Cheap Flights from Des Moines, IA to San Diego, CA from $76

On Cheapflightsplus.com you will find 89 connecting flights from Des Moines to San Diego. You can compare airfare deals from 4 airlines and multiple travel sites from $76, book and save on cheap plane tickets and last minute offers. Also check out DSM-SAN flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Des Moines to San Diego Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $76 (one-way), $130 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Des Moines to San Diego. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
05:00 — 11:34
05:00 — 07:35 AS6332 Alaska Airlines
Des Moines — Phoenix
3h 38m stop
11:13 — 11:34 AS4295 Alaska Airlines
Phoenix — San Diego
8h 34m
including layover
Find flight
from$258
05:45 — 09:29
05:45 — 07:02 UA4700 United Airlines
Des Moines — Denver
56m stop
08:00 — 09:30 UA2309 United Airlines
Denver — San Diego
5h 44m
including layover
Find flight
from$259
06:00 — 09:28
06:00 — 07:04 UA497 United Airlines
Des Moines — Denver
56m stop
08:05 — 09:33 UA2309 United Airlines
Denver — San Diego
5h 28m
including layover
Find flight
from$257
06:00 — 11:18
06:00 — 07:04 UA497 United Airlines
Des Moines — Denver
2h 46m stop
10:20 — 11:48 UA1842 United Airlines
Denver — San Diego
7h 18m
including layover
Find flight
from$257
09:00 — 12:53
09:02 — 10:17 UA581 United Airlines
Des Moines — Denver
1h 10m stop
11:40 — 13:08 UA2381 United Airlines
Denver — San Diego
5h 53m
including layover
Find flight
from$257
09:00 — 11:18
+1 day
09:02 — 10:17 UA581 United Airlines
Des Moines — Denver
23h 35m stop
10:15 — 11:43 UA1842 United Airlines
Denver — San Diego
28h 18m
including layover
Find flight
from$314
11:29 — 18:51
11:29 — 13:00 UA3417 United Airlines
Des Moines — Chicago
3h 20m stop
16:20 — 18:51 UA2080 United Airlines
Chicago — San Diego
9h 22m
including layover
Find flight
from$257
11:29 — 19:00
11:29 — 12:57 UA1373 United Airlines
Des Moines — Chicago
3h 23m stop
16:20 — 19:00 UA2184 United Airlines
Chicago — San Diego
9h 31m
including layover
Find flight
from$262
13:45 — 20:53
13:45 — 14:51 UA5835 United Airlines
Des Moines — Denver
4h 34m stop
19:25 — 20:53 UA540 United Airlines
Denver — San Diego
9h 8m
including layover
Find flight
from$310
13:49 — 17:25
13:45 — 14:51 UA5835 United Airlines
Des Moines — Denver
56m stop
16:01 — 17:29 UA1281 United Airlines
Denver — San Diego
5h 36m
including layover
Find flight
from$257
14:37 — 20:05
14:37 — 16:52 AS4135 Alaska Airlines
Des Moines — Phoenix
2h 56m stop
19:48 — 20:05 AS4295 Alaska Airlines
Phoenix — San Diego
7h 28m
including layover
Find flight
from$257
15:23 — 22:22
15:23 — 16:51 UA1568 United Airlines
Des Moines — Chicago
2h 59m stop
19:50 — 22:22 UA2735 United Airlines
Chicago — San Diego
8h 59m
including layover
Find flight
from$257
15:35 — 23:52
15:35 — 17:03 G4451 Allegiant Air
Des Moines — Las Vegas
5h 38m stop
22:41 — 23:52 NK191 Spirit Airlines
Las Vegas — San Diego
10h 17m
including layover
Find flight
from$111
17:07 — 23:49
18:51 — 19:57 F91677 Frontier Airlines
Des Moines — Denver
3h 57m stop
19:56 — 21:25 F94989 Frontier Airlines
Denver — San Diego
8h 42m
including layover
Find flight
from$142
17:13 — 22:40
17:13 — 18:20 UA1781 United Airlines
Des Moines — Denver
2h 45m stop
21:05 — 22:40 UA486 United Airlines
Denver — San Diego
7h 27m
including layover
Find flight
from$262
21:21 — 06:24
+1 day
18:51 — 19:57 F91677 Frontier Airlines
Des Moines — Denver
6h 41m stop
05:35 — 07:05 F92817 Frontier Airlines
Denver — San Diego
11h 3m
including layover
Find flight
from$76
07:00 — 22:17
07:00 — 08:45 G4457 Allegiant Air
Des Moines — Santa Ana
5h 3m stop
13:48 — 15:00 NK874 Spirit Airlines
Santa Ana — Las Vegas
6h 5m stop
21:05 — 22:17 NK1496 Spirit Airlines
Las Vegas — San Diego
17h 17m
including layover
Find flight
from$155
07:00 — 18:15
07:00 — 08:45 G4457 Allegiant Air
Des Moines — Santa Ana
5h 3m stop
13:48 — 15:00 NK874 Spirit Airlines
Santa Ana — Las Vegas
1h 57m stop
16:57 — 18:15 NK2907 Spirit Airlines
Las Vegas — San Diego
13h 15m
including layover
Find flight
from$159
08:00 — 23:52
08:00 — 12:22 G4436 Allegiant Air
Des Moines — Miami
3h 34m stop
15:56 — 18:32 NK201 Spirit Airlines
Miami — Las Vegas
4h 9m stop
22:41 — 23:52 NK191 Spirit Airlines
Las Vegas — San Diego
17h 52m
including layover
Find flight
from$210
08:30 — 22:17
08:30 — 10:48 G42056 Allegiant Air
Des Moines — Austin
4h 1m stop
14:49 — 15:54 NK869 Spirit Airlines
Austin — Las Vegas
5h 11m stop
21:05 — 22:17 NK1496 Spirit Airlines
Las Vegas — San Diego
15h 47m
including layover
Find flight
from$248
12:15 — 23:59
12:15 — 13:43 AS6532 Alaska Airlines
Des Moines — Chicago
3h 45m stop
17:28 — 20:11 AS353 Alaska Airlines
Chicago — Seattle
1h 5m stop
21:16 — 23:59 AS1164 Alaska Airlines
Seattle — San Diego
13h 44m
including layover
Find flight
from$262
14:29 — 08:13
+1 day
14:29 — 16:38 G42062 Allegiant Air
Des Moines — Phoenix
5h 33m stop
22:11 — 22:22 NK536 Spirit Airlines
Phoenix — Las Vegas
8h 38m stop
07:00 — 08:13 NK375 Spirit Airlines
Las Vegas — San Diego
19h 44m
including layover
Find flight
from$185
*Departure and arrival times - local. Updated on November 14, 2024

