Cheap Flights from Des Moines, IA to San Diego, CA from $73

One way Round trip

Adults

Children under 12

Infants under 2 without place

Economy

Business

First

done

Return flight: San Diego – Des Moines

Page navigation

Price Calendar Cheap Flights Flights Schedule

On Cheapflightsplus.com you will find 41 connecting flights from Des Moines to San Diego. You can compare airfare deals from 3 airlines and multiple travel sites from $73, book and save on cheap plane tickets and last minute offers. Also check out DSM-SAN flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Des Moines to San Diego Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $73 (one-way), $125 (round-trip).

Direct flights

Check to choose departure date Check to choose departure date

Check prices for return flight

Find flights

Best Flights from Des Moines to San Diego Today

Take a look at the list of non stop flights and flights with layovers from Des Moines to San Diego with the lowest price of $73. Take a look at the list of flights with layovers from Des Moines to San Diego from $73. There’re no direct flights. The fastest connecting flight – 5h 36m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $73 Find flight	21:21 Des Moines Des Moines International Airport	06:24+1 день San Diego San Diego	11h 3m layover 6h 41m - Denver	Frontier Airlines	F91677 F92817
from $245 Find flight	14:37 Des Moines Des Moines International Airport	20:05 San Diego San Diego	7h 28m layover 2h 56m - Phoenix	Alaska Airlines	AS4135 AS4295
from $248 Find flight	13:49 Des Moines Des Moines International Airport	17:25 San Diego San Diego	5h 36m layover 0h 56m - Denver	United Airlines	UA5835 UA1281
from $248 Find flight	05:45 Des Moines Des Moines International Airport	09:29 San Diego San Diego	5h 44m layover 0h 56m - Denver	United Airlines	UA4700 UA2309
from $248 Find flight	15:05 Des Moines Des Moines International Airport	22:00 San Diego San Diego	8h 55m layover 2h 32m - Houston	United Airlines	UA6033 UA1511
from $248 Find flight	15:27 Des Moines Des Moines International Airport	22:30 San Diego San Diego	9h 3m layover 2h 50m - Chicago	United Airlines	UA3457 UA1773
from $251 Find flight	17:13 Des Moines Des Moines International Airport	22:40 San Diego San Diego	7h 27m layover 2h 45m - Denver	United Airlines	UA1781 UA486
from $251 Find flight	11:29 Des Moines Des Moines International Airport	19:00 San Diego San Diego	9h 31m layover 3h 23m - Chicago	United Airlines	UA1373 UA2184
from $303 Find flight	15:01 Des Moines Des Moines International Airport	20:18 San Diego San Diego	7h 17m layover 1h 0m - Houston	United Airlines	UA6033 UA1373
from $303 Find flight	15:01 Des Moines Des Moines International Airport	21:33 San Diego San Diego	8h 32m layover 2h 15m - Houston	United Airlines	UA6033 UA2674
from $253 Find flight	05:45 Des Moines Des Moines International Airport	14:49 San Diego San Diego	11h 4m layover 3h 13m - Denver 1h 6m - San Francisco	United Airlines	UA4700 UA2041 UA2041
from $253 Find flight	08:00 Des Moines Des Moines International Airport	18:34 San Diego San Diego	12h 34m layover 1h 40m - Houston 2h 5m - San Francisco	United Airlines	UA735 UA1057 UA1057
from $256 Find flight	12:15 Des Moines Des Moines International Airport	23:59 San Diego San Diego	13h 44m layover 2h 17m - Chicago 2h 45m - Portland	Alaska Airlines	AS4423 AS413 AS1162
from $277 Find flight	05:55 Des Moines Des Moines International Airport	16:34 San Diego San Diego	12h 39m layover 2h 34m - Chicago 1h 6m - Seattle	Alaska Airlines	AS6892 AS462 AS1454
from $277 Find flight	05:55 Des Moines Des Moines International Airport	19:10 San Diego San Diego	15h 15m layover 2h 34m - Chicago 3h 41m - Seattle	Alaska Airlines	AS6892 AS462 AS1142
from $277 Find flight	05:00 Des Moines Des Moines International Airport	19:10 San Diego San Diego	16h 10m layover 2h 44m - Dallas 3h 55m - Seattle	Alaska Airlines	AS4133 AS573 AS1142

