Cheap Flights from Des Moines, IA to San Diego, CA from $76

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On Cheapflightsplus.com you will find 89 connecting flights from Des Moines to San Diego. You can compare airfare deals from 4 airlines and multiple travel sites from $76, book and save on cheap plane tickets and last minute offers. Also check out DSM-SAN flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Des Moines to San Diego Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $76 (one-way), $130 (round-trip).

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Best Flights from Des Moines to San Diego Today

Take a look at the list of non stop flights and flights with layovers from Des Moines to San Diego with the lowest price of $76. Take a look at the list of flights with layovers from Des Moines to San Diego from $76. There’re no direct flights. The fastest connecting flight – 5h 25m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $76 Find flight	21:21 Des Moines Des Moines International Airport	06:24+1 день San Diego San Diego	11h 3m layover 6h 41m - Denver	Frontier Airlines	F91677 F92817
from $111 Find flight	15:35 Des Moines Des Moines International Airport	23:52 San Diego San Diego	10h 17m layover 5h 38m - Las Vegas	Allegiant Air	G4451 NK191
from $257 Find flight	06:00 Des Moines Des Moines International Airport	09:28 San Diego San Diego	5h 28m layover 0h 56m - Denver	United Airlines	UA497 UA2309
from $257 Find flight	13:49 Des Moines Des Moines International Airport	17:25 San Diego San Diego	5h 36m layover 0h 56m - Denver	United Airlines	UA5835 UA1281
from $257 Find flight	09:00 Des Moines Des Moines International Airport	12:53 San Diego San Diego	5h 53m layover 1h 10m - Denver	United Airlines	UA581 UA2381
from $257 Find flight	14:37 Des Moines Des Moines International Airport	20:05 San Diego San Diego	7h 28m layover 2h 56m - Phoenix	Alaska Airlines	AS4135 AS4295
from $257 Find flight	08:00 Des Moines Des Moines International Airport	13:50 San Diego San Diego	7h 50m layover 1h 47m - Houston	United Airlines	UA735 UA2486
from $257 Find flight	15:23 Des Moines Des Moines International Airport	22:22 San Diego San Diego	8h 59m layover 2h 59m - Chicago	United Airlines	UA1568 UA2735
from $257 Find flight	15:23 Des Moines Des Moines International Airport	22:22 San Diego San Diego	8h 59m layover 2h 56m - Chicago	United Airlines	UA3447 UA2735
from $257 Find flight	11:29 Des Moines Des Moines International Airport	18:51 San Diego San Diego	9h 22m layover 3h 20m - Chicago	United Airlines	UA3417 UA2080
from $155 Find flight	07:00 Des Moines Des Moines International Airport	22:17 San Diego San Diego	17h 17m layover 5h 3m - Santa Ana 6h 5m - Las Vegas	Allegiant Air	G4457 NK874 NK1496
from $159 Find flight	07:00 Des Moines Des Moines International Airport	18:15 San Diego San Diego	13h 15m layover 5h 3m - Santa Ana 1h 57m - Las Vegas	Allegiant Air	G4457 NK874 NK2907
from $185 Find flight	14:29 Des Moines Des Moines International Airport	08:13+1 день San Diego San Diego	19h 44m layover 5h 33m - Phoenix 8h 38m - Las Vegas	Allegiant Air	G42062 NK536 NK375
from $210 Find flight	08:00 Des Moines Des Moines International Airport	23:52 San Diego San Diego	17h 52m layover 3h 34m - Miami 4h 9m - Las Vegas	Allegiant Air	G4436 NK201 NK191
from $248 Find flight	08:30 Des Moines Des Moines International Airport	22:17 San Diego San Diego	15h 47m layover 4h 1m - Austin 5h 11m - Las Vegas	Allegiant Air	G42056 NK869 NK1496
from $252 Find flight	08:30 Des Moines Des Moines International Airport	18:15 San Diego San Diego	11h 45m layover 4h 1m - Austin 1h 3m - Las Vegas	Allegiant Air	G42056 NK869 NK2907

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on December 04, 2024

Flight Schedule Des Moines (Iowa) to San Diego (California)

