Cheap Flights from Des Moines, IA to San Antonio, TX from $61

Page navigation

Price Calendar Cheap Flights Flights Schedule

On Cheapflightsplus.com you will find 118 connecting flights from Des Moines to San Antonio. You can compare airfare deals from 6 airlines and multiple travel sites from $54, book and save on cheap plane tickets and last minute offers. Also check out DSM-SAT flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Des Moines to San Antonio Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $61 (one-way), $105 (round-trip).

Direct flights

Check to choose departure date Check to choose departure date

Check prices for return flight

Find flights

Best Flights from Des Moines to San Antonio Today

Take a look at the list of non stop flights and flights with layovers from Des Moines to San Antonio with the lowest price of $54. Take a look at the list of flights with layovers from Des Moines to San Antonio from $54. There’re no direct flights. The fastest connecting flight – 3h 32m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $54 Find flight	07:00 Des Moines Des Moines International Airport	12:02 San Antonio San Antonio	5h 2m layover 1h 3m - Chicago	United Airlines	UA5680 UA5257
from $54 Find flight	06:30 Des Moines Des Moines International Airport	11:33 San Antonio San Antonio	5h 3m layover 1h 41m - Houston	United Airlines	UA6115 UA6176
from $54 Find flight	07:53 Des Moines Des Moines International Airport	12:57 San Antonio San Antonio	5h 4m layover 1h 14m - Denver	United Airlines	UA771 UA1412
from $65 Find flight	11:58 Des Moines Des Moines International Airport	17:56 San Antonio San Antonio	5h 58m layover 0h 50m - Charlotte	American Airlines	AA5421 AA1712
from $65 Find flight	06:59 Des Moines Des Moines International Airport	13:24 San Antonio San Antonio	6h 25m layover 1h 10m - Charlotte	American Airlines	AA4377 AA1988
from $66 Find flight	15:30 Des Moines Des Moines International Airport	19:02 San Antonio San Antonio	3h 32m layover 0h 40m - Dallas	American Airlines	AA1536 AA2218

from $66 Find flight	09:30 Des Moines Des Moines International Airport	13:24 San Antonio San Antonio	3h 54m layover 0h 59m - Dallas	American Airlines	AA2326 AA35
from $66 Find flight	07:15 Des Moines Des Moines International Airport	11:33 San Antonio San Antonio	4h 18m layover 1h 13m - Dallas	American Airlines	AA5738 AA1282
from $66 Find flight	17:30 Des Moines Des Moines International Airport	21:48 San Antonio San Antonio	4h 18m layover 1h 15m - Dallas	American Airlines	AA5832 AA1406
from $66 Find flight	09:30 Des Moines Des Moines International Airport	15:44 San Antonio San Antonio	6h 14m layover 3h 19m - Dallas	American Airlines	AA2326 AA249
from $66 Find flight	15:30 Des Moines Des Moines International Airport	21:48 San Antonio San Antonio	6h 18m layover 3h 22m - Dallas	American Airlines	AA1536 AA1406
from $79 Find flight	06:00 Des Moines Des Moines International Airport	11:28 San Antonio San Antonio	5h 28m layover 2h 24m - Dallas	American Airlines	AA2326 AA1282

Show all tickets

*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 23, 2023

Flight Schedule Des Moines (Iowa) to San Antonio (Texas)

