Cheap Flights from Chicago, IL to Santa Ana, CA from $90

Return flight: Santa Ana – Chicago
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On Cheapflightsplus.com you will find 17 direct and 259 connecting flights from Chicago to Santa Ana. You can compare airfare deals from 7 airlines and multiple travel sites from $90, book and save on cheap plane tickets and last minute offers. Also check out CHI-SNA flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Chicago to Santa Ana Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $90 (one-way), $154 (round-trip).
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Best Flights from Chicago to Santa Ana Today

Take a look at the list of non stop flights and flights with layovers from Chicago to Santa Ana with the lowest price of $90. The fastest direct flight takes 4h 13m and the fastest connecting – 5h 54m.
Price Departure Arrival Flight Duration Airline Flight
from $222
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08:25
Chicago
O'Hare International
 10:38
Santa Ana
John Wayne
 4h 13m Alaska Airlines
AS4237
from $222
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19:58
Chicago
O'Hare International
 22:30
Santa Ana
John Wayne
 4h 32m United Airlines
UA308
from $270
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12:02
Chicago
O'Hare International
 14:18
Santa Ana
John Wayne
 4h 16m Alaska Airlines
AS4236
from $90
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11:00
Chicago
O'Hare International
 21:41
Santa Ana
John Wayne
 12h 41m
layover
7h 34m - Las Vegas
 Spirit Airlines
NK183
NK891
from $96
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07:00
Chicago
O'Hare International
 11:11
Santa Ana
John Wayne
 6h 11m
layover
0h 50m - Denver
 Frontier Airlines
F91483
F94371
from $130
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08:00
Chicago
O'Hare International
 21:41
Santa Ana
John Wayne
 15h 41m
layover
6h 5m - Los Angeles
2h 38m - Las Vegas
 Spirit Airlines
NK3016
NK1494
NK891
from $139
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09:12
Chicago
Midway
 07:16+1 день
Santa Ana
John Wayne
 24h 4m
layover
9h 45m - Fort Walton Beach
6h 39m - Las Vegas
 Allegiant Air
G43081
G4126
NK2016
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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 17, 2025
Full flight schedule will help you in detecting at what time planes fly from Chicago to Santa Ana. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
07:00 — 11:11
18:06 — 20:04 F91483 Frontier Airlines
Chicago — Denver
50m stop
11:44 — 13:15 F94371 Frontier Airlines
Denver — Santa Ana
6h 11m
including layover
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from$96
07:09 — 09:24
07:09 — 09:24 AS4238 Alaska Airlines
Chicago — Santa Ana
4h 15m
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from$222
08:25 — 10:38
08:25 — 10:38 AS4237 Alaska Airlines
Chicago — Santa Ana
4h 13m
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from$222
08:25 — 10:44
08:25 — 10:44 AS4546 Alaska Airlines
Chicago — Santa Ana
4h 19m
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from$225
09:04 — 11:38
09:04 — 11:38 UA2609 United Airlines
Chicago — Santa Ana
4h 34m
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from$240
11:00 — 21:41
11:00 — 12:56 NK183 Spirit Airlines
Chicago — Las Vegas
7h 34m stop
20:30 — 21:41 NK891 Spirit Airlines
Las Vegas — Santa Ana
12h 41m
including layover
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from$90
12:01 — 14:17
12:01 — 14:17 AS4740 Alaska Airlines
Chicago — Santa Ana
4h 16m
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from$238
12:02 — 14:19
12:02 — 14:19 AS4601 Alaska Airlines
Chicago — Santa Ana
4h 17m
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from$225
14:15 — 19:46
14:15 — 16:21 F91829 Frontier Airlines
Chicago — Phoenix
2h 7m stop
18:28 — 19:46 F94591 Frontier Airlines
Phoenix — Santa Ana
7h 31m
including layover
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from$96
16:10 — 18:36
16:10 — 18:36 UA257 United Airlines
Chicago — Santa Ana
4h 26m
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from$236
16:10 — 18:36
16:10 — 18:36 UA1683 United Airlines
Chicago — Santa Ana
4h 26m
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from$249
16:50 — 19:18
16:50 — 19:18 UA1859 United Airlines
Chicago — Santa Ana
4h 28m
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from$240
18:48 — 21:17
18:48 — 21:17 AS6050 Alaska Airlines
Chicago — Santa Ana
4h 29m
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from$273
19:58 — 22:30
19:58 — 22:30 UA308 United Airlines
Chicago — Santa Ana
4h 32m
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from$222
19:58 — 22:30
19:58 — 22:30 UA516 United Airlines
Chicago — Santa Ana
4h 32m
Find flight
from$227
*Departure and arrival times - local. Updated on September 17, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Chicago to Santa Ana depends on and how to choose the most interesting flight option for you.

