Cheap Flights from Syracuse, NY to Chicago, IL from $181

Return flight: Chicago – Syracuse
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On Cheapflightsplus.com you will find 11 direct and 398 connecting flights from Syracuse to Chicago. You can compare airfare deals from 5 airlines and multiple travel sites from $181, book and save on cheap plane tickets and last minute offers. Also check out SYR-CHI flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Syracuse to Chicago Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $181 (one-way), $310 (round-trip).
Direct flights
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Best Flights from Syracuse to Chicago Today

Take a look at the list of non stop flights and flights with layovers from Syracuse to Chicago with the lowest price of $181. The fastest direct flight takes 2h 12m and the fastest connecting – 4h 24m.
Price Departure Arrival Flight Duration Airline Flight
from $262
Find flight
17:43
Syracuse
Syracuse Hancock
 18:55
Chicago
O'Hare International
 2h 12m United Airlines
UA533
from $342
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17:40
Syracuse
Syracuse Hancock
 18:55
Chicago
O'Hare International
 2h 15m United Airlines
UA5701
from $451
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17:34
Syracuse
Syracuse Hancock
 18:52
Chicago
O'Hare International
 2h 18m United Airlines
UA4500
from $97
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10:50
Syracuse
Syracuse Hancock
 16:40
Chicago
O'Hare International
 6h 50m
layover
2h 30m - Raleigh
 Frontier Airlines
F94207
F93351
from $101
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20:32
Syracuse
Syracuse Hancock
 15:33+1 день
Chicago
O'Hare International
 20h 1m
layover
15h 46m - Nashville
 Allegiant Air
G4326
NK2028
from $128
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20:32
Syracuse
Syracuse Hancock
 18:44+1 день
Chicago
O'Hare International
 23h 12m
layover
9h 26m - Nashville
6h 31m - Orlando
 Allegiant Air
G4326
NK2251
NK2190
from $150
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15:02
Syracuse
Syracuse Hancock
 18:44+1 день
Chicago
O'Hare International
 28h 42m
layover
13h 13m - Myrtle Beach
9h 6m - Orlando
 Allegiant Air
G4349
NK2644
NK2190
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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 10, 2025
Full flight schedule will help you in detecting at what time planes fly from Syracuse to Chicago. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
06:25 — 07:45
06:25 — 07:45 UA1778 United Airlines
Syracuse — Chicago
2h 20m
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from$262
10:45 — 12:05
10:45 — 12:05 UA4510 United Airlines
Syracuse — Chicago
2h 20m
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from$262
10:50 — 16:40
10:06 — 11:51 F94207 Frontier Airlines
Syracuse — Raleigh
2h 30m stop
15:38 — 17:10 F93351 Frontier Airlines
Raleigh — Chicago
6h 50m
including layover
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from$97
10:52 — 12:13
10:52 — 12:13 UA3569 United Airlines
Syracuse — Chicago
2h 21m
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from$264
12:50 — 14:10
12:50 — 14:10 UA4472 United Airlines
Syracuse — Chicago
2h 20m
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from$262
16:09 — 00:17
+1 day
16:09 — 18:35 F93117 Frontier Airlines
Syracuse — Atlanta
4h 23m stop
22:58 — 00:17 F93397 Frontier Airlines
Atlanta — Chicago
9h 8m
including layover
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from$103
17:34 — 18:55
17:34 — 18:55 UA5572 United Airlines
Syracuse — Chicago
2h 21m
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from$262
17:34 — 18:55
17:34 — 18:55 UA3707 United Airlines
Syracuse — Chicago
2h 21m
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from$292
17:40 — 18:55
17:40 — 18:55 UA481 United Airlines
Syracuse — Chicago
2h 15m
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from$262
17:40 — 18:55
17:40 — 18:55 UA1708 United Airlines
Syracuse — Chicago
2h 15m
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from$264
17:43 — 18:55
17:43 — 18:55 UA533 United Airlines
Syracuse — Chicago
2h 12m
Find flight
from$262
20:32 — 15:33
+1 day
20:36 — 21:51 G4326 Allegiant Air
Syracuse — Nashville
15h 46m stop
14:28 — 16:25 NK2028 Spirit Airlines
Nashville — Chicago
20h 1m
including layover
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from$101
20:36 — 16:25
+1 day
20:36 — 21:43 G41975 Allegiant Air
Syracuse — Nashville
16h 45m stop
14:28 — 16:25 NK2028 Spirit Airlines
Nashville — Chicago
20h 49m
including layover
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from$101
21:49 — 19:25
+1 day
21:43 — 00:44 F92289 Frontier Airlines
Syracuse — Orlando
16h 46m stop
18:20 — 20:17 F93853 Frontier Airlines
Orlando — Chicago
22h 36m
including layover
Find flight
from$102
21:49 — 00:06
+2 days
21:43 — 00:44 F92289 Frontier Airlines
Syracuse — Orlando
21h 13m stop
21:57 — 00:04 F92791 Frontier Airlines
Orlando — Chicago
27h 17m
including layover
Find flight
from$102
*Departure and arrival times - local. Updated on September 10, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Syracuse to Chicago depends on and how to choose the most interesting flight option for you.

Distance between Syracuse and Chicago is 954 miles. Time difference between the cities is 1h. Airplanes depart 06:00 to 21:49 from 1 Syracuse airport and arrive 06:00 to 21:49 to 7 Chicago airports. Average flight time is 2h 20m.

  • The fastest flight 2h 12m
  • Average flight time 2h 20m
  • The earliest flight 06:00
  • The latest flight 21:49
  • Distance 593 ml

Popular Airlines on the Route

The flight Syracuse — Chicago is served by 5 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Frontier Airlines - 6 departures per week at the price of from $ 97 . And the most expensive tickets are offered by United Airlines airline - from $ 748.

Direct flights

There are 11 nonstop flights on the route. The fastest direct flight is UA533 by United Airlines takes 2h 12m.

  • UA - United Airlines
    from $262
    Find
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Connecting Flights

There are 398 flights with layovers on the route. The fastest connecting flight is UA4496 by United Airlines takes 4h 24m.

  • F9 - Frontier Airlines
    from $97
    Find
  • SY - Sun Country Airlines
    from $130
    Find
  • MX - Mexicana
    from $251
    Find
  • UA - United Airlines
    from $222
    Find
  • G4 - Allegiant Air
    from $101
    Find
See more connecting flights

Airports

You can fly from Syracuse to Chicago from 1 airports (Syracuse Hancock).

Syracuse airports

  • Syracuse Hancock-SYR
    from $97
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Chicago airports

  • O'Hare International-ORD
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  • Midway-MDW
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  • Dupage County-DPA
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  • Chicago FSS-CHI
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  • Merrill C Meigs (closed)-CGX
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  • Pal-Waukee-PWK
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  • Chicago NAS-NOH
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Airplanes

There are flights to Chicago from Syracuse by 5 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Syracuse

You may also consider searching for discounted plane tickets to some other popular places from Syracuse within United States.

Top International Destinations from Syracuse

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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