Cheap Flights from San Diego, CA to Louisville, KY from $139

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On Cheapflightsplus.com you will find 127 connecting flights from San Diego to Louisville. You can compare airfare deals from 5 airlines and multiple travel sites from $139, book and save on cheap plane tickets and last minute offers. Also check out SAN-SDF flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip San Diego to Louisville Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $139 (one-way), $238 (round-trip).

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Best Flights from San Diego to Louisville Today

Take a look at the list of non stop flights and flights with layovers from San Diego to Louisville with the lowest price of $139. Take a look at the list of flights with layovers from San Diego to Louisville from $139. There’re no direct flights. The fastest connecting flight – 6h 38m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $177 Find flight	17:49 San Diego San Diego	08:55+1 день Louisville Standiford Field	12h 6m layover 6h 41m - Minneapolis	Sun Country Airlines	SY408 SY1791
from $198 Find flight	07:24 San Diego San Diego	13:12+1 день Louisville Standiford Field	26h 48m layover 21h 24m - Minneapolis	Sun Country Airlines	SY1640 SY1791
from $209 Find flight	15:10 San Diego San Diego	14:38+1 день Louisville Standiford Field	20h 28m layover 15h 27m - Las Vegas	Spirit Airlines	NK3792 NK413
from $237 Find flight	12:52 San Diego San Diego	22:30 Louisville Standiford Field	6h 38m layover 1h 25m - Denver	United Airlines	UA1483 UA231
from $139 Find flight	15:10 San Diego San Diego	17:14+1 день Louisville Standiford Field	23h 4m layover 2h 14m - Las Vegas 13h 54m - Los Angeles	Spirit Airlines	NK3792 NK1495 NK468
from $139 Find flight	11:40 San Diego San Diego	17:14+1 день Louisville Standiford Field	26h 34m layover 5h 45m - Las Vegas 13h 54m - Los Angeles	Spirit Airlines	NK1480 NK1495 NK468
from $139 Find flight	09:09 San Diego San Diego	17:14+1 день Louisville Standiford Field	29h 5m layover 8h 16m - Las Vegas 13h 54m - Los Angeles	Spirit Airlines	NK1499 NK1495 NK468
from $159 Find flight	16:57 San Diego San Diego	15:36+1 день Louisville Standiford Field	19h 39m layover 3h 18m - Las Vegas 9h 45m - Los Angeles	Spirit Airlines	NK1157 NK1657 NK1029
from $162 Find flight	06:15 San Diego San Diego	11:44+1 день Louisville Standiford Field	26h 29m layover 6h 39m - Las Vegas 12h 42m - Fort Walton Beach	Spirit Airlines	NK1153 G4104 G43119
from $163 Find flight	18:50 San Diego San Diego	15:36+1 день Louisville Standiford Field	17h 46m layover 1h 24m - Las Vegas 9h 45m - Los Angeles	Spirit Airlines	NK1151 NK1657 NK1029
from $170 Find flight	13:00 San Diego San Diego	17:45+1 день Louisville Standiford Field	25h 45m layover 2h 37m - Las Vegas 16h 44m - Dallas	Spirit Airlines	NK1499 NK3712 NK2050
from $170 Find flight	11:40 San Diego San Diego	17:45+1 день Louisville Standiford Field	27h 5m layover 3h 59m - Las Vegas 16h 44m - Dallas	Spirit Airlines	NK1480 NK3712 NK2050
from $177 Find flight	21:25 San Diego San Diego	13:37+1 день Louisville Standiford Field	13h 12m layover 1h 20m - Las Vegas 5h 31m - Detroit	Spirit Airlines	NK1151 NK1252 NK1255
from $177 Find flight	16:57 San Diego San Diego	13:37+1 день Louisville Standiford Field	17h 40m layover 5h 51m - Las Vegas 5h 31m - Detroit	Spirit Airlines	NK1157 NK1252 NK1255
from $206 Find flight	16:57 San Diego San Diego	08:55+1 день Louisville Standiford Field	12h 58m layover 5h 40m - Las Vegas 1h 0m - Minneapolis	Spirit Airlines	NK1157 SY778 SY1791
from $207 Find flight	16:57 San Diego San Diego	14:57+1 день Louisville Standiford Field	19h 0m layover 4h 1m - Las Vegas 7h 14m - Clearwater	Spirit Airlines	NK1157 NK1683 G42636

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on July 13, 2025

Flight Schedule San Diego (California) to Louisville (Kentucky)

