Cheap Flights from Des Moines, IA to San Antonio, TX from $67
On Cheapflightsplus.com you will find 75 connecting flights from Des Moines to San Antonio. You can compare airfare deals from 3 airlines and multiple travel sites from $67, book and save on cheap plane tickets and last minute offers. Also check out DSM-SAT flight schedule to find best flight time, convenient departure and arrival airports.
Find One-Way and Round-Trip Des Moines to San Antonio Flight Deals
Best Flights from Des Moines to San Antonio Today
Price | Departure | Arrival | Flight Duration | Airline | Flight |
---|---|---|---|---|---|
from $67 | 21:21 Des Moines Des Moines International Airport | 08:19+1 день San Antonio San Antonio | 10h 58m layover 6h 46m - Denver | Frontier Airlines | F91677 F92356 |
from $279 | 08:00 Des Moines Des Moines International Airport | 13:07 San Antonio San Antonio | 5h 7m layover 1h 26m - Houston | United Airlines | UA735 UA274 |
from $279 | 09:00 Des Moines Des Moines International Airport | 16:40 San Antonio San Antonio | 7h 40m layover 3h 16m - Denver | United Airlines | UA581 UA1022 |
from $280 | 15:00 Des Moines Des Moines International Airport | 21:18 San Antonio San Antonio | 6h 18m layover 2h 35m - Houston | United Airlines | UA6033 UA1338 |
from $280 | 13:45 Des Moines Des Moines International Airport | 20:55 San Antonio San Antonio | 7h 10m layover 2h 52m - Denver | United Airlines | UA5835 UA1762 |
from $282 | 15:05 Des Moines Des Moines International Airport | 21:18 San Antonio San Antonio | 6h 13m layover 2h 18m - Houston | United Airlines | UA6033 UA1589 |
from $282 | 05:45 Des Moines Des Moines International Airport | 13:10 San Antonio San Antonio | 7h 25m layover 2h 56m - Denver | United Airlines | UA4700 UA1131 |
from $282 | 15:27 Des Moines Des Moines International Airport | 23:15 San Antonio San Antonio | 7h 48m layover 2h 58m - Chicago | United Airlines | UA3457 UA1504 |
from $324 | 08:00 Des Moines Des Moines International Airport | 13:27 San Antonio San Antonio | 5h 27m layover 1h 39m - Houston | United Airlines | UA1982 UA2378 |
from $196 | 07:30 Des Moines Des Moines International Airport | 23:30 San Antonio San Antonio | 16h 0m layover 5h 4m - Newark 2h 17m - Orlando | Allegiant Air | G4431 NK1861 NK446 |
from $196 | 07:30 Des Moines Des Moines International Airport | 04:59+1 день San Antonio San Antonio | 21h 29m layover 5h 38m - Newark 5h 3m - Las Vegas | Allegiant Air | G4431 NK3733 NK1058 |
from $228 | 07:30 Des Moines Des Moines International Airport | 23:30 San Antonio San Antonio | 16h 0m layover 3h 15m - Newark 4h 10m - Orlando | Allegiant Air | G4431 NK922 NK446 |
from $281 | 14:40 Des Moines Des Moines International Airport | 04:59+1 день San Antonio San Antonio | 14h 19m layover 6h 0m - Phoenix 1h 34m - Las Vegas | Allegiant Air | G4474 NK876 NK1058 |
from $288 | 11:35 Des Moines Des Moines International Airport | 19:22 San Antonio San Antonio | 7h 47m layover 0h 52m - Chicago 1h 6m - Houston | United Airlines | UA2306 UA1373 UA1477 |
from $288 | 15:27 Des Moines Des Moines International Airport | 23:14 San Antonio San Antonio | 7h 47m layover 0h 45m - Chicago 1h 15m - Houston | United Airlines | UA3457 UA1568 UA6158 |
from $288 | 11:35 Des Moines Des Moines International Airport | 21:18 San Antonio San Antonio | 9h 43m layover 0h 52m - Chicago 3h 2m - Houston | United Airlines | UA2306 UA1373 UA1589 |
