Cheap Flights from Louisville, KY to San Diego, CA from $115

On Cheapflightsplus.com you will find 218 connecting flights from Louisville to San Diego. You can compare airfare deals from 6 airlines and multiple travel sites from $115, book and save on cheap plane tickets and last minute offers. Also check out SDF-SAN flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Louisville to San Diego depends on and how to choose the most interesting flight option for you.

Distance between Louisville and San Diego is 2898 miles. Time difference between the cities is 3h. Airplanes depart 05:03 to 20:44 from 3 Louisville airports and arrive 05:03 to 20:44 to 11 San Diego airports. Average flight time is 18h 14m.

  • The fastest flight 6h 26m
  • Average flight time 18h 14m
  • The earliest flight 05:03
  • The latest flight 20:44
  • Distance 1801 ml

The cheapest months to travel to San Diego are july (from 115 $), october (from 132 $), august (from 155 $).

The most expensive months are september (from 327 $), december (from 324 $), august (from 155 $).

What is the lowest airfare Louisville to San Diego?

The cheapest plane ticket found by our users is $115. This airfare is for economy class on one-way NK1869 flight by Spirit Airlines for July 14, 2025 which leaves Standiford Field in Louisville at 18:26 am and arrives at San Diego San Diego at 23:00.

Economy class
$115
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Business class
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First class
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Flight Schedule Louisville (Kentucky) to San Diego (California)

06:15 — 12:50
9h 35m flight time
Find flight
from$233
06:30 — 08:42 Louisville — Newark
UA3594 United Airlines
1h 25m stop
10:20 — 13:08 Newark — San Diego
UA1826 United Airlines
07:20 — 10:55
6h 35m flight time
Find flight
from$233
07:05 — 08:38 Louisville — Houston
UA6266 United Airlines
41m stop
09:36 — 11:06 Houston — San Diego
UA2491 United Airlines
07:20 — 13:54
9h 34m flight time
Find flight
from$233
07:20 — 08:50 Louisville — Houston
UA6266 United Airlines
3h 40m stop
12:30 — 13:54 Houston — San Diego
UA2486 United Airlines
09:05 — 15:50
9h 45m flight time
Find flight
from$233
08:40 — 09:17 Louisville — Chicago
UA3653 United Airlines
3h 47m stop
14:06 — 16:28 Chicago — San Diego
UA2683 United Airlines
09:31 — 12:57
6h 26m flight time
Find flight
from$233
09:31 — 10:30 Louisville — Denver
UA2459 United Airlines
1h 3m stop
11:33 — 12:57 Denver — San Diego
UA1940 United Airlines
09:31 — 15:01
8h 30m flight time
Find flight
from$233
09:31 — 10:30 Louisville — Denver
UA2459 United Airlines
3h 10m stop
13:40 — 15:01 Denver — San Diego
UA1302 United Airlines
09:40 — 13:54
7h 14m flight time
Find flight
from$233
09:35 — 11:05 Louisville — Houston
UA6108 United Airlines
1h 20m stop
12:50 — 14:11 Houston — San Diego
UA2486 United Airlines
09:55 — 15:03
8h 8m flight time
Find flight
from$233
09:55 — 11:36 Louisville — Washington D.C.
UA6279 United Airlines
1h 4m stop
12:40 — 15:03 Washington D.C. — San Diego
UA2029 United Airlines
10:04 — 16:37
9h 33m flight time
Find flight
from$162
10:04 — 11:06 Louisville — Minneapolis
SY1792 Sun Country Airlines
3h 48m stop
14:54 — 16:37 Minneapolis — San Diego
SY407 Sun Country Airlines
10:55 — 15:50
7h 55m flight time
Find flight
from$233
10:55 — 11:33 Louisville — Chicago
UA3520 United Airlines
1h 57m stop
13:30 — 15:50 Chicago — San Diego
UA2683 United Airlines
12:45 — 19:09
9h 24m flight time
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from$233
12:44 — 14:59 Louisville — Newark
UA3654 United Airlines
1h 25m stop
16:25 — 19:09 Newark — San Diego
UA1626 United Airlines
12:45 — 21:23
11h 38m flight time
Find flight
from$233
12:44 — 14:59 Louisville — Newark
UA3654 United Airlines
3h 30m stop
18:30 — 21:23 Newark — San Diego
UA2342 United Airlines
14:20 — 20:19
8h 59m flight time
Find flight
from$233
14:20 — 16:05 Louisville — Washington D.C.
UA6026 United Airlines
1h 45m stop
17:50 — 20:19 Washington D.C. — San Diego
UA2054 United Airlines
15:30 — 20:25
7h 55m flight time
Find flight
from$233
15:25 — 16:25 Louisville — Denver
UA1510 United Airlines
2h 31m stop
19:14 — 20:38 Denver — San Diego
UA540 United Airlines
15:41 — 21:41
9h flight time
Find flight
from$233
15:41 — 17:17 Louisville — Houston
UA6310 United Airlines
3h stop
20:17 — 21:41 Houston — San Diego
UA2638 United Airlines
Full flight schedule will help you in detecting at what time planes fly from Louisville to San Diego. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on November 5, 2025.

Popular Airlines on the Route

The flight Louisville — San Diego is served by 6 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 20 departures per week at the price of from $ 260 . And the most expensive tickets are offered by United Airlines airline - from $ 723.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 218 flights with layovers on the route. The fastest connecting flight is UA2459 by United Airlines takes 6h 26m and the cheapest is NK1869 by Spirit Airlines for $115.

  • AS - Alaska Airlines
    from $260
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  • SY - Sun Country Airlines
    from $162
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  • MX - Mexicana
    from $287
    Find
  • UA - United Airlines
    from $233
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  • NK - Spirit Airlines
    from $115
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  • G4 - Allegiant Air
    from $209
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See more connecting flights

Airports

You can fly from Louisville to San Diego from 3 airports (Standiford Field, Intercontinental, Bowman Field).

Louisville airports

  • Standiford Field-SDF
    from $115
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  • Intercontinental-LJC
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  • Bowman Field-LOU
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San Diego airports

  • San Diego-SAN
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  • San Diego Regional-USA
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  • Gillespie Field-SEE
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  • Golden Triangle Reg.-GTR
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  • El Cajon-CJN
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  • Lowndes County-UBS
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  • Miramar NAS-NKX
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  • Montgomery Field-MYF
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  • North Island NAS-NZY
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  • Brown Field Municipal-SDM
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  • AFB-CBM
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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