Cheap Flights from Des Moines, IA to San Diego, CA from $58

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On Cheapflightsplus.com you will find 120 connecting flights from Des Moines to San Diego. You can compare airfare deals from 7 airlines and multiple travel sites from $50, book and save on cheap plane tickets and last minute offers. Also check out DSM-SAN flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Des Moines to San Diego Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $58 (one-way), $99 (round-trip).

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Best Flights from Des Moines to San Diego Today

Take a look at the list of non stop flights and flights with layovers from Des Moines to San Diego with the lowest price of $50. Take a look at the list of flights with layovers from Des Moines to San Diego from $50. There’re no direct flights. The fastest connecting flight – 5h.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $50 Find flight	17:36 Des Moines Des Moines International Airport	20:59 San Diego San Diego	5h 23m layover 0h 55m - Denver	United Airlines	UA5564 UA540
from $50 Find flight	07:00 Des Moines Des Moines International Airport	11:28 San Diego San Diego	6h 28m layover 1h 0m - Chicago	United Airlines	UA5680 UA348
from $50 Find flight	07:53 Des Moines Des Moines International Airport	12:47 San Diego San Diego	6h 54m layover 2h 44m - Denver	United Airlines	UA771 UA1108
from $50 Find flight	15:09 Des Moines Des Moines International Airport	22:40 San Diego San Diego	9h 31m layover 3h 56m - Chicago	United Airlines	UA4508 UA308
from $51 Find flight	06:30 Des Moines Des Moines International Airport	10:46 San Diego San Diego	6h 16m layover 0h 51m - Houston	United Airlines	UA6115 UA2358
from $51 Find flight	06:59 Des Moines Des Moines International Airport	13:24 San Diego San Diego	8h 25m layover 1h 15m - Charlotte	American Airlines	AA4377 AA1676

from $52 Find flight	15:45 Des Moines Des Moines International Airport	18:45 San Diego San Diego	5h 0m layover 0h 54m - Phoenix	American Airlines	AA2996 AA559
from $52 Find flight	08:26 Des Moines Des Moines International Airport	11:34 San Diego San Diego	5h 8m layover 0h 59m - Phoenix	American Airlines	AA1795 AA2671
from $52 Find flight	09:30 Des Moines Des Moines International Airport	13:42 San Diego San Diego	6h 12m layover 1h 24m - Dallas	American Airlines	AA2326 AA1229
from $52 Find flight	15:30 Des Moines Des Moines International Airport	19:44 San Diego San Diego	6h 14m layover 1h 25m - Dallas	American Airlines	AA1536 AA1243
from $52 Find flight	06:00 Des Moines Des Moines International Airport	11:45 San Diego San Diego	7h 45m layover 2h 50m - Dallas	American Airlines	AA5738 AA679
from $52 Find flight	06:17 Des Moines Des Moines International Airport	12:33 San Diego San Diego	8h 16m layover 2h 30m - Chicago	American Airlines	AA3252 AA1553

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 23, 2023

Flight Schedule Des Moines (Iowa) to San Diego (California)

