Cheap Flights from San Diego, CA to Des Moines, IA from $133

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On Cheapflightsplus.com you will find 11 connecting flights from San Diego to Des Moines. You can compare airfare deals from 2 airlines and multiple travel sites from $133, book and save on cheap plane tickets and last minute offers. Also check out SAN-DSM flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip San Diego to Des Moines Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $133 (one-way), $228 (round-trip).

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Best Flights from San Diego to Des Moines Today

Take a look at the list of non stop flights and flights with layovers from San Diego to Des Moines with the lowest price of $133. Take a look at the list of flights with layovers from San Diego to Des Moines from $133. There’re no direct flights. The fastest connecting flight – 5h 21m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $133 Find flight	15:10 San Diego San Diego	22:52 Des Moines Des Moines International Airport	5h 42m layover 1h 24m - Las Vegas	Spirit Airlines	NK3792 G42100
from $313 Find flight	13:00 San Diego San Diego	20:39 Des Moines Des Moines International Airport	5h 39m layover 1h 29m - Denver	United Airlines	UA1374 UA1925
from $314 Find flight	16:09 San Diego San Diego	23:30 Des Moines Des Moines International Airport	5h 21m layover 1h 3m - Denver	United Airlines	UA682 UA5445
from $364 Find flight	11:10 San Diego San Diego	21:23 Des Moines Des Moines International Airport	8h 13m layover 2h 40m - Chicago	United Airlines	UA714 UA617
from $466 Find flight	12:17 San Diego San Diego	22:30 Des Moines Des Moines International Airport	8h 13m layover 2h 40m - Houston	United Airlines	UA2230 UA1780
from $561 Find flight	10:31 San Diego San Diego	22:30 Des Moines Des Moines International Airport	9h 59m layover 4h 26m - Houston	United Airlines	UA2140 UA1780
from $165 Find flight	08:18 San Diego San Diego	22:52 Des Moines Des Moines International Airport	12h 34m layover 4h 4m - San Jose 2h 46m - Las Vegas	Spirit Airlines	NK1497 NK1371 G42100
from $284 Find flight	15:10 San Diego San Diego	14:42+1 день Des Moines Des Moines International Airport	21h 32m layover 6h 12m - Las Vegas 6h 28m - Clearwater	Spirit Airlines	NK3792 NK900 G42070
from $323 Find flight	20:58 San Diego San Diego	12:44+1 день Des Moines Des Moines International Airport	13h 46m layover 1h 22m - Las Vegas 3h 14m - Sanford	Spirit Airlines	NK1480 NK1853 G42080

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on February 23, 2025

Flight Schedule San Diego (California) to Des Moines (Iowa)

