Cheap Flights from Prague to Chicago, IL from $340
On Cheapflightsplus.com you will find 1000 connecting flights from Prague to Chicago. You can compare airfare deals from 36 airlines and multiple travel sites from $340, book and save on cheap plane tickets and last minute offers. Also check out PRG-CHI flight schedule to find best flight time, convenient departure and arrival airports.
Flight Information
Below we will explain in detail what the flights cost on the destination from Prague to Chicago depends on and how to choose the most interesting flight option for you.
Distance between Prague and Chicago is 7290 miles. Time difference between the cities is 7h. Airplanes depart 06:00 to 23:45 from 2 Prague airports and arrive 06:00 to 23:45 to 7 Chicago airports. Average flight time is 25h 25m.
- The fastest flight 11h 25m
- Average flight time 25h 25m
- The earliest flight 06:00
- The latest flight 23:45
- Distance 4530 ml
Best Flights from Prague to Chicago Today
| Price | Departure | Arrival | Flight Duration | Airline | Flight |
|---|---|---|---|---|---|
| from $443 | 13:50 Prague Ruzyne | 18:15 Chicago O'Hare International | 11h 25m layover 1h 0m - Munich | Lufthansa | LH1691 LH434 |
| from $469 | 10:25 Prague Ruzyne | 15:55 Chicago O'Hare International | 12h 30m layover 1h 30m - London | British Airways | BA855 BA299 |
| from $340 | 11:55 Prague Ruzyne | 17:50+1 день Chicago O'Hare International | 36h 55m layover 23h 25m - Hagersten 1h 10m - Helsinki | Djibouti Airlines | D82621 AY808 AY9 |
| from $346 | 06:05 Prague Ruzyne | 19:00 Chicago O'Hare International | 19h 55m layover 2h 25m - Geneva 5h 15m - Dublin | Eurowings AG | EW4230 EI681 EI125 |
The cheapest months to travel to Chicago are august (from 340 $), october (from 346 $), september (from 406 $).
The most expensive months are january (from 714 $), november (from 704 $), december (from 690 $).
What is the lowest airfare Prague to Chicago?
The cheapest plane ticket found by our users is $340. This airfare is for economy class on one-way D82621 flight by Djibouti Airlines for August 27, 2025 which leaves Ruzyne in Prague at 11:55 am and arrives at Chicago O'Hare International at 17:50.
Flight Schedule Prague to Chicago (Illinois)
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Popular Airlines on the Route
The flight Prague — Chicago is served by 36 regular airlines and 8 low-cost airlines. Most of the flights on this route are operated by Condor Airlines - 3 departures per week at the price of from $ 718 . And the most expensive tickets are offered by Brussels Airlines airline - from $ 1085.
Direct flights
There’re no direct flights on this route. Try flights with stops.
Connecting Flights
There are 1000 flights with layovers on the route. The fastest connecting flight is LH1691 by Lufthansa takes 11h 25m and the cheapest is D82621 by Djibouti Airlines for $340.
- DE - Condor Airlinesfrom $718Find
- W9 - Wizz Air UKfrom $406Find
- VY - Vuelingfrom $470Find
- FI - Icelandairfrom $523Find
- LO - LOTfrom $573Find
- JU - Air Serbiafrom $443Find
- FR - Ryanairfrom $451Find
- LX - SWISS International Air Linesfrom $535Find
- UA - United Airlinesfrom $1045Find
- BT - airBalticfrom $637Find
- DY - Norwegianfrom $347Find
- SK - SASfrom $417Find
Airports
You can fly from Prague to Chicago from 2 airports (Ruzyne, Vodochody).
Prague airports
- Ruzyne-PRGfrom $340Find
- Vodochody-VODFind
Chicago airports
- O'Hare International-ORDFind
- Midway-MDWFind
- Dupage County-DPAFind
- Chicago FSS-CHIFind
- Merrill C Meigs (closed)-CGXFind
- Pal-Waukee-PWKFind
- Chicago NAS-NOHFind
Airplanes
There are flights to Chicago from Prague by 36 airlines that use 5 aircraft brands. They range from huge modern airplanes to small-sized.
- Bombardier CRJ 900from $443Find
- Airbus A321from $704Find
- Embraer 195from $966Find
- Airbus A320from $1 024Find
- Airbus A321NEOfrom $1 074Find
Top International Destinations from Prague
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
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How to book a plane ticket yourself?
- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
- Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
- Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
- Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
- That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
To find a plane ticket, please select dates.