Cheap Flights from Tampa, FL to Charleston, SC from $101

Return flight: Charleston – Tampa

On Cheapflightsplus.com you will find 1 direct and 56 connecting flights from Tampa to Charleston. You can compare airfare deals from 5 airlines and multiple travel sites from $101, book and save on cheap plane tickets and last minute offers. Also check out TPA-CHS flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Tampa to Charleston depends on and how to choose the most interesting flight option for you.

Distance between Tampa and Charleston is 596 miles. Time difference between the cities is 0h. Airplanes depart 05:45 to 21:47 from 4 Tampa airports and arrive 05:45 to 21:47 to 1 Charleston airport. Average flight time is 1h 30m.

  • The fastest flight 1h 30m
  • Average flight time 1h 30m
  • The earliest flight 05:45
  • The latest flight 21:47
  • Distance 371 ml

The cheapest months to travel to Charleston are january (from 101 $).

What is the lowest airfare Tampa to Charleston?

The cheapest plane ticket found by our users is $101. This airfare is for economy class on one-way NK169 flight by Spirit Airlines for January 30, 2026 which leaves Tampa Int. in Tampa at 08:38 am and arrives at Charleston Charleston Intl at 17:36.

Economy class
$101
Find
Business class
?
Find
First class
?
Find

Flight Schedule Tampa (Florida) to Charleston (South Carolina)

07:00 — 22:57
15h 57m flight time
Find flight
from$242
07:00 — 08:58 Tampa — Raleigh
MX134 Mexicana
2h 51m stop
11:49 — 13:21 Raleigh — Ronkonkoma
MX330 Mexicana
7h 24m stop
20:45 — 22:57 Ronkonkoma — Charleston
MX255 Mexicana
07:00 — 23:14
16h 14m flight time
Find flight
from$314
07:00 — 08:58 Tampa — Raleigh
MX134 Mexicana
40m stop
09:38 — 11:22 Raleigh — Syracuse
MX134 Mexicana
9h 33m stop
20:55 — 23:14 Syracuse — Charleston
MX243 Mexicana
08:38 — 17:36
8h 58m flight time
Find flight
from$101
08:38 — 09:45 Tampa — Miami
NK169 Spirit Airlines
6h 7m stop
15:52 — 17:36 Miami — Charleston
NK1055 Spirit Airlines
11:52 — 13:22
1h 30m flight time
Find flight
from$252
Tampa — Charleston
MX100 Mexicana
14:57 — 17:36+1day
26h 39m flight time
Find flight
from$289
14:57 — 16:58 Tampa — Chicago
NK949 Spirit Airlines
12h 17m stop
05:15 — 09:22 Chicago — Miami
NK1986 Spirit Airlines
6h 30m stop
15:52 — 17:36 Miami — Charleston
NK1055 Spirit Airlines
14:57 — 17:36+1day
26h 39m flight time
Find flight
from$309
14:57 — 16:58 Tampa — Chicago
NK949 Spirit Airlines
14h 22m stop
07:20 — 11:35 Chicago — Miami
NK570 Spirit Airlines
4h 17m stop
15:52 — 17:36 Miami — Charleston
NK1055 Spirit Airlines
15:50 — 22:57
7h 7m flight time
Find flight
from$300
15:50 — 18:38 Tampa — Ronkonkoma
F93324 Frontier Airlines
2h 7m stop
20:45 — 22:57 Ronkonkoma — Charleston
MX255 Mexicana
17:56 — 17:36+1day
23h 40m flight time
Find flight
from$277
17:56 — 18:47 Tampa — New Orleans
NK2853 Spirit Airlines
11h 18m stop
06:05 — 08:55 New Orleans — Miami
NK240 Spirit Airlines
6h 57m stop
15:52 — 17:36 Miami — Charleston
NK1055 Spirit Airlines
18:55 — 17:36+1day
22h 41m flight time
Find flight
from$169
18:55 — 20:05 Tampa — Miami
NK758 Spirit Airlines
19h 47m stop
15:52 — 17:36 Miami — Charleston
NK1055 Spirit Airlines
19:11 — 17:36+1day
22h 25m flight time
Find flight
from$280
19:11 — 21:38 Tampa — Atlantic City
NK2849 Spirit Airlines
8h 22m stop
06:00 — 08:52 Atlantic City — Miami
NK200 Spirit Airlines
7h stop
15:52 — 17:36 Miami — Charleston
NK1055 Spirit Airlines
21:42 — 08:38+2days
34h 56m flight time
Find flight
from$306
21:42 — 00:18 Tampa — Philadelphia
F91474 Frontier Airlines
20h 25m stop
20:43 — 23:28 Philadelphia — Orlando
NK388 Spirit Airlines
7h 42m stop
07:10 — 08:38 Orlando — Charleston
MX842 Mexicana
21:42 — 08:38+2days
34h 56m flight time
Find flight
from$307
21:42 — 00:18 Tampa — Philadelphia
F91474 Frontier Airlines
15h 36m stop
15:54 — 18:44 Philadelphia — Orlando
F94173 Frontier Airlines
12h 26m stop
07:10 — 08:38 Orlando — Charleston
MX842 Mexicana
21:47 — 17:36+1day
19h 49m flight time
Find flight
from$169
21:47 — 22:56 Tampa — Miami
NK1311 Spirit Airlines
16h 56m stop
15:52 — 17:36 Miami — Charleston
NK1055 Spirit Airlines
21:47 — 08:38+2days
34h 51m flight time
Find flight
from$318
21:47 — 22:56 Tampa — Miami
NK1311 Spirit Airlines
7h 43m stop
06:39 — 07:43 Miami — Orlando
NK550 Spirit Airlines
23h 27m stop
07:10 — 08:38 Orlando — Charleston
MX842 Mexicana
21:47 — 21:30+1day
23h 43m flight time
Find flight
from$339
21:47 — 22:56 Tampa — Miami
NK1311 Spirit Airlines
11h 20m stop
10:16 — 12:16 Miami — Cancun
NK527 Spirit Airlines
6h 39m stop
18:55 — 21:30 Cancun — Charleston
MX397 Mexicana
Full flight schedule will help you in detecting at what time planes fly from Tampa to Charleston. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on February 6, 2026.

Popular Airlines on the Route

The flight Tampa — Charleston is served by 5 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Mexicana - 5 departures per week at the price of from $ 242 . And the most expensive tickets are offered by United Airlines airline - from $ 1038.

Direct flights

There are 1 nonstop flights on the route. The fastest direct flight is MX100 by Mexicana takes 1h 30m and the cheapest is NK169 by Spirit Airlines for $252.

  • MX - Mexicana
    from $252
    Find
See more direct flights

Connecting Flights

There are 56 flights with layovers on the route. The fastest connecting flight is UA326 by United Airlines takes 5h 14m and the cheapest is NK169 by Spirit Airlines for $101.

  • F9 - Frontier Airlines
    from $300
    Find
  • PD - Porter Airlines
    from $972
    Find
  • MX - Mexicana
    from $242
    Find
  • UA - United Airlines
    from $397
    Find
  • NK - Spirit Airlines
    from $101
    Find
See more connecting flights

Airports

You can fly from Tampa to Charleston from 4 airports (Topp Of Tampa, Mac Dill AFB, Peter O'Knight, Tampa Int.).

Tampa airports

  • Topp Of Tampa-KYO
    Find
  • Mac Dill AFB-MCF
    Find
  • Peter O'Knight-TPF
    Find
  • Tampa Int.-TPA
    from $101
    Find

Charleston airports

  • Charleston Intl-CHS
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back