Cheap Flights from Knoxville, TN to Key West, FL from $265

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On Cheapflightsplus.com you will find 14 connecting flights from Knoxville to Key West. You can compare airfare deals from 1 airlines and multiple travel sites from $265, book and save on cheap plane tickets and last minute offers. Also check out TYS-EYW flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Knoxville to Key West Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $265 (one-way), $454 (round-trip).

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Best Flights from Knoxville to Key West Today

Take a look at the list of non stop flights and flights with layovers from Knoxville to Key West with the lowest price of $265. Take a look at the list of flights with layovers from Knoxville to Key West from $265. There’re no direct flights. The fastest connecting flight – 5h 54m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $265 Find flight	09:15 Knoxville Mc Ghee Tyson	16:03 Key West Key West Int.	6h 48m layover 1h 10m - Houston	United Airlines	UA4841 UA6200
from $265 Find flight	07:05 Knoxville Mc Ghee Tyson	16:03 Key West Key West Int.	8h 58m layover 3h 20m - Houston	United Airlines	UA4913 UA6200
from $307 Find flight	05:45 Knoxville Mc Ghee Tyson	11:39 Key West Key West Int.	5h 54m layover 0h 54m - Washington D.C.	United Airlines	UA4311 UA6217
from $427 Find flight	17:47 Knoxville Mc Ghee Tyson	14:50+1 день Key West Key West Int.	21h 3m layover 15h 46m - Chicago	United Airlines	UA5305 UA2070
from $427 Find flight	13:55 Knoxville Mc Ghee Tyson	14:50+1 день Key West Key West Int.	24h 55m layover 19h 45m - Chicago	United Airlines	UA5844 UA2070
from $442 Find flight	14:35 Knoxville Mc Ghee Tyson	11:39+1 день Key West Key West Int.	21h 4m layover 16h 5m - Washington D.C.	United Airlines	UA4848 UA6217
from $442 Find flight	09:35 Knoxville Mc Ghee Tyson	11:39+1 день Key West Key West Int.	26h 4m layover 21h 4m - Washington D.C.	United Airlines	UA4325 UA6217
from $447 Find flight	09:55 Knoxville Mc Ghee Tyson	11:21+1 день Key West Key West Int.	25h 26m layover 20h 43m - Washington D.C.	United Airlines	UA4325 UA1620
from $453 Find flight	07:00 Knoxville Mc Ghee Tyson	14:50 Key West Key West Int.	7h 50m layover 2h 34m - Chicago	United Airlines	UA1677 UA2070
from $459 Find flight	07:00 Knoxville Mc Ghee Tyson	15:11 Key West Key West Int.	8h 11m layover 2h 56m - Chicago	United Airlines	UA2046 UA2070
from $488 Find flight	19:25 Knoxville Mc Ghee Tyson	11:21+1 день Key West Key West Int.	15h 56m layover 11h 13m - Washington D.C.	United Airlines	UA4324 UA1620
from $488 Find flight	14:40 Knoxville Mc Ghee Tyson	11:21+1 день Key West Key West Int.	20h 41m layover 15h 59m - Washington D.C.	United Airlines	UA4848 UA1620
from $339 Find flight	10:35 Knoxville Mc Ghee Tyson	09:15+1 день Key West Key West Int.	22h 40m layover 2h 15m - Houston 14h 9m - Tampa	United Airlines	UA4302 UA1478 UA3135
from $364 Find flight	09:55 Knoxville Mc Ghee Tyson	18:55 Key West Key West Int.	9h 0m layover 1h 33m - Washington D.C. 1h 50m - Miami	United Airlines	UA4325 UA528 UA3094

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on December 30, 2024

Flight Schedule Knoxville (Tennessee) to Key West (Florida)

