Cheap Flights from San Diego, CA to Louisville, KY from $134

On Cheapflightsplus.com you will find 174 connecting flights from San Diego to Louisville. You can compare airfare deals from 6 airlines and multiple travel sites from $134, book and save on cheap plane tickets and last minute offers. Also check out SAN-SDF flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from San Diego to Louisville depends on and how to choose the most interesting flight option for you.

Distance between San Diego and Louisville is 2898 miles. Time difference between the cities is 3h. Airplanes depart 06:15 to 23:00 from 11 San Diego airport and arrive 06:15 to 23:00 to 3 Louisville airports. Average flight time is 18h 44m.

  • The fastest flight 6h 38m
  • Average flight time 18h 44m
  • The earliest flight 06:15
  • The latest flight 23:00
  • Distance 1801 ml

The cheapest months to travel to Louisville are september (from 134 $), july (from 154 $), august (from 157 $).

The most expensive months are december (from 549 $), february (from 459 $), august (from 157 $).

What is the lowest airfare San Diego to Louisville?

The cheapest plane ticket found by our users is $134. This airfare is for economy class on one-way NK1480 flight by Spirit Airlines for September 27, 2025 which leaves San Diego in San Diego at 11:40 am and arrives at Louisville Standiford Field at 17:14.

Economy class
$134
Find
Business class
?
Find
First class
?
Find

Flight Schedule San Diego (California) to Louisville (Kentucky)

07:24 — 13:12+1day
26h 48m flight time
Find flight
from$191
07:24 — 13:00 San Diego — Minneapolis
SY1640 Sun Country Airlines
21h 24m stop
10:24 — 13:12 Minneapolis — Louisville
SY1791 Sun Country Airlines
09:09 — 14:38+1day
26h 29m flight time
Find flight
from$202
09:09 — 10:31 San Diego — Las Vegas
NK1499 Spirit Airlines
21h 29m stop
08:00 — 14:38 Las Vegas — Louisville
NK413 Spirit Airlines
10:15 — 21:51
8h 36m flight time
Find flight
from$229
10:15 — 15:39 San Diego — Houston
UA2140 United Airlines
2h 46m stop
18:25 — 21:51 Houston — Louisville
UA6051 United Airlines
10:15 — 20:00
6h 45m flight time
Find flight
from$237
10:15 — 15:39 San Diego — Houston
UA2140 United Airlines
1h 1m stop
16:40 — 20:06 Houston — Louisville
UA6151 United Airlines
10:41 — 20:26
6h 45m flight time
Find flight
from$229
10:41 — 17:00 San Diego — Chicago
UA2677 United Airlines
58m stop
17:55 — 20:26 Chicago — Louisville
UA3598 United Airlines
11:17 — 22:30
8h 13m flight time
Find flight
from$229
11:17 — 14:45 San Diego — Denver
UA1337 United Airlines
3h stop
17:45 — 22:30 Denver — Louisville
UA231 United Airlines
11:27 — 22:45
8h 18m flight time
Find flight
from$229
11:17 — 14:45 San Diego — Denver
UA264 United Airlines
3h 3m stop
17:58 — 22:45 Denver — Louisville
UA2690 United Airlines
11:27 — 22:45
8h 18m flight time
Find flight
from$237
11:17 — 14:45 San Diego — Denver
UA264 United Airlines
3h 3m stop
17:58 — 22:45 Denver — Louisville
UA1246 United Airlines
11:40 — 14:38+1day
23h 58m flight time
Find flight
from$202
11:40 — 13:02 San Diego — Las Vegas
NK1480 Spirit Airlines
18h 58m stop
08:00 — 14:38 Las Vegas — Louisville
NK413 Spirit Airlines
11:58 — 21:51
6h 53m flight time
Find flight
from$229
11:58 — 17:22 San Diego — Houston
UA2237 United Airlines
1h 3m stop
18:25 — 21:51 Houston — Louisville
UA6051 United Airlines
12:45 — 22:45
7h flight time
Find flight
from$229
12:45 — 16:13 San Diego — Denver
UA1483 United Airlines
1h 45m stop
17:58 — 22:45 Denver — Louisville
UA2690 United Airlines
12:52 — 22:30
6h 38m flight time
Find flight
from$229
12:52 — 16:20 San Diego — Denver
UA1483 United Airlines
1h 25m stop
17:45 — 22:30 Denver — Louisville
UA231 United Airlines
15:10 — 14:38+1day
20h 28m flight time
Find flight
from$202
15:10 — 16:33 San Diego — Las Vegas
NK3792 Spirit Airlines
15h 27m stop
08:00 — 14:38 Las Vegas — Louisville
NK413 Spirit Airlines
17:49 — 08:55+1day
12h 6m flight time
Find flight
from$171
17:49 — 23:25 San Diego — Minneapolis
SY408 Sun Country Airlines
6h 41m stop
06:06 — 08:55 Minneapolis — Louisville
SY1791 Sun Country Airlines
22:30 — 10:02+1day
8h 32m flight time
Find flight
from$229
22:30 — 04:37 San Diego — Chicago
UA2624 United Airlines
2h 49m stop
07:26 — 10:02 Chicago — Louisville
UA3571 United Airlines
Full flight schedule will help you in detecting at what time planes fly from San Diego to Louisville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on November 7, 2025.

Popular Airlines on the Route

The flight San Diego — Louisville is served by 6 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 5 departures per week at the price of from $ 272 . And the most expensive tickets are offered by Hawaiian Airlines airline - from $ 615.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 174 flights with layovers on the route. The fastest connecting flight is UA1483 by United Airlines takes 6h 38m and the cheapest is NK1480 by Spirit Airlines for $134.

  • AS - Alaska Airlines
    from $272
    Find
  • SY - Sun Country Airlines
    from $171
    Find
  • HA - Hawaiian Airlines
    from $615
    Find
  • MX - Mexicana
    from $334
    Find
  • UA - United Airlines
    from $229
    Find
  • NK - Spirit Airlines
    from $134
    Find
See more connecting flights

Airports

You can fly from San Diego to Louisville from 11 airports (San Diego, San Diego Regional, Gillespie Field, Golden Triangle Reg., El Cajon, Lowndes County, Miramar NAS, Montgomery Field, North Island NAS, Brown Field Municipal, AFB).

San Diego airports

  • San Diego-SAN
    from $134
    Find
  • San Diego Regional-USA
    Find
  • Gillespie Field-SEE
    Find
  • Golden Triangle Reg.-GTR
    Find
  • El Cajon-CJN
    Find
  • Lowndes County-UBS
    Find
  • Miramar NAS-NKX
    Find
  • Montgomery Field-MYF
    Find
  • North Island NAS-NZY
    Find
  • Brown Field Municipal-SDM
    Find
  • AFB-CBM
    Find

Louisville airports

  • Standiford Field-SDF
    Find
  • Intercontinental-LJC
    Find
  • Bowman Field-LOU
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back