Cheap Flights from Prague to Chicago, IL from $268
Return flight: Chicago – Prague
On Cheapflightsplus.com you will find 1000 connecting flights from Prague to Chicago. You can compare airfare deals from 36 airlines and multiple travel sites from $268, book and save on cheap plane tickets and last minute offers. Also check out PRG-CHI flight schedule to find best flight time, convenient departure and arrival airports.
Find One-Way and Round-Trip Prague to Chicago Flight Deals
To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights».
To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight.
Cheapest flights in November: $268 (one-way), $460 (round-trip).
Direct flights
Check prices for return flight
Best Flights from Prague to Chicago Today
Take a look at the list of non stop flights and flights with layovers from Prague to Chicago with the lowest price of $268. Take a look at the list of flights with layovers from Prague to Chicago from $268. There’re no direct flights. The fastest connecting flight – 11h 25m.
| Price | Departure | Arrival | Flight Duration | Airline | Flight |
|---|---|---|---|---|---|
| from $369 | 10:25 Prague Ruzyne | 15:55 Chicago O'Hare International | 12h 30m layover 1h 30m - London | British Airways | BA855 BA299 |
| from $393 | 11:50 Prague Ruzyne | 19:00 Chicago O'Hare International | 14h 10m layover 3h 15m - Dublin | Aer Lingus | EI643 EI125 |
| from $409 | 11:35 Prague Ruzyne | 17:25 Chicago O'Hare International | 12h 50m layover 1h 10m - Helsinki | Finnair | AY1222 AY9 |
| from $268 | 11:55 Prague Ruzyne | 17:50+1 день Chicago O'Hare International | 36h 55m layover 23h 25m - Hagersten 1h 10m - Helsinki | Djibouti Airlines | D82621 AY808 AY9 |
| from $273 | 06:05 Prague Ruzyne | 19:00 Chicago O'Hare International | 19h 55m layover 2h 25m - Geneva 5h 15m - Dublin | Eurowings AG | EW4230 EI681 EI125 |
| from $273 | 12:50 Prague Ruzyne | 17:50+1 день Chicago O'Hare International | 36h 0m layover 5h 45m - Oslo 17h 30m - Helsinki | Norwegian | DY1503 AY918 AY9 |
| from $281 | 15:45 Prague Ruzyne | 17:50+1 день Chicago O'Hare International | 33h 5m layover 1h 35m - Geneva 17h 35m - Helsinki | EasyJet | U21564 AY1534 AY9 |
| from $284 | 13:15 Prague Ruzyne | 19:00+1 день Chicago O'Hare International | 36h 45m layover 19h 15m - Geneva 5h 15m - Dublin | EasyJet | U21564 EI681 EI125 |
| from $285 | 20:00 Prague Ruzyne | 14:15+2 дня Chicago O'Hare International | 49h 15m layover 14h 55m - Geneva 21h 0m - Madrid | EasyJet | U21564 AY5629 AY5659 |
| from $288 | 09:25 Prague Ruzyne | 23:31+1 день Chicago O'Hare International | 45h 6m layover 19h 50m - Rome 6h 29m - Los Angeles | Aero Services Executive | W46136 N0411 NK3010 |
| from $320 | 17:00 Prague Ruzyne | 11:36+2 дня Chicago O'Hare International | 49h 36m layover 16h 50m - London 15h 20m - Los Angeles | Wizz Air UK | W92603 Z0711 NK466 |
| from $328 | 15:50 Prague Ruzyne | 17:25+1 день Chicago O'Hare International | 32h 35m layover 3h 35m - Hagersten 16h 40m - Helsinki | SAS | SK1768 AY820 AY9 |
| from $328 | 15:50 Prague Ruzyne | 17:25+1 день Chicago O'Hare International | 32h 35m layover 14h 20m - Hagersten 5h 55m - Helsinki | SAS | SK1768 AY802 AY9 |
| from $328 | 15:50 Prague Ruzyne | 17:25+1 день Chicago O'Hare International | 32h 35m layover 19h 0m - Hagersten 1h 15m - Helsinki | SAS | SK1768 AY804 AY9 |
| from $333 | 15:10 Prague Ruzyne | 11:36+2 дня Chicago O'Hare International | 51h 26m layover 18h 35m - London 15h 20m - Los Angeles | EasyJet | U28782 Z0711 NK466 |
| from $335 | 09:05 Prague Ruzyne | 17:50 Chicago O'Hare International | 15h 45m layover 1h 35m - Dusseldorf 1h 5m - Helsinki | Eurowings AG | EW9773 AY1392 AY9 |
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on July 01, 2025
Flight Schedule Prague to Chicago (Illinois)
Full flight schedule will help you in detecting at what time planes fly from Prague to Chicago. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
| Departure | Arrival | Flight Details | Flight Duration | Price |
|---|---|---|---|---|
|
07:20 — 15:55
|
