Cheap Flights from Chicago, IL to Santa Ana, CA from $77

Return flight: Santa Ana – Chicago

On Cheapflightsplus.com you will find 17 direct and 259 connecting flights from Chicago to Santa Ana. You can compare airfare deals from 7 airlines and multiple travel sites from $77, book and save on cheap plane tickets and last minute offers. Also check out CHI-SNA flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Chicago to Santa Ana depends on and how to choose the most interesting flight option for you.

Distance between Chicago and Santa Ana is 2792 miles. Time difference between the cities is 2h. Airplanes depart 05:00 to 22:15 from 7 Chicago airports and arrive 05:00 to 22:15 to 3 Santa Ana airports. Average flight time is 4h 26m.

  • The fastest flight 4h 13m
  • Average flight time 4h 26m
  • The earliest flight 05:00
  • The latest flight 22:15
  • Distance 1735 ml

The cheapest months to travel to Santa Ana are august (from 77 $), july (from 97 $), october (from 102 $).

The most expensive months are february (from 277 $), january (from 277 $), december (from 262 $).

What is the lowest airfare Chicago to Santa Ana?

The cheapest plane ticket found by our users is $77. This airfare is for economy class on one-way NK188 flight by Spirit Airlines for October 7, 2025 which leaves O'Hare International in Chicago at 15:21 am and arrives at Santa Ana John Wayne at 21:41.

Economy class
$77
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Business class
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First class
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Flight Schedule Chicago (Illinois) to Santa Ana (California)

07:00 — 11:11
6h 11m flight time
Find flight
from$97
18:06 — 20:04 Chicago — Denver
F91483 Frontier Airlines
50m stop
11:44 — 13:15 Denver — Santa Ana
F94371 Frontier Airlines
07:09 — 09:24
4h 15m flight time
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from$223
Chicago — Santa Ana
AS4238 Alaska Airlines
08:25 — 10:38
4h 13m flight time
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from$223
Chicago — Santa Ana
AS4237 Alaska Airlines
08:25 — 10:44
4h 19m flight time
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from$226
Chicago — Santa Ana
AS4546 Alaska Airlines
09:04 — 11:38
4h 34m flight time
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from$242
Chicago — Santa Ana
UA2609 United Airlines
11:00 — 21:41
12h 41m flight time
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from$90
11:00 — 12:56 Chicago — Las Vegas
NK183 Spirit Airlines
7h 34m stop
20:30 — 21:41 Las Vegas — Santa Ana
NK891 Spirit Airlines
12:01 — 14:17
4h 16m flight time
Find flight
from$239
Chicago — Santa Ana
AS4740 Alaska Airlines
12:02 — 14:19
4h 17m flight time
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from$226
Chicago — Santa Ana
AS4601 Alaska Airlines
15:21 — 21:41
8h 20m flight time
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from$77
15:21 — 17:16 Chicago — Las Vegas
NK188 Spirit Airlines
3h 14m stop
20:30 — 21:41 Las Vegas — Santa Ana
NK891 Spirit Airlines
16:10 — 18:36
4h 26m flight time
Find flight
from$228
Chicago — Santa Ana
UA1683 United Airlines
16:10 — 18:36
4h 26m flight time
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from$238
Chicago — Santa Ana
UA257 United Airlines
16:50 — 19:18
4h 28m flight time
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from$242
Chicago — Santa Ana
UA1859 United Airlines
18:48 — 21:17
4h 29m flight time
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from$274
Chicago — Santa Ana
AS6050 Alaska Airlines
19:58 — 22:30
4h 32m flight time
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from$223
Chicago — Santa Ana
UA308 United Airlines
19:58 — 22:30
4h 32m flight time
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from$228
Chicago — Santa Ana
UA516 United Airlines
Full flight schedule will help you in detecting at what time planes fly from Chicago to Santa Ana. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on October 23, 2025.

Popular Airlines on the Route

The flight Chicago — Santa Ana is served by 7 regular airlines and 4 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 54 departures per week at the price of from $ 128 . And the most expensive tickets are offered by United Airlines airline - from $ 623.

Direct flights

There are 17 nonstop flights on the route. The fastest direct flight is AS4237 by Alaska Airlines takes 4h 13m and the cheapest is NK188 by Spirit Airlines for $223.

  • AS - Alaska Airlines
    from $223
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  • UA - United Airlines
    from $223
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Connecting Flights

There are 259 flights with layovers on the route. The fastest connecting flight is UA1803 by United Airlines takes 5h 54m and the cheapest is NK188 by Spirit Airlines for $77.

  • AS - Alaska Airlines
    from $128
    Find
  • F9 - Frontier Airlines
    from $97
    Find
  • SY - Sun Country Airlines
    from $172
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  • HA - Hawaiian Airlines
    from $121
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  • UA - United Airlines
    from $199
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  • NK - Spirit Airlines
    from $77
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  • G4 - Allegiant Air
    from $102
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Airports

You can fly from Chicago to Santa Ana from 7 airports (O'Hare International, Midway, Dupage County, Chicago FSS, Merrill C Meigs (closed), Pal-Waukee, Chicago NAS).

Chicago airports

  • O'Hare International-ORD
    from $77
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  • Midway-MDW
    from $102
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  • Dupage County-DPA
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  • Chicago FSS-CHI
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  • Merrill C Meigs (closed)-CGX
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  • Pal-Waukee-PWK
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  • Chicago NAS-NOH
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Santa Ana airports

  • John Wayne-SNA
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  • Santa Ana Heliport-DNT
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  • Centerport Heliport-JOC
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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