Cheap Flights from Des Moines, IA to Indianapolis, IN from $67

One way Round trip

Adults

Children under 12

Infants under 2 without place

Economy

Business

First

done

Return flight: Indianapolis – Des Moines

Page navigation

Price Calendar Cheap Flights Flights Schedule

On Cheapflightsplus.com you will find 144 connecting flights from Des Moines to Indianapolis. You can compare airfare deals from 3 airlines and multiple travel sites from $67, book and save on cheap plane tickets and last minute offers. Also check out DSM-IND flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Des Moines to Indianapolis Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $67 (one-way), $115 (round-trip).

Direct flights

Check to choose departure date Check to choose departure date

Check prices for return flight

Find flights

Best Flights from Des Moines to Indianapolis Today

Take a look at the list of non stop flights and flights with layovers from Des Moines to Indianapolis with the lowest price of $67. Take a look at the list of flights with layovers from Des Moines to Indianapolis from $67. There’re no direct flights. The fastest connecting flight – 3h 15m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $67 Find flight	21:21 Des Moines Des Moines International Airport	10:21+1 день Indianapolis Indianapolis Int.	12h 0m layover 7h 27m - Denver	Frontier Airlines	F91677 F92348
from $139 Find flight	07:00 Des Moines Des Moines International Airport	18:46 Indianapolis Indianapolis Int.	10h 46m layover 5h 32m - Tampa	Allegiant Air	G4431 NK150
from $222 Find flight	08:57 Des Moines Des Moines International Airport	20:31 Indianapolis Indianapolis Int.	10h 34m layover 5h 37m - Sanford	Allegiant Air	G41341 G42848
from $226 Find flight	09:00 Des Moines Des Moines International Airport	20:03 Indianapolis Indianapolis Int.	10h 3m layover 4h 55m - Sanford	Allegiant Air	G4464 G42245
from $236 Find flight	18:54 Des Moines Des Moines International Airport	23:14 Indianapolis Indianapolis Int.	3h 20m layover 0h 45m - Chicago	United Airlines	UA3433 UA3650
from $237 Find flight	15:27 Des Moines Des Moines International Airport	20:05 Indianapolis Indianapolis Int.	3h 38m layover 0h 45m - Chicago	United Airlines	UA3457 UA3628
from $237 Find flight	18:45 Des Moines Des Moines International Airport	23:30 Indianapolis Indianapolis Int.	3h 45m layover 0h 55m - Chicago	United Airlines	UA5286 UA3650
from $237 Find flight	08:00 Des Moines Des Moines International Airport	12:51 Indianapolis Indianapolis Int.	3h 51m layover 1h 1m - Chicago	United Airlines	UA1363 UA3426
from $237 Find flight	11:35 Des Moines Des Moines International Airport	16:50 Indianapolis Indianapolis Int.	4h 15m layover 1h 25m - Chicago	United Airlines	UA2306 UA3657
from $237 Find flight	11:35 Des Moines Des Moines International Airport	18:10 Indianapolis Indianapolis Int.	5h 35m layover 2h 45m - Chicago	United Airlines	UA2306 UA3690
from $237 Find flight	15:27 Des Moines Des Moines International Airport	22:05 Indianapolis Indianapolis Int.	5h 38m layover 2h 47m - Chicago	United Airlines	UA3457 UA3707
from $238 Find flight	11:29 Des Moines Des Moines International Airport	17:48 Indianapolis Indianapolis Int.	5h 19m layover 2h 43m - Chicago	United Airlines	UA1373 UA3690
from $238 Find flight	08:00 Des Moines Des Moines International Airport	15:08 Indianapolis Indianapolis Int.	6h 8m layover 3h 32m - Chicago	United Airlines	UA1363 UA3518
from $246 Find flight	08:00 Des Moines Des Moines International Airport	18:46 Indianapolis Indianapolis Int.	9h 46m layover 2h 49m - Las Vegas	Allegiant Air	G4442 G4612
from $286 Find flight	18:54 Des Moines Des Moines International Airport	23:09 Indianapolis Indianapolis Int.	3h 15m layover 0h 43m - Chicago	United Airlines	UA1807 UA3650
from $243 Find flight	15:35 Des Moines Des Moines International Airport	11:06+1 день Indianapolis Indianapolis Int.	18h 31m layover 4h 42m - Las Vegas 3h 0m - Miami	Allegiant Air	G4451 NK202 NK199