06:55 — 08:05
BA853
British Airways
Prague — London
4h 40m stop
13:10 — 15:55
BA299
British Airways
London — Chicago
|
15h 35m including layover |
Find flight
from$369 |
|
|
07:20 — 18:15
|
07:20 — 08:30
BA853
British Airways
Prague — London
7h stop
15:30 — 18:15
BA297
British Airways
London — Chicago
|
17h 55m including layover |
Find flight
from$369 |
|
|
08:10 — 17:25
|
08:10 — 11:15
AY1228
Finnair
Prague — Helsinki
4h 45m stop
16:25 — 17:50
AY9
Finnair
Helsinki — Chicago
|
16h 15m including layover |
Find flight
from$409 |
|
|
08:10 — 17:25
|
08:10 — 11:15
BA6068
British Airways
Prague — Helsinki
4h 45m stop
16:25 — 17:50
BA6089
British Airways
Helsinki — Chicago
|
16h 15m including layover |
Find flight
from$411 |
|
|
09:40 — 18:15
|
09:40 — 10:45
W92601
Wizz Air UK
Prague — London
4h 45m stop
15:30 — 18:15
AY5537
Finnair
London — Chicago
|
15h 35m including layover |
Find flight
from$458 |
|
|
09:55 — 19:40
|
09:35 — 10:50
LO524
LOT
Prague — Warsaw
5h 35m stop
16:40 — 20:00
LO3
LOT
Warsaw — Chicago
|
16h 45m including layover |
Find flight
from$482 |
|
|
10:05 — 14:15
+1 day
|
10:05 — 13:05
QS1056
SmartWings
Prague — Madrid
22h 30m stop
11:35 — 14:15
AY5659
Finnair
Madrid — Chicago
|
35h 10m including layover |
Find flight
from$437 |
|
|
10:25 — 15:55
|
10:20 — 11:35
BA855
British Airways
Prague — London
1h 30m stop
13:10 — 15:55
BA299
British Airways
London — Chicago
|
12h 30m including layover |
Find flight
from$369 |
|
|
11:00 — 18:15
|
11:00 — 12:20
BA855
British Airways
Prague — London
3h 15m stop
15:45 — 18:45
BA297
British Airways
London — Chicago
|
14h 15m including layover |
Find flight
from$369 |
|
|
11:50 — 19:00
|
11:50 — 13:25
EI643
Aer Lingus
Prague — Dublin
3h 15m stop
16:40 — 19:00
EI125
Aer Lingus
Dublin — Chicago
|
14h 10m including layover |
Find flight
from$393 |
|
|
12:45 — 19:40
|
12:55 — 14:10
LO528
LOT
Prague — Warsaw
2h 40m stop
16:40 — 20:00
LO3
LOT
Warsaw — Chicago
|
13h 55m including layover |
Find flight
from$482 |
|
|
12:45 — 12:05
+1 day
|
12:45 — 14:00
LO528
LOT
Prague — Warsaw
19h 5m stop
09:05 — 12:05
LO31
LOT
Warsaw — Chicago
|
30h 20m including layover |
Find flight
from$495 |
|
|
13:40 — 12:50
+1 day
|
13:45 — 16:25
TP1241
TAP Portugal
Prague — Lisbon
17h 15m stop
13:15 — 16:30
TP243
TAP Portugal
Lisbon — Chicago
|
30h 10m including layover |
Find flight
from$452 |
|
|
14:00 — 21:15
|
14:00 — 15:55
FI537
Icelandair
Prague — Reykjavik
3h 40m stop
19:35 — 21:15
FI855
Icelandair
Reykjavik — Chicago
|
14h 15m including layover |
Find flight
from$412 |
|
|
14:15 — 09:40
+1 day
|
14:15 — 17:55
TK1774
Turkish Airlines
Prague — Istanbul
12h 35m stop
06:30 — 09:40
TK185
Turkish Airlines
Istanbul — Chicago
|
26h 25m including layover |
Find flight
from$548 |
|
|
15:35 — 18:15
+1 day
|
15:35 — 18:45
IB810
Iberia
Prague — Madrid
21h 55m stop
16:40 — 18:15
IB4230
Iberia
Madrid — Chicago
|
33h 40m including layover |
Find flight
from$485 |
|
|
15:35 — 14:15
+1 day
|
15:35 — 18:45
IB810
Iberia
Prague — Madrid
16h 50m stop
11:35 — 14:15
IB341
Iberia
Madrid — Chicago
|
29h 40m including layover |
Find flight
from$526 |
|
|
17:00 — 13:50
+1 day
|
17:00 — 18:05
W92603
Wizz Air UK
Prague — London
17h stop
11:05 — 13:50
BA295
British Airways
London — Chicago
|
27h 50m including layover |
Find flight
from$543 |
|
|
17:45 — 11:50
+1 day
|
21:25 — 22:35
BA861
British Airways
Prague — London
14h 20m stop
14:10 — 17:00
BA1542
British Airways
London — Chicago
|
25h 5m including layover |
Find flight
from$440 |
|
|
18:05 — 12:05
+1 day
|
18:05 — 19:20
LO522
LOT
Prague — Warsaw
13h 45m stop
09:05 — 12:05
LO31
LOT
Warsaw — Chicago
|
25h including layover |
Find flight
from$487 |
|
|
18:05 — 15:10
+1 day
|
18:05 — 19:20
LO522
LOT
Prague — Warsaw
16h 50m stop
12:10 — 15:10
LO1
LOT
Warsaw — Chicago
|
28h 5m including layover |
Find flight
from$487 |
|
|
19:30 — 17:25
+1 day
|
19:30 — 22:35
AY1224
Finnair
Prague — Helsinki
17h 25m stop
16:25 — 17:50
AY9
Finnair
Helsinki — Chicago
|
28h 55m including layover |
Find flight
from$409 |
|
|
19:40 — 14:15
+1 day
|
19:40 — 22:50
