Cheap Flights from Panama City to Chicago, IL from $73

Return flight: Chicago – Panama City

On you will find 2 direct and 39 connecting flights from Panama City to Chicago. You can compare airfare deals from 4 airlines and multiple travel sites from $556, book and save on cheap plane tickets and last minute offers. Also check out PTY-CHI flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Panama City to Chicago Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $73 (one-way), $125 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Panama City to Chicago. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
17:56 — 23:35
17:56 — 23:35 CM235 Compania Panamena de Aviacion
Panama City — Chicago
5h 39m
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12:30 — 22:35
12:30 — 16:45 UA2417 United Airlines
Panama City — Houston
3h 15m stop
20:00 — 22:35 UA1611 United Airlines
Houston — Chicago
10h 5m
including layover
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22:00 — 05:11
+2 days
22:00 — 02:00 CM4138 Compania Panamena de Aviacion
Panama City — Mexico City
22h 50m stop
00:50 — 05:11 Y4954 Volaris
Mexico City — Chicago
31h 11m
including layover
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05:50 — 17:08
05:50 — 06:50 AV316 Avianca
Panama City — San Salvador
1h 15m stop
08:05 — 12:05 AV368 Avianca
San Salvador — Houston
2h 15m stop
14:20 — 17:08 UA1899 United Airlines
Houston — Chicago
11h 18m
including layover
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11:22 — 12:25
+1 day
11:22 — 14:52 CM4308 Compania Panamena de Aviacion
Panama City — Santo Domingo
14h 8m stop
05:00 — 07:09 AA1154 American Airlines
Santo Domingo — Miami
2h 56m stop
10:05 — 12:25 AA2796 American Airlines
Miami — Chicago
25h 3m
including layover
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18:50 — 14:55
+2 days
18:50 — 12:15 KL758 KLM
Panama City — Amsterdam
9h 50m stop
22:05 — 22:45 FR3007 Ryanair
Amsterdam — Dublin
13h 55m stop
12:40 — 14:55 EI123 Aer Lingus
Dublin — Chicago
44h 5m
including layover
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*Departure and arrival times - local. Updated on June 7, 2023

Flight Information

Below we will explain in detail what the flights cost on the destination from Panama City to Chicago depends on and how to choose the most interesting flight option for you.

Distance between Panama City and Chicago is 3737 miles. Time difference between the cities is 1h. Airplanes depart 05:50 to 22:10 from 2 Panama City airports and arrive 05:50 to 22:10 to 7 Chicago airports. Average flight time is 5h 39m.

  • The fastest flight 5h 39m
  • Average flight time 5h 39m
  • The earliest flight 05:50
  • The latest flight 22:10
  • Distance 2323 ml

What is the lowest airfare Panama City to Chicago?

The cheapest plane ticket found by our users is $556. This airfare is for economy class on one-way CM4308 flight by Compania Panamena de Aviacion for August 21, 2020 which leaves Tocumen in Panama City at 11:22 am and arrives at Chicago O'Hare International at 12:25.

Economy class
Business class
First class

Popular Airlines on the Route

The flight Panama City — Chicago is served by 4 regular airlines . Most of the flights on this route are operated by KLM - 8 departures per week at the price of from $ 1661 . And the most expensive tickets are offered by Compania Panamena de Aviacion airline - from $ 2346.

Direct flights

There are 2 nonstop flights on the route. The fastest direct flight is CM235 by Compania Panamena de Aviacion takes 5h 39m and the cheapest is CM4308 by Compania Panamena de Aviacion for $575.

  • CM - Compania Panamena de Aviacion
    from $575
  • UA - United Airlines
    from $1312
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Connecting Flights

There are 39 flights with layovers on the route. The fastest connecting flight is UA2417 by United Airlines takes 10h 5m and the cheapest is CM4308 by Compania Panamena de Aviacion for $556.

  • KL - KLM
    from $1661
  • AV - Avianca
    from $907
  • CM - Compania Panamena de Aviacion
    from $556
  • UA - United Airlines
    from $820
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You can fly from Panama City to Chicago from 2 airports (Tocumen, Paitilla).

Panama City airports

  • Tocumen-PTY
    from $556
  • Paitilla-PAC

Chicago airports

  • O'Hare International-ORD
  • Midway-MDW
  • Dupage County-DPA
  • Chicago FSS-CHI
  • Merrill C Meigs (closed)-CGX
  • Pal-Waukee-PWK
  • Chicago NAS-NOH

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.