Cheap Flights from Panama City to Chicago, IL from $232

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On Cheapflightsplus.com you will find 85 connecting flights from Panama City to Chicago. You can compare airfare deals from 3 airlines and multiple travel sites from $232, book and save on cheap plane tickets and last minute offers. Also check out PTY-CHI flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Panama City to Chicago Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $232 (one-way), $398 (round-trip).

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Best Flights from Panama City to Chicago Today

Take a look at the list of non stop flights and flights with layovers from Panama City to Chicago with the lowest price of $232. Take a look at the list of flights with layovers from Panama City to Chicago from $232. There’re no direct flights. The fastest connecting flight – 8h 30m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $232 Find flight	03:19 Panama City Tocumen	12:15 Chicago O'Hare International	9h 56m layover 2h 6m - Bogota	Avianca	AV41 AV262
from $234 Find flight	21:55 Panama City Tocumen	12:15+1 день Chicago O'Hare International	15h 20m layover 7h 35m - Bogota	Avianca	AV57 AV262
from $386 Find flight	21:33 Panama City Tocumen	08:51+1 день Chicago O'Hare International	12h 18m layover 5h 49m - Miami	Compania Panamena de Aviacion	CM432 NK1838
from $456 Find flight	09:23 Panama City Tocumen	19:18 Chicago Midway	10h 55m layover 4h 37m - Miami	Compania Panamena de Aviacion	CM334 F92109
from $273 Find flight	18:30 Panama City Tocumen	08:51+1 день Chicago O'Hare International	15h 21m layover 3h 15m - Bogota 3h 15m - Miami	Avianca	AV89 AV8 NK1838
from $290 Find flight	13:30 Panama City Tocumen	09:55+1 день Chicago O'Hare International	21h 25m layover 12h 14m - San Jose 1h 43m - Miami	Avianca	AV642 NK1756 NK2
from $301 Find flight	15:34 Panama City Tocumen	12:15+1 день Chicago O'Hare International	21h 41m layover 4h 50m - Medellin 8h 31m - Bogota	Avianca	AV317 AV9569 AV262
from $301 Find flight	15:34 Panama City Tocumen	12:15+1 день Chicago O'Hare International	21h 41m layover 3h 54m - Medellin 9h 29m - Bogota	Avianca	AV317 AV9315 AV262
from $301 Find flight	15:34 Panama City Tocumen	12:15+1 день Chicago O'Hare International	21h 41m layover 4h 14m - Medellin 9h 7m - Bogota	Avianca	AV317 AV9355 AV262
from $301 Find flight	15:34 Panama City Tocumen	12:15+1 день Chicago O'Hare International	21h 41m layover 11h 51m - Medellin 1h 27m - Bogota	Avianca	AV317 AV9653 AV262
from $301 Find flight	15:34 Panama City Tocumen	12:15+1 день Chicago O'Hare International	21h 41m layover 2h 31m - Medellin 10h 48m - Bogota	Avianca	AV317 AV9553 AV262
from $301 Find flight	15:34 Panama City Tocumen	12:15+1 день Chicago O'Hare International	21h 41m layover 2h 19m - Medellin 11h 1m - Bogota	Avianca	AV317 AV8415 AV262
from $301 Find flight	15:34 Panama City Tocumen	12:15+1 день Chicago O'Hare International	21h 41m layover 5h 15m - Medellin 8h 6m - Bogota	Avianca	AV317 AV9335 AV262
from $301 Find flight	15:34 Panama City Tocumen	12:15+1 день Chicago O'Hare International	21h 41m layover 1h 45m - Medellin 11h 36m - Bogota	Avianca	AV317 AV9375 AV262
from $301 Find flight	15:34 Panama City Tocumen	12:15+1 день Chicago O'Hare International	21h 41m layover 2h 59m - Medellin 10h 20m - Bogota	Avianca	AV317 AV9261 AV262
from $323 Find flight	03:19 Panama City Tocumen	00:58+1 день Chicago O'Hare International	22h 39m layover 7h 56m - Bogota 5h 19m - San Juan	Avianca	AV41 AV258 NK492

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on February 23, 2025

Flight Schedule Panama City to Chicago (Illinois)