IB812
Iberia
Prague — Madrid
12h 45m stop
11:35 — 14:15
AY5659
Finnair
Madrid — Chicago
|
25h 35m including layover |
Find flight
from$446 |
|
|
20:45 — 13:55
+1 day
|
20:45 — 21:50
U22634
EasyJet
Prague — London
13h 20m stop
11:10 — 13:55
AY5535
Finnair
London — Chicago
|
24h 10m including layover |
Find flight
from$513 |
|
|
21:35 — 13:50
+1 day
|
18:55 — 20:05
BA857
British Airways
Prague — London
12h 30m stop
11:00 — 13:55
BA295
British Airways
London — Chicago
|
23h 15m including layover |
Find flight
from$369 |
|
|
21:35 — 15:55
+1 day
|
21:20 — 22:20
BA857
British Airways
Prague — London
14h 35m stop
13:10 — 15:55
BA299
British Airways
London — Chicago
|
25h 20m including layover |
Find flight
from$369 |
|
*Departure and arrival times - local. Updated on July 1, 2025
Flight Information
Below we will explain in detail what the flights cost on the destination from Prague to Chicago depends on and how to choose the most interesting flight option for you.
Distance between Prague and Chicago is 7290 miles. Time difference between the cities is 7h. Airplanes depart 06:00 to 23:45 from 2 Prague airports and arrive 06:00 to 23:45 to 7 Chicago airports. Average flight time is 25h 25m.
- The fastest flight 11h 25m
- Average flight time 25h 25m
- The earliest flight 06:00
- The latest flight 23:45
- Distance 4530 ml
The cheapest months to travel to Chicago are august (from 358 $), october (from 365 $), september (from 427 $).
The most expensive months are january (from 752 $), november (from 741 $), december (from 726 $).
What is the lowest airfare Prague to Chicago?
The cheapest plane ticket found by our users is $268. This airfare is for economy class on one-way D82621 flight by Djibouti Airlines for August 27, 2025 which leaves Ruzyne in Prague at 11:55 am and arrives at Chicago O'Hare International at 17:50.
Economy class
$268
Business class
?
First class
?
Popular Airlines on the Route
The flight Prague — Chicago is served by 36 regular airlines and 8 low-cost airlines. Most of the flights on this route are operated by Condor Airlines - 3 departures per week at the price of from $ 567 . And the most expensive tickets are offered by Brussels Airlines airline - from $ 855.
Direct flights
There’re no direct flights on this route. Try flights with stops.
Connecting Flights
There are 1000 flights with layovers on the route. The fastest connecting flight is LH1689 by Lufthansa takes 11h 25m and the cheapest is D82621 by Djibouti Airlines for $268.
- DE - Condor Airlinesfrom $567Find
- W9 - Wizz Air UKfrom $320Find
- VY - Vuelingfrom $370Find
- FI - Icelandairfrom $412Find
- LO - LOTfrom $452Find
- JU - Air Serbiafrom $350Find
- FR - Ryanairfrom $356Find
- LX - SWISS International Air Linesfrom $422Find
- UA - United Airlinesfrom $825Find
- BT - airBalticfrom $546Find
- DY - Norwegianfrom $273Find
- SK - SASfrom $328Find
See more connecting flights
Airports
You can fly from Prague to Chicago from 2 airports (Ruzyne, Vodochody).
Prague airports
- Ruzyne-PRGfrom $268Find
- Vodochody-VODFind
Chicago airports
- O'Hare International-ORDFind
- Midway-MDWFind
- Dupage County-DPAFind
- Chicago FSS-CHIFind
- Merrill C Meigs (closed)-CGXFind
- Pal-Waukee-PWKFind
- Chicago NAS-NOHFind
Airplanes
There are flights to Chicago from Prague by 36 airlines that use 5 aircraft brands. They range from huge modern airplanes to small-sized.
- Airbus A321from $555Find
- Embraer 195from $762Find
- Bombardier CRJ 900from $801Find
- Airbus A320from $807Find
- Airbus A321NEOfrom $847Find
Top International Destinations from Prague
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
- from $55Find
- from $56Find
- from $71Find
- from $66Find
- from $70Find
How to book a plane ticket yourself?
- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
- Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
- Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
- Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
- That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
To find a plane ticket, please select dates.