Cheap Flights from San Antonio, TX to Des Moines, IA from $213

Return flight: Des Moines – San Antonio
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On Cheapflightsplus.com you will find 20 connecting flights from San Antonio to Des Moines. You can compare airfare deals from 2 airlines and multiple travel sites from $213, book and save on cheap plane tickets and last minute offers. Also check out SAT-DSM flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip San Antonio to Des Moines Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $213 (one-way), $365 (round-trip).
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Best Flights from San Antonio to Des Moines Today

Take a look at the list of non stop flights and flights with layovers from San Antonio to Des Moines with the lowest price of $213. Take a look at the list of flights with layovers from San Antonio to Des Moines from $213. There’re no direct flights. The fastest connecting flight – 4h 31m.
Price Departure Arrival Flight Duration Airline Flight
from $213
Find flight
13:26
San Antonio
San Antonio
 22:52
Des Moines
Des Moines International Airport
 9h 26m
layover
3h 49m - Las Vegas
 Spirit Airlines
NK463
G42100
from $232
Find flight
09:45
San Antonio
San Antonio
 14:16
Des Moines
Des Moines International Airport
 4h 31m
layover
1h 6m - Houston
 United Airlines
UA2105
UA6166
from $232
Find flight
13:18
San Antonio
San Antonio
 20:39
Des Moines
Des Moines International Airport
 7h 21m
layover
3h 13m - Denver
 United Airlines
UA1299
UA1925
from $235
Find flight
14:15
San Antonio
San Antonio
 21:23
Des Moines
Des Moines International Airport
 7h 8m
layover
2h 46m - Chicago
 United Airlines
UA2243
UA617
from $262
Find flight
07:27
San Antonio
San Antonio
 14:16
Des Moines
Des Moines International Airport
 6h 49m
layover
3h 24m - Houston
 United Airlines
UA1486
UA6166
from $267
Find flight
17:57
San Antonio
San Antonio
 22:30
Des Moines
Des Moines International Airport
 4h 33m
layover
1h 2m - Houston
 United Airlines
UA465
UA1780
from $296
Find flight
09:00
San Antonio
San Antonio
 16:11
Des Moines
Des Moines International Airport
 7h 11m
layover
3h 7m - Denver
 United Airlines
UA791
UA2265
from $301
Find flight
16:50
San Antonio
San Antonio
 23:30
Des Moines
Des Moines International Airport
 6h 40m
layover
2h 24m - Denver
 United Airlines
UA680
UA5445
from $310
Find flight
13:18
San Antonio
San Antonio
 23:30
Des Moines
Des Moines International Airport
 10h 12m
layover
5h 56m - Denver
 United Airlines
UA1299
UA5445
from $310
Find flight
13:18
San Antonio
San Antonio
 12:50+1 день
Des Moines
Des Moines International Airport
 23h 32m
layover
19h 13m - Denver
 United Airlines
UA1299
UA5350
from $325
Find flight
09:00
San Antonio
San Antonio
 20:39
Des Moines
Des Moines International Airport
 11h 39m
layover
7h 32m - Denver
 United Airlines
UA791
UA1925
from $332
Find flight
09:00
San Antonio
San Antonio
 23:30
Des Moines
Des Moines International Airport
 14h 30m
layover
10h 15m - Denver
 United Airlines
UA791
UA5445
from $332
Find flight
09:00
San Antonio
San Antonio
 12:50+1 день
Des Moines
Des Moines International Airport
 27h 50m
layover
23h 32m - Denver
 United Airlines
UA791
UA5350
from $337
Find flight
16:19
San Antonio
San Antonio
 22:30
Des Moines
Des Moines International Airport
 6h 11m
layover
2h 40m - Houston
 United Airlines
UA2157
UA1780
from $456
Find flight
12:26
San Antonio
San Antonio
 22:30
Des Moines
Des Moines International Airport
 10h 4m
layover
6h 35m - Houston
 United Airlines
UA1282
UA1780
from $244
Find flight
13:26
San Antonio
San Antonio
 14:42+1 день
Des Moines
Des Moines International Airport
 25h 16m
layover
8h 37m - Las Vegas
6h 28m - Clearwater
 Spirit Airlines
NK463
NK900
G42070
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on February 23, 2025
Full flight schedule will help you in detecting at what time planes fly from San Antonio to Des Moines. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
05:30 — 14:16
05:15 — 06:21 UA469 United Airlines
San Antonio — Houston
5h 21m stop
