Cheap Flights from San Antonio, TX to Des Moines, IA from $97

On Cheapflightsplus.com you will find 140 connecting flights from San Antonio to Des Moines. You can compare airfare deals from 4 airlines and multiple travel sites from $97, book and save on cheap plane tickets and last minute offers. Also check out SAT-DSM flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from San Antonio to Des Moines depends on and how to choose the most interesting flight option for you.

Distance between San Antonio and Des Moines is 1404 miles. Time difference between the cities is 0h. Airplanes depart 05:00 to 22:57 from 5 San Antonio airports and arrive 05:00 to 22:57 to 1 Des Moines airport. Average flight time is 19h 24m.

  • The fastest flight 4h 20m
  • Average flight time 19h 24m
  • The earliest flight 05:00
  • The latest flight 22:57
  • Distance 873 ml

The cheapest months to travel to Des Moines are july (from 97 $), august (from 97 $), october (from 188 $).

The most expensive months are february (from 620 $), december (from 433 $), november (from 311 $).

What is the lowest airfare San Antonio to Des Moines?

The cheapest plane ticket found by our users is $97. This airfare is for economy class on one-way NK1876 flight by Spirit Airlines for August 7, 2025 which leaves San Antonio in San Antonio at 17:38 am and arrives at Des Moines Des Moines International Airport at 18:05.

Economy class
$97
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Business class
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First class
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Flight Schedule San Antonio (Texas) to Des Moines (Iowa)

05:15 — 10:36
5h 21m flight time
Find flight
from$192
05:15 — 06:34 San Antonio — Denver
UA1399 United Airlines
1h 11m stop
07:45 — 10:36 Denver — Des Moines
UA5718 United Airlines
06:30 — 12:23
5h 53m flight time
Find flight
from$194
06:30 — 09:29 San Antonio — Chicago
UA2008 United Airlines
1h 18m stop
10:47 — 12:23 Chicago — Des Moines
UA5446 United Airlines
06:45 — 14:44
7h 59m flight time
Find flight
from$192
06:45 — 09:44 San Antonio — Chicago
UA2629 United Airlines
3h 28m stop
13:12 — 14:44 Chicago — Des Moines
UA3535 United Airlines
07:30 — 14:16
6h 46m flight time
Find flight
from$192
07:18 — 08:22 San Antonio — Houston
UA1486 United Airlines
3h 19m stop
11:55 — 14:17 Houston — Des Moines
UA6166 United Airlines
08:33 — 13:31+1day
28h 58m flight time
Find flight
from$178
08:33 — 12:17 San Antonio — Sanford
NK1359 Spirit Airlines
23h 21m stop
11:38 — 13:31 Sanford — Des Moines
G4434 Allegiant Air
08:55 — 16:10
7h 15m flight time
Find flight
from$192
08:55 — 10:12 San Antonio — Denver
UA1424 United Airlines
3h 13m stop
13:25 — 16:10 Denver — Des Moines
UA2265 United Airlines
09:56 — 14:16
4h 20m flight time
Find flight
from$192
09:39 — 10:45 San Antonio — Houston
UA1798 United Airlines
53m stop
11:55 — 14:16 Houston — Des Moines
UA6166 United Airlines
16:21 — 22:17
5h 56m flight time
Find flight
from$192
16:21 — 17:25 San Antonio — Houston
UA1066 United Airlines
2h 30m stop
19:55 — 22:17 Houston — Des Moines
UA1780 United Airlines
16:36 — 23:59
7h 23m flight time
Find flight
from$192
16:30 — 18:02 San Antonio — Denver
UA624 United Airlines
2h 55m stop
21:03 — 23:59 Denver — Des Moines
UA5954 United Airlines
17:38 — 18:05+1day
24h 27m flight time
Find flight
from$97
17:38 — 19:51 San Antonio — Nashville
NK1876 Spirit Airlines
20h 34m stop
16:26 — 18:06 Nashville — Des Moines
G4448 Allegiant Air
17:38 — 22:38
5h flight time
Find flight
from$104
17:38 — 19:51 San Antonio — Nashville
NK1876 Spirit Airlines
1h 7m stop
20:58 — 22:38 Nashville — Des Moines
G4466 Allegiant Air
17:38 — 22:38
5h flight time
Find flight
from$119
17:38 — 19:51 San Antonio — Nashville
NK1876 Spirit Airlines
1h 7m stop
20:58 — 22:38 Nashville — Des Moines
G4442 Allegiant Air
17:56 — 22:17
4h 21m flight time
Find flight
from$192
17:56 — 19:02 San Antonio — Houston
UA2170 United Airlines
53m stop
19:55 — 22:17 Houston — Des Moines
UA1780 United Airlines
18:13 — 18:06+1day
23h 53m flight time
Find flight
from$106
18:16 — 20:26 San Antonio — Nashville
NK2039 Spirit Airlines
20h stop
18:27 — 20:09 Nashville — Des Moines
G4442 Allegiant Air
20:14 — 18:48+1day
22h 34m flight time
Find flight
from$113
20:14 — 21:45 San Antonio — Denver
F92097 Frontier Airlines
18h 15m stop
16:00 — 18:48 Denver — Des Moines
F91678 Frontier Airlines
Full flight schedule will help you in detecting at what time planes fly from San Antonio to Des Moines. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on October 19, 2025.

Popular Airlines on the Route

The flight San Antonio — Des Moines is served by 4 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 1 departures per week at the price of from $ 113 . And the most expensive tickets are offered by United Airlines airline - from $ 493.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 140 flights with layovers on the route. The fastest connecting flight is UA1798 by United Airlines takes 4h 20m and the cheapest is NK1876 by Spirit Airlines for $97.

  • F9 - Frontier Airlines
    from $113
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  • SY - Sun Country Airlines
    from $243
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  • UA - United Airlines
    from $192
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  • NK - Spirit Airlines
    from $97
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See more connecting flights

Airports

You can fly from San Antonio to Des Moines from 5 airports (Randolph AFB, Martindale AAF, San Antonio, Kelly AFB, Stinson Municipal).

San Antonio airports

  • Randolph AFB-RND
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  • Martindale AAF-MDA
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  • San Antonio-SAT
    from $97
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  • Kelly AFB-SKF
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  • Stinson Municipal-SSF
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Des Moines airports

  • Des Moines International Airport-DSM
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

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