Cheap Flights from Rome to San Diego, CA from $422

Return flight: San Diego – Rome

On Cheapflightsplus.com you will find 1000 connecting flights from Rome to San Diego. You can compare airfare deals from 37 airlines and multiple travel sites from $422, book and save on cheap plane tickets and last minute offers. Also check out ROM-SAN flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Rome to San Diego depends on and how to choose the most interesting flight option for you.

Distance between Rome and San Diego is 10255 miles. Time difference between the cities is 9h. Airplanes depart 05:55 to 23:55 from 4 Rome airports and arrive 05:55 to 23:55 to 11 San Diego airports. Average flight time is 30h 37m.

  • The fastest flight 15h 20m
  • Average flight time 30h 37m
  • The earliest flight 05:55
  • The latest flight 23:55
  • Distance 6373 ml

The cheapest months to travel to San Diego are october (from 422 $), december (from 422 $), august (from 423 $).

The most expensive months are january (from 1 250 $), february (from 1 233 $), november (from 627 $).

What is the lowest airfare Rome to San Diego?

The cheapest plane ticket found by our users is $422. This airfare is for economy class on one-way N0401 flight by N0 for October 30, 2025 which leaves Fiumicino in Rome at 19:05 am and arrives at San Diego San Diego at 18:19.

Economy class
$422
Find
Business class
?
Find
First class
?
Find

Flight Schedule Rome to San Diego (California)

06:55 — 14:50
16h 55m flight time
Find flight
from$525
06:55 — 08:40 Rome — London
BA567 British Airways
2h 50m stop
11:30 — 14:50 London — San Diego
BA265 British Airways
07:20 — 14:50
16h 30m flight time
Find flight
from$525
07:15 — 09:00 Rome — London
BA551 British Airways
2h 25m stop
11:30 — 14:50 London — San Diego
BA265 British Airways
10:00 — 17:36
16h 36m flight time
Find flight
from$524
10:00 — 15:00 Rome — Dallas
BA1628 British Airways
1h 30m stop
16:58 — 17:56 Dallas — San Diego
BA2473 British Airways
10:00 — 19:53
18h 53m flight time
Find flight
from$524
10:00 — 15:00 Rome — Dallas
BA1628 British Airways
3h 45m stop
19:01 — 20:04 Dallas — San Diego
BA2474 British Airways
10:00 — 21:36
20h 36m flight time
Find flight
from$524
10:00 — 15:00 Rome — Dallas
BA1628 British Airways
5h 43m stop
20:45 — 21:45 Dallas — San Diego
BA1799 British Airways
10:00 — 22:30
21h 30m flight time
Find flight
from$524
10:00 — 15:00 Rome — Dallas
BA1628 British Airways
6h 30m stop
23:15 — 00:09 Dallas — San Diego
BA2476 British Airways
10:00 — 00:11+1day
23h 11m flight time
Find flight
from$524
10:00 — 15:00 Rome — Dallas
BA1628 British Airways
8h 19m stop
23:19 — 00:11 Dallas — San Diego
BA5297 British Airways
11:05 — 19:10
17h 5m flight time
Find flight
from$524
11:05 — 14:30 Rome — Chicago
BA1569 British Airways
2h 24m stop
17:00 — 19:16 Chicago — San Diego
BA5305 British Airways
11:05 — 23:23
21h 18m flight time
Find flight
from$524
11:05 — 14:30 Rome — Chicago
BA1569 British Airways
6h 30m stop
21:00 — 23:27 Chicago — San Diego
BA5306 British Airways
13:10 — 21:12
17h 2m flight time
Find flight
from$524
13:10 — 16:55 Rome — Philadelphia
BA1576 British Airways
1h 55m stop
19:25 — 22:27 Philadelphia — San Diego
BA6585 British Airways
13:10 — 21:23
17h 13m flight time
Find flight
from$527
13:10 — 16:40 Rome — Philadelphia
BA1576 British Airways
1h 45m stop
16:00 — 18:32 Philadelphia — San Diego
BA5436 British Airways
19:05 — 12:49+1day
26h 44m flight time
Find flight
from$423
19:05 — 22:30 Rome — New York
N0401 N0
11h 30m stop
10:00 — 12:52 New York — San Diego
HA4989 Hawaiian Airlines
19:05 — 19:24+1day
33h 19m flight time
Find flight
from$423
19:05 — 22:30 Rome — New York
N0401 N0
17h 58m stop
16:28 — 19:24 New York — San Diego
HA4923 Hawaiian Airlines
21:00 — 14:50+1day
26h 50m flight time
Find flight
from$526
20:30 — 22:05 Rome — London
BA555 British Airways
12h 55m stop
11:30 — 14:50 London — San Diego
BA265 British Airways
21:05 — 14:50+1day
26h 45m flight time
Find flight
from$525
15:30 — 17:10 Rome — London
BA547 British Airways
12h 45m stop
11:30 — 14:50 London — San Diego
BA265 British Airways
Full flight schedule will help you in detecting at what time planes fly from Rome to San Diego. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on October 27, 2025.

Popular Airlines on the Route

The flight Rome — San Diego is served by 37 regular airlines and 8 low-cost airlines. Most of the flights on this route are operated by Condor Airlines - 8 departures per week at the price of from $ 870 . And the most expensive tickets are offered by Air Canada airline - from $ 1726.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 1000 flights with layovers on the route. The fastest connecting flight is BA553 by British Airways takes 15h 20m and the cheapest is N0401 by N0 for $422.

  • DE - Condor Airlines
    from $870
    Find
  • XZ - Ivoire Aero-Services
    from $577
    Find
  • VY - Vueling
    from $427
    Find
  • FI - Icelandair
    from $528
    Find
  • LO - LOT
    from $1512
    Find
  • LS - Jet2.com
    from $1089
    Find
  • JU - Air Serbia
    from $979
    Find
  • FR - Ryanair
    from $505
    Find
  • LX - SWISS International Air Lines
    from $903
    Find
  • LY - EL AL
    from $1108
    Find
  • A3 - Aegean Airlines
    from $581
    Find
  • IB - Iberia
    from $522
    Find
See more connecting flights

Airports

You can fly from Rome to San Diego from 4 airports (Termini Rail Stn., Mestre Rail Stn., Ciampino, Fiumicino).

Rome airports

  • Termini Rail Stn.-XRJ
    Find
  • Mestre Rail Stn.-XVY
    Find
  • Ciampino-CIA
    from $505
    Find
  • Fiumicino-FCO
    from $422
    Find

San Diego airports

  • San Diego-SAN
    Find
  • San Diego Regional-USA
    Find
  • Gillespie Field-SEE
    Find
  • Golden Triangle Reg.-GTR
    Find
  • El Cajon-CJN
    Find
  • Lowndes County-UBS
    Find
  • Miramar NAS-NKX
    Find
  • Montgomery Field-MYF
    Find
  • North Island NAS-NZY
    Find
  • Brown Field Municipal-SDM
    Find
  • AFB-CBM
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back