Full flight schedule will help you in detecting at what time planes fly from Des Moines to San Antonio. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
06:30 — 11:33	06:30 — 08:44 UA6115 United Airlines Des Moines — Houston 1h 41m stop 10:25 — 11:33 UA6176 United Airlines Houston — San Antonio	5h 3m including layover	Find flight from$54
07:00 — 12:02	07:00 — 08:15 UA5680 United Airlines Des Moines — Chicago 1h 3m stop 09:18 — 12:02 UA5257 United Airlines Chicago — San Antonio	5h 2m including layover	Find flight from$54
07:53 — 12:57	07:53 — 08:41 UA771 United Airlines Des Moines — Denver 1h 14m stop 09:55 — 12:57 UA1412 United Airlines Denver — San Antonio	5h 4m including layover	Find flight from$54
08:00 — 16:24	08:00 — 09:01 AA1795 American Airlines Des Moines — Phoenix 3h 9m stop 12:10 — 16:24 AA570 American Airlines Phoenix — San Antonio	8h 24m including layover	Find flight from$79
09:30 — 13:24	09:30 — 11:21 AA2326 American Airlines Des Moines — Dallas 59m stop 12:20 — 13:24 AA35 American Airlines Dallas — San Antonio	3h 54m including layover	Find flight from$66
09:30 — 15:44	09:30 — 11:21 AA2326 American Airlines Des Moines — Dallas 3h 19m stop 14:40 — 15:44 AA249 American Airlines Dallas — San Antonio	6h 14m including layover	Find flight from$66
11:58 — 17:56	11:58 — 15:20 AA5421 American Airlines Des Moines — Charlotte 50m stop 16:10 — 17:56 AA1712 American Airlines Charlotte — San Antonio	5h 58m including layover	Find flight from$65
15:09 — 22:26	15:09 — 16:29 UA4508 United Airlines Des Moines — Chicago 3h 16m stop 19:45 — 22:26 UA600 United Airlines Chicago — San Antonio	7h 17m including layover	Find flight from$54
15:30 — 19:02	15:30 — 17:20 AA1536 American Airlines Des Moines — Dallas 40m stop 18:00 — 19:02 AA2218 American Airlines Dallas — San Antonio	3h 32m including layover	Find flight from$66
16:00 — 21:55	16:00 — 19:11 DL5123 Delta Air Lines Inc. Des Moines — Atlanta 1h 24m stop 20:35 — 21:55 DL1228 Delta Air Lines Inc. Atlanta — San Antonio	5h 55m including layover	Find flight from$93
17:15 — 23:00	17:15 — 18:20 WN1558 Southwest Airlines Des Moines — Lake Saint Louis 2h 35m stop 20:55 — 23:00 WN740 Southwest Airlines Lake Saint Louis — San Antonio	5h 45m including layover	Find flight from$94
17:30 — 21:48	17:30 — 19:27 AA5832 American Airlines Des Moines — Dallas 1h 15m stop 20:42 — 21:48 AA1406 American Airlines Dallas — San Antonio	4h 18m including layover	Find flight from$66
18:10 — 12:57 +1 day	18:10 — 19:05 F9155 Frontier Airlines Des Moines — Denver 14h 50m stop 09:55 — 12:57 UA1412 United Airlines Denver — San Antonio	18h 47m including layover	Find flight from$120
21:31 — 16:45 +1 day	21:31 — 22:34 G42455 Allegiant Air Des Moines — Las Vegas 13h 31m stop 12:05 — 16:45 SY126 Sun Country Airlines Las Vegas — San Antonio	19h 14m including layover	Find flight from$130
06:17 — 13:24	06:17 — 07:45 AA3252 American Airlines Des Moines — Chicago 50m stop 08:35 — 10:59 AA2412 American Airlines Chicago — Dallas 1h 21m stop 12:20 — 13:24 AA35 American Airlines Dallas — San Antonio	7h 7m including layover	Find flight from$65
08:37 — 21:09	08:37 — 10:05 UA3591 United Airlines Des Moines — Chicago 1h 25m stop 11:30 — 13:05 UA2314 United Airlines Chicago — Denver 4h 54m stop 17:59 — 21:09 F9386 Frontier Airlines Denver — San Antonio	12h 32m including layover	Find flight from$100
11:08 — 21:55	11:08 — 12:13 DL4675 Delta Air Lines Inc. Des Moines — Minneapolis 2h 58m stop 15:11 — 18:35 DL1809 Delta Air Lines Inc. Minneapolis — Atlanta 2h stop 20:35 — 21:55 DL1228 Delta Air Lines Inc. Atlanta — San Antonio	10h 47m including layover	Find flight from$85
12:51 — 21:48	12:51 — 14:19 AA3275 American Airlines Des Moines — Chicago 41m stop 15:00 — 17:27 AA2585 American Airlines Chicago — Dallas 3h 15m stop 20:42 — 21:48 AA1406 American Airlines Dallas — San Antonio	8h 57m including layover	Find flight from$65
12:51 — 21:48	12:51 — 14:19 AA3275 American Airlines Des Moines — Chicago 3h 16m stop 17:35 — 20:02 AA2300 American Airlines Chicago — Dallas 40m stop 20:42 — 21:48 AA1406 American Airlines Dallas — San Antonio	8h 57m including layover	Find flight from$65
13:05 — 21:55	13:05 — 14:17 DL4647 Delta Air Lines Inc. Des Moines — Minneapolis 2h 16m stop 16:33 — 20:00 DL1736 Delta Air Lines Inc. Minneapolis — Atlanta 35m stop 20:35 — 21:55 DL1228 Delta Air Lines Inc. Atlanta — San Antonio	8h 50m including layover	Find flight from$85
13:05 — 21:55	13:05 — 14:17 DL4647 Delta Air Lines Inc. Des Moines — Minneapolis 54m stop 15:11 — 18:35 DL1809 Delta Air Lines Inc. Minneapolis — Atlanta 2h stop 20:35 — 21:55 DL1228 Delta Air Lines Inc. Atlanta — San Antonio	8h 50m including layover	Find flight from$85
16:17 — 16:45 +1 day	16:17 — 17:45 AA2968 American Airlines Des Moines — Chicago 2h 30m stop 20:15 — 22:09 AA2464 American Airlines Chicago — Las Vegas 13h 56m stop 12:05 — 16:45 SY126 Sun Country Airlines Las Vegas — San Antonio	24h 28m including layover	Find flight from$123
18:10 — 11:33 +1 day	18:10 — 19:05 F9155 Frontier Airlines Des Moines — Denver 10h 25m stop 05:30 — 08:52 UA1415 United Airlines Denver — Houston 1h 33m stop 10:25 — 11:33 UA6176 United Airlines Houston — San Antonio	17h 23m including layover	Find flight from$124
20:02 — 12:57 +2 days	20:02 — 21:05 G42455 Allegiant Air Des Moines — Las Vegas 19h 35m stop 16:40 — 19:41 NK799 Spirit Airlines Las Vegas — Denver 14h 14m stop 09:55 — 12:57 UA1412 United Airlines Denver — San Antonio	40h 55m including layover	Find flight from$179
21:31 — 11:33 +1 day	21:31 — 22:34 G42455 Allegiant Air Des Moines — Las Vegas 6h 26m stop 05:00 — 09:42 AA1566 American Airlines Las Vegas — Dallas 43m stop 10:25 — 11:33 AA1282 American Airlines Dallas — San Antonio	14h 2m including layover	Find flight from$138

