Cheap Flights from Des Moines, IA to San Antonio, TX from $55

On Cheapflightsplus.com you will find 118 connecting flights from Des Moines to San Antonio. You can compare airfare deals from 6 airlines and multiple travel sites from $55, book and save on cheap plane tickets and last minute offers. Also check out DSM-SAT flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Des Moines to San Antonio Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $55 (one-way), $94 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Des Moines to San Antonio. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
06:30 — 11:33
06:30 — 08:44 UA6115 United Airlines
Des Moines — Houston
1h 41m stop
10:25 — 11:33 UA6176 United Airlines
Houston — San Antonio
5h 3m
including layover
Find flight
from$55
07:00 — 12:02
07:00 — 08:15 UA5680 United Airlines
Des Moines — Chicago
1h 3m stop
09:18 — 12:02 UA5257 United Airlines
Chicago — San Antonio
5h 2m
including layover
Find flight
from$55
07:53 — 12:57
07:53 — 08:41 UA771 United Airlines
Des Moines — Denver
1h 14m stop
09:55 — 12:57 UA1412 United Airlines
Denver — San Antonio
5h 4m
including layover
Find flight
from$55
08:00 — 16:24
08:00 — 09:01 AA1795 American Airlines
Des Moines — Phoenix
3h 9m stop
12:10 — 16:24 AA570 American Airlines
Phoenix — San Antonio
8h 24m
including layover
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from$81
09:30 — 13:24
09:30 — 11:21 AA2326 American Airlines
Des Moines — Dallas
59m stop
12:20 — 13:24 AA35 American Airlines
Dallas — San Antonio
3h 54m
including layover
Find flight
from$68
09:30 — 15:44
09:30 — 11:21 AA2326 American Airlines
Des Moines — Dallas
3h 19m stop
14:40 — 15:44 AA249 American Airlines
Dallas — San Antonio
6h 14m
including layover
Find flight
from$68
11:58 — 17:56
11:58 — 15:20 AA5421 American Airlines
Des Moines — Charlotte
50m stop
16:10 — 17:56 AA1712 American Airlines
Charlotte — San Antonio
5h 58m
including layover
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from$67
15:09 — 22:26
15:09 — 16:29 UA4508 United Airlines
Des Moines — Chicago
3h 16m stop
19:45 — 22:26 UA600 United Airlines
Chicago — San Antonio
7h 17m
including layover
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from$55
15:30 — 19:02
15:30 — 17:20 AA1536 American Airlines
Des Moines — Dallas
40m stop
18:00 — 19:02 AA2218 American Airlines
Dallas — San Antonio
3h 32m
including layover
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from$68
16:00 — 21:55
16:00 — 19:11 DL5123 Delta Air Lines Inc.
Des Moines — Atlanta
1h 24m stop
20:35 — 21:55 DL1228 Delta Air Lines Inc.
Atlanta — San Antonio
5h 55m
including layover
Find flight
from$96
17:15 — 23:00
17:15 — 18:20 WN1558 Southwest Airlines
Des Moines — Lake Saint Louis
2h 35m stop
20:55 — 23:00 WN740 Southwest Airlines
Lake Saint Louis — San Antonio
5h 45m
including layover
Find flight
from$97
17:30 — 21:48
17:30 — 19:27 AA5832 American Airlines
Des Moines — Dallas
1h 15m stop
20:42 — 21:48 AA1406 American Airlines
Dallas — San Antonio
4h 18m
including layover
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from$68
18:10 — 12:57
+1 day
18:10 — 19:05 F9155 Frontier Airlines
Des Moines — Denver
14h 50m stop
09:55 — 12:57 UA1412 United Airlines
Denver — San Antonio
18h 47m
including layover
Find flight
from$123
21:31 — 16:45
+1 day
21:31 — 22:34 G42455 Allegiant Air
Des Moines — Las Vegas
13h 31m stop
12:05 — 16:45 SY126 Sun Country Airlines
Las Vegas — San Antonio
19h 14m
including layover
Find flight
from$133
06:17 — 13:24
06:17 — 07:45 AA3252 American Airlines
Des Moines — Chicago
50m stop
08:35 — 10:59 AA2412 American Airlines
Chicago — Dallas
1h 21m stop
12:20 — 13:24 AA35 American Airlines
Dallas — San Antonio
7h 7m
including layover
Find flight
from$67
08:37 — 21:09
08:37 — 10:05 UA3591 United Airlines
Des Moines — Chicago
1h 25m stop
11:30 — 13:05 UA2314 United Airlines
Chicago — Denver
4h 54m stop
17:59 — 21:09 F9386 Frontier Airlines
Denver — San Antonio
12h 32m
including layover
Find flight
from$103
11:08 — 21:55
11:08 — 12:13 DL4675 Delta Air Lines Inc.
Des Moines — Minneapolis
2h 58m stop
15:11 — 18:35 DL1809 Delta Air Lines Inc.
Minneapolis — Atlanta
2h stop
20:35 — 21:55 DL1228 Delta Air Lines Inc.
Atlanta — San Antonio
10h 47m
including layover
Find flight
from$88
12:51 — 21:48
12:51 — 14:19 AA3275 American Airlines
Des Moines — Chicago
41m stop
15:00 — 17:27 AA2585 American Airlines
Chicago — Dallas
3h 15m stop
20:42 — 21:48 AA1406 American Airlines
Dallas — San Antonio
8h 57m
including layover
Find flight
from$67
12:51 — 21:48
12:51 — 14:19 AA3275 American Airlines
Des Moines — Chicago
3h 16m stop
17:35 — 20:02 AA2300 American Airlines
Chicago — Dallas
40m stop
20:42 — 21:48 AA1406 American Airlines
Dallas — San Antonio
8h 57m
including layover
Find flight
from$67
13:05 — 21:55
13:05 — 14:17 DL4647 Delta Air Lines Inc.
Des Moines — Minneapolis
2h 16m stop
16:33 — 20:00 DL1736 Delta Air Lines Inc.
Minneapolis — Atlanta
35m stop
20:35 — 21:55 DL1228 Delta Air Lines Inc.
Atlanta — San Antonio
8h 50m
including layover
Find flight
from$87
13:05 — 21:55
13:05 — 14:17 DL4647 Delta Air Lines Inc.
Des Moines — Minneapolis
54m stop
15:11 — 18:35 DL1809 Delta Air Lines Inc.
Minneapolis — Atlanta
2h stop
20:35 — 21:55 DL1228 Delta Air Lines Inc.
Atlanta — San Antonio
8h 50m
including layover
Find flight
from$87
16:17 — 16:45
+1 day
16:17 — 17:45 AA2968 American Airlines
Des Moines — Chicago
2h 30m stop
20:15 — 22:09 AA2464 American Airlines
Chicago — Las Vegas
13h 56m stop
12:05 — 16:45 SY126 Sun Country Airlines
Las Vegas — San Antonio
24h 28m
including layover
Find flight
from$127
18:10 — 11:33
+1 day
18:10 — 19:05 F9155 Frontier Airlines
Des Moines — Denver
10h 25m stop
05:30 — 08:52 UA1415 United Airlines
Denver — Houston
1h 33m stop
10:25 — 11:33 UA6176 United Airlines
Houston — San Antonio
17h 23m
including layover
Find flight
from$127
20:02 — 12:57
+2 days
20:02 — 21:05 G42455 Allegiant Air
Des Moines — Las Vegas
19h 35m stop
16:40 — 19:41 NK799 Spirit Airlines
Las Vegas — Denver
14h 14m stop
09:55 — 12:57 UA1412 United Airlines
Denver — San Antonio
40h 55m
including layover
Find flight
from$184
21:31 — 11:33
+1 day
21:31 — 22:34 G42455 Allegiant Air
Des Moines — Las Vegas
6h 26m stop
05:00 — 09:42 AA1566 American Airlines
Las Vegas — Dallas
43m stop
10:25 — 11:33 AA1282 American Airlines
Dallas — San Antonio
14h 2m
including layover
Find flight
from$142
*Departure and arrival times - local. Updated on June 15, 2024