Full flight schedule will help you in detecting at what time planes fly from Des Moines to San Diego. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
06:30 — 10:46	06:30 — 08:44 UA6115 United Airlines Des Moines — Houston 51m stop 09:35 — 10:46 UA2358 United Airlines Houston — San Diego	6h 16m including layover	Find flight from$51
06:59 — 13:24	06:59 — 10:25 AA4377 American Airlines Des Moines — Charlotte 1h 15m stop 11:40 — 13:24 AA1676 American Airlines Charlotte — San Diego	8h 25m including layover	Find flight from$51
07:00 — 11:28	07:00 — 08:15 UA5680 United Airlines Des Moines — Chicago 1h stop 09:15 — 11:28 UA348 United Airlines Chicago — San Diego	6h 28m including layover	Find flight from$50
07:53 — 12:47	07:53 — 08:41 UA771 United Airlines Des Moines — Denver 2h 44m stop 11:25 — 12:47 UA1108 United Airlines Denver — San Diego	6h 54m including layover	Find flight from$50
08:26 — 11:34	08:26 — 09:20 AA1795 American Airlines Des Moines — Phoenix 59m stop 10:19 — 11:34 AA2671 American Airlines Phoenix — San Diego	5h 8m including layover	Find flight from$52
08:37 — 17:09	08:37 — 10:05 UA3591 United Airlines Des Moines — Chicago 4h 56m stop 15:01 — 17:09 NK563 Spirit Airlines Chicago — San Diego	10h 32m including layover	Find flight from$83
11:58 — 20:10	11:58 — 15:20 AA5421 American Airlines Des Moines — Charlotte 3h 5m stop 18:25 — 20:10 AA1740 American Airlines Charlotte — San Diego	10h 12m including layover	Find flight from$51
12:30 — 16:05	12:30 — 13:25 WN1596 Southwest Airlines Des Moines — Denver 1h 20m stop 14:45 — 16:05 WN407 Southwest Airlines Denver — San Diego	5h 35m including layover	Find flight from$94
12:30 — 18:15	12:30 — 13:25 WN1596 Southwest Airlines Des Moines — Denver 3h 30m stop 16:55 — 18:15 WN101 Southwest Airlines Denver — San Diego	7h 45m including layover	Find flight from$95
15:09 — 22:40	15:09 — 16:29 UA4508 United Airlines Des Moines — Chicago 3h 56m stop 20:25 — 22:40 UA308 United Airlines Chicago — San Diego	9h 31m including layover	Find flight from$50
15:30 — 19:44	15:30 — 17:20 AA1536 American Airlines Des Moines — Dallas 1h 25m stop 18:45 — 19:44 AA1243 American Airlines Dallas — San Diego	6h 14m including layover	Find flight from$52
16:17 — 22:35	16:17 — 17:45 AA2968 American Airlines Des Moines — Chicago 2h 35m stop 20:20 — 22:35 AA1457 American Airlines Chicago — San Diego	8h 18m including layover	Find flight from$52
16:17 — 17:09 +1 day	16:17 — 17:45 AA2968 American Airlines Des Moines — Chicago 21h 16m stop 15:01 — 17:09 NK563 Spirit Airlines Chicago — San Diego	26h 52m including layover	Find flight from$83
17:30 — 21:34	17:30 — 19:27 AA5832 American Airlines Des Moines — Dallas 1h 13m stop 20:40 — 21:34 AA2741 American Airlines Dallas — San Diego	6h 4m including layover	Find flight from$53
17:36 — 20:59	17:36 — 18:40 UA5564 United Airlines Des Moines — Denver 55m stop 19:35 — 20:59 UA540 United Airlines Denver — San Diego	5h 23m including layover	Find flight from$50
18:10 — 23:41	18:10 — 19:05 F9155 Frontier Airlines Des Moines — Denver 3h 15m stop 22:20 — 23:41 F9551 Frontier Airlines Denver — San Diego	7h 31m including layover	Find flight from$69
21:31 — 10:34 +1 day	21:31 — 22:34 G42455 Allegiant Air Des Moines — Las Vegas 10h 53m stop 09:27 — 10:34 NK429 Spirit Airlines Las Vegas — San Diego	15h 3m including layover	Find flight from$94
09:30 — 18:45	09:30 — 11:21 AA2326 American Airlines Des Moines — Dallas 2h 39m stop 14:00 — 14:24 AA526 American Airlines Dallas — Phoenix 3h 12m stop 17:36 — 18:45 AA559 American Airlines Phoenix — San Diego	11h 15m including layover	Find flight from$50
09:30 — 18:45	09:30 — 11:21 AA2326 American Airlines Des Moines — Dallas 3h 18m stop 14:39 — 15:04 AA2259 American Airlines Dallas — Phoenix 2h 32m stop 17:36 — 18:45 AA559 American Airlines Phoenix — San Diego	11h 15m including layover	Find flight from$50
11:50 — 18:30	11:50 — 13:15 UA4417 United Airlines Des Moines — Chicago 1h 12m stop 14:27 — 16:50 UA1969 United Airlines Chicago — Los Angeles 50m stop 17:40 — 18:30 UA5247 United Airlines Los Angeles — San Diego	8h 40m including layover	Find flight from$97
13:05 — 22:15	13:05 — 14:17 DL4647 Delta Air Lines Inc. Des Moines — Minneapolis 2h 16m stop 16:33 — 20:00 DL1736 Delta Air Lines Inc. Minneapolis — Atlanta 59m stop 20:59 — 22:15 DL1200 Delta Air Lines Inc. Atlanta — San Diego	11h 10m including layover	Find flight from$102
13:05 — 20:56	13:05 — 14:17 DL4647 Delta Air Lines Inc. Des Moines — Minneapolis 53m stop 15:10 — 17:48 DL2365 Delta Air Lines Inc. Minneapolis — Detroit 1h 41m stop 19:29 — 20:56 DL669 Delta Air Lines Inc. Detroit — San Diego	9h 51m including layover	Find flight from$109