Departuer	Arrival	Flight Details	Flight Time	Price
	stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on September 23, 2023

Flight Information

Below we will explain in detail what the flights cost on the destination from Des Moines to San Antonio depends on and how to choose the most interesting flight option for you.

Distance between Des Moines and San Antonio is 1404 miles. Time difference between the cities is 0h. Airplanes depart 06:00 to 21:31 from 1 Des Moines airport and arrive 06:00 to 21:31 to 5 San Antonio airports. Average flight time is 9h 29m.

The fastest flight 3h 32m
Average flight time 9h 29m
The earliest flight 06:00
The latest flight 21:31
Distance 873 ml

What is the lowest airfare Des Moines to San Antonio?

The cheapest plane ticket found by our users is $54. This airfare is for economy class on one-way UA6115 flight by United Airlines for August 25, 2020 which leaves Des Moines International Airport in Des Moines at 06:30 am and arrives at San Antonio San Antonio at 11:33.

Economy class

$54

Find

Business class

Find

First class

Find

Popular Airlines on the Route

The flight Des Moines — San Antonio is served by 6 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by American Airlines - 48 departures per week at the price of from $ 65 . And the most expensive tickets are offered by Delta Air Lines Inc. airline - from $ 782.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 118 flights with layovers on the route. The fastest connecting flight is AA1536 by American Airlines takes 3h 32m and the cheapest is UA6115 by United Airlines for $54.

AA - American Airlines

from $65

Find
F9 - Frontier Airlines

from $120

Find
WN - Southwest Airlines

from $94

Find
DL - Delta Air Lines Inc.

from $85

Find
UA - United Airlines

from $54

Find
G4 - Allegiant Air

from $130

Find

See more connecting flights

Airports

You can fly from Des Moines to San Antonio from 1 airports (Des Moines International Airport).

Des Moines airports

Des Moines International Airport-DSM

from $54
Find

San Antonio airports

Randolph AFB-RND

Find
Martindale AAF-MDA

Find
San Antonio-SAT

Find
Kelly AFB-SKF

Find
Stinson Municipal-SSF

Find

Airplanes

There are flights to San Antonio from Des Moines by 6 airlines that use 8 aircraft brands. They range from huge modern airplanes to small-sized.

Airbus A319

from $54

Find
Canadair Regional Jet 700

from $65

Find
Canadair Regional Jet 900

from $65

Find
Embraer 175 (short wing)

from $65

Find
Bombardier CRJ 900

from $93

Find
Embraer 175 (winglets)

from $100

Find
Bombardier CRJ 700

from $140

Find
Embraer 175

from $582

Find

Top Domestic Destinations from Des Moines

You may also consider searching for discounted plane tickets to some other popular places from Des Moines within United States.

Des Moines — Denver

from $54

Find
Des Moines — Philadelphia

from $71

Find
Des Moines — Colorado Springs

from $73

Find
Des Moines — San Antonio

from $61

Find
Des Moines — Orlando

from $74

Find
Des Moines — Chicago

from $72

Find
Des Moines — Indianapolis

from $62

Find
Des Moines — Boston

from $65

Find
Des Moines — San Diego

from $58

Find
Des Moines — El Paso

from $73

Find

Top International Destinations from Des Moines

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Des Moines — Guadalajara

from $71

Find
Des Moines — Cancun

from $77

Find
Des Moines — London

from $70

Find

All flights from Des Moines | All flights to San Antonio

How to book a plane ticket yourself?

Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
To find a plane ticket, please select dates.