Cheap Flights from Myrtle Beach, SC to Cleveland, OH from $45

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On Cheapflightsplus.com you will find 4 direct and 82 connecting flights from Myrtle Beach to Cleveland. You can compare airfare deals from 5 airlines and multiple travel sites from $45, book and save on cheap plane tickets and last minute offers. Also check out MYR-CLE flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Myrtle Beach to Cleveland Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $45 (one-way), $77 (round-trip).

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Best Flights from Myrtle Beach to Cleveland Today

Take a look at the list of non stop flights and flights with layovers from Myrtle Beach to Cleveland with the lowest price of $45. The fastest direct flight takes 1h 44m and the fastest connecting – 4h 14m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $45 Find flight	13:24 Myrtle Beach AFB	15:08 Cleveland Cleveland Hopkins	1h 44m	Spirit Airlines	NK1807
from $48 Find flight	15:50 Myrtle Beach AFB	17:41 Cleveland Cleveland Hopkins	1h 51m	Frontier Airlines	F94118
from $66 Find flight	12:36 Myrtle Beach AFB	14:22 Cleveland Cleveland Hopkins	1h 46m	Spirit Airlines	NK3024
from $66 Find flight	17:32 Myrtle Beach AFB	19:18 Cleveland Cleveland Hopkins	1h 46m	Spirit Airlines	NK2648
from $92 Find flight	06:14 Myrtle Beach AFB	11:32 Cleveland Cleveland Hopkins	5h 18m layover 0h 42m - Miami	Spirit Airlines	NK1491 NK1710
from $113 Find flight	05:00 Myrtle Beach AFB	00:19+1 день Cleveland Cleveland Hopkins	19h 19m layover 14h 38m - Miami	Spirit Airlines	NK3646 NK1220
from $114 Find flight	06:09 Myrtle Beach AFB	11:55 Cleveland Cleveland Hopkins	5h 46m layover 1h 9m - Miami	Spirit Airlines	NK2656 NK2219
from $144 Find flight	06:10 Myrtle Beach AFB	09:49+1 день Cleveland Cleveland Hopkins	27h 39m layover 23h 48m - Orlando	Spirit Airlines	NK2644 NK1134
from $146 Find flight	16:50 Myrtle Beach AFB	22:00 Cleveland Cleveland Hopkins	5h 10m layover 1h 15m - Chicago	United Airlines	UA1580 UA1708
from $147 Find flight	17:16 Myrtle Beach AFB	21:42 Cleveland Cleveland Hopkins	4h 26m layover 0h 48m - Newark	United Airlines	UA1555 UA2398
from $147 Find flight	11:28 Myrtle Beach AFB	16:02 Cleveland Cleveland Hopkins	4h 34m layover 1h 8m - Newark	United Airlines	UA2630 UA2335
from $147 Find flight	16:45 Myrtle Beach AFB	22:04 Cleveland Cleveland Hopkins	5h 19m layover 1h 21m - Chicago	United Airlines	UA444 UA1641
from $147 Find flight	11:28 Myrtle Beach AFB	17:49 Cleveland Cleveland Hopkins	6h 21m layover 2h 49m - Newark	United Airlines	UA2630 UA1353
from $147 Find flight	16:45 Myrtle Beach AFB	23:59 Cleveland Cleveland Hopkins	7h 14m layover 3h 17m - Chicago	United Airlines	UA444 UA2347
from $138 Find flight	17:06 Myrtle Beach AFB	17:20+1 день Cleveland Cleveland Hopkins	24h 14m layover 2h 55m - Akron 16h 43m - Nashville	Allegiant Air	G42783 G41958 NK2033
from $144 Find flight	07:30 Myrtle Beach AFB	00:19+1 день Cleveland Cleveland Hopkins	16h 49m layover 2h 40m - Pittsburgh 7h 8m - Miami	Spirit Airlines	NK3182 NK1677 NK1220

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on June 28, 2025

Flight Schedule Myrtle Beach (South Carolina) to Cleveland (Ohio)

