Cheap Flights from Chicago, IL to Santa Ana, CA from $81
Return flight: Santa Ana – Chicago
On Cheapflightsplus.com you will find 17 direct and 242 connecting flights from Chicago to Santa Ana. You can compare airfare deals from 7 airlines and multiple travel sites from $81, book and save on cheap plane tickets and last minute offers. Also check out CHI-SNA flight schedule to find best flight time, convenient departure and arrival airports.
Find One-Way and Round-Trip Chicago to Santa Ana Flight Deals
To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights».
To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight.
Cheapest flights in November: $81 (one-way), $139 (round-trip).
Direct flights
Check prices for return flight
Best Flights from Chicago to Santa Ana Today
Take a look at the list of non stop flights and flights with layovers from Chicago to Santa Ana with the lowest price of $81. The fastest direct flight takes 4h 13m and the fastest connecting – 5h 54m.
| Price | Departure | Arrival | Flight Duration | Airline | Flight |
|---|---|---|---|---|---|
| from $234 | 08:25 Chicago O'Hare International | 10:38 Santa Ana John Wayne | 4h 13m | Alaska Airlines | AS4237 |
| from $234 | 19:58 Chicago O'Hare International | 22:30 Santa Ana John Wayne | 4h 32m | United Airlines | UA308 |
| from $287 | 19:50 Chicago O'Hare International | 22:17 Santa Ana John Wayne | 4h 27m | United Airlines | UA1673 |
| from $289 | 08:25 Chicago O'Hare International | 10:38 Santa Ana John Wayne | 4h 13m | Alaska Airlines | AS6826 |
| from $427 | 12:01 Chicago O'Hare International | 14:17 Santa Ana John Wayne | 4h 16m | Alaska Airlines | AS4272 |
| from $81 | 15:21 Chicago O'Hare International | 21:41 Santa Ana John Wayne | 8h 20m layover 3h 14m - Las Vegas | Spirit Airlines | NK188 NK891 |
| from $95 | 11:00 Chicago O'Hare International | 21:41 Santa Ana John Wayne | 12h 41m layover 7h 34m - Las Vegas | Spirit Airlines | NK183 NK891 |
| from $102 | 07:00 Chicago O'Hare International | 11:11 Santa Ana John Wayne | 6h 11m layover 0h 50m - Denver | Frontier Airlines | F91483 F94371 |
| from $102 | 14:15 Chicago O'Hare International | 19:46 Santa Ana John Wayne | 7h 31m layover 2h 7m - Phoenix | Frontier Airlines | F91829 F94591 |
| from $107 | 20:14 Chicago Midway | 12:01+1 день Santa Ana John Wayne | 17h 47m layover 12h 45m - Provo | Allegiant Air | G43225 G43244 |
| from $112 | 14:44 Chicago Midway | 11:10+1 день Santa Ana John Wayne | 22h 26m layover 17h 9m - Denver | Frontier Airlines | F92209 F94371 |
| from $113 | 07:09 Chicago O'Hare International | 11:10 Santa Ana John Wayne | 6h 1m layover 0h 56m - Las Vegas | Spirit Airlines | NK1033 NK1160 |
| from $113 | 15:51 Chicago O'Hare International | 21:21 Santa Ana John Wayne | 7h 30m layover 2h 23m - Las Vegas | Spirit Airlines | NK1270 NK1158 |
| from $113 | 07:09 Chicago O'Hare International | 19:03 Santa Ana John Wayne | 13h 54m layover 8h 45m - Las Vegas | Spirit Airlines | NK1033 NK1446 |
| from $137 | 08:00 Chicago O'Hare International | 21:41 Santa Ana John Wayne | 15h 41m layover 6h 5m - Los Angeles 2h 38m - Las Vegas | Spirit Airlines | NK3016 NK1494 NK891 |
| from $163 | 16:45 Chicago O'Hare International | 08:17+1 день Santa Ana John Wayne | 17h 32m layover 1h 32m - Miami 6h 21m - Las Vegas | Spirit Airlines | NK2187 NK777 NK2016 |
