Cheap Flights from San Antonio, TX to Des Moines, IA from $102
Return flight: Des Moines – San Antonio
On Cheapflightsplus.com you will find 73 connecting flights from San Antonio to Des Moines. You can compare airfare deals from 3 airlines and multiple travel sites from $102, book and save on cheap plane tickets and last minute offers. Also check out SAT-DSM flight schedule to find best flight time, convenient departure and arrival airports.
Find One-Way and Round-Trip San Antonio to Des Moines Flight Deals
To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights».
To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight.
Cheapest flights in November: $102 (one-way), $175 (round-trip).
Direct flights
Check prices for return flight
Best Flights from San Antonio to Des Moines Today
Take a look at the list of non stop flights and flights with layovers from San Antonio to Des Moines with the lowest price of $102. Take a look at the list of flights with layovers from San Antonio to Des Moines from $102. There’re no direct flights. The fastest connecting flight – 4h 20m.
| Price | Departure | Arrival | Flight Duration | Airline | Flight |
|---|---|---|---|---|---|
| from $102 | 17:38 San Antonio San Antonio | 18:05+1 день Des Moines Des Moines International Airport | 24h 27m layover 20h 34m - Nashville | Spirit Airlines | NK1876 G4448 |
| from $112 | 18:13 San Antonio San Antonio | 18:06+1 день Des Moines Des Moines International Airport | 23h 53m layover 20h 0m - Nashville | Spirit Airlines | NK2039 G4442 |
| from $187 | 08:33 San Antonio San Antonio | 13:31+1 день Des Moines Des Moines International Airport | 28h 58m layover 23h 21m - Sanford | Spirit Airlines | NK1359 G4434 |
| from $202 | 09:56 San Antonio San Antonio | 14:16 Des Moines Des Moines International Airport | 4h 20m layover 0h 53m - Houston | United Airlines | UA1798 UA6166 |
| from $202 | 17:56 San Antonio San Antonio | 22:17 Des Moines Des Moines International Airport | 4h 21m layover 0h 53m - Houston | United Airlines | UA2170 UA1780 |
| from $202 | 05:15 San Antonio San Antonio | 10:36 Des Moines Des Moines International Airport | 5h 21m layover 1h 11m - Denver | United Airlines | UA1399 UA5718 |
| from $202 | 16:21 San Antonio San Antonio | 22:17 Des Moines Des Moines International Airport | 5h 56m layover 2h 30m - Houston | United Airlines | UA1066 UA1780 |
| from $202 | 07:30 San Antonio San Antonio | 14:16 Des Moines Des Moines International Airport | 6h 46m layover 3h 19m - Houston | United Airlines | UA1486 UA6166 |
| from $202 | 08:55 San Antonio San Antonio | 16:10 Des Moines Des Moines International Airport | 7h 15m layover 3h 13m - Denver | United Airlines | UA1424 UA2265 |
| from $202 | 16:36 San Antonio San Antonio | 23:59 Des Moines Des Moines International Airport | 7h 23m layover 2h 55m - Denver | United Airlines | UA624 UA5954 |
| from $138 | 08:33 San Antonio San Antonio | 18:05+1 день Des Moines Des Moines International Airport | 33h 32m layover 3h 28m - Orlando 23h 36m - Nashville | Spirit Airlines | NK1359 NK1456 G4448 |
| from $156 | 19:38 San Antonio San Antonio | 13:31+1 день Des Moines Des Moines International Airport | 17h 53m layover 4h 14m - Las Vegas 3h 17m - Sanford | Spirit Airlines | NK1587 NK1372 G4434 |
| from $165 | 07:10 San Antonio San Antonio | 22:38 Des Moines Des Moines International Airport | 15h 28m layover 3h 15m - Miami 5h 29m - Nashville | Spirit Airlines | NK1463 NK2047 G4466 |
| from $196 | 08:00 San Antonio San Antonio | 18:25 Des Moines Des Moines International Airport | 10h 25m layover 1h 34m - Tampa 2h 49m - Nashville | Spirit Airlines | NK450 NK2032 G4328 |
| from $198 | 14:50 San Antonio San Antonio | 14:27+1 день Des Moines Des Moines International Airport | 23h 37m layover 4h 28m - Los Angeles 11h 38m - Las Vegas | Spirit Airlines | NK849 NK473 G4474 |
| from $199 | 06:00 San Antonio San Antonio | 17:48 Des Moines Des Moines International Airport | 11h 48m layover 2h 28m - Las Vegas 1h 13m - Nashville | Spirit Airlines | NK1059 NK2332 G4442 |