Departuer	Arrival	Flight Details	Flight Time	Price
	stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on September 23, 2023

Flight Information

Below we will explain in detail what the flights cost on the destination from Des Moines to San Diego depends on and how to choose the most interesting flight option for you.

Distance between Des Moines and San Diego is 2295 miles. Time difference between the cities is 2h. Airplanes depart 06:00 to 21:31 from 1 Des Moines airport and arrive 06:00 to 21:31 to 11 San Diego airports. Average flight time is 10h 12m.

The fastest flight 5h
Average flight time 10h 12m
The earliest flight 06:00
The latest flight 21:31
Distance 1427 ml

What is the lowest airfare Des Moines to San Diego?

The cheapest plane ticket found by our users is $50. This airfare is for economy class on one-way AA2326 flight by American Airlines for August 26, 2020 which leaves Des Moines International Airport in Des Moines at 09:30 am and arrives at San Diego San Diego at 18:45.

Economy class

$50

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Business class

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First class

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Popular Airlines on the Route

The flight Des Moines — San Diego is served by 7 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by American Airlines - 49 departures per week at the price of from $ 50 . And the most expensive tickets are offered by Alaska Airlines airline - from $ 1052.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 120 flights with layovers on the route. The fastest connecting flight is AA2996 by American Airlines takes 5h and the cheapest is AA2326 by American Airlines for $50.

AA - American Airlines

from $50

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AS - Alaska Airlines

from $1052

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F9 - Frontier Airlines

from $69

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WN - Southwest Airlines

from $94

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DL - Delta Air Lines Inc.

from $102

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UA - United Airlines

from $50

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G4 - Allegiant Air

from $94

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Airports

You can fly from Des Moines to San Diego from 1 airports (Des Moines International Airport).

Des Moines airports

Des Moines International Airport-DSM

from $50
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San Diego airports

San Diego-SAN

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San Diego Regional-USA

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Gillespie Field-SEE

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Golden Triangle Reg.-GTR

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El Cajon-CJN

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Lowndes County-UBS

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Miramar NAS-NKX

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Montgomery Field-MYF

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North Island NAS-NZY

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Brown Field Municipal-SDM

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AFB-CBM

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Airplanes

There are flights to San Diego from Des Moines by 7 airlines that use 7 aircraft brands. They range from huge modern airplanes to small-sized.

Airbus A319

from $50

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Embraer 175 (winglets)

from $50

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Bombardier CRJ 900

from $51

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Embraer 175

from $51

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Bombardier CRJ 700

from $52

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Airbus A320

from $69

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Canadair Regional Jet 900

from $109

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Top Domestic Destinations from Des Moines

You may also consider searching for discounted plane tickets to some other popular places from Des Moines within United States.

Des Moines — Denver

from $54

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Des Moines — Philadelphia

from $71

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Des Moines — Colorado Springs

from $73

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Des Moines — San Antonio

from $61

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Des Moines — Orlando

from $74

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Des Moines — Chicago

from $72

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Des Moines — Indianapolis

from $62

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Des Moines — Boston

from $65

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Des Moines — San Diego

from $58

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Des Moines — El Paso

from $73

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Top International Destinations from Des Moines

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Des Moines — Guadalajara

from $71

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Des Moines — Cancun

from $77

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Des Moines — London

from $70

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All flights from Des Moines | All flights to San Diego

How to book a plane ticket yourself?

Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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