Full flight schedule will help you in detecting at what time planes fly from Panama City to Chicago. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
03:19 — 12:15	03:19 — 04:54 AV41 Avianca Panama City — Bogota 2h 6m stop 07:00 — 12:15 AV262 Avianca Bogota — Chicago	9h 56m including layover	Find flight from$232
07:21 — 20:25	07:21 — 11:30 UA7123 United Airlines Panama City — Los Angeles 2h 46m stop 14:15 — 20:25 UA2487 United Airlines Los Angeles — Chicago	14h 4m including layover	Find flight from$1642
08:01 — 19:18	08:01 — 11:17 CM226 Compania Panamena de Aviacion Panama City — Miami 5h 59m stop 17:21 — 19:36 F92109 Frontier Airlines Miami — Chicago	12h 17m including layover	Find flight from$400
08:55 — 17:06	08:55 — 12:19 UA1249 United Airlines Panama City — Houston 2h 1m stop 14:20 — 17:06 UA2097 United Airlines Houston — Chicago	9h 11m including layover	Find flight from$896
09:23 — 19:18	09:23 — 12:32 CM334 Compania Panamena de Aviacion Panama City — Miami 4h 37m stop 17:21 — 19:36 F92109 Frontier Airlines Miami — Chicago	10h 55m including layover	Find flight from$456
10:00 — 08:47 +1 day	10:00 — 15:17 UA727 United Airlines Panama City — Newark 15h 43m stop 07:00 — 08:47 UA1215 United Airlines Newark — Chicago	23h 47m including layover	Find flight from$896
10:00 — 11:52 +1 day	10:00 — 15:17 UA727 United Airlines Panama City — Newark 18h 54m stop 10:11 — 11:52 UA1525 United Airlines Newark — Chicago	26h 52m including layover	Find flight from$896
16:40 — 10:09 +1 day	16:40 — 20:04 UA1033 United Airlines Panama City — Houston 11h 16m stop 07:20 — 10:09 UA2182 United Airlines Houston — Chicago	18h 29m including layover	Find flight from$896
16:40 — 11:23 +1 day	16:40 — 20:04 UA1033 United Airlines Panama City — Houston 12h 36m stop 08:40 — 11:23 UA215 United Airlines Houston — Chicago	19h 43m including layover	Find flight from$896
18:30 — 12:15 +1 day	18:30 — 20:00 AV89 Avianca Panama City — Bogota 11h stop 07:00 — 12:15 AV262 Avianca Bogota — Chicago	18h 45m including layover	Find flight from$234
19:04 — 04:37 +1 day	19:03 — 22:05 CM188 Compania Panamena de Aviacion Panama City — Mexico City 2h 35m stop 00:40 — 04:37 Y4700 Volaris Mexico City — Chicago	10h 33m including layover	Find flight from$631
21:55 — 12:15 +1 day	21:55 — 23:25 AV57 Avianca Panama City — Bogota 7h 35m stop 07:00 — 12:15 AV262 Avianca Bogota — Chicago	15h 20m including layover	Find flight from$234
22:29 — 09:42 +1 day	22:29 — 03:13 UA7066 United Airlines Panama City — Washington D.C. 5h 9m stop 08:25 — 09:44 UA2440 United Airlines Washington D.C. — Chicago	12h 13m including layover	Find flight from$1643
03:19 — 08:51 +1 day	03:19 — 04:54 AV41 Avianca Panama City — Bogota 2h 51m stop 07:45 — 11:40 AV126 Avianca Bogota — Miami 18h 50m stop 06:30 — 08:51 NK1838 Spirit Airlines Miami — Chicago	30h 32m including layover	Find flight from$273
07:43 — 00:59 +1 day	07:43 — 08:08 CM818 Compania Panamena de Aviacion Panama City — San Jose 6h 33m stop 12:23 — 16:42 NK1310 Spirit Airlines San Jose — Orlando 3h 54m stop 07:30 — 09:54 F93043 Frontier Airlines Orlando — Chicago	18h 16m including layover	Find flight from$361
09:46 — 09:13 +1 day	09:46 — 11:01 CM452 Compania Panamena de Aviacion Panama City — Cartagena de Indias 3h 39m stop 14:40 — 18:05 NK1707 Spirit Airlines Cartagena de Indias — Orlando 13h 20m stop 07:25 — 09:13 F91457 Frontier Airlines Orlando — Chicago	24h 27m including layover	Find flight from$428
11:20 — 12:15 +1 day	11:20 — 12:30 AV323 Avianca Panama City — Medellin 2h 57m stop 15:27 — 16:27 AV9311 Avianca Medellin — Bogota 14h 33m stop 07:00 — 12:15 AV262 Avianca Bogota — Chicago	25h 55m including layover	Find flight from$301
11:20 — 12:15 +1 day	11:20 — 12:30 AV323 Avianca Panama City — Medellin 5h 59m stop 18:29 — 19:24 AV9375 Avianca Medellin — Bogota 11h 36m stop 07:00 — 12:15 AV262 Avianca Bogota — Chicago	25h 55m including layover	Find flight from$301
13:30 — 09:55 +1 day	13:30 — 13:45 AV642 Avianca Panama City — San Jose 12h 14m stop 01:56 — 05:50 NK1756 Spirit Airlines San Jose — Miami 1h 43m stop 12:56 — 15:16 NK2 Spirit Airlines Miami — Chicago	21h 25m including layover	Find flight from$290
15:34 — 12:15 +1 day	15:34 — 16:44 AV317 Avianca Panama City — Medellin 4h 50m stop 21:34 — 22:29 AV9569 Avianca Medellin — Bogota 8h 31m stop 07:00 — 12:15 AV262 Avianca Bogota — Chicago	21h 41m including layover	Find flight from$301
15:34 — 12:15 +1 day	15:34 — 16:44 AV317 Avianca Panama City — Medellin 3h 54m stop 20:38 — 21:31 AV9315 Avianca Medellin — Bogota 9h 29m stop 07:00 — 12:15 AV262 Avianca Bogota — Chicago	21h 41m including layover	Find flight from$301
18:30 — 08:51 +1 day	18:30 — 20:00 AV89 Avianca Panama City — Bogota 3h 15m stop 23:15 — 03:15 AV8 Avianca Bogota — Miami 3h 15m stop 06:30 — 08:51 NK1838 Spirit Airlines Miami — Chicago	15h 21m including layover	Find flight from$273
20:05 — 15:53 +1 day	20:05 — 20:59 AV316 Avianca Panama City — San Salvador 10h 41m stop 07:40 — 11:30 AV440 Avianca San Salvador — Dallas 2h 1m stop 10:12 — 12:32 F91888 Frontier Airlines Dallas — Chicago	20h 48m including layover	Find flight from$355
21:55 — 20:44 +1 day	21:55 — 23:25 AV57 Avianca Panama City — Bogota 8h 20m stop 07:45 — 11:40 AV214 Avianca Bogota — San Juan 6h 1m stop 17:41 — 20:44 NK1531 Spirit Airlines San Juan — Chicago	23h 49m including layover	Find flight from$323