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on July 05, 2025
Flight Schedule Chicago (Illinois) to Santa Ana (California)
Full flight schedule will help you in detecting at what time planes fly from Chicago to Santa Ana. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
| Departure | Arrival | Flight Details | Flight Duration | Price |
|---|---|---|---|---|
|
07:09 — 09:24
|
07:09 — 09:24
AS4238
Alaska Airlines
Chicago — Santa Ana
|
4h 15m |
Find flight
from$234 |
|
|
08:25 — 10:38
|
08:25 — 10:38
AS4237
Alaska Airlines
Chicago — Santa Ana
|
4h 13m |
Find flight
from$234 |
|
|
08:25 — 10:44
|
08:25 — 10:44
AS4546
Alaska Airlines
Chicago — Santa Ana
|
4h 19m |
Find flight
from$238 |
|
|
08:25 — 10:38
|
08:25 — 10:38
AS6826
Alaska Airlines
Chicago — Santa Ana
|
4h 13m |
Find flight
from$289 |
|
|
09:04 — 11:38
|
09:04 — 11:38
UA2609
United Airlines
Chicago — Santa Ana
|
4h 34m |
Find flight
from$254 |
|
|
12:01 — 14:17
|
12:01 — 14:17
AS4740
Alaska Airlines
Chicago — Santa Ana
|
4h 16m |
Find flight
from$251 |
|
|
12:01 — 14:17
|
12:01 — 14:17
AS4272
Alaska Airlines
Chicago — Santa Ana
|
4h 16m |
Find flight
from$427 |
|
|
12:02 — 14:19
|
12:02 — 14:19
AS4601
Alaska Airlines
Chicago — Santa Ana
|
4h 17m |
Find flight
from$238 |
|
|
12:02 — 14:18
|
12:02 — 14:18
AS4236
Alaska Airlines
Chicago — Santa Ana
|
4h 16m |
Find flight
from$292 |
|
|
16:10 — 18:36
|
16:10 — 18:36
UA1683
United Airlines
Chicago — Santa Ana
|
4h 26m |
Find flight
from$240 |
|
|
16:10 — 18:36
|
16:10 — 18:36
UA257
United Airlines
Chicago — Santa Ana
|
4h 26m |
Find flight
from$250 |
|
|
16:50 — 19:18
|
16:50 — 19:18
UA1859
United Airlines
Chicago — Santa Ana
|
4h 28m |
Find flight
from$254 |
|
|
18:48 — 21:17
|
18:48 — 21:17
AS6050
Alaska Airlines
Chicago — Santa Ana
|
4h 29m |
Find flight
from$289 |
|
|
19:50 — 22:17
|
19:50 — 22:17
UA658
United Airlines
Chicago — Santa Ana
|
4h 27m |
Find flight
from$265 |
|
|
19:50 — 22:17
|
19:50 — 22:17
UA1673
United Airlines
Chicago — Santa Ana
|
4h 27m |
Find flight
from$287 |
|
|
19:58 — 22:30
|
19:58 — 22:30
UA308
United Airlines
Chicago — Santa Ana
|
4h 32m |
Find flight
from$234 |
|
|
19:58 — 22:30
|
19:58 — 22:30
UA516
United Airlines
Chicago — Santa Ana
|
4h 32m |
Find flight
from$240 |
|
|
06:00 — 10:01
|
06:00 — 07:54
NK183
Spirit Airlines
Chicago — Las Vegas
58m stop
08:52 — 10:01
NK871
Spirit Airlines
Las Vegas — Santa Ana
|
6h 1m including layover |
Find flight
from$108 |
|
|
07:00 — 11:11
|
18:06 — 20:04
F91483
Frontier Airlines
Chicago — Denver
50m stop
11:44 — 13:15
F94371
Frontier Airlines
Denver — Santa Ana
|
6h 11m including layover |
Find flight
from$102 |
|
|
07:09 — 11:10
|
07:09 — 09:07
NK1033
Spirit Airlines
Chicago — Las Vegas
56m stop
10:03 — 11:10
NK1160
Spirit Airlines
Las Vegas — Santa Ana
|
6h 1m including layover |
Find flight
from$113 |
|
|
10:00 — 18:28
|
10:00 — 12:34
HA6295
Hawaiian Airlines
Chicago — Seattle
3h 5m stop
15:39 — 18:28
HA6619
Hawaiian Airlines
Seattle — Santa Ana
|
10h 28m including layover |
Find flight
from$149 |
|
|
11:00 — 21:41
|
11:00 — 12:56
NK183
Spirit Airlines
Chicago — Las Vegas
7h 34m stop
20:30 — 21:41
NK891
Spirit Airlines
Las Vegas — Santa Ana
|
12h 41m including layover |
Find flight
from$95 |
|
|
11:50 — 07:16
+1 day
|
11:50 — 13:50
NK2620
Spirit Airlines
Chicago — Las Vegas
16h 25m stop
06:15 — 07:16
NK2016
Spirit Airlines
Las Vegas — Santa Ana
