Cheap Flights from San Diego, CA to Des Moines, IA from $126

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On Cheapflightsplus.com you will find 48 connecting flights from San Diego to Des Moines. You can compare airfare deals from 3 airlines and multiple travel sites from $126, book and save on cheap plane tickets and last minute offers. Also check out SAN-DSM flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip San Diego to Des Moines Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $126 (one-way), $216 (round-trip).

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Best Flights from San Diego to Des Moines Today

Take a look at the list of non stop flights and flights with layovers from San Diego to Des Moines with the lowest price of $126. Take a look at the list of flights with layovers from San Diego to Des Moines from $126. There’re no direct flights. The fastest connecting flight – 5h 21m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $126 Find flight	15:10 San Diego San Diego	22:52 Des Moines Des Moines International Airport	5h 42m layover 1h 24m - Las Vegas	Spirit Airlines	NK3792 G42100
from $245 Find flight	08:30 San Diego San Diego	17:30 Des Moines Des Moines International Airport	7h 0m layover 2h 46m - Phoenix	Alaska Airlines	AS4324 AS4791
from $248 Find flight	16:11 San Diego San Diego	23:59 Des Moines Des Moines International Airport	5h 48m layover 1h 24m - Denver	United Airlines	UA682 UA4680
from $248 Find flight	13:35 San Diego San Diego	22:30 Des Moines Des Moines International Airport	6h 55m layover 1h 20m - Houston	United Airlines	UA1177 UA1823
from $248 Find flight	07:00 San Diego San Diego	16:11 Des Moines Des Moines International Airport	7h 11m layover 2h 57m - Denver	United Airlines	UA1365 UA2265
from $248 Find flight	11:20 San Diego San Diego	20:36 Des Moines Des Moines International Airport	7h 16m layover 3h 2m - Denver	United Airlines	UA264 UA1925
from $248 Find flight	12:13 San Diego San Diego	22:30 Des Moines Des Moines International Airport	8h 17m layover 2h 42m - Houston	United Airlines	UA1627 UA1823
from $248 Find flight	07:00 San Diego San Diego	17:53 Des Moines Des Moines International Airport	8h 53m layover 3h 9m - Chicago	United Airlines	UA1502 UA5504
from $248 Find flight	07:00 San Diego San Diego	17:54 Des Moines Des Moines International Airport	8h 54m layover 3h 9m - Chicago	United Airlines	UA1502 UA3569
from $157 Find flight	08:18 San Diego San Diego	22:52 Des Moines Des Moines International Airport	12h 34m layover 4h 4m - San Jose 2h 46m - Las Vegas	Spirit Airlines	NK1497 NK1371 G42100
from $253 Find flight	06:15 San Diego San Diego	16:11 Des Moines Des Moines International Airport	7h 56m layover 1h 31m - Los Angeles 1h 6m - Denver	United Airlines	UA4723 UA1810 UA2265
from $253 Find flight	10:15 San Diego San Diego	20:36 Des Moines Des Moines International Airport	8h 21m layover 1h 36m - Los Angeles 1h 25m - Denver	United Airlines	UA5249 UA493 UA1925
from $253 Find flight	10:15 San Diego San Diego	21:52 Des Moines Des Moines International Airport	9h 37m layover 1h 56m - Los Angeles 0h 47m - Chicago	United Airlines	UA5249 UA1027 UA630
from $253 Find flight	10:15 San Diego San Diego	21:52 Des Moines Des Moines International Airport	9h 37m layover 1h 20m - Los Angeles 1h 25m - Chicago	United Airlines	UA5249 UA1819 UA630
from $253 Find flight	12:03 San Diego San Diego	23:59 Des Moines Des Moines International Airport	9h 56m layover 0h 52m - San Francisco 2h 43m - Denver	United Airlines	UA375 UA1691 UA4680
from $253 Find flight	12:03 San Diego San Diego	23:59 Des Moines Des Moines International Airport	9h 56m layover 2h 12m - San Francisco 1h 23m - Denver	United Airlines	UA375 UA566 UA4680

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on January 15, 2025

Flight Schedule San Diego (California) to Des Moines (Iowa)

