Cheap Flights from San Diego, CA to Des Moines, IA from $133

On Cheapflightsplus.com you will find 137 connecting flights from San Diego to Des Moines. You can compare airfare deals from 5 airlines and multiple travel sites from $133, book and save on cheap plane tickets and last minute offers. Also check out SAN-DSM flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip San Diego to Des Moines Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $133 (one-way), $228 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from San Diego to Des Moines. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
06:25 — 13:39
06:25 — 09:59 F92818 Frontier Airlines
San Diego — Denver
59m stop
15:19 — 18:01 F91678 Frontier Airlines
Denver — Des Moines
5h 14m
including layover
Find flight
from$143
07:00 — 20:34
07:00 — 10:28 UA2270 United Airlines
San Diego — Denver
7h 22m stop
17:50 — 20:34 UA2324 United Airlines
Denver — Des Moines
11h 34m
including layover
Find flight
from$245
07:00 — 23:49
07:00 — 10:28 UA2270 United Airlines
San Diego — Denver
10h 37m stop
21:05 — 23:49 UA1669 United Airlines
Denver — Des Moines
14h 49m
including layover
Find flight
from$245
08:30 — 17:30
08:30 — 10:54 AS4324 Alaska Airlines
San Diego — Phoenix
2h 46m stop
13:40 — 17:30 AS4791 Alaska Airlines
Phoenix — Des Moines
7h
including layover
Find flight
from$259
08:35 — 23:59
08:35 — 12:03 UA2476 United Airlines
San Diego — Denver
9h stop
21:03 — 23:59 UA4680 United Airlines
Denver — Des Moines
13h 24m
including layover
Find flight
from$267
09:08 — 22:00
09:08 — 10:30 NK376 Spirit Airlines
San Diego — Las Vegas
6h 33m stop
17:03 — 22:00 G4476 Allegiant Air
Las Vegas — Des Moines
10h 52m
including layover
Find flight
from$174
10:20 — 21:46
10:20 — 16:29 UA714 United Airlines
San Diego — Chicago
3h 51m stop
20:20 — 21:46 UA2338 United Airlines
Chicago — Des Moines
9h 26m
including layover
Find flight
from$255
11:15 — 20:34
11:15 — 14:43 UA264 United Airlines
San Diego — Denver
3h 7m stop
17:50 — 20:34 UA2324 United Airlines
Denver — Des Moines
7h 19m
including layover
Find flight
from$255
11:20 — 20:36
11:15 — 14:43 UA264 United Airlines
San Diego — Denver
3h 2m stop
17:50 — 20:34 UA1925 United Airlines
Denver — Des Moines
7h 16m
including layover
Find flight
from$261
12:12 — 22:23
12:12 — 17:25 UA1640 United Airlines
San Diego — Houston
2h 39m stop
20:04 — 22:23 UA1283 United Airlines
Houston — Des Moines
8h 11m
including layover
Find flight
from$255
12:50 — 20:34
12:50 — 16:18 UA1374 United Airlines
San Diego — Denver
1h 32m stop
17:50 — 20:34 UA2324 United Airlines
Denver — Des Moines
5h 44m
including layover
Find flight
from$255
13:34 — 22:23
13:34 — 18:46 UA1382 United Airlines
San Diego — Houston
1h 18m stop
20:04 — 22:23 UA1283 United Airlines
Houston — Des Moines
6h 49m
including layover
Find flight
from$255
13:38 — 22:56
13:38 — 15:00 NK1642 Spirit Airlines
San Diego — Las Vegas
2h 53m stop
17:53 — 22:56 G4438 Allegiant Air
Las Vegas — Des Moines
7h 18m
including layover
Find flight
from$180
14:19 — 13:53
+1 day
15:38 — 19:04 F94990 Frontier Airlines
San Diego — Denver
17h 17m stop
13:23 — 16:07 F91678 Frontier Airlines
Denver — Des Moines
21h 34m
including layover
Find flight
from$138
14:20 — 23:49
14:20 — 17:48 UA280 United Airlines
San Diego — Denver
3h 17m stop
21:05 — 23:49 UA1669 United Airlines
Denver — Des Moines
7h 29m
including layover
Find flight
from$255
15:10 — 22:52
15:10 — 16:33 NK3792 Spirit Airlines
San Diego — Las Vegas
1h 24m stop
17:57 — 22:52 G42100 Allegiant Air
Las Vegas — Des Moines
5h 42m
including layover
Find flight
from$133
15:59 — 23:49
15:59 — 19:27 UA682 United Airlines
San Diego — Denver
1h 38m stop
21:05 — 23:49 UA1669 United Airlines
Denver — Des Moines
5h 50m
including layover
Find flight
from$255
16:10 — 16:13
+1 day
15:59 — 19:27 UA682 United Airlines
San Diego — Denver
17h 49m stop
13:30 — 16:14 UA2265 United Airlines
Denver — Des Moines
22h 3m
including layover
Find flight
from$280
16:11 — 23:59
16:10 — 19:38 UA682 United Airlines
San Diego — Denver
1h 24m stop
21:03 — 23:59 UA4680 United Airlines
Denver — Des Moines
5h 48m
including layover
Find flight
from$261
18:47 — 20:41
+1 day
18:47 — 22:15 UA1924 United Airlines
San Diego — Denver
19h 40m stop
17:55 — 20:41 UA260 United Airlines
Denver — Des Moines
23h 54m
including layover
Find flight
from$313
18:47 — 23:59
+1 day
18:47 — 22:15 UA1924 United Airlines
San Diego — Denver
22h 48m stop
21:03 — 23:59 UA4680 United Airlines
Denver — Des Moines
27h 12m
including layover
Find flight
from$313
22:30 — 10:30
+1 day
22:30 — 04:35 UA2352 United Airlines
San Diego — Chicago
4h 28m stop
09:03 — 10:30 UA3556 United Airlines
Chicago — Des Moines
10h
including layover
Find flight
from$448
22:30 — 14:21
+1 day
22:30 — 04:35 UA2352 United Airlines
San Diego — Chicago
8h 25m stop
13:00 — 14:21 UA247 United Airlines
Chicago — Des Moines
13h 51m
including layover
Find flight
from$448
*Departure and arrival times - local. Updated on December 4, 2024

