Cheap Flights from Des Moines, IA to Cancun from $150

On Cheapflightsplus.com you will find 761 connecting flights from Des Moines to Cancun. You can compare airfare deals from 6 airlines and multiple travel sites from $150, book and save on cheap plane tickets and last minute offers. Also check out DSM-CUN flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Des Moines to Cancun depends on and how to choose the most interesting flight option for you.

Distance between Des Moines and Cancun is 2366 miles. Time difference between the cities is 1h. Airplanes depart 05:40 to 22:31 from 1 Des Moines airport and arrive 05:40 to 22:31 to 2 Cancun airports. Average flight time is 24h 49m.

  • The fastest flight 5h 45m
  • Average flight time 24h 49m
  • The earliest flight 05:40
  • The latest flight 22:31
  • Distance 1471 ml

The cheapest months to travel to Cancun are july (from 150 $), june (from 170 $), august (from 173 $).

The most expensive months are december (from 723 $), february (from 592 $), september (from 453 $).

What is the lowest airfare Des Moines to Cancun?

The cheapest plane ticket found by our users is $150. This airfare is for economy class on one-way G4437 flight by Allegiant Air for August 7, 2025 which leaves Des Moines International Airport in Des Moines at 06:30 am and arrives at Cancun Cancun Int at 10:47.

Economy class
$150
Find
Business class
?
Find
First class
?
Find

Flight Schedule Des Moines (Iowa) to Cancun

06:00 — 12:30+1day
30h 30m flight time
Find flight
from$217
06:00 — 09:49 Des Moines — Boston
G4446 Allegiant Air
23h 19m stop
09:07 — 12:30 Boston — Cancun
AM5081 Aeromexico
06:30 — 10:47+1day
28h 17m flight time
Find flight
from$150
06:30 — 08:48 Des Moines — Houston
G4437 Allegiant Air
23h 44m stop
09:27 — 11:39 Houston — Cancun
NK1336 Spirit Airlines
06:30 — 09:03+1day
26h 33m flight time
Find flight
from$161
06:30 — 10:40 Des Moines — Miami
G4466 Allegiant Air
21h 20m stop
08:00 — 09:03 Miami — Cancun
NK1610 Spirit Airlines
06:30 — 11:21+1day
28h 51m flight time
Find flight
from$161
06:30 — 10:40 Des Moines — Miami
G4466 Allegiant Air
23h 36m stop
10:16 — 11:21 Miami — Cancun
NK527 Spirit Airlines
06:30 — 11:13+1day
28h 43m flight time
Find flight
from$193
06:30 — 10:45 Des Moines — Miami
G4469 Allegiant Air
23h 38m stop
10:22 — 11:13 Miami — Cancun
NK527 Spirit Airlines
06:30 — 08:03+1day
25h 33m flight time
Find flight
from$202
06:30 — 10:40 Des Moines — Miami
G4469 Allegiant Air
20h 20m stop
08:00 — 09:03 Miami — Cancun
NK1610 Spirit Airlines
07:00 — 08:12+1day
25h 12m flight time
Find flight
from$179
07:00 — 10:45 Des Moines — Orlando
G4456 Allegiant Air
20h 25m stop
07:10 — 08:12 Orlando — Cancun
NK3642 Spirit Airlines
07:00 — 08:12+1day
25h 12m flight time
Find flight
from$203
07:00 — 10:48 Des Moines — Orlando
G4458 Allegiant Air
20h 22m stop
07:10 — 08:12 Orlando — Cancun
NK3642 Spirit Airlines
09:39 — 09:03+1day
23h 24m flight time
Find flight
from$173
09:39 — 13:49 Des Moines — Miami
G42156 Allegiant Air
18h 11m stop
08:00 — 09:03 Miami — Cancun
NK1610 Spirit Airlines
13:13 — 09:55+1day
20h 42m flight time
Find flight
from$255
13:13 — 14:47 Des Moines — Nashville
G4434 Allegiant Air
16h 13m stop
07:00 — 09:55 Nashville — Cancun
VB355 VivaAerobus
19:19 — 08:04+1day
12h 45m flight time
Find flight
from$183
19:19 — 23:04 Des Moines — Orlando
G42850 Allegiant Air
7h 46m stop
06:50 — 08:04 Orlando — Cancun
F9163 Frontier Airlines
19:19 — 08:16+1day
12h 57m flight time
Find flight
from$192
19:19 — 23:04 Des Moines — Orlando
G42850 Allegiant Air
8h 6m stop
07:10 — 08:16 Orlando — Cancun
NK3642 Spirit Airlines
19:21 — 08:16+1day
12h 55m flight time
Find flight
from$198
19:21 — 23:06 Des Moines — Orlando
G41314 Allegiant Air
8h 4m stop
07:10 — 08:16 Orlando — Cancun
NK3642 Spirit Airlines
19:21 — 08:05+1day
12h 44m flight time
Find flight
from$213
19:21 — 23:06 Des Moines — Orlando
G41314 Allegiant Air
7h 44m stop
06:50 — 08:05 Orlando — Cancun
F9163 Frontier Airlines
20:38 — 16:20+1day
19h 42m flight time
Find flight
from$179
20:38 — 21:48 Des Moines — Denver
F91677 Frontier Airlines
13h 25m stop
11:13 — 16:22 Denver — Cancun
F970 Frontier Airlines
Full flight schedule will help you in detecting at what time planes fly from Des Moines to Cancun. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on October 19, 2025.

Popular Airlines on the Route

The flight Des Moines — Cancun is served by 6 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Air Canada - 209 departures per week at the price of from $ 374 . And the most expensive tickets are offered by United Airlines airline - from $ 2921.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 761 flights with layovers on the route. The fastest connecting flight is AM3588 by Aeromexico takes 5h 45m and the cheapest is G4437 by Allegiant Air for $150.

  • AC - Air Canada
    from $374
    Find
  • F9 - Frontier Airlines
    from $179
    Find
  • AM - Aeromexico
    from $258
    Find
  • UA - United Airlines
    from $268
    Find
  • WS - WestJet
    from $543
    Find
  • G4 - Allegiant Air
    from $150
    Find
See more connecting flights

Airports

You can fly from Des Moines to Cancun from 1 airports (Des Moines International Airport).

Des Moines airports

  • Des Moines International Airport-DSM
    from $150
    Find

Cancun airports

  • Cancun Int-CUN
    Find
  • Puerto Juarez-PJZ
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back