Full flight schedule will help you in detecting at what time planes fly from San Diego to Louisville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
06:35 — 17:27	06:35 — 12:54 UA2343 United Airlines San Diego — Chicago 2h 2m stop 14:56 — 17:27 UA5264 United Airlines Chicago — Louisville	7h 52m including layover	Find flight from$276
06:45 — 20:13	06:45 — 15:12 UA327 United Airlines San Diego — Newark 2h 33m stop 17:45 — 20:13 UA3531 United Airlines Newark — Louisville	10h 28m including layover	Find flight from$278
07:02 — 20:59	07:02 — 15:29 UA1115 United Airlines San Diego — Newark 3h 1m stop 18:30 — 20:59 UA3502 United Airlines Newark — Louisville	10h 57m including layover	Find flight from$276
07:24 — 13:12 +1 day	07:24 — 13:00 SY1640 Sun Country Airlines San Diego — Minneapolis 21h 24m stop 10:24 — 13:12 SY1791 Sun Country Airlines Minneapolis — Louisville	26h 48m including layover	Find flight from$198
08:05 — 20:00	08:05 — 13:24 UA2472 United Airlines San Diego — Houston 3h 11m stop 16:35 — 20:00 UA6151 United Airlines Houston — Louisville	8h 55m including layover	Find flight from$246
08:45 — 22:45	08:45 — 12:13 UA2476 United Airlines San Diego — Denver 5h 45m stop 17:58 — 22:45 UA1246 United Airlines Denver — Louisville	11h including layover	Find flight from$359
09:09 — 14:38 +1 day	09:09 — 10:31 NK1499 Spirit Airlines San Diego — Las Vegas 21h 29m stop 08:00 — 14:38 NK413 Spirit Airlines Las Vegas — Louisville	26h 29m including layover	Find flight from$209
10:15 — 20:00	10:15 — 15:39 UA2140 United Airlines San Diego — Houston 1h 1m stop 16:40 — 20:06 UA6151 United Airlines Houston — Louisville	6h 45m including layover	Find flight from$245
10:15 — 21:51	10:15 — 15:39 UA2140 United Airlines San Diego — Houston 2h 46m stop 18:25 — 21:51 UA6051 United Airlines Houston — Louisville	8h 36m including layover	Find flight from$245
11:17 — 22:30	11:17 — 14:45 UA1337 United Airlines San Diego — Denver 3h stop 17:45 — 22:30 UA231 United Airlines Denver — Louisville	8h 13m including layover	Find flight from$237
11:40 — 14:38 +1 day	11:40 — 13:02 NK1480 Spirit Airlines San Diego — Las Vegas 18h 58m stop 08:00 — 14:38 NK413 Spirit Airlines Las Vegas — Louisville	23h 58m including layover	Find flight from$209
12:45 — 22:45	12:45 — 16:13 UA1220 United Airlines San Diego — Denver 1h 45m stop 17:58 — 22:45 UA1246 United Airlines Denver — Louisville	7h including layover	Find flight from$245
12:52 — 22:30	12:52 — 16:20 UA1483 United Airlines San Diego — Denver 1h 25m stop 17:45 — 22:30 UA231 United Airlines Denver — Louisville	6h 38m including layover	Find flight from$237
14:05 — 22:14 +1 day	14:05 — 20:20 UA2628 United Airlines San Diego — Chicago 23h 20m stop 19:40 — 22:14 UA3551 United Airlines Chicago — Louisville	29h 9m including layover	Find flight from$304
14:05 — 09:57 +1 day	14:05 — 20:20 UA2628 United Airlines San Diego — Chicago 11h 5m stop 07:25 — 09:57 UA5574 United Airlines Chicago — Louisville	16h 52m including layover	Find flight from$337
15:10 — 14:38 +1 day	15:10 — 16:33 NK3792 Spirit Airlines San Diego — Las Vegas 15h 27m stop 08:00 — 14:38 NK413 Spirit Airlines Las Vegas — Louisville	20h 28m including layover	Find flight from$209
16:10 — 22:45 +1 day	16:10 — 19:38 UA682 United Airlines San Diego — Denver 22h 20m stop 17:58 — 22:45 UA2690 United Airlines Denver — Louisville	27h 35m including layover	Find flight from$324
17:30 — 22:14 +1 day	17:30 — 23:44 UA2486 United Airlines San Diego — Chicago 19h 56m stop 19:40 — 22:14 UA3551 United Airlines Chicago — Louisville	25h 44m including layover	Find flight from$304
17:49 — 08:55 +1 day	17:49 — 23:25 SY408 Sun Country Airlines San Diego — Minneapolis 6h 41m stop 06:06 — 08:55 SY1791 Sun Country Airlines Minneapolis — Louisville	12h 6m including layover	Find flight from$177
18:47 — 22:45 +1 day	18:47 — 22:15 UA519 United Airlines San Diego — Denver 19h 43m stop 17:58 — 22:45 UA2690 United Airlines Denver — Louisville	24h 58m including layover	Find flight from$324
21:20 — 12:07 +1 day	21:20 — 05:43 UA427 United Airlines San Diego — Newark 4h 2m stop 09:45 — 12:07 UA3678 United Airlines Newark — Louisville	11h 47m including layover	Find flight from$347
21:41 — 11:44 +1 day	21:41 — 06:00 UA1827 United Airlines San Diego — Newark 3h 25m stop 09:25 — 11:44 UA3496 United Airlines Newark — Louisville	11h 3m including layover	Find flight from$246
22:00 — 10:27 +1 day	21:50 — 05:49 UA2129 United Airlines San Diego — Washington D.C. 2h 41m stop 08:40 — 10:27 UA3473 United Airlines Washington D.C. — Louisville	9h 27m including layover	Find flight from$245
22:30 — 10:02 +1 day	22:30 — 04:37 UA2624 United Airlines San Diego — Chicago 2h 49m stop 07:26 — 10:02 UA3571 United Airlines Chicago — Louisville	8h 32m including layover	Find flight from$237

