Cheap Flights from Santa Ana, CA to Chicago, IL from $66
On Cheapflightsplus.com you will find 17 direct and 279 connecting flights from Santa Ana to Chicago. You can compare airfare deals from 7 airlines and multiple travel sites from $66, book and save on cheap plane tickets and last minute offers. Also check out SNA-CHI flight schedule to find best flight time, convenient departure and arrival airports.
Flight Information
Below we will explain in detail what the flights cost on the destination from Santa Ana to Chicago depends on and how to choose the most interesting flight option for you.
Distance between Santa Ana and Chicago is 2792 miles. Time difference between the cities is 2h. Airplanes depart 06:45 to 21:15 from 3 Santa Ana airports and arrive 06:45 to 21:15 to 7 Chicago airports. Average flight time is 4h 11m.
- The fastest flight 4h 10m
- Average flight time 4h 11m
- The earliest flight 06:45
- The latest flight 21:15
- Distance 1735 ml
Best Flights from Santa Ana to Chicago Today
Price | Departure | Arrival | Flight Duration | Airline | Flight |
---|---|---|---|---|---|
from $223 | 15:07 Santa Ana John Wayne | 21:24 Chicago O'Hare International | 4h 17m | Alaska Airlines | AS4237 |
from $224 | 10:30 Santa Ana John Wayne | 16:41 Chicago O'Hare International | 4h 11m | United Airlines | UA2849 |
from $272 | 10:19 Santa Ana John Wayne | 16:30 Chicago O'Hare International | 4h 11m | Alaska Airlines | AS6068 |
from $66 | 12:01 Santa Ana John Wayne | 20:54 Chicago Midway | 6h 53m layover 1h 51m - Denver | Frontier Airlines | F94372 F92210 |
from $90 | 06:45 Santa Ana John Wayne | 14:16 Chicago O'Hare International | 5h 31m layover 0h 35m - Las Vegas | Spirit Airlines | NK870 NK187 |
The cheapest months to travel to Chicago are october (from 66 $), november (from 66 $), january (from 87 $).
The most expensive months are september (from 102 $), december (from 92 $), july (from 91 $).
What is the lowest airfare Santa Ana to Chicago?
The cheapest plane ticket found by our users is $66. This airfare is for economy class on one-way F94372 flight by Frontier Airlines for October 29, 2025 which leaves John Wayne in Santa Ana at 12:01 am and arrives at Chicago Midway at 20:54.
Flight Schedule Santa Ana (California) to Chicago (Illinois)
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Popular Airlines on the Route
The flight Santa Ana — Chicago is served by 7 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 55 departures per week at the price of from $ 127 . And the most expensive tickets are offered by United Airlines airline - from $ 622.
Direct flights
There are 17 nonstop flights on the route. The fastest direct flight is AS4336 by Alaska Airlines takes 4h 10m and the cheapest is F94372 by Frontier Airlines for $223.
- AS - Alaska Airlinesfrom $223Find
- UA - United Airlinesfrom $224Find
Connecting Flights
There are 279 flights with layovers on the route. The fastest connecting flight is NK870 by Spirit Airlines takes 5h 31m and the cheapest is F94372 by Frontier Airlines for $66.
- AS - Alaska Airlinesfrom $127Find
- F9 - Frontier Airlinesfrom $66Find
- HA - Hawaiian Airlinesfrom $119Find
- MX - Mexicanafrom $342Find
- UA - United Airlinesfrom $233Find
- NK - Spirit Airlinesfrom $90Find
- G4 - Allegiant Airfrom $183Find
Airports
You can fly from Santa Ana to Chicago from 3 airports (John Wayne, Santa Ana Heliport, Centerport Heliport).
Santa Ana airports
- John Wayne-SNAfrom $66Find
- Santa Ana Heliport-DNTFind
- Centerport Heliport-JOCFind
Chicago airports
- O'Hare International-ORDFind
- Midway-MDWFind
- Dupage County-DPAFind
- Chicago FSS-CHIFind
- Merrill C Meigs (closed)-CGXFind
- Pal-Waukee-PWKFind
- Chicago NAS-NOHFind
Airplanes
There are flights to Chicago from Santa Ana by 7 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Santa Ana
You may also consider searching for discounted plane tickets to some other popular places from Santa Ana within United States.
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Top International Destinations from Santa Ana
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
How to book a plane ticket yourself?

- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
- Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
- Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
- Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
- That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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