Show all tickets

*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on January 14, 2025

Flight Schedule Des Moines (Iowa) to San Diego (California)

Full flight schedule will help you in detecting at what time planes fly from Des Moines to San Diego. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
05:45 — 09:29	05:45 — 07:02 UA4700 United Airlines Des Moines — Denver 56m stop 08:00 — 09:30 UA2309 United Airlines Denver — San Diego	5h 44m including layover	Find flight from$248
08:00 — 13:53	08:00 — 10:36 UA1982 United Airlines Des Moines — Houston 1h 34m stop 12:10 — 13:53 UA2486 United Airlines Houston — San Diego	7h 53m including layover	Find flight from$360
09:10 — 22:40	09:10 — 10:17 UA581 United Airlines Des Moines — Denver 10h 48m stop 21:05 — 22:40 UA486 United Airlines Denver — San Diego	15h 30m including layover	Find flight from$369
09:10 — 13:11	09:10 — 10:17 UA581 United Airlines Des Moines — Denver 1h 17m stop 11:34 — 13:11 UA366 United Airlines Denver — San Diego	6h 1m including layover	Find flight from$395
11:29 — 19:00	11:29 — 12:57 UA1373 United Airlines Des Moines — Chicago 3h 23m stop 16:20 — 19:00 UA2184 United Airlines Chicago — San Diego	9h 31m including layover	Find flight from$251
13:47 — 22:40	13:47 — 15:00 UA5835 United Airlines Des Moines — Denver 6h 5m stop 21:05 — 22:40 UA486 United Airlines Denver — San Diego	10h 53m including layover	Find flight from$338
13:49 — 17:25	13:45 — 14:51 UA5835 United Airlines Des Moines — Denver 56m stop 16:01 — 17:29 UA1281 United Airlines Denver — San Diego	5h 36m including layover	Find flight from$248
14:37 — 20:05	14:37 — 16:52 AS4135 Alaska Airlines Des Moines — Phoenix 2h 56m stop 19:48 — 20:05 AS4295 Alaska Airlines Phoenix — San Diego	7h 28m including layover	Find flight from$245
15:05 — 22:00	15:05 — 17:48 UA6033 United Airlines Des Moines — Houston 2h 32m stop 20:20 — 22:00 UA1511 United Airlines Houston — San Diego	8h 55m including layover	Find flight from$248
15:27 — 22:30	15:27 — 17:05 UA3457 United Airlines Des Moines — Chicago 2h 50m stop 19:55 — 22:30 UA1773 United Airlines Chicago — San Diego	9h 3m including layover	Find flight from$248
17:13 — 22:40	17:13 — 18:20 UA1781 United Airlines Des Moines — Denver 2h 45m stop 21:05 — 22:40 UA486 United Airlines Denver — San Diego	7h 27m including layover	Find flight from$251
21:21 — 06:24 +1 day	18:51 — 19:57 F91677 Frontier Airlines Des Moines — Denver 6h 41m stop 05:35 — 07:05 F92817 Frontier Airlines Denver — San Diego	11h 3m including layover	Find flight from$73
05:45 — 14:49	05:45 — 07:02 UA4700 United Airlines Des Moines — Denver 3h 13m stop 10:15 — 12:04 UA2041 United Airlines Denver — San Francisco 1h 6m stop 13:10 — 14:49 UA2041 United Airlines San Francisco — San Diego	11h 4m including layover	Find flight from$253
08:00 — 18:34	08:00 — 10:37 UA735 United Airlines Des Moines — Houston 1h 40m stop 12:17 — 14:50 UA1057 United Airlines Houston — San Francisco 2h 5m stop 16:55 — 18:34 UA1057 United Airlines San Francisco — San Diego	12h 34m including layover	Find flight from$253
11:29 — 20:18	11:29 — 12:57 UA1373 United Airlines Des Moines — Chicago 1h 3m stop 14:00 — 17:03 UA1373 United Airlines Chicago — Houston 1h 32m stop 18:35 — 20:18 UA1373 United Airlines Houston — San Diego	10h 49m including layover	Find flight from$308
12:15 — 23:59	12:15 — 13:48 AS4423 Alaska Airlines Des Moines — Chicago 2h 17m stop 16:05 — 18:44 AS413 Alaska Airlines Chicago — Portland 2h 45m stop 21:29 — 23:59 AS1162 Alaska Airlines Portland — San Diego	13h 44m including layover	Find flight from$256
12:57 — 23:16	12:57 — 16:26 AS4132 Alaska Airlines Des Moines — Washington D.C. 49m stop 17:15 — 20:46 AS7 Alaska Airlines Washington D.C. — San Francisco 54m stop 21:40 — 23:16 AS3457 Alaska Airlines San Francisco — San Diego	12h 19m including layover	Find flight from$466

