Cheap Flights from Knoxville, TN to Key West, FL from $271

One way Round trip

Adults

Children under 12

Infants under 2 without place

Economy

Business

First

done

Return flight: Key West – Knoxville

Page navigation

Price Calendar Cheap Flights Flights Schedule

On Cheapflightsplus.com you will find 36 connecting flights from Knoxville to Key West. You can compare airfare deals from 1 airlines and multiple travel sites from $271, book and save on cheap plane tickets and last minute offers. Also check out TYS-EYW flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Knoxville to Key West Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $271 (one-way), $465 (round-trip).

Direct flights

Check to choose departure date Check to choose departure date

Check prices for return flight

Find flights

Best Flights from Knoxville to Key West Today

Take a look at the list of non stop flights and flights with layovers from Knoxville to Key West with the lowest price of $271. Take a look at the list of flights with layovers from Knoxville to Key West from $271. There’re no direct flights. The fastest connecting flight – 5h 54m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $271 Find flight	09:15 Knoxville Mc Ghee Tyson	16:03 Key West Key West Int.	6h 48m layover 1h 10m - Houston	United Airlines	UA4841 UA6200
from $271 Find flight	07:05 Knoxville Mc Ghee Tyson	16:03 Key West Key West Int.	8h 58m layover 3h 20m - Houston	United Airlines	UA4913 UA6200
from $313 Find flight	05:45 Knoxville Mc Ghee Tyson	11:39 Key West Key West Int.	5h 54m layover 0h 54m - Washington D.C.	United Airlines	UA4311 UA6217
from $361 Find flight	07:00 Knoxville Mc Ghee Tyson	15:01 Key West Key West Int.	8h 1m layover 2h 54m - Chicago	United Airlines	UA776 UA325
from $436 Find flight	17:47 Knoxville Mc Ghee Tyson	14:50+1 день Key West Key West Int.	21h 3m layover 15h 46m - Chicago	United Airlines	UA5305 UA2070
from $436 Find flight	13:55 Knoxville Mc Ghee Tyson	14:50+1 день Key West Key West Int.	24h 55m layover 19h 45m - Chicago	United Airlines	UA5844 UA2070
from $451 Find flight	14:35 Knoxville Mc Ghee Tyson	11:39+1 день Key West Key West Int.	21h 4m layover 16h 5m - Washington D.C.	United Airlines	UA4848 UA6217
from $451 Find flight	09:35 Knoxville Mc Ghee Tyson	11:39+1 день Key West Key West Int.	26h 4m layover 21h 4m - Washington D.C.	United Airlines	UA4325 UA6217
from $457 Find flight	09:55 Knoxville Mc Ghee Tyson	11:21+1 день Key West Key West Int.	25h 26m layover 20h 43m - Washington D.C.	United Airlines	UA4325 UA1620
from $462 Find flight	07:00 Knoxville Mc Ghee Tyson	14:50 Key West Key West Int.	7h 50m layover 2h 34m - Chicago	United Airlines	UA1677 UA2070
from $468 Find flight	07:00 Knoxville Mc Ghee Tyson	15:11 Key West Key West Int.	8h 11m layover 2h 56m - Chicago	United Airlines	UA2046 UA2070
from $337 Find flight	05:45 Knoxville Mc Ghee Tyson	18:55 Key West Key West Int.	13h 10m layover 0h 52m - Washington D.C. 6h 38m - Miami	United Airlines	UA4311 UA1825 UA3094
from $347 Find flight	10:35 Knoxville Mc Ghee Tyson	09:15+1 день Key West Key West Int.	22h 40m layover 2h 15m - Houston 14h 9m - Tampa	United Airlines	UA4302 UA1478 UA3135
from $371 Find flight	09:55 Knoxville Mc Ghee Tyson	18:55 Key West Key West Int.	9h 0m layover 1h 33m - Washington D.C. 1h 50m - Miami	United Airlines	UA4325 UA528 UA3094
from $404 Find flight	09:25 Knoxville Mc Ghee Tyson	09:15+1 день Key West Key West Int.	23h 50m layover 1h 19m - Houston 16h 18m - Tampa	United Airlines	UA4841 UA1501 UA3135
from $465 Find flight	07:00 Knoxville Mc Ghee Tyson	18:55 Key West Key West Int.	11h 55m layover 1h 30m - Houston 4h 2m - Miami	United Airlines	UA4913 UA1083 UA3094

Show all tickets

*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on November 18, 2024

Flight Schedule Knoxville (Tennessee) to Key West (Florida)

