Cheap Flights from Des Moines, IA to San Diego, CA from $53

On Cheapflightsplus.com you will find 120 connecting flights from Des Moines to San Diego. You can compare airfare deals from 7 airlines and multiple travel sites from $53, book and save on cheap plane tickets and last minute offers. Also check out DSM-SAN flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Des Moines to San Diego Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $53 (one-way), $91 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Des Moines to San Diego. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
06:30 — 10:46
06:30 — 08:44 UA6115 United Airlines
Des Moines — Houston
51m stop
09:35 — 10:46 UA2358 United Airlines
Houston — San Diego
6h 16m
including layover
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from$54
06:59 — 13:24
06:59 — 10:25 AA4377 American Airlines
Des Moines — Charlotte
1h 15m stop
11:40 — 13:24 AA1676 American Airlines
Charlotte — San Diego
8h 25m
including layover
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from$55
07:00 — 11:28
07:00 — 08:15 UA5680 United Airlines
Des Moines — Chicago
1h stop
09:15 — 11:28 UA348 United Airlines
Chicago — San Diego
6h 28m
including layover
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from$54
07:53 — 12:47
07:53 — 08:41 UA771 United Airlines
Des Moines — Denver
2h 44m stop
11:25 — 12:47 UA1108 United Airlines
Denver — San Diego
6h 54m
including layover
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from$54
08:26 — 11:34
08:26 — 09:20 AA1795 American Airlines
Des Moines — Phoenix
59m stop
10:19 — 11:34 AA2671 American Airlines
Phoenix — San Diego
5h 8m
including layover
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from$56
08:37 — 17:09
08:37 — 10:05 UA3591 United Airlines
Des Moines — Chicago
4h 56m stop
15:01 — 17:09 NK563 Spirit Airlines
Chicago — San Diego
10h 32m
including layover
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from$89
11:58 — 20:10
11:58 — 15:20 AA5421 American Airlines
Des Moines — Charlotte
3h 5m stop
18:25 — 20:10 AA1740 American Airlines
Charlotte — San Diego
10h 12m
including layover
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from$55
12:30 — 16:05
12:30 — 13:25 WN1596 Southwest Airlines
Des Moines — Denver
1h 20m stop
14:45 — 16:05 WN407 Southwest Airlines
Denver — San Diego
5h 35m
including layover
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from$101
12:30 — 18:15
12:30 — 13:25 WN1596 Southwest Airlines
Des Moines — Denver
3h 30m stop
16:55 — 18:15 WN101 Southwest Airlines
Denver — San Diego
7h 45m
including layover
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from$102
15:09 — 22:40
15:09 — 16:29 UA4508 United Airlines
Des Moines — Chicago
3h 56m stop
20:25 — 22:40 UA308 United Airlines
Chicago — San Diego
9h 31m
including layover
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from$54
15:30 — 19:44
15:30 — 17:20 AA1536 American Airlines
Des Moines — Dallas
1h 25m stop
18:45 — 19:44 AA1243 American Airlines
Dallas — San Diego
6h 14m
including layover
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from$56
16:17 — 22:35
16:17 — 17:45 AA2968 American Airlines
Des Moines — Chicago
2h 35m stop
20:20 — 22:35 AA1457 American Airlines
Chicago — San Diego
8h 18m
including layover
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from$56
16:17 — 17:09
+1 day
16:17 — 17:45 AA2968 American Airlines
Des Moines — Chicago
21h 16m stop
15:01 — 17:09 NK563 Spirit Airlines
Chicago — San Diego
26h 52m
including layover
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from$89
17:30 — 21:34
17:30 — 19:27 AA5832 American Airlines
Des Moines — Dallas
1h 13m stop
20:40 — 21:34 AA2741 American Airlines
Dallas — San Diego
6h 4m
including layover
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from$57
17:36 — 20:59
17:36 — 18:40 UA5564 United Airlines
Des Moines — Denver
55m stop
19:35 — 20:59 UA540 United Airlines
Denver — San Diego
5h 23m
including layover
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from$54
18:10 — 23:41
18:10 — 19:05 F9155 Frontier Airlines
Des Moines — Denver
3h 15m stop
22:20 — 23:41 F9551 Frontier Airlines
Denver — San Diego
7h 31m
including layover
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from$74
21:31 — 10:34
+1 day
21:31 — 22:34 G42455 Allegiant Air
Des Moines — Las Vegas
10h 53m stop
09:27 — 10:34 NK429 Spirit Airlines
Las Vegas — San Diego
15h 3m
including layover
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from$101
09:30 — 18:45
09:30 — 11:21 AA2326 American Airlines
Des Moines — Dallas
2h 39m stop
14:00 — 14:24 AA526 American Airlines
Dallas — Phoenix
3h 12m stop
17:36 — 18:45 AA559 American Airlines
Phoenix — San Diego
11h 15m
including layover
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from$53
09:30 — 18:45
09:30 — 11:21 AA2326 American Airlines
Des Moines — Dallas
3h 18m stop
14:39 — 15:04 AA2259 American Airlines
Dallas — Phoenix
2h 32m stop
17:36 — 18:45 AA559 American Airlines
Phoenix — San Diego
11h 15m
including layover
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from$53
11:50 — 18:30
11:50 — 13:15 UA4417 United Airlines
Des Moines — Chicago
1h 12m stop
14:27 — 16:50 UA1969 United Airlines
Chicago — Los Angeles
50m stop
17:40 — 18:30 UA5247 United Airlines
Los Angeles — San Diego
8h 40m
including layover
Find flight
from$104
13:05 — 22:15
13:05 — 14:17 DL4647 Delta Air Lines Inc.
Des Moines — Minneapolis
2h 16m stop
16:33 — 20:00 DL1736 Delta Air Lines Inc.
Minneapolis — Atlanta
59m stop
20:59 — 22:15 DL1200 Delta Air Lines Inc.
Atlanta — San Diego
11h 10m
including layover
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from$110
13:05 — 20:56
13:05 — 14:17 DL4647 Delta Air Lines Inc.
Des Moines — Minneapolis
53m stop
15:10 — 17:48 DL2365 Delta Air Lines Inc.
Minneapolis — Detroit
1h 41m stop
19:29 — 20:56 DL669 Delta Air Lines Inc.
Detroit — San Diego
9h 51m
including layover
Find flight
from$117
*Departure and arrival times - local. Updated on July 21, 2024