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on February 23, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Panama City to Chicago depends on and how to choose the most interesting flight option for you.

Distance between Panama City and Chicago is 3737 miles. Time difference between the cities is 1h. Airplanes depart 03:19 to 22:29 from 2 Panama City airports and arrive 03:19 to 22:29 to 7 Chicago airports. Average flight time is 18h 29m.

The fastest flight 8h 30m
Average flight time 18h 29m
The earliest flight 03:19
The latest flight 22:29
Distance 2323 ml

The cheapest months to travel to Chicago are november (from 232 $), january (from 234 $), february (from 234 $).

The most expensive months are december (from 262 $), february (from 234 $), january (from 234 $).

What is the lowest airfare Panama City to Chicago?

The cheapest plane ticket found by our users is $232. This airfare is for economy class on one-way AV41 flight by Avianca for February 21, 2025 which leaves Tocumen in Panama City at 03:19 am and arrives at Chicago O'Hare International at 12:15.

Economy class

$232

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Business class

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First class

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Popular Airlines on the Route

The flight Panama City — Chicago is served by 3 regular airlines . Most of the flights on this route are operated by Avianca - 44 departures per week at the price of from $ 232 . And the most expensive tickets are offered by United Airlines airline - from $ 3082.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 85 flights with layovers on the route. The fastest connecting flight is UA1031 by United Airlines takes 8h 30m and the cheapest is AV41 by Avianca for $232.

AV - Avianca

from $232

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CM - Compania Panamena de Aviacion

from $338

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UA - United Airlines

from $896

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Airports

You can fly from Panama City to Chicago from 2 airports (Tocumen, Paitilla).

Panama City airports

Tocumen-PTY

from $232
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Paitilla-PAC

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Chicago airports

O'Hare International-ORD

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Midway-MDW

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Dupage County-DPA

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Chicago FSS-CHI

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Merrill C Meigs (closed)-CGX

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Pal-Waukee-PWK

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Chicago NAS-NOH

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Airplanes

There are flights to Chicago from Panama City by 3 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top International Destinations from Panama City

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Panama City — San Jose

from $68

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Panama City — San Jose

from $75

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Panama City — Denver

from $67

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Panama City — Dallas

from $69

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Panama City — Tampa

from $57

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Panama City — Phoenix

from $67

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Panama City — Houston

from $79

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Panama City — Las Vegas

from $73

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Panama City — New York

from $78

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Panama City — Chicago

from $73

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How to book a plane ticket yourself?

Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
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That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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