|
21h 26m including layover |
Find flight
from$144 |
|
|
13:03 — 20:25
|
13:03 — 15:42
HA6300
Hawaiian Airlines
Chicago — Seattle
1h 53m stop
17:35 — 20:25
HA6934
Hawaiian Airlines
Seattle — Santa Ana
|
9h 22m including layover |
Find flight
from$149 |
|
|
13:03 — 21:39
|
13:03 — 15:42
HA6300
Hawaiian Airlines
Chicago — Seattle
3h 8m stop
18:50 — 21:39
HA6929
Hawaiian Airlines
Seattle — Santa Ana
|
10h 36m including layover |
Find flight
from$149 |
|
|
14:15 — 19:46
|
14:15 — 16:21
F91829
Frontier Airlines
Chicago — Phoenix
2h 7m stop
18:28 — 19:46
F94591
Frontier Airlines
Phoenix — Santa Ana
|
7h 31m including layover |
Find flight
from$102 |
|
|
14:44 — 11:10
+1 day
|
12:35 — 14:19
F92209
Frontier Airlines
Chicago — Denver
17h 9m stop
09:43 — 11:11
F94371
Frontier Airlines
Denver — Santa Ana
|
22h 26m including layover |
Find flight
from$112 |
|
|
15:21 — 21:41
|
15:21 — 17:16
NK188
Spirit Airlines
Chicago — Las Vegas
3h 14m stop
20:30 — 21:41
NK891
Spirit Airlines
Las Vegas — Santa Ana
|
8h 20m including layover |
Find flight
from$81 |
|
|
15:51 — 21:21
|
15:51 — 17:52
NK1270
Spirit Airlines
Chicago — Las Vegas
2h 23m stop
20:15 — 21:21
NK1158
Spirit Airlines
Las Vegas — Santa Ana
|
7h 30m including layover |
Find flight
from$113 |
|
|
20:14 — 12:01
+1 day
|
20:14 — 22:30
G43225
Allegiant Air
Chicago — Provo
12h 45m stop
11:15 — 12:01
G43244
Allegiant Air
Provo — Santa Ana
|
17h 47m including layover |
Find flight
from$107 |
|
|
20:14 — 08:46
+1 day
|
20:14 — 22:30
G43225
Allegiant Air
Chicago — Provo
9h 30m stop
08:00 — 08:46
G43233
Allegiant Air
Provo — Santa Ana
|
14h 32m including layover |
Find flight
from$120 |
|
|
21:56 — 18:40
+1 day
|
21:56 — 00:05
F92145
Frontier Airlines
Chicago — Las Vegas
17h 21m stop
17:26 — 18:40
F93737
Frontier Airlines
Las Vegas — Santa Ana
|
22h 44m including layover |
Find flight
from$138 |
|
|
22:15 — 07:16
+1 day
|
22:15 — 00:19
NK2179
Spirit Airlines
Chicago — Las Vegas
5h 56m stop
07:15 — 08:17
NK2016
Spirit Airlines
Las Vegas — Santa Ana
|
11h 1m including layover |
Find flight
from$114 |
|
|
22:15 — 14:09
+1 day
|
22:15 — 00:19
NK2179
Spirit Airlines
Chicago — Las Vegas
12h 39m stop
12:58 — 14:09
NK2334
Spirit Airlines
Las Vegas — Santa Ana
|
17h 54m including layover |
Find flight
from$116 |
|
|
06:45 — 21:41
|
06:45 — 09:07
NK467
Spirit Airlines
Chicago — Los Angeles
7h 24m stop
16:31 — 17:52
NK1494
Spirit Airlines
Los Angeles — Las Vegas
2h 38m stop
20:30 — 21:41
NK891
Spirit Airlines
Las Vegas — Santa Ana
|
16h 56m including layover |
Find flight
from$137 |
|
|
08:00 — 21:41
|
08:00 — 10:26
NK3016
Spirit Airlines
Chicago — Los Angeles
6h 5m stop
16:31 — 17:52
NK1494
Spirit Airlines
Los Angeles — Las Vegas
2h 38m stop
20:30 — 21:41
NK891
Spirit Airlines
Las Vegas — Santa Ana
|
15h 41m including layover |
Find flight
from$137 |
|
|
08:00 — 10:01
+1 day
|
08:00 — 10:26
NK3016
Spirit Airlines
Chicago — Los Angeles
10h 4m stop
20:30 — 21:53
NK473
Spirit Airlines
Los Angeles — Las Vegas
10h 59m stop
09:56 — 11:05
NK871
Spirit Airlines
Las Vegas — Santa Ana
|
28h 1m including layover |
Find flight
from$137 |
|
*Departure and arrival times - local. Updated on July 5, 2025
Flight Information
Below we will explain in detail what the flights cost on the destination from Chicago to Santa Ana depends on and how to choose the most interesting flight option for you.
