Cheap Flights from Des Moines, IA to Myrtle Beach, SC from $131
On Cheapflightsplus.com you will find 52 connecting flights from Des Moines to Myrtle Beach. You can compare airfare deals from 2 airlines and multiple travel sites from $131, book and save on cheap plane tickets and last minute offers. Also check out DSM-MYR flight schedule to find best flight time, convenient departure and arrival airports.
Find One-Way and Round-Trip Des Moines to Myrtle Beach Flight Deals
To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights».
To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight.
Cheapest flights in November: $131 (one-way), $225 (round-trip).
Direct flights
Check prices for return flight
Best Flights from Des Moines to Myrtle Beach Today
Take a look at the list of non stop flights and flights with layovers from Des Moines to Myrtle Beach with the lowest price of $131. Take a look at the list of flights with layovers from Des Moines to Myrtle Beach from $131. There’re no direct flights. The fastest connecting flight – 8h 19m.
| Price | Departure | Arrival | Flight Duration | Airline | Flight |
|---|---|---|---|---|---|
| from $131 | 07:30 Des Moines Des Moines International Airport | 17:58 Myrtle Beach AFB | 9h 28m layover 4h 53m - Newark | Allegiant Air | G4431 NK943 |
| from $201 | 07:30 Des Moines Des Moines International Airport | 18:13 Myrtle Beach AFB | 9h 43m layover 5h 4m - Newark | Allegiant Air | G4442 NK943 |
| from $216 | 09:00 Des Moines Des Moines International Airport | 20:04 Myrtle Beach AFB | 10h 4m layover 5h 49m - Orlando | Allegiant Air | G4464 NK136 |
| from $357 | 08:57 Des Moines Des Moines International Airport | 18:16 Myrtle Beach AFB | 8h 19m layover 4h 13m - Orlando | Allegiant Air | G41341 NK136 |
| from $376 | 06:00 Des Moines Des Moines International Airport | 17:17 Myrtle Beach AFB | 10h 17m layover 6h 1m - Orlando | Allegiant Air | G4444 NK136 |
| from $384 | 07:00 Des Moines Des Moines International Airport | 16:30 Myrtle Beach AFB | 8h 30m layover 3h 33m - Miami | Allegiant Air | G4434 NK3647 |
| from $256 | 15:35 Des Moines Des Moines International Airport | 10:10+1 день Myrtle Beach AFB | 17h 35m layover 5h 1m - Las Vegas 1h 48m - Hartford | Allegiant Air | G4451 MX527 MX558 |
| from $286 | 15:35 Des Moines Des Moines International Airport | 08:10+1 день Myrtle Beach AFB | 15h 35m layover 4h 56m - Las Vegas 1h 19m - Orlando | Allegiant Air | G4451 NK903 NK292 |
| from $417 | 06:00 Des Moines Des Moines International Airport | 20:40 Myrtle Beach AFB | 13h 40m layover 5h 44m - Orlando 1h 25m - Atlantic City | Allegiant Air | G4444 NK2155 NK1918 |
| from $425 | 07:00 Des Moines Des Moines International Airport | 20:40 Myrtle Beach AFB | 12h 40m layover 4h 26m - Miami 0h 55m - Atlantic City | Allegiant Air | G4434 NK1917 NK1918 |
| from $518 | 15:23 Des Moines Des Moines International Airport | 12:56+1 день Myrtle Beach AFB | 20h 33m layover 4h 44m - Chicago 10h 12m - Newark | United Airlines | UA1568 UA2371 UA3474 |
| from $526 | 18:54 Des Moines Des Moines International Airport | 12:56+1 день Myrtle Beach AFB | 17h 2m layover 1h 10m - Chicago 10h 12m - Newark | United Airlines | UA3433 UA2371 UA3474 |
| from $568 | 18:54 Des Moines Des Moines International Airport | 12:56+1 день Myrtle Beach AFB | 17h 2m layover 9h 35m - Chicago 1h 45m - Newark | United Airlines | UA3433 UA1658 UA3474 |
| from $568 | 15:23 Des Moines Des Moines International Airport | 12:56+1 день Myrtle Beach AFB | 20h 33m layover 13h 9m - Chicago 1h 45m - Newark | United Airlines | UA1568 UA1658 UA3474 |
| from $568 | 08:00 Des Moines Des Moines International Airport | 12:56+1 день Myrtle Beach AFB | 27h 56m layover 12h 8m - Chicago 10h 12m - Newark | United Airlines | UA1363 UA2371 UA3474 |
| from $582 | 18:54 Des Moines Des Moines International Airport | 11:56+1 день Myrtle Beach AFB | 16h 2m layover 1h 13m - Chicago 9h 17m - Newark | United Airlines | UA1807 UA1791 UA735 |