Distance between Chicago and Santa Ana is 2792 miles. Time difference between the cities is 2h. Airplanes depart 05:00 to 22:15 from 7 Chicago airports and arrive 05:00 to 22:15 to 3 Santa Ana airports. Average flight time is 4h 26m.

  • The fastest flight 4h 13m
  • Average flight time 4h 26m
  • The earliest flight 05:00
  • The latest flight 22:15
  • Distance 1735 ml

The cheapest months to travel to Santa Ana are august (from 76 $), july (from 96 $), october (from 102 $).

The most expensive months are february (from 275 $), january (from 275 $), december (from 261 $).

What is the lowest airfare Chicago to Santa Ana?

The cheapest plane ticket found by our users is $90. This airfare is for economy class on one-way NK183 flight by Spirit Airlines for August 27, 2025 which leaves O'Hare International in Chicago at 11:00 am and arrives at Santa Ana John Wayne at 21:41.

Economy class
$90
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Business class
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First class
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Popular Airlines on the Route

The flight Chicago — Santa Ana is served by 7 regular airlines and 4 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 54 departures per week at the price of from $ 127 . And the most expensive tickets are offered by United Airlines airline - from $ 620.

Direct flights

There are 17 nonstop flights on the route. The fastest direct flight is AS4237 by Alaska Airlines takes 4h 13m and the cheapest is NK183 by Spirit Airlines for $222.

  • AS - Alaska Airlines
    from $222
    Find
  • UA - United Airlines
    from $222
    Find
See more direct flights

Connecting Flights

There are 259 flights with layovers on the route. The fastest connecting flight is UA1803 by United Airlines takes 5h 54m and the cheapest is NK183 by Spirit Airlines for $90.

  • AS - Alaska Airlines
    from $127
    Find
  • F9 - Frontier Airlines
    from $96
    Find
  • SY - Sun Country Airlines
    from $171
    Find
  • HA - Hawaiian Airlines
    from $138
    Find
  • UA - United Airlines
    from $198
    Find
  • NK - Spirit Airlines
    from $90
    Find
  • G4 - Allegiant Air
    from $101
    Find
See more connecting flights

Airports

You can fly from Chicago to Santa Ana from 7 airports (O'Hare International, Midway, Dupage County, Chicago FSS, Merrill C Meigs (closed), Pal-Waukee, Chicago NAS).

Chicago airports

  • O'Hare International-ORD
    from $90
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  • Midway-MDW
    from $101
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  • Dupage County-DPA
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  • Chicago FSS-CHI
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  • Merrill C Meigs (closed)-CGX
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  • Pal-Waukee-PWK
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  • Chicago NAS-NOH
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Santa Ana airports

  • John Wayne-SNA
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  • Santa Ana Heliport-DNT
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  • Centerport Heliport-JOC
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Airplanes

There are flights to Santa Ana from Chicago by 7 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Chicago

You may also consider searching for discounted plane tickets to some other popular places from Chicago within United States.

Top International Destinations from Chicago

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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