Full flight schedule will help you in detecting at what time planes fly from Myrtle Beach to Cleveland. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
12:36 — 14:22	12:36 — 14:22 NK3024 Spirit Airlines Myrtle Beach — Cleveland	1h 46m	Find flight from$66
13:24 — 15:08	13:24 — 15:08 NK1807 Spirit Airlines Myrtle Beach — Cleveland	1h 44m	Find flight from$45
15:50 — 17:41	15:50 — 17:41 F94118 Frontier Airlines Myrtle Beach — Cleveland	1h 51m	Find flight from$48
17:32 — 19:18	17:32 — 19:18 NK2648 Spirit Airlines Myrtle Beach — Cleveland	1h 46m	Find flight from$66
05:00 — 00:19 +1 day	05:00 — 06:52 NK3646 Spirit Airlines Myrtle Beach — Miami 14h 38m stop 21:30 — 00:19 NK1220 Spirit Airlines Miami — Cleveland	19h 19m including layover	Find flight from$113
06:09 — 11:55	06:09 — 08:00 NK2656 Spirit Airlines Myrtle Beach — Miami 1h 9m stop 09:09 — 11:55 NK2219 Spirit Airlines Miami — Cleveland	5h 46m including layover	Find flight from$114
06:14 — 11:32	06:14 — 08:05 NK1491 Spirit Airlines Myrtle Beach — Miami 42m stop 08:47 — 11:32 NK1710 Spirit Airlines Miami — Cleveland	5h 18m including layover	Find flight from$92
10:58 — 16:39	10:58 — 13:04 UA2630 United Airlines Myrtle Beach — Newark 1h 49m stop 14:53 — 16:39 UA3503 United Airlines Newark — Cleveland	5h 41m including layover	Find flight from$154
11:28 — 16:02	11:28 — 13:21 UA2630 United Airlines Myrtle Beach — Newark 1h 8m stop 14:30 — 16:03 UA2335 United Airlines Newark — Cleveland	4h 34m including layover	Find flight from$147
11:28 — 17:49	10:58 — 13:04 UA2630 United Airlines Myrtle Beach — Newark 2h 49m stop 16:15 — 17:55 UA1353 United Airlines Newark — Cleveland	6h 21m including layover	Find flight from$147
14:47 — 19:01	14:47 — 16:21 UA6194 United Airlines Myrtle Beach — Washington D.C. 1h 14m stop 17:35 — 19:01 UA2241 United Airlines Washington D.C. — Cleveland	4h 14m including layover	Find flight from$216
16:45 — 22:04	16:45 — 18:14 UA444 United Airlines Myrtle Beach — Chicago 1h 21m stop 19:35 — 22:04 UA1641 United Airlines Chicago — Cleveland	5h 19m including layover	Find flight from$147
16:50 — 22:00	16:50 — 18:20 UA1580 United Airlines Myrtle Beach — Chicago 1h 15m stop 19:35 — 22:00 UA1708 United Airlines Chicago — Cleveland	5h 10m including layover	Find flight from$146
05:00 — 19:00 +1 day	05:00 — 06:52 NK3646 Spirit Airlines Myrtle Beach — Miami 13h 42m stop 20:34 — 21:55 NK653 Spirit Airlines Miami — Nashville 18h 40m stop 16:35 — 19:00 NK2033 Spirit Airlines Nashville — Cleveland	38h including layover	Find flight from$192
07:30 — 00:19 +1 day	07:30 — 09:01 NK3182 Spirit Airlines Myrtle Beach — Pittsburgh 2h 40m stop 11:41 — 14:22 NK1677 Spirit Airlines Pittsburgh — Miami 7h 8m stop 21:30 — 00:19 NK1220 Spirit Airlines Miami — Cleveland	16h 49m including layover	Find flight from$144
07:30 — 00:19 +2 days	07:30 — 09:01 NK3182 Spirit Airlines Myrtle Beach — Pittsburgh 21h 29m stop 06:30 — 09:14 NK1675 Spirit Airlines Pittsburgh — Miami 12h 16m stop 21:30 — 00:19 NK1220 Spirit Airlines Miami — Cleveland	40h 49m including layover	Find flight from$225
08:34 — 00:19 +1 day	08:34 — 10:40 NK893 Spirit Airlines Myrtle Beach — Boston 5h 35m stop 11:56 — 15:17 NK2887 Spirit Airlines Boston — Miami 1h 51m stop 21:30 — 00:19 NK1220 Spirit Airlines Miami — Cleveland	15h 45m including layover	Find flight from$174
09:50 — 11:55 +1 day	09:50 — 11:28 G42051 Allegiant Air Myrtle Beach — Covington 3h 54m stop 15:22 — 17:51 G4495 Allegiant Air Covington — Miami 15h 18m stop 09:09 — 11:55 NK2219 Spirit Airlines Miami — Cleveland	26h 5m including layover	Find flight from$187
10:33 — 00:19 +1 day	10:33 — 12:23 NK3020 Spirit Airlines Myrtle Beach — Newark 4h 50m stop 17:13 — 20:20 NK672 Spirit Airlines Newark — Miami 1h 10m stop 21:30 — 00:19 NK1220 Spirit Airlines Miami — Cleveland	13h 46m including layover	Find flight from$147
12:37 — 11:55 +1 day	12:37 — 13:52 G42598 Allegiant Air Myrtle Beach — Huntington 6h 4m stop 19:56 — 22:18 G43471 Allegiant Air Huntington — Miami 10h 51m stop 09:09 — 11:55 NK2219 Spirit Airlines Miami — Cleveland	23h 18m including layover	Find flight from$157
13:11 — 11:55 +1 day	13:11 — 14:46 G41254 Allegiant Air Myrtle Beach — Louisville 14h 17m stop 05:03 — 07:25 NK2716 Spirit Airlines Louisville — Miami 1h 44m stop 09:09 — 11:55 NK2219 Spirit Airlines Miami — Cleveland	22h 44m including layover	Find flight from$216
15:29 — 11:55 +1 day	15:29 — 17:21 G4211 Allegiant Air Myrtle Beach — Newburgh 2h 35m stop 19:56 — 23:21 G4523 Allegiant Air Newburgh — Miami 9h 48m stop 09:09 — 11:55 NK2219 Spirit Airlines Miami — Cleveland	20h 26m including layover	Find flight from$168
17:06 — 17:20 +1 day	17:06 — 18:46 G42783 Allegiant Air Myrtle Beach — Akron 2h 55m stop 21:41 — 22:12 G41958 Allegiant Air Akron — Nashville 16h 43m stop 14:55 — 17:20 NK2033 Spirit Airlines Nashville — Cleveland	24h 14m including layover	Find flight from$138
19:30 — 17:20 +1 day	19:30 — 21:00 G42751 Allegiant Air Myrtle Beach — Pittsburgh 15h 21m stop 12:21 — 12:55 G42731 Allegiant Air Pittsburgh — Nashville 2h stop 14:55 — 17:20 NK2033 Spirit Airlines Nashville — Cleveland	21h 50m including layover	Find flight from$147
20:24 — 17:22 +1 day	20:24 — 21:50 NK2089 Spirit Airlines Myrtle Beach — Orlando 52m stop 22:42 — 23:45 NK2242 Spirit Airlines Orlando — Nashville 15h 10m stop 14:55 — 17:22 NK2033 Spirit Airlines Nashville — Cleveland	20h 58m including layover	Find flight from$217
21:20 — 11:55 +1 day	20:14 — 22:19 NK2475 Spirit Airlines Myrtle Beach — Detroit 5h 35m stop 05:00 — 08:04 NK2007 Spirit Airlines Detroit — Miami 1h 5m stop 09:09 — 11:55 NK2219 Spirit Airlines Miami — Cleveland	14h 35m including layover	Find flight from$169

