK3642 Spirit Airlines
Orlando — Cancun
17h 15m
including layover
Find flight
from$309
15:05 — 13:34
+1 day
15:00 — 17:35 UA6033 United Airlines
Des Moines — Houston
16h 22m stop
10:10 — 13:34 UA1014 United Airlines
Houston — Cancun
21h 29m
including layover
Find flight
from$341
15:05 — 15:59
+1 day
15:00 — 17:35 UA6033 United Airlines
Des Moines — Houston
18h 47m stop
12:35 — 15:59 UA1167 United Airlines
Houston — Cancun
23h 54m
including layover
Find flight
from$341
16:10 — 11:25
+1 day
15:00 — 17:35 UA6033 United Airlines
Des Moines — Houston
13h 9m stop
08:02 — 11:25 UA1619 United Airlines
Houston — Cancun
18h 15m
including layover
Find flight
from$395
16:10 — 12:54
+1 day
15:00 — 17:35 UA6033 United Airlines
Des Moines — Houston
14h 38m stop
09:31 — 12:54 UA1018 United Airlines
Houston — Cancun
19h 44m
including layover
Find flight
from$481
17:15 — 14:18
+1 day
17:10 — 18:19 UA1781 United Airlines
Des Moines — Denver
14h stop
08:20 — 14:18 UA1119 United Airlines
Denver — Cancun
20h 3m
including layover
Find flight
from$341
17:15 — 15:43
+1 day
17:10 — 18:19 UA1781 United Airlines
Des Moines — Denver
15h 23m stop
09:43 — 15:43 UA2030 United Airlines
Denver — Cancun
21h 28m
including layover
Find flight
from$341
18:45 — 13:33
+1 day
18:45 — 20:22 UA5286 United Airlines
Des Moines — Chicago
12h 20m stop
08:42 — 13:33 UA1656 United Airlines
Chicago — Cancun
17h 48m
including layover
Find flight
from$341
18:45 — 14:10
+1 day
18:45 — 20:22 UA5286 United Airlines
Des Moines — Chicago
12h 51m stop
09:13 — 14:10 UA1198 United Airlines
Chicago — Cancun
18h 25m
including layover
Find flight
from$341
21:21 — 13:08
+1 day
17:07 — 18:18 F91677 Frontier Airlines
Des Moines — Denver
8h 40m stop
07:02 — 13:08 F970 Frontier Airlines
Denver — Cancun
14h 47m
including layover
Find flight
from$170
*Departure and arrival times - local. Updated on May 9, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Des Moines to Cancun depends on and how to choose the most interesting flight option for you.

Distance between Des Moines and Cancun is 2366 miles. Time difference between the cities is 1h. Airplanes depart 05:40 to 21:21 from 1 Des Moines airport and arrive 05:40 to 21:21 to 2 Cancun airports. Average flight time is 21h 29m.

  • The fastest flight 5h 30m
  • Average flight time 21h 29m
  • The earliest flight 05:40
  • The latest flight 21:21
  • Distance 1471 ml

The cheapest months to travel to Cancun are february (from 170 $), january (from 273 $), december (from 278 $).

The most expensive months are november (from 292 $), december (from 278 $), january (from 273 $).

What is the lowest airfare Des Moines to Cancun?

The cheapest plane ticket found by our users is $170. This airfare is for economy class on one-way F91677 flight by Frontier Airlines for February 21, 2025 which leaves Des Moines International Airport in Des Moines at 21:21 am and arrives at Cancun Cancun Int at 13:08.

Economy class
$170
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Business class
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First class
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Popular Airlines on the Route

The flight Des Moines — Cancun is served by 6 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Air Canada - 93 departures per week at the price of from $ 383 . And the most expensive tickets are offered by Air Canada airline - from $ 2464.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 484 flights with layovers on the route. The fastest connecting flight is AM3607 by Aeromexico takes 5h 30m and the cheapest is F91677 by Frontier Airlines for $170.

  • AC - Air Canada
    from $383
    Find
  • F9 - Frontier Airlines
    from $170
    Find
  • AM - Aeromexico
    from $314
    Find
  • UA - United Airlines
    from $334
    Find
  • WS - WestJet
    from $547
    Find
  • G4 - Allegiant Air
    from $273
    Find
See more connecting flights

Airports

You can fly from Des Moines to Cancun from 1 airports (Des Moines International Airport).

Des Moines airports

  • Des Moines International Airport-DSM
    from $170
    Find

Cancun airports

  • Cancun Int-CUN
    Find
  • Puerto Juarez-PJZ
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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