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on May 09, 2025
Flight Schedule Des Moines (Iowa) to Myrtle Beach (South Carolina)
Full flight schedule will help you in detecting at what time planes fly from Des Moines to Myrtle Beach. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
| Departure | Arrival | Flight Details | Flight Duration | Price |
|---|---|---|---|---|
|
06:00 — 17:17
|
06:00 — 09:46
G4444
Allegiant Air
Des Moines — Orlando
6h 1m stop
15:47 — 17:17
NK136
Spirit Airlines
Orlando — Myrtle Beach
|
10h 17m including layover |
Find flight
from$376 |
|
|
07:30 — 17:58
|
07:30 — 11:05
G4431
Allegiant Air
Des Moines — Newark
4h 53m stop
15:58 — 17:58
NK943
Spirit Airlines
Newark — Myrtle Beach
|
9h 28m including layover |
Find flight
from$131 |
|
|
07:30 — 18:13
|
07:30 — 11:05
G4442
Allegiant Air
Des Moines — Newark
5h 4m stop
16:09 — 18:13
NK943
Spirit Airlines
Newark — Myrtle Beach
|
9h 43m including layover |
Find flight
from$201 |
|
|
08:57 — 18:16
|
08:57 — 12:37
G41341
Allegiant Air
Des Moines — Orlando
4h 13m stop
16:50 — 18:16
NK136
Spirit Airlines
Orlando — Myrtle Beach
|
8h 19m including layover |
Find flight
from$357 |
|
|
09:00 — 20:04
|
09:00 — 12:50
G4464
Allegiant Air
Des Moines — Orlando
5h 49m stop
18:39 — 20:04
NK136
Spirit Airlines
Orlando — Myrtle Beach
|
10h 4m including layover |
Find flight
from$216 |
|
|
06:00 — 20:40
|
06:00 — 09:46
G4444
Allegiant Air
Des Moines — Orlando
5h 44m stop
15:30 — 17:45
NK2155
Spirit Airlines
Orlando — Atlantic City
1h 25m stop
19:10 — 20:40
NK1918
Spirit Airlines
Atlantic City — Myrtle Beach
|
13h 40m including layover |
Find flight
from$417 |
|
|
08:00 — 12:56
+1 day
|
08:00 — 09:27
UA1363
United Airlines
Des Moines — Chicago
12h 8m stop
21:35 — 00:43
UA2371
United Airlines
Chicago — Newark
10h 12m stop
10:55 — 12:56
UA3474
United Airlines
Newark — Myrtle Beach
|
27h 56m including layover |
Find flight
from$568 |
|
|
09:02 — 11:56
+1 day
|
09:02 — 10:17
UA581
United Airlines
Des Moines — Denver
13h 42m stop
23:59 — 05:39
UA297
United Airlines
Denver — Newark
4h 21m stop
10:00 — 11:56
UA735
United Airlines
Newark — Myrtle Beach
|
25h 54m including layover |
Find flight
from$655 |
|
|
11:25 — 11:56
+1 day
|
11:25 — 12:53
UA2306
United Airlines
Des Moines — Chicago
57m stop
13:50 — 17:05
UA2329
United Airlines
Chicago — Newark
16h 55m stop
10:00 — 11:56
UA735
United Airlines
Newark — Myrtle Beach
|
23h 31m including layover |
Find flight
from$582 |
|
|
11:25 — 11:56
+1 day
|
11:25 — 12:53
UA2306
United Airlines
Des Moines — Chicago
3h 57m stop
16:50 — 20:13
UA795
United Airlines
Chicago — Newark
13h 47m stop
10:00 — 11:56
UA735
United Airlines
Newark — Myrtle Beach
|
23h 31m including layover |
Find flight
from$582 |
|
|
13:45 — 11:56
+1 day
|
13:45 — 14:51
UA5669
United Airlines
Des Moines — Denver
3h 4m stop
17:55 — 23:35
UA2613
United Airlines
Denver — Newark
10h 25m stop
10:00 — 11:56
UA735
United Airlines
Newark — Myrtle Beach
|
21h 11m including layover |
Find flight
from$582 |
|
|
13:45 — 11:56
+1 day
|
13:45 — 14:51
UA5669
United Airlines
Des Moines — Denver
1h 29m stop
16:20 — 21:57
UA2632
United Airlines
Denver — Newark
12h 3m stop
10:00 — 11:56
UA735
United Airlines
Newark — Myrtle Beach
|
21h 11m including layover |
Find flight
from$582 |
|
|
14:50 — 10:27
+1 day
|
14:50 — 16:13
G42057
Allegiant Air
Des Moines — Las Vegas
6h 14m stop
22:27 — 06:00
NK513
Spirit Airlines
Las Vegas — Miami
2h 45m stop
08:45 — 10:27
NK3647
Spirit Airlines
Miami — Myrtle Beach
|
18h 37m including layover |
Find flight
from$827 |
|
|
14:50 — 15:32
+1 day
|
14:50 — 16:13
G42057
Allegiant Air
Des Moines — Las Vegas
6h 14m stop
22:27 — 06:00
NK513
Spirit Airlines
Las Vegas — Miami
7h 50m stop
13:50 — 15:32
NK948
Spirit Airlines
Miami — Myrtle Beach
|
23h 42m including layover |
Find flight
from$827 |
|
|
15:35 — 10:10
+1 day
|
15:35 — 17:03
G4451
Allegiant Air
Des Moines — Las Vegas
5h 1m stop
22:04 — 06:12
MX527
Mexicana
Las Vegas — Hartford