Full flight schedule will help you in detecting at what time planes fly from Knoxville to Key West. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
05:45 — 11:39	05:45 — 07:31 UA4311 United Airlines Knoxville — Washington D.C. 54m stop 08:25 — 11:39 UA6217 United Airlines Washington D.C. — Key West	5h 54m including layover	Find flight from$313
07:00 — 15:01	07:00 — 08:01 UA776 United Airlines Knoxville — Chicago 2h 54m stop 10:55 — 15:01 UA325 United Airlines Chicago — Key West	8h 1m including layover	Find flight from$361
07:05 — 16:03	06:45 — 08:36 UA4913 United Airlines Knoxville — Houston 3h 20m stop 12:09 — 16:01 UA6200 United Airlines Houston — Key West	8h 58m including layover	Find flight from$271
09:15 — 16:03	09:10 — 11:01 UA4841 United Airlines Knoxville — Houston 1h 10m stop 12:09 — 16:01 UA6200 United Airlines Houston — Key West	6h 48m including layover	Find flight from$271
13:55 — 14:50 +1 day	13:55 — 14:51 UA5844 United Airlines Knoxville — Chicago 19h 45m stop 10:36 — 14:50 UA2070 United Airlines Chicago — Key West	24h 55m including layover	Find flight from$436
14:35 — 11:39 +1 day	14:35 — 16:20 UA4848 United Airlines Knoxville — Washington D.C. 16h 5m stop 08:25 — 11:39 UA6217 United Airlines Washington D.C. — Key West	21h 4m including layover	Find flight from$451
14:40 — 11:21 +1 day	14:40 — 16:21 UA4848 United Airlines Knoxville — Washington D.C. 15h 59m stop 08:20 — 11:21 UA1620 United Airlines Washington D.C. — Key West	20h 41m including layover	Find flight from$499
17:47 — 14:50 +1 day	17:47 — 18:50 UA5305 United Airlines Knoxville — Chicago 15h 46m stop 10:36 — 14:50 UA2070 United Airlines Chicago — Key West	21h 3m including layover	Find flight from$436
19:25 — 11:21 +1 day	19:25 — 21:07 UA4324 United Airlines Knoxville — Washington D.C. 11h 13m stop 08:20 — 11:21 UA1620 United Airlines Washington D.C. — Key West	15h 56m including layover	Find flight from$499
05:45 — 18:55	05:45 — 07:33 UA4311 United Airlines Knoxville — Washington D.C. 52m stop 08:25 — 11:12 UA1825 United Airlines Washington D.C. — Miami 6h 38m stop 17:50 — 18:55 UA3094 United Airlines Miami — Key West	13h 10m including layover	Find flight from$337
09:55 — 18:55	09:55 — 11:37 UA4325 United Airlines Knoxville — Washington D.C. 1h 33m stop 13:10 — 16:00 UA528 United Airlines Washington D.C. — Miami 1h 50m stop 17:50 — 18:55 UA3094 United Airlines Miami — Key West	9h including layover	Find flight from$371
10:35 — 09:15 +1 day	10:35 — 12:20 UA4302 United Airlines Knoxville — Houston 2h 15m stop 14:35 — 17:51 UA1478 United Airlines Houston — Tampa 14h 9m stop 08:00 — 09:15 UA3135 United Airlines Tampa — Key West	22h 40m including layover	Find flight from$347
10:50 — 14:20 +1 day	10:50 — 11:54 UA5300 United Airlines Knoxville — Chicago 2h 1m stop 13:55 — 17:43 UA2855 United Airlines Chicago — Orlando 19h 12m stop 12:55 — 14:20 UA3071 United Airlines Orlando — Key West	27h 30m including layover	Find flight from$538
17:46 — 17:15 +1 day	17:46 — 18:55 UA5305 United Airlines Knoxville — Chicago 12h 35m stop 07:30 — 11:19 UA2326 United Airlines Chicago — Tampa 4h 41m stop 16:00 — 17:15 UA3137 United Airlines Tampa — Key West	23h 29m including layover	Find flight from$494

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on November 18, 2024

Flight Information

Below we will explain in detail what the flights cost on the destination from Knoxville to Key West depends on and how to choose the most interesting flight option for you.

Distance between Knoxville and Key West is 1270 miles. Time difference between the cities is 0h. Airplanes depart 05:45 to 19:25 from 1 Knoxville airport and arrive 05:45 to 19:25 to 2 Key West airports. Average flight time is 21h 52m.

The fastest flight 5h 54m
Average flight time 21h 52m
The earliest flight 05:45
The latest flight 19:25
Distance 790 ml

The cheapest months to travel to Key West are february (from 271 $), december (from 337 $), november (from 378 $).

What is the lowest airfare Knoxville to Key West?

The cheapest plane ticket found by our users is $271. This airfare is for economy class on one-way UA4841 flight by United Airlines for February 1, 2025 which leaves Mc Ghee Tyson in Knoxville at 09:15 am and arrives at Key West Key West Int. at 16:03.

Economy class

$271

Find

Business class

Find

First class

Find

Popular Airlines on the Route

The flight Knoxville — Key West is served by 1 regular airline . Most of the flights on this route are operated by United Airlines - 36 departures per week at the price of from $ 271 . And the most expensive tickets are offered by United Airlines airline - from $ 600.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 36 flights with layovers on the route. The fastest connecting flight is UA4311 by United Airlines takes 5h 54m and the cheapest is UA4841 by United Airlines for $271.

UA - United Airlines

from $271

Find

See more connecting flights

Airports

You can fly from Knoxville to Key West from 1 airports (Mc Ghee Tyson).

Knoxville airports

Mc Ghee Tyson-TYS

from $271
Find

Key West airports

NAS-NQX

Find
Key West Int.-EYW

Find

Airplanes

There are flights to Key West from Knoxville by 1 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Knoxville

You may also consider searching for discounted plane tickets to some other popular places from Knoxville within United States.

Knoxville — Tampa

from $80

Find
Knoxville — Houston

from $54

Find
Knoxville — New Orleans

from $56

Find
Knoxville — Orlando

from $73

Find
Knoxville — Chicago

from $76

Find
Knoxville — Boston

from $69

Find
Knoxville — San Francisco

from $78

Find
Knoxville — Las Vegas

from $74

Find
Knoxville — Key West

from $64

Find
Knoxville — Seattle

from $73

Find

Top International Destinations from Knoxville

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Knoxville — Cancun

from $69

Find
Knoxville — Panama City

from $61

Find
Knoxville — Manchester

from $64

Find

How to book a plane ticket yourself?

Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
To find a plane ticket, please select dates.