Cheap Flights from Panama City to Knoxville, TN from $304

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On Cheapflightsplus.com you will find 147 connecting flights from Panama City to Knoxville. You can compare airfare deals from 3 airlines and multiple travel sites from $304, book and save on cheap plane tickets and last minute offers. Also check out PTY-TYS flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Panama City to Knoxville Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $304 (one-way), $521 (round-trip).

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Best Flights from Panama City to Knoxville Today

Take a look at the list of non stop flights and flights with layovers from Panama City to Knoxville with the lowest price of $304. Take a look at the list of flights with layovers from Panama City to Knoxville from $304. There’re no direct flights. The fastest connecting flight – 10h 6m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $399 Find flight	16:40 Panama City Tocumen	13:58+1 день Knoxville Mc Ghee Tyson	21h 18m layover 14h 36m - Houston	United Airlines	UA1033 UA4887
from $487 Find flight	12:03 Panama City Tocumen	17:14+1 день Knoxville Mc Ghee Tyson	29h 11m layover 23h 50m - Miami	Compania Panamena de Aviacion	CM265 G43024
from $558 Find flight	08:55 Panama City Tocumen	20:03 Knoxville Mc Ghee Tyson	11h 8m layover 4h 26m - Houston	United Airlines	UA1249 UA4900
from $304 Find flight	15:34 Panama City Tocumen	20:32+1 день Knoxville Mc Ghee Tyson	28h 58m layover 13h 31m - Medellin 8h 33m - Sanford	Avianca	AV317 AV236 G43048
from $316 Find flight	18:30 Panama City Tocumen	20:32+1 день Knoxville Mc Ghee Tyson	26h 2m layover 12h 45m - Bogota 5h 53m - Sanford	Avianca	AV89 AV216 G43048
from $316 Find flight	18:30 Panama City Tocumen	22:09+1 день Knoxville Mc Ghee Tyson	27h 39m layover 12h 45m - Bogota 7h 30m - Sanford	Avianca	AV89 AV216 G43057
from $329 Find flight	20:05 Panama City Tocumen	18:55+1 день Knoxville Mc Ghee Tyson	22h 50m layover 4h 58m - San Salvador 11h 8m - Miami	Avianca	AV316 NK1032 G43025
from $330 Find flight	21:55 Panama City Tocumen	18:55+1 день Knoxville Mc Ghee Tyson	21h 0m layover 9h 20m - Bogota 4h 3m - Miami	Avianca	AV57 AV36 G43025
from $333 Find flight	18:30 Panama City Tocumen	14:28+2 дня Knoxville Mc Ghee Tyson	43h 58m layover 12h 45m - Bogota 23h 38m - Orlando	Avianca	AV89 AV216 G43044
from $341 Find flight	03:19 Panama City Tocumen	11:43+1 день Knoxville Mc Ghee Tyson	32h 24m layover 3h 51m - Bogota 21h 4m - Sanford	Avianca	AV41 AV216 G43028
from $342 Find flight	21:55 Panama City Tocumen	20:32+1 день Knoxville Mc Ghee Tyson	22h 37m layover 9h 20m - Bogota 5h 53m - Sanford	Avianca	AV57 AV216 G43048
from $342 Find flight	21:55 Panama City Tocumen	22:09+1 день Knoxville Mc Ghee Tyson	24h 14m layover 9h 20m - Bogota 7h 30m - Sanford	Avianca	AV57 AV216 G43057
from $342 Find flight	18:30 Panama City Tocumen	20:32+1 день Knoxville Mc Ghee Tyson	26h 2m layover 12h 0m - Bogota 6h 38m - Sanford	Avianca	AV89 AV28 G43048
from $342 Find flight	18:30 Panama City Tocumen	22:09+1 день Knoxville Mc Ghee Tyson	27h 39m layover 12h 0m - Bogota 8h 15m - Sanford	Avianca	AV89 AV28 G43057
from $352 Find flight	22:26 Panama City Tocumen	19:31+2 дня Knoxville Mc Ghee Tyson	45h 5m layover 13h 44m - Bogota 23h 47m - Sanford	Compania Panamena de Aviacion	CM430 NK1922 G41398
from $372 Find flight	13:30 Panama City Tocumen	23:31+1 день Knoxville Mc Ghee Tyson	34h 1m layover 23h 44m - San Jose 3h 56m - Miami	Avianca	AV642 NK338 G43025

