Cheap Flights from Louisville, KY to San Diego, CA from $118

On Cheapflightsplus.com you will find 170 connecting flights from Louisville to San Diego. You can compare airfare deals from 6 airlines and multiple travel sites from $118, book and save on cheap plane tickets and last minute offers. Also check out SDF-SAN flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Louisville to San Diego Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $118 (one-way), $202 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Louisville to San Diego. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
06:00 — 10:55
06:00 — 07:35 UA6358 United Airlines
Louisville — Washington D.C.
1h stop
08:35 — 10:55 UA1930 United Airlines
Washington D.C. — San Diego
7h 55m
including layover
Find flight
from$244
06:15 — 12:50
06:30 — 08:42 UA3594 United Airlines
Louisville — Newark
1h 25m stop
10:20 — 13:08 UA1826 United Airlines
Newark — San Diego
9h 35m
including layover
Find flight
from$240
07:20 — 10:55
07:05 — 08:38 UA6266 United Airlines
Louisville — Houston
41m stop
09:36 — 11:06 UA2491 United Airlines
Houston — San Diego
6h 35m
including layover
Find flight
from$240
07:20 — 13:54
07:20 — 08:50 UA6266 United Airlines
Louisville — Houston
3h 40m stop
12:30 — 13:54 UA2486 United Airlines
Houston — San Diego
9h 34m
including layover
Find flight
from$240
08:00 — 12:52
08:00 — 09:00 UA2354 United Airlines
Louisville — Denver
2h 28m stop
11:28 — 12:52 UA583 United Airlines
Denver — San Diego
7h 52m
including layover
Find flight
from$244
08:00 — 20:38
08:00 — 09:00 UA2354 United Airlines
Louisville — Denver
10h 14m stop
19:14 — 20:38 UA540 United Airlines
Denver — San Diego
15h 38m
including layover
Find flight
from$324
09:05 — 15:50
08:40 — 09:17 UA3653 United Airlines
Louisville — Chicago
3h 47m stop
14:06 — 16:28 UA2683 United Airlines
Chicago — San Diego
9h 45m
including layover
Find flight
from$240
09:31 — 12:57
09:31 — 10:30 UA2459 United Airlines
Louisville — Denver
1h 3m stop
11:33 — 12:57 UA1940 United Airlines
Denver — San Diego
6h 26m
including layover
Find flight
from$240
10:04 — 16:37
10:04 — 11:06 SY1792 Sun Country Airlines
Louisville — Minneapolis
3h 48m stop
14:54 — 16:37 SY407 Sun Country Airlines
Minneapolis — San Diego
9h 33m
including layover
Find flight
from$167
10:55 — 15:50
10:55 — 11:33 UA3520 United Airlines
Louisville — Chicago
1h 57m stop
13:30 — 15:50 UA2683 United Airlines
Chicago — San Diego
7h 55m
including layover
Find flight
from$240
11:10 — 19:07
11:10 — 13:22 UA3682 United Airlines
Louisville — Newark
3h 3m stop
16:36 — 19:18 UA1726 United Airlines
Newark — San Diego
10h 57m
including layover
Find flight
from$244
11:25 — 16:28
11:25 — 12:01 UA5482 United Airlines
Louisville — Chicago
2h 5m stop
14:06 — 16:28 UA2683 United Airlines
Chicago — San Diego
8h 3m
including layover
Find flight
from$261
12:45 — 19:09
12:44 — 14:59 UA3654 United Airlines
Louisville — Newark
1h 25m stop
16:25 — 19:09 UA1626 United Airlines
Newark — San Diego
9h 24m
including layover
Find flight
from$240
12:45 — 21:23
12:44 — 14:59 UA3654 United Airlines
Louisville — Newark
3h 30m stop
18:30 — 21:23 UA2342 United Airlines
Newark — San Diego
11h 38m
including layover
Find flight
from$240
13:59 — 18:20
14:10 — 14:50 UA4412 United Airlines
Louisville — Chicago
1h 19m stop
16:13 — 18:35 UA2417 United Airlines
Chicago — San Diego
7h 21m
including layover
Find flight
from$244
14:20 — 20:19
14:20 — 16:05 UA6026 United Airlines
Louisville — Washington D.C.
1h 45m stop
17:50 — 20:19 UA2054 United Airlines
Washington D.C. — San Diego
8h 59m
including layover
Find flight
from$240
14:50 — 20:40
14:50 — 16:28 UA6026 United Airlines
Louisville — Washington D.C.
1h 45m stop
18:13 — 20:40 UA2737 United Airlines
Washington D.C. — San Diego
8h 50m
including layover
Find flight
from$244
15:30 — 20:25
15:25 — 16:25 UA1510 United Airlines
Louisville — Denver
2h 31m stop
19:14 — 20:38 UA540 United Airlines
Denver — San Diego
7h 55m
including layover
Find flight
from$240
15:41 — 21:41
15:41 — 17:17 UA6310 United Airlines
Louisville — Houston
3h stop
20:17 — 21:41 UA2638 United Airlines
Houston — San Diego
9h
including layover
Find flight
from$240
17:52 — 22:02
17:52 — 18:39 UA4394 United Airlines
Louisville — Chicago
56m stop
19:35 — 22:02 UA734 United Airlines
Chicago — San Diego
7h 10m
including layover
Find flight
from$327
18:08 — 22:44
18:08 — 18:50 UA5318 United Airlines
Louisville — Chicago
1h 30m stop
20:20 — 22:44 UA1842 United Airlines
Chicago — San Diego
7h 36m
including layover
Find flight
from$244
18:08 — 22:44
18:08 — 18:50 UA5264 United Airlines
Louisville — Chicago
1h 30m stop
20:20 — 22:44 UA1842 United Airlines
Chicago — San Diego
7h 36m
including layover
Find flight
from$282
*Departure and arrival times - local. Updated on July 13, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Louisville to San Diego depends on and how to choose the most interesting flight option for you.

