Cheap Flights from Des Moines, IA to Chicago, IL from $56

Return flight: Chicago – Des Moines

On Cheapflightsplus.com you will find 8 direct and 142 connecting flights from Des Moines to Chicago. You can compare airfare deals from 6 airlines and multiple travel sites from $56, book and save on cheap plane tickets and last minute offers. Also check out DSM-CHI flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Des Moines to Chicago Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $56 (one-way), $96 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Des Moines to Chicago. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
06:17 — 07:45
06:17 — 07:45 AA3252 American Airlines
Des Moines — Chicago
1h 28m
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from$57
07:00 — 08:15
07:00 — 08:15 UA5680 United Airlines
Des Moines — Chicago
1h 15m
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from$65
08:37 — 10:05
08:37 — 10:05 UA3591 United Airlines
Des Moines — Chicago
1h 28m
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from$65
11:50 — 13:15
11:50 — 13:15 UA4417 United Airlines
Des Moines — Chicago
1h 25m
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from$251
11:50 — 13:15
11:50 — 13:15 UA5802 United Airlines
Des Moines — Chicago
1h 25m
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from$297
12:51 — 14:19
12:51 — 14:19 AA3275 American Airlines
Des Moines — Chicago
1h 28m
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from$57
15:09 — 16:29
15:09 — 16:29 UA4508 United Airlines
Des Moines — Chicago
1h 20m
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from$65
16:17 — 17:45
16:17 — 17:45 AA2968 American Airlines
Des Moines — Chicago
1h 28m
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from$302
06:59 — 12:13
06:59 — 10:25 AA4377 American Airlines
Des Moines — Charlotte
45m stop
11:10 — 12:13 AA2408 American Airlines
Charlotte — Chicago
5h 14m
including layover
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from$56
06:59 — 14:14
06:59 — 10:25 AA4377 American Airlines
Des Moines — Charlotte
2h 41m stop
13:06 — 14:14 AA1650 American Airlines
Charlotte — Chicago
7h 15m
including layover
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from$56
07:00 — 10:05
07:00 — 08:00 WN374 Southwest Airlines
Des Moines — Lake Saint Louis
55m stop
08:55 — 10:05 WN431 Southwest Airlines
Lake Saint Louis — Chicago
3h 5m
including layover
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from$97
09:30 — 15:45
09:30 — 11:21 AA2326 American Airlines
Des Moines — Dallas
1h 53m stop
13:14 — 15:45 AA2429 American Airlines
Dallas — Chicago
6h 15m
including layover
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from$57
11:08 — 16:45
11:08 — 12:13 DL4675 Delta Air Lines Inc.
Des Moines — Minneapolis
3h 3m stop
15:16 — 16:45 DL357 Delta Air Lines Inc.
Minneapolis — Chicago
5h 37m
including layover
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from$84
11:53 — 19:16
11:53 — 15:21 AA5421 American Airlines
Des Moines — Charlotte
2h 39m stop
18:00 — 19:16 AA2488 American Airlines
Charlotte — Chicago
7h 23m
including layover
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from$72
12:30 — 19:50
12:30 — 13:25 WN1596 Southwest Airlines
Des Moines — Denver
3h 10m stop
16:35 — 19:50 WN1555 Southwest Airlines
Denver — Chicago
7h 20m
including layover
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from$117
13:05 — 16:45
13:05 — 14:17 DL4647 Delta Air Lines Inc.
Des Moines — Minneapolis
59m stop
15:16 — 16:45 DL357 Delta Air Lines Inc.
Minneapolis — Chicago
3h 40m
including layover
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from$88
16:02 — 08:05
+1 day
16:02 — 17:31 G42453 Allegiant Air
Des Moines — Nashville
12h 44m stop
06:15 — 08:05 UA5741 United Airlines
Nashville — Chicago
16h 3m
including layover
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from$122
17:30 — 22:54
17:30 — 19:27 AA5832 American Airlines
Des Moines — Dallas
1h 3m stop
20:30 — 22:54 AA1294 American Airlines
Dallas — Chicago
5h 24m
including layover
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from$57
09:30 — 22:18
09:30 — 11:21 AA2326 American Airlines
Des Moines — Dallas
1h 9m stop
12:30 — 16:32 AA2823 American Airlines
Dallas — Miami
3h 28m stop
20:00 — 22:18 AA2457 American Airlines
Miami — Chicago
12h 48m
including layover
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from$131
15:24 — 06:13
+1 day
15:24 — 18:50 AA4670 American Airlines
Des Moines — Charlotte
1h 20m stop
20:10 — 21:44 AA624 American Airlines
Charlotte — Las Vegas
2h 55m stop
00:39 — 06:13 F91418 Frontier Airlines
Las Vegas — Chicago
14h 49m
including layover
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from$103
16:02 — 20:10
+1 day
16:02 — 17:31 G42453 Allegiant Air
Des Moines — Nashville
16h 59m stop
10:30 — 13:38 NK1169 Spirit Airlines
Nashville — Newark
4h 57m stop
18:35 — 20:10 UA1601 United Airlines
Newark — Chicago
28h 8m
including layover
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from$109
17:59 — 12:55
+1 day
17:59 — 18:54 F9155 Frontier Airlines
Des Moines — Denver
5h 56m stop
00:50 — 06:20 F9290 Frontier Airlines
Denver — Tampa
4h 40m stop
11:00 — 12:55 NK728 Spirit Airlines
Tampa — Chicago
18h 56m
including layover
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from$57
18:10 — 12:54
+1 day
18:10 — 19:05 F9155 Frontier Airlines
Des Moines — Denver
5h 39m stop
00:44 — 05:41 F9418 Frontier Airlines
Denver — Atlanta
5h 49m stop
11:30 — 12:54 UA717 United Airlines
Atlanta — Chicago
18h 44m
including layover
Find flight
from$76
18:10 — 08:45
+2 days
18:10 — 19:05 F9155 Frontier Airlines
Des Moines — Denver
5h 20m stop
00:25 — 06:08 F9486 Frontier Airlines
Denver — Fort Myers
24h 52m stop
07:00 — 08:45 WN293 Southwest Airlines
Fort Myers — Chicago
38h 35m
including layover
Find flight
from$83
19:25 — 22:00
+1 day
19:25 — 20:20 F9155 Frontier Airlines
Des Moines — Denver
14h 39m stop
10:59 — 13:54 NK1316 Spirit Airlines
Denver — Minneapolis
6h 31m stop
20:25 — 22:00 WN462 Southwest Airlines
Minneapolis — Chicago
26h 35m
including layover
Find flight
from$167
20:02 — 13:01
+2 days
20:02 — 21:05 G42455 Allegiant Air
Des Moines — Las Vegas
19h 35m stop
16:40 — 19:41 NK799 Spirit Airlines
Las Vegas — Denver
13h 44m stop
09:25 — 13:01 F9412 Frontier Airlines
Denver — Chicago
40h 59m
including layover
Find flight
from$136
20:02 — 09:20
+2 days
20:02 — 21:05 G42455 Allegiant Air
Des Moines — Las Vegas
19h 35m stop
16:40 — 19:41 NK799 Spirit Airlines
Las Vegas — Denver
10h 12m stop
05:53 — 09:20 AA2606 American Airlines
Denver — Chicago
37h 18m
including layover
Find flight
from$147
*Departure and arrival times - local. Updated on April 23, 2024