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on December 21, 2024

Flight Schedule Panama City to Knoxville (Tennessee)

Full flight schedule will help you in detecting at what time planes fly from Panama City to Knoxville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
08:55 — 20:03	08:55 — 12:19 UA1249 United Airlines Panama City — Houston 4h 26m stop 16:45 — 20:03 UA4900 United Airlines Houston — Knoxville	11h 8m including layover	Find flight from$558
08:55 — 23:46	08:55 — 12:19 UA1249 United Airlines Panama City — Houston 8h 9m stop 20:28 — 23:46 UA4810 United Airlines Houston — Knoxville	14h 51m including layover	Find flight from$558
12:03 — 17:14 +1 day	12:03 — 15:17 CM265 Compania Panamena de Aviacion Panama City — Miami 23h 50m stop 15:07 — 17:14 G43024 Allegiant Air Miami — Knoxville	29h 11m including layover	Find flight from$487
12:04 — 07:52 +1 day	12:04 — 15:35 CM478 Compania Panamena de Aviacion Panama City — Sanford 14h 40m stop 06:15 — 07:52 G41402 Allegiant Air Sanford — Knoxville	19h 48m including layover	Find flight from$792
16:40 — 13:58 +1 day	16:40 — 20:04 UA1033 United Airlines Panama City — Houston 14h 36m stop 10:40 — 13:58 UA4887 United Airlines Houston — Knoxville	21h 18m including layover	Find flight from$399
16:40 — 18:08 +1 day	16:40 — 20:04 UA1033 United Airlines Panama City — Houston 18h 46m stop 14:50 — 18:08 UA4890 United Airlines Houston — Knoxville	25h 28m including layover	Find flight from$399
03:19 — 11:43 +1 day	03:19 — 04:54 AV41 Avianca Panama City — Bogota 3h 51m stop 08:45 — 13:00 AV216 Avianca Bogota — Sanford 21h 4m stop 10:04 — 11:43 G43028 Allegiant Air Sanford — Knoxville	32h 24m including layover	Find flight from$341
03:19 — 21:36	03:19 — 04:54 AV41 Avianca Panama City — Bogota 3h 51m stop 08:45 — 13:00 AV216 Avianca Bogota — Sanford 6h 58m stop 19:58 — 21:36 G41423 Allegiant Air Sanford — Knoxville	18h 17m including layover	Find flight from$375
07:43 — 13:05 +1 day	07:43 — 08:08 CM818 Compania Panamena de Aviacion Panama City — San Jose 6h 33m stop 14:41 — 19:05 NK1310 Spirit Airlines San Jose — Sanford 16h 22m stop 11:27 — 13:05 G43057 Allegiant Air Sanford — Knoxville	29h 22m including layover	Find flight from$388
07:43 — 17:33 +1 day	07:43 — 08:08 CM818 Compania Panamena de Aviacion Panama City — San Jose 6h 33m stop 14:41 — 19:05 NK1310 Spirit Airlines San Jose — Sanford 20h 50m stop 15:55 — 17:33 G43055 Allegiant Air Sanford — Knoxville	33h 50m including layover	Find flight from$394
09:27 — 20:32 +1 day	09:27 — 11:07 CM332 Compania Panamena de Aviacion Panama City — Bogota 2h 39m stop 13:46 — 18:05 NK1922 Spirit Airlines Bogota — Sanford 24h 48m stop 18:53 — 20:32 G43048 Allegiant Air Sanford — Knoxville	35h 5m including layover	Find flight from$406
09:27 — 11:43 +1 day	09:27 — 11:07 CM332 Compania Panamena de Aviacion Panama City — Bogota 2h 39m stop 13:46 — 18:05 NK1922 Spirit Airlines Bogota — Sanford 15h 59m stop 10:04 — 11:43 G43028 Allegiant Air Sanford — Knoxville	26h 16m including layover	Find flight from$413
11:20 — 13:05 +1 day	11:20 — 12:30 AV323 Avianca Panama City — Medellin 2h 16m stop 14:46 — 18:42 NK1352 Spirit Airlines Medellin — Sanford 16h 45m stop 11:27 — 13:05 G43057 Allegiant Air Sanford — Knoxville	25h 45m including layover	Find flight from$412
