Cheap Flights from Tampa, FL to San Diego, CA from $100

Return flight: San Diego – Tampa

On Cheapflightsplus.com you will find 2 direct and 442 connecting flights from Tampa to San Diego. You can compare airfare deals from 7 airlines and multiple travel sites from $100, book and save on cheap plane tickets and last minute offers. Also check out TPA-SAN flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Tampa to San Diego depends on and how to choose the most interesting flight option for you.

Distance between Tampa and San Diego is 3352 miles. Time difference between the cities is 3h. Airplanes depart 05:20 to 22:47 from 4 Tampa airports and arrive 05:20 to 22:47 to 11 San Diego airports. Average flight time is 4h 50m.

  • The fastest flight 4h 50m
  • Average flight time 4h 50m
  • The earliest flight 05:20
  • The latest flight 22:47
  • Distance 2083 ml

The cheapest months to travel to San Diego are may (from 100 $), june (from 108 $), july (from 115 $).

The most expensive months are december (from 269 $), november (from 247 $), february (from 214 $).

What is the lowest airfare Tampa to San Diego?

The cheapest plane ticket found by our users is $100. This airfare is for economy class on one-way F91333 flight by Frontier Airlines for June 5, 2025 which leaves Tampa Int. in Tampa at 19:27 am and arrives at San Diego San Diego at 23:48.

Economy class
$100
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Business class
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First class
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Flight Schedule Tampa (Florida) to San Diego (California)

06:50 — 17:20
13h 30m flight time
Find flight
from$125
06:50 — 09:01 Tampa — Denver
F91113 Frontier Airlines
6h 47m stop
16:50 — 18:25 Denver — San Diego
F94989 Frontier Airlines
07:00 — 23:05
19h 5m flight time
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from$125
06:50 — 09:01 Tampa — Denver
F91113 Frontier Airlines
12h 34m stop
22:29 — 23:59 Denver — San Diego
F92711 Frontier Airlines
07:30 — 11:55
7h 25m flight time
Find flight
from$128
07:30 — 09:29 Tampa — Las Vegas
F91257 Frontier Airlines
1h 19m stop
10:35 — 11:56 Las Vegas — San Diego
F91469 Frontier Airlines
09:00 — 10:50
4h 50m flight time
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from$120
Tampa — San Diego
HA7143 Hawaiian Airlines
09:00 — 10:50
4h 50m flight time
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from$123
Tampa — San Diego
AS433 Alaska Airlines
09:19 — 23:29
17h 10m flight time
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from$108
09:19 — 11:07 Tampa — Las Vegas
NK2579 Spirit Airlines
10h 59m stop
22:42 — 23:56 Las Vegas — San Diego
NK2390 Spirit Airlines
09:19 — 13:17
6h 58m flight time
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from$118
09:19 — 11:07 Tampa — Las Vegas
NK2579 Spirit Airlines
44m stop
16:43 — 18:03 Las Vegas — San Diego
NK2295 Spirit Airlines
09:19 — 19:53
13h 34m flight time
Find flight
from$128
09:19 — 11:07 Tampa — Las Vegas
NK2579 Spirit Airlines
7h 29m stop
18:36 — 19:53 Las Vegas — San Diego
NK2020 Spirit Airlines
15:15 — 23:05
10h 50m flight time
Find flight
from$125
21:30 — 23:43 Tampa — Denver
F93517 Frontier Airlines
4h 12m stop
22:29 — 23:59 Denver — San Diego
F92711 Frontier Airlines
17:04 — 18:03+1day
27h 59m flight time
Find flight
from$129
17:04 — 18:40 Tampa — Atlanta
NK2469 Spirit Airlines
13h 20m stop
08:00 — 09:20 Atlanta — Las Vegas
NK2341 Spirit Airlines
7h 23m stop
16:43 — 18:03 Las Vegas — San Diego
NK2295 Spirit Airlines
19:15 — 00:11+1day
7h 56m flight time
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from$128
19:15 — 21:31 Tampa — Dallas
F91333 Frontier Airlines
1h 17m stop
22:48 — 00:11 Dallas — San Diego
F91769 Frontier Airlines
19:27 — 23:48
7h 21m flight time
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from$100
18:51 — 20:59 Tampa — Dallas
F91333 Frontier Airlines
1h 10m stop
21:59 — 23:25 Dallas — San Diego
F91425 Frontier Airlines
22:03 — 23:02+1day
27h 59m flight time
Find flight
from$114
22:33 — 00:49 Tampa — Denver
F92745 Frontier Airlines
21h 37m stop
22:29 — 23:59 Denver — San Diego
F92711 Frontier Airlines
22:33 — 17:20+1day
21h 47m flight time
Find flight
from$114
22:33 — 00:49 Tampa — Denver
F92745 Frontier Airlines
14h 59m stop
16:50 — 18:25 Denver — San Diego
F94989 Frontier Airlines
22:33 — 09:55+1day
14h 22m flight time
Find flight
from$120
22:33 — 00:49 Tampa — Denver
F92745 Frontier Airlines
7h 33m stop
08:22 — 09:55 Denver — San Diego
F92817 Frontier Airlines
Full flight schedule will help you in detecting at what time planes fly from Tampa to San Diego. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on November 2, 2025.

Popular Airlines on the Route

The flight Tampa — San Diego is served by 7 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 79 departures per week at the price of from $ 123 . And the most expensive tickets are offered by Alaska Airlines airline - from $ 12759.

Direct flights

There are 2 nonstop flights on the route. The fastest direct flight is HA7143 by Hawaiian Airlines takes 4h 50m and the cheapest is F91333 by Frontier Airlines for $120.

  • AS - Alaska Airlines
    from $123
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  • HA - Hawaiian Airlines
    from $120
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See more direct flights

Connecting Flights

There are 442 flights with layovers on the route. The fastest connecting flight is AS6294 by Alaska Airlines takes 6h 43m and the cheapest is F91333 by Frontier Airlines for $100.

  • AS - Alaska Airlines
    from $195
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  • F9 - Frontier Airlines
    from $100
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  • SY - Sun Country Airlines
    from $177
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  • HA - Hawaiian Airlines
    from $156
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  • MX - Mexicana
    from $206
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  • UA - United Airlines
    from $153
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  • NK - Spirit Airlines
    from $108
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See more connecting flights

Airports

You can fly from Tampa to San Diego from 4 airports (Topp Of Tampa, Mac Dill AFB, Peter O'Knight, Tampa Int.).

Tampa airports

  • Topp Of Tampa-KYO
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  • Mac Dill AFB-MCF
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  • Peter O'Knight-TPF
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  • Tampa Int.-TPA
    from $100
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San Diego airports

  • San Diego-SAN
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  • San Diego Regional-USA
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  • Gillespie Field-SEE
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  • Golden Triangle Reg.-GTR
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  • El Cajon-CJN
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  • Lowndes County-UBS
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  • Miramar NAS-NKX
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  • Montgomery Field-MYF
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  • North Island NAS-NZY
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  • Brown Field Municipal-SDM
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  • AFB-CBM
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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