Cheap Flights from Rome to San Diego, CA from $420

Return flight: San Diego – Rome

On Cheapflightsplus.com you will find 1000 connecting flights from Rome to San Diego. You can compare airfare deals from 37 airlines and multiple travel sites from $420, book and save on cheap plane tickets and last minute offers. Also check out ROM-SAN flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Rome to San Diego Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $420 (one-way), $720 (round-trip).
Direct flights
  • Check to choose departure date Check to choose departure date
Check prices for return flight
Find flights
Full flight schedule will help you in detecting at what time planes fly from Rome to San Diego. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
06:55 — 14:50
06:55 — 08:40 BA567 British Airways
Rome — London
2h 50m stop
11:30 — 14:50 BA265 British Airways
London — San Diego
16h 55m
including layover
Find flight
from$523
07:20 — 14:50
07:15 — 09:00 BA551 British Airways
Rome — London
2h 25m stop
11:30 — 14:50 BA265 British Airways
London — San Diego
16h 30m
including layover
Find flight
from$523
10:00 — 21:36
10:00 — 15:00 BA1628 British Airways
Rome — Dallas
5h 43m stop
20:45 — 21:45 BA1799 British Airways
Dallas — San Diego
20h 36m
including layover
Find flight
from$521
10:00 — 22:30
10:00 — 15:00 BA1628 British Airways
Rome — Dallas
6h 30m stop
23:15 — 00:09 BA2476 British Airways
Dallas — San Diego
21h 30m
including layover
Find flight
from$521
10:00 — 00:11
+1 day
10:00 — 15:00 BA1628 British Airways
Rome — Dallas
8h 19m stop
23:19 — 00:11 BA5297 British Airways
Dallas — San Diego
23h 11m
including layover
Find flight
from$521
11:05 — 19:10
11:05 — 14:30 BA1569 British Airways
Rome — Chicago
2h 24m stop
17:00 — 19:16 BA5305 British Airways
Chicago — San Diego
17h 5m
including layover
Find flight
from$521
11:05 — 23:23
11:05 — 14:30 BA1569 British Airways
Rome — Chicago
6h 30m stop
21:00 — 23:27 BA5306 British Airways
Chicago — San Diego
21h 18m
including layover
Find flight
from$521
12:45 — 14:50
+1 day
12:40 — 14:30 BA549 British Airways
Rome — London
20h 55m stop
11:30 — 14:50 BA265 British Airways
London — San Diego
35h 5m
including layover
Find flight
from$536
13:10 — 21:12
13:10 — 16:55 BA1576 British Airways
Rome — Philadelphia
1h 55m stop
19:25 — 22:27 BA6585 British Airways
Philadelphia — San Diego
17h 2m
including layover
Find flight
from$521
13:55 — 14:50
+1 day
13:55 — 15:35 BA517 British Airways
Rome — London
19h 55m stop
11:30 — 14:50 BA265 British Airways
London — San Diego
33h 55m
including layover
Find flight
from$536
19:05 — 19:24
+1 day
19:05 — 22:30 N0401 N0
Rome — New York
17h 58m stop
16:28 — 19:24 HA4923 Hawaiian Airlines
New York — San Diego
33h 19m
including layover
Find flight
from$420
19:05 — 12:49
+1 day
19:05 — 22:30 N0401 N0
Rome — New York
11h 30m stop
10:00 — 12:52 HA4989 Hawaiian Airlines
New York — San Diego
26h 44m
including layover
Find flight
from$523
19:05 — 12:49
+1 day
18:40 — 22:00 N0401 N0
Rome — New York
11h 30m stop
09:30 — 12:30 AS35 Alaska Airlines
New York — San Diego
26h 44m
including layover
Find flight
from$527
21:00 — 14:50
+1 day
20:30 — 22:05 BA555 British Airways
Rome — London
12h 55m stop
11:30 — 14:50 BA265 British Airways
London — San Diego
26h 50m
including layover
Find flight
from$523
21:05 — 14:50
+1 day
15:30 — 17:10 BA547 British Airways
Rome — London
12h 45m stop
11:30 — 14:50 BA265 British Airways
London — San Diego
26h 45m
including layover
Find flight
from$523
*Departure and arrival times - local. Updated on September 16, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Rome to San Diego depends on and how to choose the most interesting flight option for you.

Distance between Rome and San Diego is 10255 miles. Time difference between the cities is 9h. Airplanes depart 05:55 to 23:55 from 4 Rome airports and arrive 05:55 to 23:55 to 11 San Diego airports. Average flight time is 30h 37m.

  • The fastest flight 15h 20m
  • Average flight time 30h 37m
  • The earliest flight 05:55
  • The latest flight 23:55
  • Distance 6373 ml

The cheapest months to travel to San Diego are december (from 420 $), september (from 420 $), august (from 420 $).

The most expensive months are january (from 1 243 $), february (from 1 226 $), november (from 623 $).

What is the lowest airfare Rome to San Diego?

The cheapest plane ticket found by our users is $420. This airfare is for economy class on one-way N0401 flight by N0 for August 27, 2025 which leaves Fiumicino in Rome at 19:05 am and arrives at San Diego San Diego at 19:24.

Economy class
$420
Find
Business class
?
Find
First class
?
Find

Popular Airlines on the Route

The flight Rome — San Diego is served by 37 regular airlines and 8 low-cost airlines. Most of the flights on this route are operated by Condor Airlines - 8 departures per week at the price of from $ 865 . And the most expensive tickets are offered by Iberia airline - from $ 1978.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 1000 flights with layovers on the route. The fastest connecting flight is BA553 by British Airways takes 15h 20m and the cheapest is N0401 by N0 for $420.

  • DE - Condor Airlines
    from $865
    Find
  • XZ - Ivoire Aero-Services
    from $574
    Find
  • VY - Vueling
    from $424
    Find
  • FI - Icelandair
    from $525
    Find
  • LO - LOT
    from $1504
    Find
  • LS - Jet2.com
    from $1083
    Find
  • JU - Air Serbia
    from $973
    Find
  • FR - Ryanair
    from $502
    Find
  • LX - SWISS International Air Lines
    from $898
    Find
  • LY - EL AL
    from $1102
    Find
  • A3 - Aegean Airlines
    from $578
    Find
  • IB - Iberia
    from $519
    Find
See more connecting flights

Airports

You can fly from Rome to San Diego from 4 airports (Termini Rail Stn., Mestre Rail Stn., Ciampino, Fiumicino).

Rome airports

  • Termini Rail Stn.-XRJ
    Find
  • Mestre Rail Stn.-XVY
    Find
  • Ciampino-CIA
    from $502
    Find
  • Fiumicino-FCO
    from $420
    Find

San Diego airports

  • San Diego-SAN
    Find
  • San Diego Regional-USA
    Find
  • Gillespie Field-SEE
    Find
  • Golden Triangle Reg.-GTR
    Find
  • El Cajon-CJN
    Find
  • Lowndes County-UBS
    Find
  • Miramar NAS-NKX
    Find
  • Montgomery Field-MYF
    Find
  • North Island NAS-NZY
    Find
  • Brown Field Municipal-SDM
    Find
  • AFB-CBM
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back