Show all tickets

*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on May 09, 2025

Flight Schedule Des Moines (Iowa) to Indianapolis (Indiana)

Full flight schedule will help you in detecting at what time planes fly from Des Moines to Indianapolis. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
06:00 — 22:15	06:00 — 07:04 UA497 United Airlines Des Moines — Denver 10h 45m stop 17:49 — 22:15 UA1199 United Airlines Denver — Indianapolis	15h 15m including layover	Find flight from$346
07:00 — 18:46	07:00 — 10:48 G4431 Allegiant Air Des Moines — Tampa 5h 32m stop 16:20 — 18:46 NK150 Spirit Airlines Tampa — Indianapolis	10h 46m including layover	Find flight from$139
07:30 — 20:23	07:30 — 11:29 G4453 Allegiant Air Des Moines — Punta Gorda 6h 23m stop 17:52 — 20:23 G4619 Allegiant Air Punta Gorda — Indianapolis	11h 53m including layover	Find flight from$292
08:57 — 20:31	08:57 — 12:37 G41341 Allegiant Air Des Moines — Sanford 5h 37m stop 18:14 — 20:31 G42848 Allegiant Air Sanford — Indianapolis	10h 34m including layover	Find flight from$222
08:57 — 19:01	08:57 — 12:37 G41341 Allegiant Air Des Moines — Orlando 3h 51m stop 16:28 — 19:01 NK707 Spirit Airlines Orlando — Indianapolis	9h 4m including layover	Find flight from$235
09:00 — 20:03	09:00 — 12:50 G4464 Allegiant Air Des Moines — Sanford 4h 55m stop 17:45 — 20:03 G42245 Allegiant Air Sanford — Indianapolis	10h 3m including layover	Find flight from$226
09:00 — 20:03	09:00 — 12:50 G4464 Allegiant Air Des Moines — Sanford 4h 55m stop 17:45 — 20:03 G4629 Allegiant Air Sanford — Indianapolis	10h 3m including layover	Find flight from$297
11:35 — 16:50	11:25 — 12:53 UA2306 United Airlines Des Moines — Chicago 1h 25m stop 15:35 — 17:51 UA3657 United Airlines Chicago — Indianapolis	4h 15m including layover	Find flight from$237
11:35 — 18:10	11:35 — 13:10 UA2306 United Airlines Des Moines — Chicago 2h 45m stop 15:55 — 18:10 UA3690 United Airlines Chicago — Indianapolis	5h 35m including layover	Find flight from$237
13:45 — 14:34 +1 day	13:45 — 14:51 UA5669 United Airlines Des Moines — Denver 19h 17m stop 10:08 — 14:34 UA2255 United Airlines Denver — Indianapolis	23h 49m including layover	Find flight from$381
13:45 — 17:51 +1 day	13:45 — 14:51 UA5669 United Airlines Des Moines — Denver 22h 34m stop 13:25 — 17:51 UA513 United Airlines Denver — Indianapolis	27h 6m including layover	Find flight from$381
15:27 — 20:05	15:27 — 17:05 UA3457 United Airlines Des Moines — Chicago 45m stop 17:50 — 20:05 UA3628 United Airlines Chicago — Indianapolis	3h 38m including layover	Find flight from$237
15:27 — 22:05	15:27 — 17:05 UA3457 United Airlines Des Moines — Chicago 2h 47m stop 19:52 — 22:05 UA3707 United Airlines Chicago — Indianapolis	5h 38m including layover	Find flight from$237
17:10 — 17:51 +1 day	17:10 — 18:19 UA1781 United Airlines Des Moines — Denver 19h 6m stop 13:25 — 17:51 UA513 United Airlines Denver — Indianapolis	23h 41m including layover	Find flight from$362
17:13 — 14:35 +1 day	17:10 — 18:19 UA1781 United Airlines Des Moines — Denver 15h 47m stop 10:08 — 14:34 UA2255 United Airlines Denver — Indianapolis	20h 22m including layover	Find flight from$315
18:45 — 23:30	18:45 — 20:22 UA5286 United Airlines Des Moines — Chicago 55m stop 21:17 — 23:30 UA3650 United Airlines Chicago — Indianapolis	3h 45m including layover	Find flight from$237
18:54 — 23:14	18:54 — 20:25 UA3433 United Airlines Des Moines — Chicago 45m stop 21:10 — 23:14 UA3650 United Airlines Chicago — Indianapolis	3h 20m including layover	Find flight from$236
21:21 — 10:21 +1 day	18:51 — 19:57 F91677 Frontier Airlines Des Moines — Denver 7h 27m stop 11:00 — 15:29 F92348 Frontier Airlines Denver — Indianapolis	12h including layover	Find flight from$67