11:20 — 12:38 +1 day	11:20 — 12:30 AV323 Avianca Panama City — Medellin 2h 44m stop 15:14 — 18:50 NK236 Spirit Airlines Medellin — Miami 15h 39m stop 10:29 — 12:38 G41428 Allegiant Air Miami — Knoxville	25h 18m including layover	Find flight from$413
13:30 — 23:31 +1 day	13:30 — 13:45 AV642 Avianca Panama City — San Jose 23h 44m stop 13:29 — 17:30 NK338 Spirit Airlines San Jose — Miami 3h 56m stop 21:26 — 23:31 G43025 Allegiant Air Miami — Knoxville	34h 1m including layover	Find flight from$372
13:30 — 12:38 +1 day	13:30 — 13:45 AV642 Avianca Panama City — San Jose 12h 14m stop 01:59 — 05:57 NK1756 Spirit Airlines San Jose — Miami 4h 32m stop 10:29 — 12:38 G41428 Allegiant Air Miami — Knoxville	23h 8m including layover	Find flight from$405
15:34 — 20:32 +1 day	15:34 — 16:44 AV317 Avianca Panama City — Medellin 13h 31m stop 06:15 — 10:20 AV236 Avianca Medellin — Sanford 8h 33m stop 18:53 — 20:32 G43048 Allegiant Air Sanford — Knoxville	28h 58m including layover	Find flight from$304
15:34 — 22:09 +1 day	15:34 — 16:44 AV317 Avianca Panama City — Medellin 13h 31m stop 06:15 — 10:20 AV236 Avianca Medellin — Sanford 10h 10m stop 20:30 — 22:09 G43057 Allegiant Air Sanford — Knoxville	30h 35m including layover	Find flight from$304
18:30 — 20:32 +1 day	18:30 — 20:00 AV89 Avianca Panama City — Bogota 12h 45m stop 08:45 — 13:00 AV216 Avianca Bogota — Sanford 5h 53m stop 18:53 — 20:32 G43048 Allegiant Air Sanford — Knoxville	26h 2m including layover	Find flight from$316
18:30 — 22:09 +1 day	18:30 — 20:00 AV89 Avianca Panama City — Bogota 12h 45m stop 08:45 — 13:00 AV216 Avianca Bogota — Sanford 7h 30m stop 20:30 — 22:09 G43057 Allegiant Air Sanford — Knoxville	27h 39m including layover	Find flight from$316
20:05 — 18:55 +1 day	20:05 — 20:59 AV316 Avianca Panama City — San Salvador 4h 58m stop 01:59 — 05:40 NK1032 Spirit Airlines San Salvador — Miami 11h 8m stop 21:26 — 23:31 G43025 Allegiant Air Miami — Knoxville	22h 50m including layover	Find flight from$329
20:05 — 14:00 +2 days	20:05 — 20:59 AV316 Avianca Panama City — San Salvador 22h 46m stop 19:45 — 01:15 AV570 Avianca San Salvador — Newark 10h 40m stop 11:55 — 14:00 G41397 Allegiant Air Newark — Knoxville	41h 55m including layover	Find flight from$385
21:55 — 18:55 +1 day	21:55 — 23:25 AV57 Avianca Panama City — Bogota 9h 20m stop 08:45 — 12:45 AV36 Avianca Bogota — Miami 4h 3m stop 16:48 — 18:55 G43025 Allegiant Air Miami — Knoxville	21h including layover	Find flight from$330
21:55 — 20:32 +1 day	21:55 — 23:25 AV57 Avianca Panama City — Bogota 9h 20m stop 08:45 — 13:00 AV216 Avianca Bogota — Sanford 5h 53m stop 18:53 — 20:32 G43048 Allegiant Air Sanford — Knoxville	22h 37m including layover	Find flight from$342
22:26 — 19:31 +2 days	22:26 — 00:02 CM430 Compania Panamena de Aviacion Panama City — Bogota 13h 44m stop 13:46 — 18:05 NK1922 Spirit Airlines Bogota — Sanford 23h 47m stop 17:52 — 19:31 G41398 Allegiant Air Sanford — Knoxville	45h 5m including layover	Find flight from$352
22:26 — 14:28 +2 days	22:26 — 00:02 CM430 Compania Panamena de Aviacion Panama City — Bogota 13h 44m stop 13:46 — 18:05 NK1922 Spirit Airlines Bogota — Orlando 18h 33m stop 12:38 — 14:28 G43044 Allegiant Air Orlando — Knoxville	40h 2m including layover	Find flight from$369