1h 48m stop
08:00 — 10:10
MX558
Mexicana
Hartford — Myrtle Beach
|
17h 35m including layover |
Find flight
from$256 |
|
|
15:35 — 08:10
+1 day
|
15:35 — 17:03
G4451
Allegiant Air
Des Moines — Las Vegas
4h 56m stop
21:59 — 05:26
NK903
Spirit Airlines
Las Vegas — Orlando
1h 19m stop
06:45 — 08:10
NK292
Spirit Airlines
Orlando — Myrtle Beach
|
15h 35m including layover |
Find flight
from$286 |
|
|
17:10 — 11:56
+1 day
|
17:10 — 18:19
UA1781
United Airlines
Des Moines — Denver
5h 40m stop
23:59 — 05:39
UA297
United Airlines
Denver — Newark
4h 21m stop
10:00 — 11:56
UA735
United Airlines
Newark — Myrtle Beach
|
17h 46m including layover |
Find flight
from$655 |
|
|
18:54 — 12:56
+1 day
|
18:54 — 20:25
UA3433
United Airlines
Des Moines — Chicago
1h 10m stop
21:35 — 00:43
UA2371
United Airlines
Chicago — Newark
10h 12m stop
10:55 — 12:56
UA3474
United Airlines
Newark — Myrtle Beach
|
17h 2m including layover |
Find flight
from$526 |
|
|
18:54 — 12:56
+1 day
|
18:54 — 20:25
UA3433
United Airlines
Des Moines — Chicago
9h 35m stop
06:00 — 09:10
UA1658
United Airlines
Chicago — Newark
1h 45m stop
10:55 — 12:56
UA3474
United Airlines
Newark — Myrtle Beach
|
17h 2m including layover |
Find flight
from$568 |
|
*Departure and arrival times - local. Updated on May 9, 2025
Flight Information
Below we will explain in detail what the flights cost on the destination from Des Moines to Myrtle Beach depends on and how to choose the most interesting flight option for you.
Distance between Des Moines and Myrtle Beach is 1560 miles. Time difference between the cities is 1h. Airplanes depart 06:00 to 18:54 from 1 Des Moines airport and arrive 06:00 to 18:54 to 2 Myrtle Beach airports. Average flight time is 20h 33m.
- The fastest flight 8h 19m
- Average flight time 20h 33m
- The earliest flight 06:00
- The latest flight 18:54
- Distance 970 ml
The cheapest months to travel to Myrtle Beach are november (from 131 $), december (from 201 $), january (from 256 $).
The most expensive months are february (from 376 $), january (from 256 $), december (from 201 $).
What is the lowest airfare Des Moines to Myrtle Beach?
The cheapest plane ticket found by our users is $131. This airfare is for economy class on one-way G4431 flight by Allegiant Air for November 11, 2024 which leaves Des Moines International Airport in Des Moines at 07:30 am and arrives at Myrtle Beach AFB at 17:58.
Economy class
$131
Business class
?
First class
?
Popular Airlines on the Route
The flight Des Moines — Myrtle Beach is served by 2 regular airlines and 1 low-cost airline. Most of the flights on this route are operated by United Airlines - 36 departures per week at the price of from $ 518 . And the most expensive tickets are offered by Allegiant Air airline - from $ 1184.
Direct flights
There’re no direct flights on this route. Try flights with stops.
Connecting Flights
There are 52 flights with layovers on the route. The fastest connecting flight is G41341 by Allegiant Air takes 8h 19m and the cheapest is G4431 by Allegiant Air for $131.
- UA - United Airlinesfrom $518Find
- G4 - Allegiant Airfrom $131Find
See more connecting flights
Airports
You can fly from Des Moines to Myrtle Beach from 1 airports (Des Moines International Airport).
Des Moines airports
- Des Moines International Airport-DSMfrom $131Find
Myrtle Beach airports
- AFB-MYRFind
- Grand Strand Airport-CREFind
Airplanes
There are flights to Myrtle Beach from Des Moines by 2 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top Domestic Destinations from Des Moines
You may also consider searching for discounted plane tickets to some other popular places from Des Moines within United States.
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Top International Destinations from Des Moines
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
- from $77Find
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How to book a plane ticket yourself?
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