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on July 14, 2025
Flight Schedule San Antonio (Texas) to Des Moines (Iowa)
Full flight schedule will help you in detecting at what time planes fly from San Antonio to Des Moines. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
| Departure | Arrival | Flight Details | Flight Duration | Price |
|---|---|---|---|---|
|
05:15 — 10:36
|
05:15 — 06:34
UA1399
United Airlines
San Antonio — Denver
1h 11m stop
07:45 — 10:36
UA5718
United Airlines
Denver — Des Moines
|
5h 21m including layover |
Find flight
from$202 |
|
|
07:30 — 14:16
|
07:18 — 08:22
UA1486
United Airlines
San Antonio — Houston
3h 19m stop
11:55 — 14:17
UA6166
United Airlines
Houston — Des Moines
|
6h 46m including layover |
Find flight
from$202 |
|
|
09:50 — 14:17
|
09:50 — 10:56
UA349
United Airlines
San Antonio — Houston
1h 1m stop
11:57 — 14:17
UA6166
United Airlines
Houston — Des Moines
|
4h 27m including layover |
Find flight
from$204 |
|
|
09:56 — 14:16
|
09:39 — 10:45
UA1798
United Airlines
San Antonio — Houston
53m stop
11:55 — 14:16
UA6166
United Airlines
Houston — Des Moines
|
4h 20m including layover |
Find flight
from$202 |
|
|
12:55 — 21:47
|
12:55 — 15:53
UA1905
United Airlines
San Antonio — Chicago
4h 27m stop
20:20 — 21:47
UA1531
United Airlines
Chicago — Des Moines
|
8h 52m including layover |
Find flight
from$474 |
|
|
12:57 — 21:45
|
12:57 — 15:53
UA1905
United Airlines
San Antonio — Chicago
4h 22m stop
20:15 — 21:45
UA661
United Airlines
Chicago — Des Moines
|
8h 48m including layover |
Find flight
from$475 |
|
|
13:43 — 20:15
|
13:43 — 15:00
UA1299
United Airlines
San Antonio — Denver
2h 30m stop
17:30 — 20:15
UA1488
United Airlines
Denver — Des Moines
|
6h 32m including layover |
Find flight
from$228 |
|
|
13:44 — 20:29
|
13:44 — 15:00
UA490
United Airlines
San Antonio — Denver
2h 42m stop
17:42 — 20:29
UA1925
United Airlines
Denver — Des Moines
|
6h 45m including layover |
Find flight
from$239 |
|
|
14:15 — 22:17
|
14:15 — 15:25
UA6050
United Airlines
San Antonio — Houston
4h 30m stop
19:55 — 22:17
UA1780
United Airlines
Houston — Des Moines
|
8h 2m including layover |
Find flight
from$399 |
|
|
16:21 — 22:17
|
16:21 — 17:25
UA1066
United Airlines
San Antonio — Houston
2h 30m stop
19:55 — 22:17
UA1780
United Airlines
Houston — Des Moines
|
5h 56m including layover |
Find flight
from$202 |
|
|
16:36 — 23:59
|
16:30 — 18:02
UA624
United Airlines
San Antonio — Denver
2h 55m stop
21:03 — 23:59
UA5954
United Airlines
Denver — Des Moines
|
7h 23m including layover |
Find flight
from$202 |
|
|
17:38 — 18:05
+1 day
|
17:38 — 19:51
NK1876
Spirit Airlines
San Antonio — Nashville
20h 34m stop
16:26 — 18:06
G4448
Allegiant Air
Nashville — Des Moines
|
24h 27m including layover |
Find flight
from$102 |
|
|
17:38 — 22:38
|
17:38 — 19:51
NK1876
Spirit Airlines
San Antonio — Nashville
1h 7m stop
20:58 — 22:38
G4466
Allegiant Air
Nashville — Des Moines
|
5h including layover |
Find flight
from$110 |
|
|
18:13 — 18:06
+1 day
|
18:16 — 20:26
NK2039
Spirit Airlines
San Antonio — Nashville
20h stop
18:27 — 20:09
G4442
Allegiant Air
Nashville — Des Moines
|
23h 53m including layover |
Find flight
from$112 |
|
|
05:20 — 23:27
+1 day
|
05:20 — 09:06
NK447
Spirit Airlines
San Antonio — Orlando
13h 55m stop
23:01 — 23:59
NK525
Spirit Airlines
Orlando — Nashville
21h 46m stop
21:45 — 23:27
G4442
Allegiant Air
Nashville — Des Moines
|
42h 7m including layover |
Find flight
from$207 |
|
|
06:00 — 17:48
|
06:00 — 06:44
NK1059
Spirit Airlines
San Antonio — Las Vegas
2h 28m stop
09:12 — 14:53
NK2332
Spirit Airlines
Las Vegas — Nashville
1h 13m stop
16:06 — 17:48
G4442
Allegiant Air
Nashville — Des Moines
|
11h 48m including layover |
Find flight
from$199 |
|
|
06:00 — 16:25
+1 day
|
06:00 — 06:44
NK1059
Spirit Airlines
San Antonio — Las Vegas
2h 28m stop
09:12 — 14:53
NK2332
Spirit Airlines
Las Vegas — Nashville
23h 51m stop
14:44 — 16:25
G4313
Allegiant Air
Nashville — Des Moines
|
34h 25m including layover |
Find flight
from$202 |
|
|
07:10 — 22:38
|
07:10 — 11:00
NK1463
Spirit Airlines
San Antonio — Miami
