Cheap Flights from Knoxville, TN to San Francisco, CA from $127
On Cheapflightsplus.com you will find 183 connecting flights from Knoxville to San Francisco. You can compare airfare deals from 4 airlines and multiple travel sites from $127, book and save on cheap plane tickets and last minute offers. Also check out TYS-SFO flight schedule to find best flight time, convenient departure and arrival airports.
Flight Information
Below we will explain in detail what the flights cost on the destination from Knoxville to San Francisco depends on and how to choose the most interesting flight option for you.
Distance between Knoxville and San Francisco is 3403 miles. Time difference between the cities is 3h. Airplanes depart 05:45 to 21:30 from 1 Knoxville airport and arrive 05:45 to 21:30 to 3 San Francisco airports. Average flight time is 14h 52m.
- The fastest flight 7h 9m
- Average flight time 14h 52m
- The earliest flight 05:45
- The latest flight 21:30
- Distance 2115 ml
Best Flights from Knoxville to San Francisco Today
| Price | Departure | Arrival | Flight Duration | Airline | Flight |
|---|---|---|---|---|---|
| from $127 | 11:01 Knoxville Mc Ghee Tyson | 22:53 San Francisco San Francisco | 14h 52m layover 8h 26m - Minneapolis | Allegiant Air | G43064 SY397 |
| from $176 | 17:25 Knoxville Mc Ghee Tyson | 00:19+1 день San Francisco San Francisco | 9h 54m layover 3h 49m - Denver | Frontier Airlines | F94369 F93439 |
| from $187 | 12:45 Knoxville Mc Ghee Tyson | 22:53+1 день San Francisco San Francisco | 37h 8m layover 6h 7m - Washington D.C. 22h 40m - Minneapolis | Allegiant Air | G41397 SY1686 SY397 |
| from $218 | 15:54 Knoxville Mc Ghee Tyson | 22:53+1 день San Francisco San Francisco | 33h 59m layover 17h 17m - Denver 7h 34m - Minneapolis | Allegiant Air | G43029 SY652 SY397 |
The cheapest months to travel to San Francisco are july (from 127 $), august (from 131 $), october (from 240 $).
The most expensive months are september (from 240 $), october (from 240 $), august (from 131 $).
What is the lowest airfare Knoxville to San Francisco?
The cheapest plane ticket found by our users is $127. This airfare is for economy class on one-way G43064 flight by Allegiant Air for August 8, 2025 which leaves Mc Ghee Tyson in Knoxville at 11:01 am and arrives at San Francisco San Francisco at 22:53.
Flight Schedule Knoxville (Tennessee) to San Francisco (California)
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Popular Airlines on the Route
The flight Knoxville — San Francisco is served by 4 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 2 departures per week at the price of from $ 337 . And the most expensive tickets are offered by United Airlines airline - from $ 995.
Direct flights
There’re no direct flights on this route. Try flights with stops.
Connecting Flights
There are 183 flights with layovers on the route. The fastest connecting flight is UA5673 by United Airlines takes 7h 9m and the cheapest is G43064 by Allegiant Air for $127.
- AS - Alaska Airlinesfrom $337Find
- F9 - Frontier Airlinesfrom $176Find
- UA - United Airlinesfrom $296Find
- G4 - Allegiant Airfrom $127Find
Airports
You can fly from Knoxville to San Francisco from 1 airports (Mc Ghee Tyson).
Knoxville airports
- Mc Ghee Tyson-TYSfrom $127Find
San Francisco airports
- San Francisco-SFOFind
- Embarkadero-EMBFind
- China Basin Heliport-JCCFind
Airplanes
There are flights to San Francisco from Knoxville by 4 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Knoxville
You may also consider searching for discounted plane tickets to some other popular places from Knoxville within United States.
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Top International Destinations from Knoxville
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
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How to book a plane ticket yourself?
- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
- Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
- Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
- Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
- That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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