Cheap Flights from Des Moines, IA to San Diego, CA from $62
On Cheapflightsplus.com you will find 2 direct and 192 connecting flights from Des Moines to San Diego. You can compare airfare deals from 4 airlines and multiple travel sites from $62, book and save on cheap plane tickets and last minute offers. Also check out DSM-SAN flight schedule to find best flight time, convenient departure and arrival airports.
Flight Information
Below we will explain in detail what the flights cost on the destination from Des Moines to San Diego depends on and how to choose the most interesting flight option for you.
Distance between Des Moines and San Diego is 2295 miles. Time difference between the cities is 2h. Airplanes depart 05:00 to 22:31 from 1 Des Moines airport and arrive 05:00 to 22:31 to 11 San Diego airports. Average flight time is 3h 34m.
- The fastest flight 3h 31m
- Average flight time 3h 34m
- The earliest flight 05:00
- The latest flight 22:31
- Distance 1427 ml
Best Flights from Des Moines to San Diego Today
Price | Departure | Arrival | Flight Duration | Airline | Flight |
---|---|---|---|---|---|
from $62 | 14:39 Des Moines Des Moines International Airport | 16:10 San Diego San Diego | 3h 31m | Allegiant Air | G42074 |
from $72 | 14:54 Des Moines Des Moines International Airport | 16:30 San Diego San Diego | 3h 36m | Allegiant Air | G4474 |
from $97 | 22:31 Des Moines Des Moines International Airport | 07:13+1 день San Diego San Diego | 10h 42m layover 6h 23m - Las Vegas | Allegiant Air | G415 NK2502 |
from $114 | 13:15 Des Moines Des Moines International Airport | 17:55 San Diego San Diego | 6h 40m layover 2h 17m - Las Vegas | Allegiant Air | G449 NK1150 |
The cheapest months to travel to San Diego are july (from 62 $), august (from 62 $), september (from 210 $).
The most expensive months are february (from 375 $), november (from 367 $), september (from 210 $).
What is the lowest airfare Des Moines to San Diego?
The cheapest plane ticket found by our users is $62. This airfare is for economy class on one-way G42074 flight by Allegiant Air for July 4, 2025 which leaves Des Moines International Airport in Des Moines at 14:39 am and arrives at San Diego San Diego at 16:10.
Flight Schedule Des Moines (Iowa) to San Diego (California)
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Popular Airlines on the Route
The flight Des Moines — San Diego is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 11 departures per week at the price of from $ 190 . And the most expensive tickets are offered by United Airlines airline - from $ 913.
Direct flights
There are 2 nonstop flights on the route. The fastest direct flight is G42074 by Allegiant Air takes 3h 31m and the cheapest is G42074 by Allegiant Air for $62.
- G4 - Allegiant Airfrom $62Find
Connecting Flights
There are 192 flights with layovers on the route. The fastest connecting flight is UA4790 by United Airlines takes 5h 9m and the cheapest is G42074 by Allegiant Air for $97.
- AS - Alaska Airlinesfrom $190Find
- F9 - Frontier Airlinesfrom $117Find
- UA - United Airlinesfrom $189Find
- G4 - Allegiant Airfrom $97Find
Airports
You can fly from Des Moines to San Diego from 1 airports (Des Moines International Airport).
Des Moines airports
- Des Moines International Airport-DSMfrom $62Find
San Diego airports
- San Diego-SANFind
- San Diego Regional-USAFind
- Gillespie Field-SEEFind
- Golden Triangle Reg.-GTRFind
- El Cajon-CJNFind
- Lowndes County-UBSFind
- Miramar NAS-NKXFind
- Montgomery Field-MYFFind
- North Island NAS-NZYFind
- Brown Field Municipal-SDMFind
- AFB-CBMFind
Airplanes
There are flights to San Diego from Des Moines by 4 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Des Moines
You may also consider searching for discounted plane tickets to some other popular places from Des Moines within United States.
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Top International Destinations from Des Moines
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
- from $77Find
- from $70Find
How to book a plane ticket yourself?

- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
- Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
- Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
- Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
- That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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