Flight Schedule Des Moines (Iowa) to San Antonio (Texas)
Departure | Arrival | Flight Details | Flight Duration | Price |
---|---|---|---|---|
05:45 — 13:10
|
05:45 — 07:02
UA4700
United Airlines
Des Moines — Denver
2h 56m stop
10:05 — 13:21
UA1131
United Airlines
Denver — San Antonio
|
7h 25m including layover |
Find flight
from$282 |
|
05:45 — 16:40
|
05:45 — 07:02
UA4700
United Airlines
Des Moines — Denver
6h 24m stop
13:26 — 16:40
UA1022
United Airlines
Denver — San Antonio
|
10h 55m including layover |
Find flight
from$552 |
|
06:00 — 13:07
|
06:00 — 07:04
UA497
United Airlines
Des Moines — Denver
2h 51m stop
09:55 — 13:07
UA1131
United Airlines
Denver — San Antonio
|
7h 7m including layover |
Find flight
from$317 |
|
06:00 — 23:38
|
06:00 — 07:04
UA497
United Airlines
Des Moines — Denver
13h 21m stop
20:25 — 23:38
UA2028
United Airlines
Denver — San Antonio
|
17h 38m including layover |
Find flight
from$347 |
|
08:00 — 13:07
|
08:00 — 10:33
UA735
United Airlines
Des Moines — Houston
1h 26m stop
11:59 — 13:07
UA274
United Airlines
Houston — San Antonio
|
5h 7m including layover |
Find flight
from$279 |
|
08:00 — 15:26
|
08:00 — 10:33
UA735
United Airlines
Des Moines — Houston
3h 47m stop
14:20 — 15:26
UA1264
United Airlines
Houston — San Antonio
|
7h 26m including layover |
Find flight
from$279 |
|
09:00 — 16:40
|
09:02 — 10:17
UA581
United Airlines
Des Moines — Denver
3h 16m stop
13:41 — 16:54
UA1022
United Airlines
Denver — San Antonio
|
7h 40m including layover |
Find flight
from$279 |
|
09:02 — 23:38
|
09:02 — 10:17
UA581
United Airlines
Des Moines — Denver
10h 8m stop
20:25 — 23:38
UA2028
United Airlines
Denver — San Antonio
|
14h 36m including layover |
Find flight
from$347 |
|
13:45 — 20:55
|
13:45 — 14:51
UA5835
United Airlines
Des Moines — Denver
2h 52m stop
17:43 — 20:55
UA1762
United Airlines
Denver — San Antonio
|
7h 10m including layover |
Find flight
from$280 |
|
13:45 — 20:37
|
13:45 — 14:51
UA5669
United Airlines
Des Moines — Denver
2h 34m stop
17:25 — 20:37
UA1762
United Airlines
Denver — San Antonio
|
6h 52m including layover |
Find flight
from$317 |
|
14:10 — 06:57
+1 day
|
14:10 — 18:11
F91868
Frontier Airlines
Des Moines — Orlando
10h 50m stop
05:01 — 06:57
F91653
Frontier Airlines
Orlando — San Antonio
|
16h 47m including layover |
Find flight
from$545 |
|
15:00 — 21:18
|
15:00 — 17:35
UA6033
United Airlines
Des Moines — Houston
2h 35m stop
20:10 — 21:18
UA1338
United Airlines
Houston — San Antonio
|
6h 18m including layover |
Find flight
from$280 |
|
15:05 — 21:18
|
15:05 — 17:48
UA6033
United Airlines
Des Moines — Houston
2h 18m stop
20:06 — 21:18
UA1589
United Airlines
Houston — San Antonio
|
6h 13m including layover |
Find flight
from$282 |
|
17:10 — 23:38
|
17:10 — 18:19
UA1781
United Airlines
Des Moines — Denver
2h 6m stop
20:25 — 23:38
UA2028
United Airlines
Denver — San Antonio
|
6h 28m including layover |
Find flight
from$317 |
|
17:15 — 16:40
+1 day
|
17:10 — 18:19
UA1781
United Airlines
Des Moines — Denver
19h 6m stop
13:41 — 16:54
UA1022
United Airlines
Denver — San Antonio
|
23h 25m including layover |
Find flight
from$335 |
|
18:45 — 12:29
+1 day
|
18:45 — 20:22
UA5286
United Airlines
Des Moines — Chicago
12h 53m stop
09:15 — 12:29
UA1834
United Airlines
Chicago — San Antonio
|
17h 44m including layover |
Find flight
from$521 |
|
18:45 — 23:15
+1 day
|
18:45 — 20:22
UA5286
United Airlines
Des Moines — Chicago
23h 41m stop
20:03 — 23:15
UA1504