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on June 28, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Myrtle Beach to Cleveland depends on and how to choose the most interesting flight option for you.

Distance between Myrtle Beach and Cleveland is 897 miles. Time difference between the cities is 0h. Airplanes depart 05:00 to 21:20 from 2 Myrtle Beach airports and arrive 05:00 to 21:20 to 3 Cleveland airports. Average flight time is 1h 46m.

The fastest flight 1h 44m
Average flight time 1h 46m
The earliest flight 05:00
The latest flight 21:20
Distance 558 ml

The cheapest months to travel to Cleveland are july (from 61 $), august (from 88 $), september (from 93 $).

What is the lowest airfare Myrtle Beach to Cleveland?

The cheapest plane ticket found by our users is $45. This airfare is for economy class on one-way NK1807 flight by Spirit Airlines for July 14, 2025 which leaves AFB in Myrtle Beach at 13:24 am and arrives at Cleveland Cleveland Hopkins at 15:08.

Economy class

$45

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Business class

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First class

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Popular Airlines on the Route

The flight Myrtle Beach — Cleveland is served by 5 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 1 departures per week at the price of from $ 48 . And the most expensive tickets are offered by United Airlines airline - from $ 1054.

Direct flights

There are 4 nonstop flights on the route. The fastest direct flight is NK1807 by Spirit Airlines takes 1h 44m and the cheapest is NK1807 by Spirit Airlines for $45.

F9 - Frontier Airlines

from $48

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NK - Spirit Airlines

from $45

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Connecting Flights

There are 82 flights with layovers on the route. The fastest connecting flight is UA6194 by United Airlines takes 4h 14m and the cheapest is NK1807 by Spirit Airlines for $92.

MX - Mexicana

from $200

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UA - United Airlines

from $146

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NK - Spirit Airlines

from $92

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G4 - Allegiant Air

from $138

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Airports

You can fly from Myrtle Beach to Cleveland from 2 airports (AFB, Grand Strand Airport).

Myrtle Beach airports

AFB-MYR

from $45
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Grand Strand Airport-CRE

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Cleveland airports

Cleveland Hopkins-CLE

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Burke Lakefront Airport-BKL

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Cuyahoga County-CGF

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Airplanes

There are flights to Cleveland from Myrtle Beach by 5 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Myrtle Beach

You may also consider searching for discounted plane tickets to some other popular places from Myrtle Beach within United States.

Myrtle Beach — Orlando

from $66

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Myrtle Beach — Boston

from $59

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Myrtle Beach — Pittsburgh

from $56

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Myrtle Beach — Miami

from $66

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Myrtle Beach — Atlanta

from $59

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Myrtle Beach — Nashville

from $57

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Myrtle Beach — Las Vegas

from $60

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Myrtle Beach — Chicago

from $69

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Myrtle Beach — Detroit

from $74

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Myrtle Beach — Tampa

from $79

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Top International Destinations from Myrtle Beach

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Myrtle Beach — Toronto

from $57

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How to book a plane ticket yourself?

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That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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