Distance between Louisville and San Diego is 2898 miles. Time difference between the cities is 3h. Airplanes depart 06:00 to 20:44 from 3 Louisville airports and arrive 06:00 to 20:44 to 11 San Diego airports. Average flight time is 14h 55m.

  • The fastest flight 6h 26m
  • Average flight time 14h 55m
  • The earliest flight 06:00
  • The latest flight 20:44
  • Distance 1801 ml

The cheapest months to travel to San Diego are july (from 118 $), october (from 136 $), august (from 159 $).

The most expensive months are november (from 479 $), september (from 337 $), december (from 334 $).

What is the lowest airfare Louisville to San Diego?

The cheapest plane ticket found by our users is $118. This airfare is for economy class on one-way NK1869 flight by Spirit Airlines for July 14, 2025 which leaves Standiford Field in Louisville at 18:26 am and arrives at San Diego San Diego at 23:00.

Economy class
$118
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Business class
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First class
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Popular Airlines on the Route

The flight Louisville — San Diego is served by 6 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 20 departures per week at the price of from $ 268 . And the most expensive tickets are offered by United Airlines airline - from $ 744.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 170 flights with layovers on the route. The fastest connecting flight is UA2459 by United Airlines takes 6h 26m and the cheapest is NK1869 by Spirit Airlines for $118.

  • AS - Alaska Airlines
    from $268
    Find
  • SY - Sun Country Airlines
    from $167
    Find
  • MX - Mexicana
    from $296
    Find
  • UA - United Airlines
    from $240
    Find
  • NK - Spirit Airlines
    from $118
    Find
  • G4 - Allegiant Air
    from $215
    Find
See more connecting flights

Airports

You can fly from Louisville to San Diego from 3 airports (Standiford Field, Intercontinental, Bowman Field).

Louisville airports

  • Standiford Field-SDF
    from $118
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  • Intercontinental-LJC
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  • Bowman Field-LOU
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San Diego airports

  • San Diego-SAN
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  • San Diego Regional-USA
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  • Gillespie Field-SEE
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  • Golden Triangle Reg.-GTR
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  • El Cajon-CJN
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  • Lowndes County-UBS
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  • Miramar NAS-NKX
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  • Montgomery Field-MYF
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  • North Island NAS-NZY
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  • Brown Field Municipal-SDM
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  • AFB-CBM
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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