3h 15m stop
14:15 — 15:29
NK2047
Spirit Airlines
Miami — Nashville
5h 29m stop
20:58 — 22:38
G4466
Allegiant Air
Nashville — Des Moines
|
15h 28m including layover |
Find flight
from$165 |
|
|
08:33 — 18:05
+1 day
|
08:33 — 12:17
NK1359
Spirit Airlines
San Antonio — Orlando
3h 28m stop
15:45 — 16:49
NK1456
Spirit Airlines
Orlando — Nashville
23h 36m stop
16:25 — 18:05
G4448
Allegiant Air
Nashville — Des Moines
|
33h 32m including layover |
Find flight
from$138 |
|
|
08:33 — 22:38
|
08:33 — 12:17
NK1359
Spirit Airlines
San Antonio — Orlando
3h 28m stop
15:45 — 16:49
NK1456
Spirit Airlines
Orlando — Nashville
4h 9m stop
20:58 — 22:38
G4466
Allegiant Air
Nashville — Des Moines
|
14h 5m including layover |
Find flight
from$143 |
|
|
14:50 — 14:27
+1 day
|
14:50 — 16:02
NK849
Spirit Airlines
San Antonio — Los Angeles
4h 28m stop
20:30 — 21:53
NK473
Spirit Airlines
Los Angeles — Las Vegas
11h 38m stop
09:31 — 14:27
G4474
Allegiant Air
Las Vegas — Des Moines
|
23h 37m including layover |
Find flight
from$198 |
|
|
19:38 — 13:31
+1 day
|
19:38 — 20:38
NK1587
Spirit Airlines
San Antonio — Las Vegas
4h 14m stop
00:52 — 08:21
NK1372
Spirit Airlines
Las Vegas — Sanford
3h 17m stop
11:38 — 13:31
G4434
Allegiant Air
Sanford — Des Moines
|
17h 53m including layover |
Find flight
from$156 |
|
*Departure and arrival times - local. Updated on July 14, 2025
Flight Information
Below we will explain in detail what the flights cost on the destination from San Antonio to Des Moines depends on and how to choose the most interesting flight option for you.
Distance between San Antonio and Des Moines is 1404 miles. Time difference between the cities is 0h. Airplanes depart 05:15 to 19:38 from 5 San Antonio airports and arrive 05:15 to 19:38 to 1 Des Moines airport. Average flight time is 11h 20m.
- The fastest flight 4h 20m
- Average flight time 11h 20m
- The earliest flight 05:15
- The latest flight 19:38
- Distance 873 ml
The cheapest months to travel to Des Moines are july (from 102 $), august (from 102 $), october (from 198 $).
The most expensive months are february (from 652 $), december (from 456 $), november (from 328 $).
What is the lowest airfare San Antonio to Des Moines?
The cheapest plane ticket found by our users is $102. This airfare is for economy class on one-way NK1876 flight by Spirit Airlines for August 7, 2025 which leaves San Antonio in San Antonio at 17:38 am and arrives at Des Moines Des Moines International Airport at 18:05.
Economy class
$102
Business class
?
First class
?
Popular Airlines on the Route
The flight San Antonio — Des Moines is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Sun Country Airlines - 3 departures per week at the price of from $ 256 . And the most expensive tickets are offered by United Airlines airline - from $ 524.
Direct flights
There’re no direct flights on this route. Try flights with stops.
Connecting Flights
There are 73 flights with layovers on the route. The fastest connecting flight is UA1798 by United Airlines takes 4h 20m and the cheapest is NK1876 by Spirit Airlines for $102.
- SY - Sun Country Airlinesfrom $256Find
- UA - United Airlinesfrom $202Find
- NK - Spirit Airlinesfrom $102Find
See more connecting flights
Airports
You can fly from San Antonio to Des Moines from 5 airports (Randolph AFB, Martindale AAF, San Antonio, Kelly AFB, Stinson Municipal).
San Antonio airports
- Randolph AFB-RNDFind
- Martindale AAF-MDAFind
- San Antonio-SATfrom $102Find
- Kelly AFB-SKFFind
- Stinson Municipal-SSFFind
Des Moines airports
- Des Moines International Airport-DSMFind
Airplanes
There are flights to Des Moines from San Antonio by 3 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from San Antonio
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Top International Destinations from San Antonio
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
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How to book a plane ticket yourself?
- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
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