Distance between Chicago and Santa Ana is 2792 miles. Time difference between the cities is 2h. Airplanes depart 05:00 to 22:15 from 7 Chicago airports and arrive 05:00 to 22:15 to 3 Santa Ana airports. Average flight time is 4h 26m.
- The fastest flight 4h 13m
- Average flight time 4h 26m
- The earliest flight 05:00
- The latest flight 22:15
- Distance 1735 ml
The cheapest months to travel to Santa Ana are august (from 81 $), july (from 102 $), october (from 108 $).
The most expensive months are february (from 291 $), january (from 291 $), december (from 276 $).
What is the lowest airfare Chicago to Santa Ana?
The cheapest plane ticket found by our users is $81. This airfare is for economy class on one-way NK188 flight by Spirit Airlines for August 16, 2025 which leaves O'Hare International in Chicago at 15:21 am and arrives at Santa Ana John Wayne at 21:41.
Economy class
$81
Business class
?
First class
?
Popular Airlines on the Route
The flight Chicago — Santa Ana is served by 7 regular airlines and 4 low-cost airlines. Most of the flights on this route are operated by United Airlines - 72 departures per week at the price of from $ 209 . And the most expensive tickets are offered by United Airlines airline - from $ 656.
Direct flights
There are 17 nonstop flights on the route. The fastest direct flight is AS4237 by Alaska Airlines takes 4h 13m and the cheapest is NK188 by Spirit Airlines for $234.
- UA - United Airlinesfrom $234Find
- AS - Alaska Airlinesfrom $234Find
See more direct flights
Connecting Flights
There are 242 flights with layovers on the route. The fastest connecting flight is UA1803 by United Airlines takes 5h 54m and the cheapest is NK188 by Spirit Airlines for $81.
- AS - Alaska Airlinesfrom $135Find
- F9 - Frontier Airlinesfrom $102Find
- SY - Sun Country Airlinesfrom $181Find
- HA - Hawaiian Airlinesfrom $127Find
- UA - United Airlinesfrom $209Find
- NK - Spirit Airlinesfrom $81Find
- G4 - Allegiant Airfrom $107Find
See more connecting flights
Airports
You can fly from Chicago to Santa Ana from 7 airports (O'Hare International, Midway, Dupage County, Chicago FSS, Merrill C Meigs (closed), Pal-Waukee, Chicago NAS).
Chicago airports
- O'Hare International-ORDfrom $81Find
- Midway-MDWfrom $107Find
- Dupage County-DPAFind
- Chicago FSS-CHIFind
- Merrill C Meigs (closed)-CGXFind
- Pal-Waukee-PWKFind
- Chicago NAS-NOHFind
Santa Ana airports
- John Wayne-SNAFind
- Santa Ana Heliport-DNTFind
- Centerport Heliport-JOCFind
Airplanes
There are flights to Santa Ana from Chicago by 7 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Chicago
You may also consider searching for discounted plane tickets to some other popular places from Chicago within United States.
- from $508Find
- from $74Find
- from $76Find
- from $62Find
- from $66Find
- from $70Find
- from $66Find
- from $61Find
- from $65Find
- from $61Find
Top International Destinations from Chicago
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
- from $60Find
- from $72Find
- from $73Find
- from $61Find
- from $79Find
- from $73Find
- from $76Find
- from $60Find
- from $59Find
- from $74Find
How to book a plane ticket yourself?
- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
- Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
- Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
- Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
- That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
To find a plane ticket, please select dates.