Full flight schedule will help you in detecting at what time planes fly from San Diego to Des Moines. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
07:00 — 16:11	07:00 — 10:28 UA1365 United Airlines San Diego — Denver 2h 57m stop 13:25 — 16:11 UA2265 United Airlines Denver — Des Moines	7h 11m including layover	Find flight from$248
07:00 — 17:53	07:00 — 13:11 UA1502 United Airlines San Diego — Chicago 3h 9m stop 16:20 — 17:53 UA5504 United Airlines Chicago — Des Moines	8h 53m including layover	Find flight from$248
11:10 — 21:23	11:10 — 17:10 UA714 United Airlines San Diego — Chicago 2h 40m stop 19:50 — 21:23 UA617 United Airlines Chicago — Des Moines	8h 13m including layover	Find flight from$345
11:20 — 20:36	11:15 — 14:43 UA264 United Airlines San Diego — Denver 3h 2m stop 17:50 — 20:34 UA1925 United Airlines Denver — Des Moines	7h 16m including layover	Find flight from$248
12:13 — 22:30	12:13 — 17:25 UA1627 United Airlines San Diego — Houston 2h 42m stop 20:07 — 22:30 UA1823 United Airlines Houston — Des Moines	8h 17m including layover	Find flight from$248
13:00 — 20:39	12:55 — 16:23 UA1374 United Airlines San Diego — Denver 1h 29m stop 17:50 — 20:34 UA1925 United Airlines Denver — Des Moines	5h 39m including layover	Find flight from$299
13:35 — 22:30	13:35 — 18:47 UA1177 United Airlines San Diego — Houston 1h 20m stop 20:07 — 22:30 UA1823 United Airlines Houston — Des Moines	6h 55m including layover	Find flight from$248
15:10 — 22:52	15:10 — 16:33 NK3792 Spirit Airlines San Diego — Las Vegas 1h 24m stop 17:57 — 22:52 G42100 Allegiant Air Las Vegas — Des Moines	5h 42m including layover	Find flight from$126
16:09 — 23:30	16:09 — 19:35 UA682 United Airlines San Diego — Denver 1h 3m stop 20:38 — 23:30 UA5445 United Airlines Denver — Des Moines	5h 21m including layover	Find flight from$299
16:11 — 23:59	16:10 — 19:38 UA682 United Airlines San Diego — Denver 1h 24m stop 21:03 — 23:59 UA4680 United Airlines Denver — Des Moines	5h 48m including layover	Find flight from$248
06:15 — 16:11	06:15 — 07:19 UA4723 United Airlines San Diego — Los Angeles 1h 31m stop 08:50 — 12:19 UA1810 United Airlines Los Angeles — Denver 1h 6m stop 13:25 — 16:11 UA2265 United Airlines Denver — Des Moines	7h 56m including layover	Find flight from$253
06:15 — 20:36	06:15 — 07:19 UA4723 United Airlines San Diego — Los Angeles 3h 56m stop 11:15 — 14:44 UA1260 United Airlines Los Angeles — Denver 3h 6m stop 17:50 — 20:36 UA1925 United Airlines Denver — Des Moines	12h 21m including layover	Find flight from$253
08:18 — 22:52	08:18 — 09:41 NK1497 Spirit Airlines San Diego — San Jose 4h 4m stop 13:45 — 15:11 NK1371 Spirit Airlines San Jose — Las Vegas 2h 46m stop 17:57 — 22:52 G42100 Allegiant Air Las Vegas — Des Moines	12h 34m including layover	Find flight from$157
08:18 — 22:52	08:18 — 09:41 NK1497 Spirit Airlines San Diego — San Jose 1h 10m stop 10:51 — 12:18 NK194 Spirit Airlines San Jose — Las Vegas 5h 39m stop 17:57 — 22:52 G42100 Allegiant Air Las Vegas — Des Moines	12h 34m including layover	Find flight from$157
10:15 — 20:36	10:15 — 11:19 UA5249 United Airlines San Diego — Los Angeles 1h 36m stop 12:55 — 16:25 UA493 United Airlines Los Angeles — Denver 1h 25m stop 17:50 — 20:36 UA1925 United Airlines Denver — Des Moines	8h 21m including layover	Find flight from$253
10:15 — 21:52	10:15 — 11:19 UA5249 United Airlines San Diego — Los Angeles 1h 56m stop 13:15 — 19:33 UA1027 United Airlines Los Angeles — Chicago 47m stop 20:20 — 21:52 UA630 United Airlines Chicago — Des Moines	9h 37m including layover	Find flight from$253
12:03 — 23:59	12:03 — 13:48 UA375 United Airlines San Diego — San Francisco 52m stop 14:40 — 18:20 UA1691 United Airlines San Francisco — Denver 2h 43m stop 21:03 — 23:59 UA4680 United Airlines Denver — Des Moines	9h 56m including layover	Find flight from$253
15:10 — 14:42 +1 day	15:10 — 16:33 NK3792 Spirit Airlines San Diego — Las Vegas 6h 12m stop 22:45 — 06:08 NK900 Spirit Airlines Las Vegas — Clearwater 6h 28m stop 12:36 — 14:42 G42070 Allegiant Air Clearwater — Des Moines	21h 32m including layover	Find flight from$270
20:51 — 10:38 +1 day	20:51 — 21:55 UA5636 United Airlines San Diego — Los Angeles 1h 58m stop 23:53 — 05:54 UA1832 United Airlines Los Angeles — Chicago 3h 6m stop 09:00 — 10:38 UA4481 United Airlines Chicago — Des Moines	11h 47m including layover	Find flight from$304
20:58 — 12:44 +1 day	20:58 — 22:23 NK1480 Spirit Airlines San Diego — Las Vegas 1h 22m stop 23:45 — 07:22 NK1853 Spirit Airlines Las Vegas — Sanford 3h 14m stop 10:36 — 12:44 G42080 Allegiant Air Sanford — Des Moines	13h 46m including layover	Find flight from$307

