Cheap Flights from Rome to San Francisco, CA from $307
On Cheapflightsplus.com you will find 3 direct and 998 connecting flights from Rome to San Francisco. You can compare airfare deals from 38 airlines and multiple travel sites from $307, book and save on cheap plane tickets and last minute offers. Also check out ROM-SFO flight schedule to find best flight time, convenient departure and arrival airports.
Flight Information
Below we will explain in detail what the flights cost on the destination from Rome to San Francisco depends on and how to choose the most interesting flight option for you.
Distance between Rome and San Francisco is 10061 miles. Time difference between the cities is 9h. Airplanes depart 05:45 to 23:55 from 4 Rome airports and arrive 05:45 to 23:55 to 3 San Francisco airports. Average flight time is 12h 35m.
- The fastest flight 12h 35m
- Average flight time 12h 35m
- The earliest flight 05:45
- The latest flight 23:55
- Distance 6252 ml
Best Flights from Rome to San Francisco Today
Price | Departure | Arrival | Flight Duration | Airline | Flight |
---|---|---|---|---|---|
from $730 | 09:10 Rome Fiumicino | 13:15 San Francisco San Francisco | 13h 5m | Alitalia | AZ640 |
from $888 | 15:40 Rome Fiumicino | 19:15 San Francisco San Francisco | 12h 35m | United Airlines | UA506 |
from $1650 | 15:40 Rome Fiumicino | 19:15 San Francisco San Francisco | 12h 35m | Lufthansa | LH9360 |
from $307 | 09:00 Rome Fiumicino | 17:25 San Francisco San Francisco | 17h 25m layover 2h 20m - Barcelona | Vueling | VY6101 VY9791 |
from $347 | 07:15 Rome Fiumicino | 16:08 San Francisco San Francisco | 17h 53m layover 3h 49m - Los Angeles | N0 | N0411 HA6207 |
from $370 | 06:40 Rome Fiumicino | 23:59 San Francisco San Francisco | 26h 19m layover 7h 45m - Paris 3h 29m - Los Angeles | Aero Services Executive | W46061 N0311 HA6206 |
from $397 | 19:05 Rome Fiumicino | 14:55+1 день San Francisco San Francisco | 28h 50m layover 8h 50m - New York 2h 11m - Seattle | N0 | N0401 HA4991 HA6901 |
The cheapest months to travel to San Francisco are august (from 307 $), october (from 379 $), september (from 418 $).
The most expensive months are january (from 609 $), february (from 607 $), november (from 607 $).
What is the lowest airfare Rome to San Francisco?
The cheapest plane ticket found by our users is $307. This airfare is for economy class on one-way VY6109 flight by Vueling for August 7, 2025 which leaves Fiumicino in Rome at 06:25 am and arrives at San Francisco San Francisco at 17:25.
Flight Schedule Rome to San Francisco (California)
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Popular Airlines on the Route
The flight Rome — San Francisco is served by 38 regular airlines and 10 low-cost airlines. Most of the flights on this route are operated by Condor Airlines - 2 departures per week at the price of from $ 618 . And the most expensive tickets are offered by Lufthansa airline - from $ 1650.
Direct flights
There are 3 nonstop flights on the route. The fastest direct flight is UA506 by United Airlines takes 12h 35m and the cheapest is VY6109 by Vueling for $730.
- AZ - Alitaliafrom $730Find
- UA - United Airlinesfrom $888Find
- LH - Lufthansafrom $1650Find
Connecting Flights
There are 998 flights with layovers on the route. The fastest connecting flight is KL1600 by KLM takes 14h 15m and the cheapest is VY6109 by Vueling for $307.
- DE - Condor Airlinesfrom $618Find
- XZ - Ivoire Aero-Servicesfrom $523Find
- VY - Vuelingfrom $307Find
- FI - Icelandairfrom $528Find
- JU - Air Serbiafrom $591Find
- FR - Ryanairfrom $419Find
- LX - SWISS International Air Linesfrom $1042Find
- LY - EL ALfrom $1019Find
- A3 - Aegean Airlinesfrom $541Find
- DY - Norwegianfrom $742Find
- IB - Iberiafrom $501Find
- SN - Brussels Airlinesfrom $657Find
Airports
You can fly from Rome to San Francisco from 4 airports (Termini Rail Stn., Mestre Rail Stn., Ciampino, Fiumicino).
Rome airports
- Termini Rail Stn.-XRJFind
- Mestre Rail Stn.-XVYFind
- Ciampino-CIAfrom $646Find
- Fiumicino-FCOfrom $307Find
San Francisco airports
- San Francisco-SFOFind
- Embarkadero-EMBFind
- China Basin Heliport-JCCFind
Airplanes
There are flights to San Francisco from Rome by 38 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.
Top International Destinations from Rome
Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.
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How to book a plane ticket yourself?

- Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
- Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
- Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
- Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
- That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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