Cheap Flights from Santa Ana, CA to Chicago, IL from $71

Return flight: Chicago – Santa Ana

On Cheapflightsplus.com you will find 17 direct and 279 connecting flights from Santa Ana to Chicago. You can compare airfare deals from 7 airlines and multiple travel sites from $71, book and save on cheap plane tickets and last minute offers. Also check out SNA-CHI flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Santa Ana to Chicago Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $71 (one-way), $122 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Santa Ana to Chicago. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
06:45 — 13:06
06:45 — 13:06 UA2649 United Airlines
Santa Ana — Chicago
4h 21m
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from$189
07:55 — 14:05
07:55 — 14:05 AS4336 Alaska Airlines
Santa Ana — Chicago
4h 10m
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from$178
10:19 — 16:37
10:19 — 16:37 AS4756 Alaska Airlines
Santa Ana — Chicago
4h 18m
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from$175
10:19 — 16:30
10:19 — 16:30 AS6068 Alaska Airlines
Santa Ana — Chicago
4h 11m
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from$214
10:30 — 16:41
10:30 — 16:41 UA2849 United Airlines
Santa Ana — Chicago
4h 11m
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from$177
10:30 — 16:41
10:30 — 16:41 UA2075 United Airlines
Santa Ana — Chicago
4h 11m
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from$198
10:30 — 16:41
10:30 — 16:41 UA2202 United Airlines
Santa Ana — Chicago
4h 11m
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from$214
10:38 — 16:52
10:38 — 16:52 AS4625 Alaska Airlines
Santa Ana — Chicago
4h 14m
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from$200
11:28 — 17:46
11:28 — 17:46 AS6077 Alaska Airlines
Santa Ana — Chicago
4h 18m
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from$405
11:32 — 17:43
11:32 — 17:43 AS4238 Alaska Airlines
Santa Ana — Chicago
4h 11m
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from$200
11:34 — 17:48
11:34 — 17:48 AS4714 Alaska Airlines
Santa Ana — Chicago
4h 14m
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from$189
13:48 — 19:59
13:48 — 19:59 UA1383 United Airlines
Santa Ana — Chicago
4h 11m
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from$177
13:48 — 19:59
13:48 — 19:59 UA276 United Airlines
Santa Ana — Chicago
4h 11m
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from$178
14:02 — 20:13
14:02 — 20:13 UA1641 United Airlines
Santa Ana — Chicago
4h 11m
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from$189
15:07 — 21:24
15:07 — 21:24 AS4237 Alaska Airlines
Santa Ana — Chicago
4h 17m
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from$175
15:07 — 21:24
15:07 — 21:24 AS4532 Alaska Airlines
Santa Ana — Chicago
4h 17m
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from$214
15:09 — 21:24
15:09 — 21:24 AS4546 Alaska Airlines
Santa Ana — Chicago
4h 15m
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from$189
06:45 — 14:16
06:45 — 07:57 NK870 Spirit Airlines
Santa Ana — Las Vegas
35m stop
08:32 — 14:16 NK187 Spirit Airlines
Las Vegas — Chicago
5h 31m
including layover
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from$71
06:45 — 23:43
06:45 — 07:57 NK870 Spirit Airlines
Santa Ana — Las Vegas
9h 59m stop
17:56 — 23:43 NK184 Spirit Airlines
Las Vegas — Chicago
14h 58m
including layover
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from$71
07:45 — 06:12
+1 day
07:45 — 09:08 NK2095 Spirit Airlines
Santa Ana — Las Vegas
15h 36m stop
00:44 — 06:12 NK2186 Spirit Airlines
Las Vegas — Chicago
20h 27m
including layover
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from$87
07:45 — 10:50
+1 day
07:45 — 09:08 NK2095 Spirit Airlines
Santa Ana — Las Vegas
20h 7m stop
05:15 — 10:50 NK2619 Spirit Airlines
Las Vegas — Chicago
25h 5m
including layover
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from$87
09:12 — 06:12
+1 day
09:12 — 10:32 NK2017 Spirit Airlines
Santa Ana — Las Vegas
14h 12m stop
00:44 — 06:12 NK2186 Spirit Airlines
Las Vegas — Chicago
19h
including layover
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from$87
09:12 — 10:50
+1 day
09:12 — 10:32 NK2017 Spirit Airlines
Santa Ana — Las Vegas
18h 43m stop
05:15 — 10:50 NK2619 Spirit Airlines
Las Vegas — Chicago
23h 38m
including layover
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from$87
10:23 — 22:04
10:21 — 13:06 HA7114 Hawaiian Airlines
Santa Ana — Seattle
2h 46m stop
16:25 — 22:30 HA6821 Hawaiian Airlines
Seattle — Chicago
9h 41m
including layover
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from$93
10:23 — 22:04
10:21 — 13:06 AS1277 Alaska Airlines
Santa Ana — Seattle
2h 46m stop
16:25 — 22:30 AS941 Alaska Airlines
Seattle — Chicago
9h 41m
including layover
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from$100
12:01 — 23:59
12:01 — 15:35 F94372 Frontier Airlines
Santa Ana — Denver
4h 52m stop
20:31 — 00:10 F93174 Frontier Airlines
Denver — Chicago
9h 58m
including layover
Find flight
from$84
12:18 — 23:53
10:47 — 14:04 F94372 Frontier Airlines
Santa Ana — Denver
4h 34m stop
20:59 — 00:35 F93172 Frontier Airlines
Denver — Chicago
9h 35m
including layover
Find flight
from$88
13:30 — 23:59
13:30 — 16:15 HA7108 Hawaiian Airlines
Santa Ana — Seattle
1h 39m stop
17:54 — 23:59 HA6819 Hawaiian Airlines
Seattle — Chicago
8h 29m
including layover
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from$111
14:03 — 23:59
14:03 — 16:30 HA7104 Hawaiian Airlines
Santa Ana — Portland
1h 20m stop
17:50 — 23:59 HA4829 Hawaiian Airlines
Portland — Chicago
7h 56m
including layover
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from$93
14:03 — 23:59
14:03 — 16:30 AS1159 Alaska Airlines
Santa Ana — Portland
1h 20m stop
17:50 — 23:59 AS370 Alaska Airlines
Portland — Chicago
7h 56m
including layover
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from$100
15:31 — 23:43
15:31 — 16:45 NK874 Spirit Airlines
Santa Ana — Las Vegas
1h 11m stop
17:56 — 23:43 NK184 Spirit Airlines
Las Vegas — Chicago
6h 12m
including layover
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from$71
15:37 — 06:03
+1 day
15:37 — 16:58 NK1163 Spirit Airlines
Santa Ana — Las Vegas
7h 36m stop
00:34 — 06:03 NK1053 Spirit Airlines
Las Vegas — Chicago
12h 26m
including layover
Find flight
from$72
17:22 — 06:12
+1 day
17:22 — 18:44 NK3171 Spirit Airlines
Santa Ana — Las Vegas
6h stop
00:44 — 06:12 NK2186 Spirit Airlines
Las Vegas — Chicago
10h 50m
including layover
Find flight
from$78
17:22 — 10:50
+1 day
17:22 — 18:44 NK3171 Spirit Airlines
Santa Ana — Las Vegas
10h 31m stop
05:15 — 10:50 NK2619 Spirit Airlines
Las Vegas — Chicago
15h 28m
including layover
Find flight
from$87
19:40 — 06:12
+1 day
19:40 — 20:56 NK2337 Spirit Airlines
Santa Ana — Las Vegas
3h 48m stop
00:44 — 06:12 NK2186 Spirit Airlines
Las Vegas — Chicago
8h 32m
including layover
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from$78
19:58 — 06:03
+1 day
19:58 — 21:14 NK1447 Spirit Airlines
Santa Ana — Las Vegas
3h 20m stop
00:34 — 06:03 NK1053 Spirit Airlines
Las Vegas — Chicago
8h 5m
including layover
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from$72
21:15 — 07:03
+1 day
21:15 — 23:59 HA6841 Hawaiian Airlines
Santa Ana — Seattle
1h stop
00:59 — 07:03 HA6669 Hawaiian Airlines
Seattle — Chicago
7h 48m
including layover
Find flight
from$110
*Departure and arrival times - local. Updated on July 2, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Santa Ana to Chicago depends on and how to choose the most interesting flight option for you.