Flight Information

Below we will explain in detail what the flights cost on the destination from San Diego to Des Moines depends on and how to choose the most interesting flight option for you.

Distance between San Diego and Des Moines is 2295 miles. Time difference between the cities is 2h. Airplanes depart 06:15 to 22:30 from 11 San Diego airport and arrive 06:15 to 22:30 to 1 Des Moines airport. Average flight time is 11h 36m.

  • The fastest flight 5h 14m
  • Average flight time 11h 36m
  • The earliest flight 06:15
  • The latest flight 22:30
  • Distance 1427 ml

The cheapest months to travel to Des Moines are november (from 59 $), february (from 133 $), december (from 138 $).

The most expensive months are january (from 180 $), december (from 138 $), february (from 133 $).

What is the lowest airfare San Diego to Des Moines?

The cheapest plane ticket found by our users is $133. This airfare is for economy class on one-way NK3792 flight by Spirit Airlines for February 21, 2025 which leaves San Diego in San Diego at 15:10 am and arrives at Des Moines Des Moines International Airport at 22:52.

Economy class
$133
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Business class
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First class
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Popular Airlines on the Route

The flight San Diego — Des Moines is served by 5 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 12 departures per week at the price of from $ 259 . And the most expensive tickets are offered by Alaska Airlines airline - from $ 1592.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 137 flights with layovers on the route. The fastest connecting flight is F92818 by Frontier Airlines takes 5h 14m and the cheapest is NK3792 by Spirit Airlines for $133.

  • AS - Alaska Airlines
    from $259
    Find
  • F9 - Frontier Airlines
    from $138
    Find
  • SY - Sun Country Airlines
    from $316
    Find
  • UA - United Airlines
    from $245
    Find
  • NK - Spirit Airlines
    from $133
    Find
See more connecting flights

Airports

You can fly from San Diego to Des Moines from 11 airports (San Diego, San Diego Regional, Gillespie Field, Golden Triangle Reg., El Cajon, Lowndes County, Miramar NAS, Montgomery Field, North Island NAS, Brown Field Municipal, AFB).

San Diego airports

  • San Diego-SAN
    from $133
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  • San Diego Regional-USA
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  • Gillespie Field-SEE
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  • Golden Triangle Reg.-GTR
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  • El Cajon-CJN
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  • Lowndes County-UBS
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  • Miramar NAS-NKX
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  • Montgomery Field-MYF
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  • North Island NAS-NZY
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  • Brown Field Municipal-SDM
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  • AFB-CBM
    Find

Des Moines airports

  • Des Moines International Airport-DSM
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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