Cheap Flights from Knoxville, TN to Key West, FL from $181

Return flight: Key West – Knoxville
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On Cheapflightsplus.com you will find 7 connecting flights from Knoxville to Key West. You can compare airfare deals from 2 airlines and multiple travel sites from $181, book and save on cheap plane tickets and last minute offers. Also check out TYS-EYW flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Knoxville to Key West Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $181 (one-way), $310 (round-trip).
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Best Flights from Knoxville to Key West Today

Take a look at the list of non stop flights and flights with layovers from Knoxville to Key West with the lowest price of $181. Take a look at the list of flights with layovers from Knoxville to Key West from $181. There’re no direct flights. The fastest connecting flight – 6h 31m.
Price Departure Arrival Flight Duration Airline Flight
from $181
Find flight
07:30
Knoxville
Mc Ghee Tyson
 14:01
Key West
Key West Int.
 6h 31m
layover
3h 1m - Charlotte
 American Airlines
AA5072
AA4648
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on July 27, 2024
Full flight schedule will help you in detecting at what time planes fly from Knoxville to Key West. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
07:30 — 14:01
07:30 — 08:44 AA5072 American Airlines
Knoxville — Charlotte
3h 1m stop
11:45 — 14:01 AA4648 American Airlines
Charlotte — Key West
6h 31m
including layover
Find flight
from$181
14:55 — 11:40
+1 day
14:55 — 16:25 UA3864 United Airlines
Knoxville — Washington D.C.
1h 20m stop
17:45 — 20:18 UA2232 United Airlines
Washington D.C. — Miami
14h 17m stop
10:35 — 11:40 UA3093 United Airlines
Miami — Key West
20h 45m
including layover
Find flight
from$313
18:20 — 11:19
+1 day
18:20 — 20:10 AA5046 American Airlines
Knoxville — Washington D.C.
10h 49m stop
06:59 — 09:43 AA391 American Airlines
Washington D.C. — Miami
42m stop
10:25 — 11:19 AA4558 American Airlines
Miami — Key West
16h 59m
including layover
Find flight
from$315
18:20 — 11:19
+1 day
18:20 — 20:10 AA5046 American Airlines
Knoxville — Washington D.C.
9h 50m stop
06:00 — 08:41 AA1178 American Airlines
Washington D.C. — Miami
1h 44m stop
10:25 — 11:19 AA4558 American Airlines
Miami — Key West
16h 59m
including layover
Find flight
from$315
18:20 — 12:52
+1 day
18:20 — 20:10 AA5046 American Airlines
Knoxville — Washington D.C.
9h 50m stop
06:00 — 08:41 AA1178 American Airlines
Washington D.C. — Miami
3h 19m stop
12:00 — 12:52 AA4396 American Airlines
Miami — Key West
18h 32m
including layover
Find flight
from$315
18:20 — 12:52
+1 day
18:20 — 20:10 AA5046 American Airlines
Knoxville — Washington D.C.
11h 49m stop
07:59 — 10:42 AA1340 American Airlines
Washington D.C. — Miami
1h 18m stop
12:00 — 12:52 AA4396 American Airlines
Miami — Key West
18h 32m
including layover
Find flight
from$315
18:20 — 12:52
+1 day
18:20 — 20:10 AA5046 American Airlines
Knoxville — Washington D.C.
10h 49m stop
06:59 — 09:43 AA391 American Airlines
Washington D.C. — Miami
2h 17m stop
12:00 — 12:52 AA4396 American Airlines
Miami — Key West
18h 32m
including layover
Find flight
from$315
*Departure and arrival times - local. Updated on July 27, 2024

Flight Information

Below we will explain in detail what the flights cost on the destination from Knoxville to Key West depends on and how to choose the most interesting flight option for you.

Distance between Knoxville and Key West is 1270 miles. Time difference between the cities is 0h. Airplanes depart 07:30 to 18:20 from 1 Knoxville airport and arrive 07:30 to 18:20 to 2 Key West airports. Average flight time is 18h 32m.

  • The fastest flight 6h 31m
  • Average flight time 18h 32m
  • The earliest flight 07:30
  • The latest flight 18:20
  • Distance 790 ml

What is the lowest airfare Knoxville to Key West?

The cheapest plane ticket found by our users is $181. This airfare is for economy class on one-way AA5072 flight by American Airlines for August 22, 2020 which leaves Mc Ghee Tyson in Knoxville at 07:30 am and arrives at Key West Key West Int. at 14:01.

Economy class
$181
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Business class
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First class
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Popular Airlines on the Route

The flight Knoxville — Key West is served by 2 regular airlines . Most of the flights on this route are operated by American Airlines - 6 departures per week at the price of from $ 181 . And the most expensive tickets are offered by American Airlines airline - from $ 315.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 7 flights with layovers on the route. The fastest connecting flight is AA5072 by American Airlines takes 6h 31m and the cheapest is AA5072 by American Airlines for $181.

  • AA - American Airlines
    from $181
    Find
  • UA - United Airlines
    from $313
    Find
See more connecting flights

Airports

You can fly from Knoxville to Key West from 1 airports (Mc Ghee Tyson).

Knoxville airports

  • Mc Ghee Tyson-TYS
    from $181
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Key West airports

  • NAS-NQX
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  • Key West Int.-EYW
    Find

Airplanes

There are flights to Key West from Knoxville by 2 airlines that use 1 aircraft brands. They range from huge modern airplanes to small-sized.

  • Canadair CRJ900
    from $181
    Find

Top Domestic Destinations from Knoxville

You may also consider searching for discounted plane tickets to some other popular places from Knoxville within United States.

Top International Destinations from Knoxville

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

All flights from Knoxville | All flights to Key West

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
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  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

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