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on January 15, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from San Diego to Des Moines depends on and how to choose the most interesting flight option for you.

Distance between San Diego and Des Moines is 2295 miles. Time difference between the cities is 2h. Airplanes depart 06:15 to 20:58 from 11 San Diego airport and arrive 06:15 to 20:58 to 1 Des Moines airport. Average flight time is 10h 38m.

The fastest flight 5h 21m
Average flight time 10h 38m
The earliest flight 06:15
The latest flight 20:58
Distance 1427 ml

The cheapest months to travel to Des Moines are february (from 126 $), january (from 245 $), november (from 297 $).

The most expensive months are december (from 297 $), november (from 297 $), january (from 245 $).

What is the lowest airfare San Diego to Des Moines?

The cheapest plane ticket found by our users is $126. This airfare is for economy class on one-way NK3792 flight by Spirit Airlines for February 21, 2025 which leaves San Diego in San Diego at 15:10 am and arrives at Des Moines Des Moines International Airport at 22:52.

Economy class

$126

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Popular Airlines on the Route

The flight San Diego — Des Moines is served by 3 regular airlines and 1 low-cost airline. Most of the flights on this route are operated by Alaska Airlines - 1 departures per week at the price of from $ 245 . And the most expensive tickets are offered by United Airlines airline - from $ 533.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 48 flights with layovers on the route. The fastest connecting flight is UA682 by United Airlines takes 5h 21m and the cheapest is NK3792 by Spirit Airlines for $126.

AS - Alaska Airlines

from $245

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UA - United Airlines

from $248

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NK - Spirit Airlines

from $126

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See more connecting flights

Airports

You can fly from San Diego to Des Moines from 11 airports (San Diego, San Diego Regional, Gillespie Field, Golden Triangle Reg., El Cajon, Lowndes County, Miramar NAS, Montgomery Field, North Island NAS, Brown Field Municipal, AFB).

San Diego airports

San Diego-SAN

from $126
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San Diego Regional-USA

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Gillespie Field-SEE

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Golden Triangle Reg.-GTR

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El Cajon-CJN

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Lowndes County-UBS

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Miramar NAS-NKX

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Montgomery Field-MYF

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North Island NAS-NZY

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Brown Field Municipal-SDM

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AFB-CBM

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Des Moines airports

Des Moines International Airport-DSM

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Airplanes

There are flights to Des Moines from San Diego by 3 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from San Diego

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Top International Destinations from San Diego

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

San Diego — London

from $66

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from $60

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from $54

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San Diego — Amsterdam

from $65

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from $64

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How to book a plane ticket yourself?

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That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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