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on July 13, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from San Diego to Louisville depends on and how to choose the most interesting flight option for you.

Distance between San Diego and Louisville is 2898 miles. Time difference between the cities is 3h. Airplanes depart 06:15 to 23:00 from 11 San Diego airport and arrive 06:15 to 23:00 to 3 Louisville airports. Average flight time is 17h 7m.

The fastest flight 6h 38m
Average flight time 17h 7m
The earliest flight 06:15
The latest flight 23:00
Distance 1801 ml

The cheapest months to travel to Louisville are september (from 139 $), july (from 159 $), august (from 162 $).

The most expensive months are november (from 644 $), december (from 568 $), february (from 475 $).

What is the lowest airfare San Diego to Louisville?

The cheapest plane ticket found by our users is $139. This airfare is for economy class on one-way NK1480 flight by Spirit Airlines for September 27, 2025 which leaves San Diego in San Diego at 11:40 am and arrives at Louisville Standiford Field at 17:14.

Economy class

$139

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Business class

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First class

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Popular Airlines on the Route

The flight San Diego — Louisville is served by 5 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 5 departures per week at the price of from $ 282 . And the most expensive tickets are offered by United Airlines airline - from $ 543.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 127 flights with layovers on the route. The fastest connecting flight is UA1483 by United Airlines takes 6h 38m and the cheapest is NK1480 by Spirit Airlines for $139.

AS - Alaska Airlines

from $282

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SY - Sun Country Airlines

from $177

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MX - Mexicana

from $409

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UA - United Airlines

from $237

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NK - Spirit Airlines

from $139

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See more connecting flights

Airports

You can fly from San Diego to Louisville from 11 airports (San Diego, San Diego Regional, Gillespie Field, Golden Triangle Reg., El Cajon, Lowndes County, Miramar NAS, Montgomery Field, North Island NAS, Brown Field Municipal, AFB).

San Diego airports

San Diego-SAN

from $139
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San Diego Regional-USA

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Gillespie Field-SEE

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Golden Triangle Reg.-GTR

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El Cajon-CJN

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Lowndes County-UBS

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Miramar NAS-NKX

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Montgomery Field-MYF

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North Island NAS-NZY

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Brown Field Municipal-SDM

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AFB-CBM

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Louisville airports

Standiford Field-SDF

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Intercontinental-LJC

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Bowman Field-LOU

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Airplanes

There are flights to Louisville from San Diego by 5 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from San Diego

You may also consider searching for discounted plane tickets to some other popular places from San Diego within United States.

San Diego — Las Vegas

from $67

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San Diego — Seattle

from $56

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San Diego — New York

from $68

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San Diego — San Francisco

from $54

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San Diego — Denver

from $64

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San Diego — Phoenix

from $71

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San Diego — Chicago

from $57

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San Diego — Sacramento

from $76

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San Diego — Dallas

from $70

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San Diego — Boston

from $76

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Top International Destinations from San Diego

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

San Diego — San Jose

from $65

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San Diego — London

from $66

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San Diego — Vancouver

from $79

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San Diego — Tokyo

from $72

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San Diego — Cancun

from $72

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San Diego — Paris

from $79

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San Diego — Toronto

from $68

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San Diego — Rome

from $54

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San Diego — Madrid

from $65

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San Diego — Calgary

from $60

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How to book a plane ticket yourself?

Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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