Full flight schedule will help you in detecting at what time planes fly from Des Moines to San Diego. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
05:00 — 11:34	05:00 — 07:35 AS6332 Alaska Airlines Des Moines — Phoenix 3h 38m stop 11:13 — 11:34 AS4295 Alaska Airlines Phoenix — San Diego	8h 34m including layover	Find flight from$258
05:45 — 09:29	05:45 — 07:02 UA4700 United Airlines Des Moines — Denver 56m stop 08:00 — 09:30 UA2309 United Airlines Denver — San Diego	5h 44m including layover	Find flight from$259
06:00 — 09:28	06:00 — 07:04 UA497 United Airlines Des Moines — Denver 56m stop 08:05 — 09:33 UA2309 United Airlines Denver — San Diego	5h 28m including layover	Find flight from$257
06:00 — 11:18	06:00 — 07:04 UA497 United Airlines Des Moines — Denver 2h 46m stop 10:20 — 11:48 UA1842 United Airlines Denver — San Diego	7h 18m including layover	Find flight from$257
09:00 — 12:53	09:02 — 10:17 UA581 United Airlines Des Moines — Denver 1h 10m stop 11:40 — 13:08 UA2381 United Airlines Denver — San Diego	5h 53m including layover	Find flight from$257
09:00 — 11:18 +1 day	09:02 — 10:17 UA581 United Airlines Des Moines — Denver 23h 35m stop 10:15 — 11:43 UA1842 United Airlines Denver — San Diego	28h 18m including layover	Find flight from$314
11:29 — 18:51	11:29 — 13:00 UA3417 United Airlines Des Moines — Chicago 3h 20m stop 16:20 — 18:51 UA2080 United Airlines Chicago — San Diego	9h 22m including layover	Find flight from$257
11:29 — 19:00	11:29 — 12:57 UA1373 United Airlines Des Moines — Chicago 3h 23m stop 16:20 — 19:00 UA2184 United Airlines Chicago — San Diego	9h 31m including layover	Find flight from$262
13:45 — 20:53	13:45 — 14:51 UA5835 United Airlines Des Moines — Denver 4h 34m stop 19:25 — 20:53 UA540 United Airlines Denver — San Diego	9h 8m including layover	Find flight from$310
13:49 — 17:25	13:45 — 14:51 UA5835 United Airlines Des Moines — Denver 56m stop 16:01 — 17:29 UA1281 United Airlines Denver — San Diego	5h 36m including layover	Find flight from$257
14:37 — 20:05	14:37 — 16:52 AS4135 Alaska Airlines Des Moines — Phoenix 2h 56m stop 19:48 — 20:05 AS4295 Alaska Airlines Phoenix — San Diego	7h 28m including layover	Find flight from$257
15:23 — 22:22	15:23 — 16:51 UA1568 United Airlines Des Moines — Chicago 2h 59m stop 19:50 — 22:22 UA2735 United Airlines Chicago — San Diego	8h 59m including layover	Find flight from$257
15:35 — 23:52	15:35 — 17:03 G4451 Allegiant Air Des Moines — Las Vegas 5h 38m stop 22:41 — 23:52 NK191 Spirit Airlines Las Vegas — San Diego	10h 17m including layover	Find flight from$111
17:07 — 23:49	18:51 — 19:57 F91677 Frontier Airlines Des Moines — Denver 3h 57m stop 19:56 — 21:25 F94989 Frontier Airlines Denver — San Diego	8h 42m including layover	Find flight from$142
17:13 — 22:40	17:13 — 18:20 UA1781 United Airlines Des Moines — Denver 2h 45m stop 21:05 — 22:40 UA486 United Airlines Denver — San Diego	7h 27m including layover	Find flight from$262
21:21 — 06:24 +1 day	18:51 — 19:57 F91677 Frontier Airlines Des Moines — Denver 6h 41m stop 05:35 — 07:05 F92817 Frontier Airlines Denver — San Diego	11h 3m including layover	Find flight from$76
07:00 — 22:17	07:00 — 08:45 G4457 Allegiant Air Des Moines — Santa Ana 5h 3m stop 13:48 — 15:00 NK874 Spirit Airlines Santa Ana — Las Vegas 6h 5m stop 21:05 — 22:17 NK1496 Spirit Airlines Las Vegas — San Diego	17h 17m including layover	Find flight from$155
07:00 — 18:15	07:00 — 08:45 G4457 Allegiant Air Des Moines — Santa Ana 5h 3m stop 13:48 — 15:00 NK874 Spirit Airlines Santa Ana — Las Vegas 1h 57m stop 16:57 — 18:15 NK2907 Spirit Airlines Las Vegas — San Diego	13h 15m including layover	Find flight from$159
08:00 — 23:52	08:00 — 12:22 G4436 Allegiant Air Des Moines — Miami 3h 34m stop 15:56 — 18:32 NK201 Spirit Airlines Miami — Las Vegas 4h 9m stop 22:41 — 23:52 NK191 Spirit Airlines Las Vegas — San Diego	17h 52m including layover	Find flight from$210
08:30 — 22:17	08:30 — 10:48 G42056 Allegiant Air Des Moines — Austin 4h 1m stop 14:49 — 15:54 NK869 Spirit Airlines Austin — Las Vegas 5h 11m stop 21:05 — 22:17 NK1496 Spirit Airlines Las Vegas — San Diego	15h 47m including layover	Find flight from$248
12:15 — 23:59	12:15 — 13:43 AS6532 Alaska Airlines Des Moines — Chicago 3h 45m stop 17:28 — 20:11 AS353 Alaska Airlines Chicago — Seattle 1h 5m stop 21:16 — 23:59 AS1164 Alaska Airlines Seattle — San Diego	13h 44m including layover	Find flight from$262
14:29 — 08:13 +1 day	14:29 — 16:38 G42062 Allegiant Air Des Moines — Phoenix 5h 33m stop 22:11 — 22:22 NK536 Spirit Airlines Phoenix — Las Vegas 8h 38m stop 07:00 — 08:13 NK375 Spirit Airlines Las Vegas — San Diego	19h 44m including layover	Find flight from$185