United Airlines
Chicago — San Antonio
|
28h 30m including layover |
Find flight
from$521 |
|
21:21 — 08:19
+1 day
|
18:51 — 19:57
F91677
Frontier Airlines
Des Moines — Denver
6h 46m stop
16:25 — 19:38
F92356
Frontier Airlines
Denver — San Antonio
|
10h 58m including layover |
Find flight
from$67 |
|
07:30 — 23:30
|
07:30 — 11:05
G4431
Allegiant Air
Des Moines — Newark
5h 4m stop
16:09 — 19:09
NK1861
Spirit Airlines
Newark — Orlando
2h 17m stop
21:26 — 23:30
NK446
Spirit Airlines
Orlando — San Antonio
|
16h including layover |
Find flight
from$196 |
|
07:30 — 04:59
+1 day
|
07:30 — 11:05
G4431
Allegiant Air
Des Moines — Newark
5h 38m stop
16:43 — 19:23
NK3733
Spirit Airlines
Newark — Las Vegas
5h 3m stop
00:26 — 04:59
NK1058
Spirit Airlines
Las Vegas — San Antonio
|
21h 29m including layover |
Find flight
from$196 |
Flight Information
Below we will explain in detail what the flights cost on the destination from Des Moines to San Antonio depends on and how to choose the most interesting flight option for you.
Distance between Des Moines and San Antonio is 1404 miles. Time difference between the cities is 0h. Airplanes depart 05:45 to 21:21 from 1 Des Moines airport and arrive 05:45 to 21:21 to 5 San Antonio airports. Average flight time is 10h 8m.
- The fastest flight 4h 28m
- Average flight time 10h 8m
- The earliest flight 05:45
- The latest flight 21:21
- Distance 873 ml
The cheapest months to travel to San Antonio are november (from 67 $), february (from 80 $), december (from 279 $).
The most expensive months are january (from 282 $), december (from 279 $), february (from 80 $).
What is the lowest airfare Des Moines to San Antonio?
The cheapest plane ticket found by our users is $67. This airfare is for economy class on one-way F91677 flight by Frontier Airlines for February 21, 2025 which leaves Des Moines International Airport in Des Moines at 21:21 am and arrives at San Antonio San Antonio at 08:19.
Popular Airlines on the Route
The flight Des Moines — San Antonio is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 2 departures per week at the price of from $ 67 . And the most expensive tickets are offered by United Airlines airline - from $ 685.
Direct flights
There’re no direct flights on this route. Try flights with stops.
Connecting Flights
There are 75 flights with layovers on the route. The fastest connecting flight is UA6033 by United Airlines takes 4h 28m and the cheapest is F91677 by Frontier Airlines for $67.
- F9 - Frontier Airlinesfrom $67Find
- UA - United Airlinesfrom $279Find
- G4 - Allegiant Airfrom $196Find
Airports
You can fly from Des Moines to San Antonio from 1 airports (Des Moines International Airport).
Des Moines airports
- Des Moines International Airport-DSMfrom $67Find
San Antonio airports
- Randolph AFB-RNDFind
- Martindale AAF-MDAFind
- San Antonio-SATFind
- Kelly AFB-SKFFind
- Stinson Municipal-SSFFind
Airplanes
There are flights to San Antonio from Des Moines by 3 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Des Moines
You may also consider searching for discounted plane tickets to some other popular places from Des Moines within United States.
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Top International Destinations from Des Moines
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
- from $77Find
- from $70Find
How to book a plane ticket yourself?

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