Flight Information

Below we will explain in detail what the flights cost on the destination from Des Moines to San Diego depends on and how to choose the most interesting flight option for you.

Distance between Des Moines and San Diego is 2295 miles. Time difference between the cities is 2h. Airplanes depart 05:00 to 21:21 from 1 Des Moines airport and arrive 05:00 to 21:21 to 11 San Diego airports. Average flight time is 12h 19m.

  • The fastest flight 5h 25m
  • Average flight time 12h 19m
  • The earliest flight 05:00
  • The latest flight 21:21
  • Distance 1427 ml

The cheapest months to travel to San Diego are november (from 56 $), february (from 76 $), january (from 111 $).

The most expensive months are december (from 142 $), january (from 111 $), february (from 76 $).

What is the lowest airfare Des Moines to San Diego?

The cheapest plane ticket found by our users is $76. This airfare is for economy class on one-way F91677 flight by Frontier Airlines for February 21, 2025 which leaves Des Moines International Airport in Des Moines at 21:21 am and arrives at San Diego San Diego at 06:24.

Economy class
$76
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Business class
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First class
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Popular Airlines on the Route

The flight Des Moines — San Diego is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 22 departures per week at the price of from $ 257 . And the most expensive tickets are offered by Alaska Airlines airline - from $ 667.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 89 flights with layovers on the route. The fastest connecting flight is UA1781 by United Airlines takes 5h 25m and the cheapest is F91677 by Frontier Airlines for $76.

  • AS - Alaska Airlines
    from $257
    Find
  • F9 - Frontier Airlines
    from $76
    Find
  • UA - United Airlines
    from $257
    Find
  • G4 - Allegiant Air
    from $111
    Find
See more connecting flights

Airports

You can fly from Des Moines to San Diego from 1 airports (Des Moines International Airport).

Des Moines airports

  • Des Moines International Airport-DSM
    from $76
    Find

San Diego airports

  • San Diego-SAN
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  • San Diego Regional-USA
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  • Gillespie Field-SEE
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  • Golden Triangle Reg.-GTR
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  • El Cajon-CJN
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  • Lowndes County-UBS
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  • Miramar NAS-NKX
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  • Montgomery Field-MYF
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  • North Island NAS-NZY
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  • Brown Field Municipal-SDM
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  • AFB-CBM
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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