Full flight schedule will help you in detecting at what time planes fly from Knoxville to Key West. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
05:45 — 11:39	05:45 — 07:31 UA4311 United Airlines Knoxville — Washington D.C. 54m stop 08:25 — 11:39 UA6217 United Airlines Washington D.C. — Key West	5h 54m including layover	Find flight from$307
07:00 — 14:50	07:00 — 08:02 UA1677 United Airlines Knoxville — Chicago 2h 34m stop 10:36 — 14:50 UA2070 United Airlines Chicago — Key West	7h 50m including layover	Find flight from$453
07:00 — 15:11	07:00 — 08:03 UA2046 United Airlines Knoxville — Chicago 2h 56m stop 10:59 — 15:11 UA2070 United Airlines Chicago — Key West	8h 11m including layover	Find flight from$459
07:05 — 16:03	06:45 — 08:36 UA4913 United Airlines Knoxville — Houston 3h 20m stop 12:09 — 16:01 UA6200 United Airlines Houston — Key West	8h 58m including layover	Find flight from$265
09:15 — 16:03	09:10 — 11:01 UA4841 United Airlines Knoxville — Houston 1h 10m stop 12:09 — 16:01 UA6200 United Airlines Houston — Key West	6h 48m including layover	Find flight from$265
09:35 — 11:39 +1 day	09:35 — 11:21 UA4325 United Airlines Knoxville — Washington D.C. 21h 4m stop 08:25 — 11:39 UA6217 United Airlines Washington D.C. — Key West	26h 4m including layover	Find flight from$442
09:55 — 11:21 +1 day	09:55 — 11:37 UA4325 United Airlines Knoxville — Washington D.C. 20h 43m stop 08:20 — 11:21 UA1620 United Airlines Washington D.C. — Key West	25h 26m including layover	Find flight from$447
13:55 — 14:50 +1 day	13:55 — 14:51 UA5844 United Airlines Knoxville — Chicago 19h 45m stop 10:36 — 14:50 UA2070 United Airlines Chicago — Key West	24h 55m including layover	Find flight from$427
14:35 — 11:39 +1 day	14:35 — 16:20 UA4848 United Airlines Knoxville — Washington D.C. 16h 5m stop 08:25 — 11:39 UA6217 United Airlines Washington D.C. — Key West	21h 4m including layover	Find flight from$442
14:40 — 11:21 +1 day	14:40 — 16:21 UA4848 United Airlines Knoxville — Washington D.C. 15h 59m stop 08:20 — 11:21 UA1620 United Airlines Washington D.C. — Key West	20h 41m including layover	Find flight from$488
17:47 — 14:50 +1 day	17:47 — 18:50 UA5305 United Airlines Knoxville — Chicago 15h 46m stop 10:36 — 14:50 UA2070 United Airlines Chicago — Key West	21h 3m including layover	Find flight from$427
19:25 — 11:21 +1 day	19:25 — 21:07 UA4324 United Airlines Knoxville — Washington D.C. 11h 13m stop 08:20 — 11:21 UA1620 United Airlines Washington D.C. — Key West	15h 56m including layover	Find flight from$488
09:55 — 18:55	09:55 — 11:37 UA4325 United Airlines Knoxville — Washington D.C. 1h 33m stop 13:10 — 16:00 UA528 United Airlines Washington D.C. — Miami 1h 50m stop 17:50 — 18:55 UA3094 United Airlines Miami — Key West	9h including layover	Find flight from$364
10:35 — 09:15 +1 day	10:35 — 12:20 UA4302 United Airlines Knoxville — Houston 2h 15m stop 14:35 — 17:51 UA1478 United Airlines Houston — Tampa 14h 9m stop 08:00 — 09:15 UA3135 United Airlines Tampa — Key West	22h 40m including layover	Find flight from$339

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on December 30, 2024

Flight Information

Below we will explain in detail what the flights cost on the destination from Knoxville to Key West depends on and how to choose the most interesting flight option for you.

Distance between Knoxville and Key West is 1270 miles. Time difference between the cities is 0h. Airplanes depart 05:45 to 19:25 from 1 Knoxville airport and arrive 05:45 to 19:25 to 2 Key West airports. Average flight time is 18h 19m.

The fastest flight 5h 54m
Average flight time 18h 19m
The earliest flight 05:45
The latest flight 19:25
Distance 790 ml

The cheapest months to travel to Key West are february (from 265 $).

What is the lowest airfare Knoxville to Key West?

The cheapest plane ticket found by our users is $265. This airfare is for economy class on one-way UA4841 flight by United Airlines for February 1, 2025 which leaves Mc Ghee Tyson in Knoxville at 09:15 am and arrives at Key West Key West Int. at 16:03.

Economy class

$265

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Business class

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First class

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Popular Airlines on the Route

The flight Knoxville — Key West is served by 1 regular airline . Most of the flights on this route are operated by United Airlines - 14 departures per week at the price of from $ 265 . And the most expensive tickets are offered by United Airlines airline - from $ 488.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 14 flights with layovers on the route. The fastest connecting flight is UA4311 by United Airlines takes 5h 54m and the cheapest is UA4841 by United Airlines for $265.

UA - United Airlines

from $265

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Airports

You can fly from Knoxville to Key West from 1 airports (Mc Ghee Tyson).

Knoxville airports

Mc Ghee Tyson-TYS

from $265
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Key West airports

NAS-NQX

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Key West Int.-EYW

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Airplanes

There are flights to Key West from Knoxville by 1 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Knoxville

You may also consider searching for discounted plane tickets to some other popular places from Knoxville within United States.

Knoxville — Tampa

from $80

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Knoxville — Houston

from $54

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Knoxville — New Orleans

from $56

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Knoxville — Orlando

from $73

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Knoxville — Chicago

from $76

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Knoxville — Boston

from $69

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Knoxville — San Francisco

from $78

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Knoxville — Las Vegas

from $74

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Knoxville — Key West

from $64

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Knoxville — Seattle

from $73

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Top International Destinations from Knoxville

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Knoxville — Cancun

from $69

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Knoxville — Panama City

from $61

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Knoxville — Manchester

from $64

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How to book a plane ticket yourself?

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