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on January 14, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Des Moines to San Diego depends on and how to choose the most interesting flight option for you.

Distance between Des Moines and San Diego is 2295 miles. Time difference between the cities is 2h. Airplanes depart 05:00 to 21:21 from 1 Des Moines airport and arrive 05:00 to 21:21 to 11 San Diego airports. Average flight time is 12h 4m.

The fastest flight 5h 36m
Average flight time 12h 4m
The earliest flight 05:00
The latest flight 21:21
Distance 1427 ml

The cheapest months to travel to San Diego are november (from 53 $), february (from 73 $), january (from 245 $).

The most expensive months are december (from 245 $), january (from 245 $), february (from 73 $).

What is the lowest airfare Des Moines to San Diego?

The cheapest plane ticket found by our users is $73. This airfare is for economy class on one-way F91677 flight by Frontier Airlines for February 21, 2025 which leaves Des Moines International Airport in Des Moines at 21:21 am and arrives at San Diego San Diego at 06:24.

Economy class

$73

Find

Business class

Find

First class

Find

Popular Airlines on the Route

The flight Des Moines — San Diego is served by 3 regular airlines and 1 low-cost airline. Most of the flights on this route are operated by Alaska Airlines - 12 departures per week at the price of from $ 245 . And the most expensive tickets are offered by Alaska Airlines airline - from $ 638.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 41 flights with layovers on the route. The fastest connecting flight is UA5835 by United Airlines takes 5h 36m and the cheapest is F91677 by Frontier Airlines for $73.

AS - Alaska Airlines

from $245

Find
F9 - Frontier Airlines

from $73

Find
UA - United Airlines

from $248

Find

See more connecting flights

Airports

You can fly from Des Moines to San Diego from 1 airports (Des Moines International Airport).

Des Moines airports

Des Moines International Airport-DSM

from $73
Find

San Diego airports

San Diego-SAN

Find
San Diego Regional-USA

Find
Gillespie Field-SEE

Find
Golden Triangle Reg.-GTR

Find
El Cajon-CJN

Find
Lowndes County-UBS

Find
Miramar NAS-NKX

Find
Montgomery Field-MYF

Find
North Island NAS-NZY

Find
Brown Field Municipal-SDM

Find
AFB-CBM

Find

Airplanes

There are flights to San Diego from Des Moines by 3 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Des Moines

You may also consider searching for discounted plane tickets to some other popular places from Des Moines within United States.

Des Moines — Denver

from $54

Find
Des Moines — Philadelphia

from $71

Find
Des Moines — Colorado Springs

from $73

Find
Des Moines — San Antonio

from $61

Find
Des Moines — Orlando

from $74

Find
Des Moines — Chicago

from $72

Find
Des Moines — Indianapolis

from $62

Find
Des Moines — Boston

from $65

Find
Des Moines — San Diego

from $58

Find
Des Moines — El Paso

from $73

Find

Top International Destinations from Des Moines

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Des Moines — Guadalajara

from $71

Find
Des Moines — Cancun

from $77

Find
Des Moines — London

from $70

Find

How to book a plane ticket yourself?

Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
To find a plane ticket, please select dates.