Distance between Santa Ana and Chicago is 2792 miles. Time difference between the cities is 2h. Airplanes depart 06:45 to 21:15 from 3 Santa Ana airports and arrive 06:45 to 21:15 to 7 Chicago airports. Average flight time is 4h 11m.

  • The fastest flight 4h 10m
  • Average flight time 4h 11m
  • The earliest flight 06:45
  • The latest flight 21:15
  • Distance 1735 ml

The cheapest months to travel to Chicago are november (from 69 $), july (from 69 $), january (from 92 $).

The most expensive months are september (from 108 $), october (from 108 $), december (from 97 $).

What is the lowest airfare Santa Ana to Chicago?

The cheapest plane ticket found by our users is $71. This airfare is for economy class on one-way NK870 flight by Spirit Airlines for August 27, 2025 which leaves John Wayne in Santa Ana at 06:45 am and arrives at Chicago O'Hare International at 14:16.

Economy class
$71
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Business class
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First class
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Popular Airlines on the Route

The flight Santa Ana — Chicago is served by 7 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 55 departures per week at the price of from $ 100 . And the most expensive tickets are offered by United Airlines airline - from $ 491.

Direct flights

There are 17 nonstop flights on the route. The fastest direct flight is AS4336 by Alaska Airlines takes 4h 10m and the cheapest is NK870 by Spirit Airlines for $175.

  • AS - Alaska Airlines
    from $175
    Find
  • UA - United Airlines
    from $177
    Find
See more direct flights

Connecting Flights

There are 279 flights with layovers on the route. The fastest connecting flight is NK870 by Spirit Airlines takes 5h 31m and the cheapest is NK870 by Spirit Airlines for $71.

  • AS - Alaska Airlines
    from $100
    Find
  • F9 - Frontier Airlines
    from $84
    Find
  • HA - Hawaiian Airlines
    from $93
    Find
  • MX - Mexicana
    from $270
    Find
  • UA - United Airlines
    from $183
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  • NK - Spirit Airlines
    from $71
    Find
  • G4 - Allegiant Air
    from $144
    Find
See more connecting flights

Airports

You can fly from Santa Ana to Chicago from 3 airports (John Wayne, Santa Ana Heliport, Centerport Heliport).

Santa Ana airports

  • John Wayne-SNA
    from $71
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  • Santa Ana Heliport-DNT
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  • Centerport Heliport-JOC
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Chicago airports

  • O'Hare International-ORD
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  • Midway-MDW
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  • Dupage County-DPA
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  • Chicago FSS-CHI
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  • Merrill C Meigs (closed)-CGX
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  • Pal-Waukee-PWK
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  • Chicago NAS-NOH
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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