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on December 21, 2024

Flight Information

Below we will explain in detail what the flights cost on the destination from Panama City to Knoxville depends on and how to choose the most interesting flight option for you.

Distance between Panama City and Knoxville is 3010 miles. Time difference between the cities is 0h. Airplanes depart 03:19 to 22:44 from 2 Panama City airports and arrive 03:19 to 22:44 to 1 Knoxville airport. Average flight time is 25h 1m.

The fastest flight 10h 6m
Average flight time 25h 1m
The earliest flight 03:19
The latest flight 22:44
Distance 1871 ml

The cheapest months to travel to Knoxville are january (from 304 $), december (from 372 $), february (from 375 $).

What is the lowest airfare Panama City to Knoxville?

The cheapest plane ticket found by our users is $304. This airfare is for economy class on one-way AV317 flight by Avianca for January 22, 2025 which leaves Tocumen in Panama City at 15:34 am and arrives at Knoxville Mc Ghee Tyson at 20:32.

Economy class

$304

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Business class

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First class

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Popular Airlines on the Route

The flight Panama City — Knoxville is served by 3 regular airlines . Most of the flights on this route are operated by Avianca - 86 departures per week at the price of from $ 304 . And the most expensive tickets are offered by Avianca airline - from $ 1798.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 147 flights with layovers on the route. The fastest connecting flight is CM393 by Compania Panamena de Aviacion takes 10h 6m and the cheapest is AV317 by Avianca for $304.

AV - Avianca

from $304

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CM - Compania Panamena de Aviacion

from $352

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UA - United Airlines

from $399

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Airports

You can fly from Panama City to Knoxville from 2 airports (Tocumen, Paitilla).

Panama City airports

Tocumen-PTY

from $304
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Paitilla-PAC

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Knoxville airports

Mc Ghee Tyson-TYS

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Airplanes

There are flights to Knoxville from Panama City by 3 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top International Destinations from Panama City

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Panama City — San Jose

from $68

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Panama City — San Jose

from $75

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Panama City — Denver

from $67

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Panama City — Dallas

from $69

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Panama City — Tampa

from $57

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Panama City — Phoenix

from $67

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Panama City — Houston

from $79

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Panama City — Las Vegas

from $73

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Panama City — New York

from $78

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Panama City — Chicago

from $73

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How to book a plane ticket yourself?

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