Flight Information

Below we will explain in detail what the flights cost on the destination from Des Moines to Chicago depends on and how to choose the most interesting flight option for you.

Distance between Des Moines and Chicago is 501 miles. Time difference between the cities is 0h. Airplanes depart 06:00 to 20:02 from 1 Des Moines airport and arrive 06:00 to 20:02 to 7 Chicago airports. Average flight time is 1h 27m.

  • The fastest flight 1h 15m
  • Average flight time 1h 27m
  • The earliest flight 06:00
  • The latest flight 20:02
  • Distance 312 ml

What is the lowest airfare Des Moines to Chicago?

The cheapest plane ticket found by our users is $56. This airfare is for economy class on one-way AA4377 flight by American Airlines for August 24, 2020 which leaves Des Moines International Airport in Des Moines at 06:59 am and arrives at Chicago O'Hare International at 12:13.

Economy class
$56
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Business class
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First class
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Popular Airlines on the Route

The flight Des Moines — Chicago is served by 6 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by American Airlines - 49 departures per week at the price of from $ 56 . And the most expensive tickets are offered by Delta Air Lines Inc. airline - from $ 684.

Direct flights

There are 8 nonstop flights on the route. The fastest direct flight is UA5680 by United Airlines takes 1h 15m and the cheapest is AA4377 by American Airlines for $57.

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Connecting Flights

There are 142 flights with layovers on the route. The fastest connecting flight is WN374 by Southwest Airlines takes 3h 5m and the cheapest is AA4377 by American Airlines for $56.

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Airports

You can fly from Des Moines to Chicago from 1 airports (Des Moines International Airport).

Des Moines airports

  • Des Moines International Airport-DSM
    from $56
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Chicago airports

  • O'Hare International-ORD
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  • Midway-MDW
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  • Dupage County-DPA
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  • Chicago FSS-CHI
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  • Merrill C Meigs (closed)-CGX
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  • Pal-Waukee-PWK
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  • Chicago NAS-NOH
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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