Full flight schedule will help you in detecting at what time planes fly from San Diego to Des Moines. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
10:31 — 22:30	10:31 — 15:39 UA2140 United Airlines San Diego — Houston 4h 26m stop 20:05 — 22:30 UA1780 United Airlines Houston — Des Moines	9h 59m including layover	Find flight from$561
11:10 — 21:23	11:10 — 17:10 UA714 United Airlines San Diego — Chicago 2h 40m stop 19:50 — 21:23 UA617 United Airlines Chicago — Des Moines	8h 13m including layover	Find flight from$364
12:17 — 22:30	12:17 — 17:25 UA2230 United Airlines San Diego — Houston 2h 40m stop 20:05 — 22:30 UA1780 United Airlines Houston — Des Moines	8h 13m including layover	Find flight from$466
13:00 — 20:39	12:55 — 16:23 UA1374 United Airlines San Diego — Denver 1h 29m stop 17:50 — 20:34 UA1925 United Airlines Denver — Des Moines	5h 39m including layover	Find flight from$313
15:10 — 22:52	15:10 — 16:33 NK3792 Spirit Airlines San Diego — Las Vegas 1h 24m stop 17:57 — 22:52 G42100 Allegiant Air Las Vegas — Des Moines	5h 42m including layover	Find flight from$133
16:09 — 23:30	16:09 — 19:35 UA682 United Airlines San Diego — Denver 1h 3m stop 20:38 — 23:30 UA5445 United Airlines Denver — Des Moines	5h 21m including layover	Find flight from$314
08:18 — 22:52	08:18 — 09:41 NK1497 Spirit Airlines San Diego — San Jose 4h 4m stop 13:45 — 15:11 NK1371 Spirit Airlines San Jose — Las Vegas 2h 46m stop 17:57 — 22:52 G42100 Allegiant Air Las Vegas — Des Moines	12h 34m including layover	Find flight from$165
08:18 — 22:52	08:18 — 09:41 NK1497 Spirit Airlines San Diego — San Jose 1h 10m stop 10:51 — 12:18 NK194 Spirit Airlines San Jose — Las Vegas 5h 39m stop 17:57 — 22:52 G42100 Allegiant Air Las Vegas — Des Moines	12h 34m including layover	Find flight from$165
15:10 — 14:42 +1 day	15:10 — 16:33 NK3792 Spirit Airlines San Diego — Las Vegas 6h 12m stop 22:45 — 06:08 NK900 Spirit Airlines Las Vegas — Clearwater 6h 28m stop 12:36 — 14:42 G42070 Allegiant Air Clearwater — Des Moines	21h 32m including layover	Find flight from$284
15:10 — 12:44 +1 day	15:10 — 16:33 NK3792 Spirit Airlines San Diego — Las Vegas 7h 12m stop 23:45 — 07:22 NK1853 Spirit Airlines Las Vegas — Sanford 3h 14m stop 10:36 — 12:44 G42080 Allegiant Air Sanford — Des Moines	19h 34m including layover	Find flight from$323
20:58 — 12:44 +1 day	20:58 — 22:23 NK1480 Spirit Airlines San Diego — Las Vegas 1h 22m stop 23:45 — 07:22 NK1853 Spirit Airlines Las Vegas — Sanford 3h 14m stop 10:36 — 12:44 G42080 Allegiant Air Sanford — Des Moines	13h 46m including layover	Find flight from$323

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on February 23, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from San Diego to Des Moines depends on and how to choose the most interesting flight option for you.

Distance between San Diego and Des Moines is 2295 miles. Time difference between the cities is 2h. Airplanes depart 08:18 to 20:58 from 11 San Diego airport and arrive 08:18 to 20:58 to 1 Des Moines airport. Average flight time is 9h 59m.

The fastest flight 5h 21m
Average flight time 9h 59m
The earliest flight 08:18
The latest flight 20:58
Distance 1427 ml

The cheapest months to travel to Des Moines are february (from 133 $), november (from 313 $).

What is the lowest airfare San Diego to Des Moines?

The cheapest plane ticket found by our users is $133. This airfare is for economy class on one-way NK3792 flight by Spirit Airlines for February 21, 2025 which leaves San Diego in San Diego at 15:10 am and arrives at Des Moines Des Moines International Airport at 22:52.

Economy class

$133

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Business class

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First class

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Popular Airlines on the Route

The flight San Diego — Des Moines is served by 2 regular airlines and 1 low-cost airline. Most of the flights on this route are operated by United Airlines - 5 departures per week at the price of from $ 313 . And the most expensive tickets are offered by United Airlines airline - from $ 561.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 11 flights with layovers on the route. The fastest connecting flight is UA682 by United Airlines takes 5h 21m and the cheapest is NK3792 by Spirit Airlines for $133.

UA - United Airlines

from $313

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NK - Spirit Airlines

from $133

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Airports

You can fly from San Diego to Des Moines from 11 airports (San Diego, San Diego Regional, Gillespie Field, Golden Triangle Reg., El Cajon, Lowndes County, Miramar NAS, Montgomery Field, North Island NAS, Brown Field Municipal, AFB).

San Diego airports

San Diego-SAN

from $133
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San Diego Regional-USA

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Gillespie Field-SEE

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Golden Triangle Reg.-GTR

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El Cajon-CJN

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Lowndes County-UBS

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Miramar NAS-NKX

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Montgomery Field-MYF

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North Island NAS-NZY

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Brown Field Municipal-SDM

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AFB-CBM

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Des Moines airports

Des Moines International Airport-DSM

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Airplanes

There are flights to Des Moines from San Diego by 2 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from San Diego

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Top International Destinations from San Diego

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

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How to book a plane ticket yourself?

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