Flight Information

Below we will explain in detail what the flights cost on the destination from Des Moines to San Antonio depends on and how to choose the most interesting flight option for you.

Distance between Des Moines and San Antonio is 1404 miles. Time difference between the cities is 0h. Airplanes depart 06:00 to 21:31 from 1 Des Moines airport and arrive 06:00 to 21:31 to 5 San Antonio airports. Average flight time is 9h 29m.

  • The fastest flight 3h 32m
  • Average flight time 9h 29m
  • The earliest flight 06:00
  • The latest flight 21:31
  • Distance 873 ml

What is the lowest airfare Des Moines to San Antonio?

The cheapest plane ticket found by our users is $55. This airfare is for economy class on one-way UA6115 flight by United Airlines for August 25, 2020 which leaves Des Moines International Airport in Des Moines at 06:30 am and arrives at San Antonio San Antonio at 11:33.

Economy class
$55
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Business class
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First class
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Popular Airlines on the Route

The flight Des Moines — San Antonio is served by 6 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by American Airlines - 48 departures per week at the price of from $ 67 . And the most expensive tickets are offered by Delta Air Lines Inc. airline - from $ 805.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 118 flights with layovers on the route. The fastest connecting flight is AA1536 by American Airlines takes 3h 32m and the cheapest is UA6115 by United Airlines for $55.

  • AA - American Airlines
    from $67
    Find
  • F9 - Frontier Airlines
    from $123
    Find
  • WN - Southwest Airlines
    from $97
    Find
  • DL - Delta Air Lines Inc.
    from $87
    Find
  • UA - United Airlines
    from $55
    Find
  • G4 - Allegiant Air
    from $133
    Find
See more connecting flights

Airports

You can fly from Des Moines to San Antonio from 1 airports (Des Moines International Airport).

Des Moines airports

  • Des Moines International Airport-DSM
    from $55
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San Antonio airports

  • Randolph AFB-RND
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  • Martindale AAF-MDA
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  • San Antonio-SAT
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  • Kelly AFB-SKF
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  • Stinson Municipal-SSF
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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