Flight Information

Below we will explain in detail what the flights cost on the destination from Des Moines to San Diego depends on and how to choose the most interesting flight option for you.

Distance between Des Moines and San Diego is 2295 miles. Time difference between the cities is 2h. Airplanes depart 06:00 to 21:31 from 1 Des Moines airport and arrive 06:00 to 21:31 to 11 San Diego airports. Average flight time is 10h 12m.

  • The fastest flight 5h
  • Average flight time 10h 12m
  • The earliest flight 06:00
  • The latest flight 21:31
  • Distance 1427 ml

What is the lowest airfare Des Moines to San Diego?

The cheapest plane ticket found by our users is $53. This airfare is for economy class on one-way AA2326 flight by American Airlines for August 26, 2020 which leaves Des Moines International Airport in Des Moines at 09:30 am and arrives at San Diego San Diego at 18:45.

Economy class
$53
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Business class
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First class
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Popular Airlines on the Route

The flight Des Moines — San Diego is served by 7 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by American Airlines - 49 departures per week at the price of from $ 53 . And the most expensive tickets are offered by Alaska Airlines airline - from $ 1135.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 120 flights with layovers on the route. The fastest connecting flight is AA2996 by American Airlines takes 5h and the cheapest is AA2326 by American Airlines for $53.

  • AA - American Airlines
    from $53
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  • AS - Alaska Airlines
    from $1135
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  • F9 - Frontier Airlines
    from $74
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  • WN - Southwest Airlines
    from $101
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  • DL - Delta Air Lines Inc.
    from $110
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  • UA - United Airlines
    from $54
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  • G4 - Allegiant Air
    from $101
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See more connecting flights

Airports

You can fly from Des Moines to San Diego from 1 airports (Des Moines International Airport).

Des Moines airports

  • Des Moines International Airport-DSM
    from $53
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San Diego airports

  • San Diego-SAN
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  • San Diego Regional-USA
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  • Gillespie Field-SEE
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  • Golden Triangle Reg.-GTR
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  • El Cajon-CJN
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  • Lowndes County-UBS
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  • Miramar NAS-NKX
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  • Montgomery Field-MYF
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  • North Island NAS-NZY
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  • Brown Field Municipal-SDM
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  • AFB-CBM
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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