11:55 — 14:17 UA6166 United Airlines
Houston — Des Moines
8h 46m
including layover
Find flight
from$469
07:00 — 14:29
07:00 — 09:51 UA2629 United Airlines
San Antonio — Chicago
3h 5m stop
12:56 — 14:29 UA4397 United Airlines
Chicago — Des Moines
7h 29m
including layover
Find flight
from$521
07:27 — 14:16
07:18 — 08:22 UA1486 United Airlines
San Antonio — Houston
3h 24m stop
11:55 — 14:17 UA6166 United Airlines
Houston — Des Moines
6h 49m
including layover
Find flight
from$262
09:00 — 16:11
08:49 — 10:11 UA791 United Airlines
San Antonio — Denver
3h 7m stop
13:26 — 16:10 UA2265 United Airlines
Denver — Des Moines
7h 11m
including layover
Find flight
from$296
09:00 — 20:39
09:00 — 10:23 UA791 United Airlines
San Antonio — Denver
7h 32m stop
17:55 — 20:39 UA1925 United Airlines
Denver — Des Moines
11h 39m
including layover
Find flight
from$325
09:00 — 23:30
09:00 — 10:23 UA791 United Airlines
San Antonio — Denver
10h 15m stop
20:38 — 23:30 UA5445 United Airlines
Denver — Des Moines
14h 30m
including layover
Find flight
from$332
09:00 — 12:50
+1 day
08:49 — 10:11 UA791 United Airlines
San Antonio — Denver
23h 32m stop
09:55 — 12:51 UA5350 United Airlines
Denver — Des Moines
27h 50m
including layover
Find flight
from$332
09:45 — 14:16
09:40 — 10:47 UA2105 United Airlines
San Antonio — Houston
1h 6m stop
11:55 — 14:24 UA6166 United Airlines
Houston — Des Moines
4h 31m
including layover
Find flight
from$232
12:26 — 22:30
12:26 — 13:30 UA1282 United Airlines
San Antonio — Houston
6h 35m stop
20:05 — 22:30 UA1780 United Airlines
Houston — Des Moines
10h 4m
including layover
Find flight
from$456
13:18 — 20:39
13:00 — 14:24 UA1299 United Airlines
San Antonio — Denver
3h 13m stop
17:50 — 20:36 UA1925 United Airlines
Denver — Des Moines
7h 21m
including layover
Find flight
from$232
13:18 — 23:30
13:18 — 14:42 UA1299 United Airlines
San Antonio — Denver
5h 56m stop
20:38 — 23:30 UA5445 United Airlines
Denver — Des Moines
10h 12m
including layover
Find flight
from$310
13:18 — 12:50
+1 day
13:18 — 14:42 UA1299 United Airlines
San Antonio — Denver
19h 13m stop
09:55 — 12:50 UA5350 United Airlines
Denver — Des Moines
23h 32m
including layover
Find flight
from$310
13:26 — 22:52
13:26 — 14:08 NK463 Spirit Airlines
San Antonio — Las Vegas
3h 49m stop
17:57 — 22:52 G42100 Allegiant Air
Las Vegas — Des Moines
9h 26m
including layover
Find flight
from$213
14:15 — 21:23
14:15 — 17:04 UA2243 United Airlines
San Antonio — Chicago
2h 46m stop
19:50 — 21:23 UA617 United Airlines
Chicago — Des Moines
7h 8m
including layover
Find flight
from$235
14:31 — 22:30
14:31 — 15:40 UA2498 United Airlines
San Antonio — Houston
4h 25m stop
20:05 — 22:30 UA1780 United Airlines
Houston — Des Moines
7h 59m
including layover
Find flight
from$478
16:19 — 22:30
16:19 — 17:25 UA2157 United Airlines
San Antonio — Houston
2h 40m stop
20:05 — 22:30 UA1780 United Airlines
Houston — Des Moines
6h 11m
including layover
Find flight
from$337
16:50 — 23:30
16:50 — 18:14 UA680 United Airlines
San Antonio — Denver
2h 24m stop
20:38 — 23:30 UA5445 United Airlines
Denver — Des Moines
6h 40m
including layover
Find flight
from$301
17:57 — 22:30
17:57 — 19:03 UA465 United Airlines
San Antonio — Houston
1h 2m stop
20:05 — 22:30 UA1780 United Airlines
Houston — Des Moines
4h 33m
including layover
Find flight
from$267
13:26 — 14:42
+1 day
13:26 — 14:08 NK463 Spirit Airlines
San Antonio — Las Vegas
8h 37m stop
22:45 — 06:08 NK900 Spirit Airlines
Las Vegas — Clearwater
6h 28m stop
12:36 — 14:42 G42070 Allegiant Air
Clearwater — Des Moines
25h 16m
including layover
Find flight
from$244
13:26 — 12:44
+1 day
13:26 — 14:08 NK463 Spirit Airlines
San Antonio — Las Vegas
9h 37m stop
23:45 — 07:22 NK1853 Spirit Airlines
Las Vegas — Sanford
3h 14m stop
10:36 — 12:44 G42080 Allegiant Air
Sanford — Des Moines
23h 18m
including layover
Find flight
from$276
*Departure and arrival times - local. Updated on February 23, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from San Antonio to Des Moines depends on and how to choose the most interesting flight option for you.