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on May 9, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Des Moines to Indianapolis depends on and how to choose the most interesting flight option for you.

Distance between Des Moines and Indianapolis is 652 miles. Time difference between the cities is 1h. Airplanes depart 05:45 to 21:21 from 1 Des Moines airport and arrive 05:45 to 21:21 to 1 Indianapolis airport. Average flight time is 10h 43m.

The fastest flight 3h 15m
Average flight time 10h 43m
The earliest flight 05:45
The latest flight 21:21
Distance 406 ml

The cheapest months to travel to Indianapolis are november (from 67 $), february (from 80 $), december (from 139 $).

The most expensive months are january (from 237 $), december (from 139 $), february (from 80 $).

What is the lowest airfare Des Moines to Indianapolis?

The cheapest plane ticket found by our users is $67. This airfare is for economy class on one-way F91677 flight by Frontier Airlines for February 21, 2025 which leaves Des Moines International Airport in Des Moines at 21:21 am and arrives at Indianapolis Indianapolis Int. at 10:21.

Economy class

$67

Find

Business class

Find

First class

Find

Popular Airlines on the Route

The flight Des Moines — Indianapolis is served by 3 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 2 departures per week at the price of from $ 67 . And the most expensive tickets are offered by United Airlines airline - from $ 831.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 144 flights with layovers on the route. The fastest connecting flight is UA1807 by United Airlines takes 3h 15m and the cheapest is F91677 by Frontier Airlines for $67.

F9 - Frontier Airlines

from $67

Find
UA - United Airlines

from $236

Find
G4 - Allegiant Air

from $139

Find

See more connecting flights

Airports

You can fly from Des Moines to Indianapolis from 1 airports (Des Moines International Airport).

Des Moines airports

Des Moines International Airport-DSM

from $67
Find

Indianapolis airports

Indianapolis Int.-IND

Find

Airplanes

There are flights to Indianapolis from Des Moines by 3 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Des Moines

You may also consider searching for discounted plane tickets to some other popular places from Des Moines within United States.

Des Moines — Las Vegas

from $55

Find
Des Moines — Phoenix

from $71

Find
Des Moines — Dallas

from $73

Find
Des Moines — Austin

from $78

Find
Des Moines — Seattle

from $53

Find
Des Moines — Atlanta

from $58

Find
Des Moines — Miami

from $65

Find
Des Moines — Denver

from $54

Find
Des Moines — New Orleans

from $56

Find
Des Moines — San Diego

from $58

Find

Top International Destinations from Des Moines

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Des Moines — Cancun

from $77

Find
Des Moines — London

from $70

Find

How to book a plane ticket yourself?

Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
To find a plane ticket, please select dates.