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on December 4, 2024

Flight Information

Below we will explain in detail what the flights cost on the destination from Des Moines to San Diego depends on and how to choose the most interesting flight option for you.

Distance between Des Moines and San Diego is 2295 miles. Time difference between the cities is 2h. Airplanes depart 05:00 to 21:21 from 1 Des Moines airport and arrive 05:00 to 21:21 to 11 San Diego airports. Average flight time is 12h 19m.

The fastest flight 5h 25m
Average flight time 12h 19m
The earliest flight 05:00
The latest flight 21:21
Distance 1427 ml

The cheapest months to travel to San Diego are november (from 56 $), february (from 76 $), january (from 111 $).

The most expensive months are december (from 142 $), january (from 111 $), february (from 76 $).

What is the lowest airfare Des Moines to San Diego?

The cheapest plane ticket found by our users is $76. This airfare is for economy class on one-way F91677 flight by Frontier Airlines for February 21, 2025 which leaves Des Moines International Airport in Des Moines at 21:21 am and arrives at San Diego San Diego at 06:24.

Economy class

$76

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Popular Airlines on the Route

The flight Des Moines — San Diego is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 22 departures per week at the price of from $ 257 . And the most expensive tickets are offered by Alaska Airlines airline - from $ 667.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 89 flights with layovers on the route. The fastest connecting flight is UA1781 by United Airlines takes 5h 25m and the cheapest is F91677 by Frontier Airlines for $76.

AS - Alaska Airlines

from $257

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F9 - Frontier Airlines

from $76

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UA - United Airlines

from $257

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G4 - Allegiant Air

from $111

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Airports

You can fly from Des Moines to San Diego from 1 airports (Des Moines International Airport).

Des Moines airports

Des Moines International Airport-DSM

from $76
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San Diego airports

San Diego-SAN

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San Diego Regional-USA

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Gillespie Field-SEE

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Golden Triangle Reg.-GTR

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El Cajon-CJN

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Lowndes County-UBS

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Miramar NAS-NKX

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Montgomery Field-MYF

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North Island NAS-NZY

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Brown Field Municipal-SDM

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AFB-CBM

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Airplanes

There are flights to San Diego from Des Moines by 4 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Des Moines

You may also consider searching for discounted plane tickets to some other popular places from Des Moines within United States.

Des Moines — Denver

from $54

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Des Moines — Philadelphia

from $71

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Des Moines — Colorado Springs

from $73

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Des Moines — San Antonio

from $61

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Des Moines — Orlando

from $74

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Des Moines — Chicago

from $72

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Des Moines — Indianapolis

from $62

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Des Moines — Boston

from $65

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Des Moines — San Diego

from $58

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Des Moines — El Paso

from $73

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Top International Destinations from Des Moines

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Des Moines — Guadalajara

from $71

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Des Moines — Cancun

from $77

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Des Moines — London

from $70

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How to book a plane ticket yourself?

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