Distance between San Antonio and Des Moines is 1404 miles. Time difference between the cities is 0h. Airplanes depart 05:30 to 17:57 from 5 San Antonio airports and arrive 05:30 to 17:57 to 1 Des Moines airport. Average flight time is 8h 23m.

  • The fastest flight 4h 31m
  • Average flight time 8h 23m
  • The earliest flight 05:30
  • The latest flight 17:57
  • Distance 873 ml

The cheapest months to travel to Des Moines are february (from 213 $), january (from 232 $), november (from 262 $).

The most expensive months are december (from 296 $), november (from 262 $), january (from 232 $).

What is the lowest airfare San Antonio to Des Moines?

The cheapest plane ticket found by our users is $213. This airfare is for economy class on one-way NK463 flight by Spirit Airlines for February 21, 2025 which leaves San Antonio in San Antonio at 13:26 am and arrives at Des Moines Des Moines International Airport at 22:52.

Economy class
$213
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Business class
?
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First class
?
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Popular Airlines on the Route

The flight San Antonio — Des Moines is served by 2 regular airlines and 1 low-cost airline. Most of the flights on this route are operated by United Airlines - 17 departures per week at the price of from $ 232 . And the most expensive tickets are offered by United Airlines airline - from $ 521.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 20 flights with layovers on the route. The fastest connecting flight is UA2105 by United Airlines takes 4h 31m and the cheapest is NK463 by Spirit Airlines for $213.

  • UA - United Airlines
    from $232
    Find
  • NK - Spirit Airlines
    from $213
    Find
See more connecting flights

Airports

You can fly from San Antonio to Des Moines from 5 airports (Randolph AFB, Martindale AAF, San Antonio, Kelly AFB, Stinson Municipal).

San Antonio airports

  • Randolph AFB-RND
    Find
  • Martindale AAF-MDA
    Find
  • San Antonio-SAT
    from $213
    Find
  • Kelly AFB-SKF
    Find
  • Stinson Municipal-SSF
    Find

Des Moines airports

  • Des Moines International Airport-DSM
    Find

Airplanes

There are flights to Des Moines from San Antonio by 2 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from San Antonio

You may also consider searching for discounted plane tickets to some other popular places from San Antonio within United States.

Top International Destinations from San Antonio

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

How to book a plane ticket yourself?

How to book an air ticket yourself?
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  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

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