Cheap Flights from Portland, ME to San Diego, CA from $188

Return flight: San Diego – Portland

On Cheapflightsplus.com you will find 305 connecting flights from Portland to San Diego. You can compare airfare deals from 4 airlines and multiple travel sites from $188, book and save on cheap plane tickets and last minute offers. Also check out PWM-SAN flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Portland to San Diego depends on and how to choose the most interesting flight option for you.

Distance between Portland and San Diego is 4212 miles. Time difference between the cities is 3h. Airplanes depart 05:08 to 20:52 from 1 Portland airport and arrive 05:08 to 20:52 to 11 San Diego airports. Average flight time is 16h 48m.

  • The fastest flight 7h 47m
  • Average flight time 16h 48m
  • The earliest flight 05:08
  • The latest flight 20:52
  • Distance 2618 ml

The cheapest months to travel to San Diego are june (from 188 $), july (from 194 $), may (from 224 $).

The most expensive months are september (from 253 $), october (from 237 $), august (from 236 $).

What is the lowest airfare Portland to San Diego?

The cheapest plane ticket found by our users is $188. This airfare is for economy class on one-way SY1822 flight by Sun Country Airlines for July 5, 2025 which leaves Portland Intl Jetport in Portland at 12:58 am and arrives at San Diego San Diego at 23:29.

Economy class
$188
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Business class
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First class
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Flight Schedule Portland (Maine) to San Diego (California)

05:40 — 11:16
8h 36m flight time
Find flight
from$241
05:40 — 07:30 Portland — Washington D.C.
UA3622 United Airlines
1h 26m stop
08:56 — 11:16 Washington D.C. — San Diego
UA1930 United Airlines
05:45 — 11:22
8h 37m flight time
Find flight
from$237
05:45 — 07:33 Portland — Washington D.C.
UA3415 United Airlines
1h 27m stop
09:00 — 11:22 Washington D.C. — San Diego
UA1930 United Airlines
06:00 — 11:40
8h 40m flight time
Find flight
from$237
06:00 — 07:51 Portland — Chicago
UA1857 United Airlines
1h 22m stop
09:13 — 11:40 Chicago — San Diego
UA660 United Airlines
06:14 — 11:40
8h 26m flight time
Find flight
from$240
06:14 — 08:05 Portland — Chicago
UA1030 United Airlines
1h 8m stop
09:13 — 11:40 Chicago — San Diego
UA660 United Airlines
10:05 — 15:03
7h 58m flight time
Find flight
from$240
10:05 — 11:53 Portland — Washington D.C.
UA3438 United Airlines
47m stop
12:40 — 15:03 Washington D.C. — San Diego
UA2029 United Airlines
12:11 — 19:09
9h 58m flight time
Find flight
from$240
12:10 — 13:59 Portland — Newark
UA3719 United Airlines
2h 25m stop
16:25 — 19:09 Newark — San Diego
UA1626 United Airlines
12:32 — 17:19
7h 47m flight time
Find flight
from$213
12:58 — 15:06 Portland — Minneapolis
SY1822 Sun Country Airlines
56m stop
14:48 — 16:31 Minneapolis — San Diego
SY407 Sun Country Airlines
12:32 — 11:01+1day
25h 29m flight time
Find flight
from$236
12:32 — 14:40 Portland — Minneapolis
SY1822 Sun Country Airlines
18h 38m stop
09:18 — 11:01 Minneapolis — San Diego
SY1639 Sun Country Airlines
14:22 — 20:19
8h 57m flight time
Find flight
from$237
14:14 — 16:12 Portland — Washington D.C.
UA3624 United Airlines
1h 35m stop
17:50 — 20:19 Washington D.C. — San Diego
UA2054 United Airlines
15:13 — 21:23
9h 10m flight time
Find flight
from$237
15:13 — 17:02 Portland — Newark
UA3620 United Airlines
1h 28m stop
18:30 — 21:23 Newark — San Diego
UA2624 United Airlines
15:35 — 20:25
7h 50m flight time
Find flight
from$237
15:35 — 18:00 Portland — Denver
UA1092 United Airlines
1h stop
19:00 — 20:25 Denver — San Diego
UA540 United Airlines
15:35 — 22:14
9h 39m flight time
Find flight
from$237
15:35 — 18:00 Portland — Denver
UA1092 United Airlines
2h 50m stop
20:50 — 22:14 Denver — San Diego
UA1835 United Airlines
15:35 — 20:25
7h 50m flight time
Find flight
from$240
15:35 — 18:00 Portland — Denver
UA2852 United Airlines
1h stop
19:00 — 20:25 Denver — San Diego
UA540 United Airlines
15:35 — 22:14
9h 39m flight time
Find flight
from$240
15:35 — 18:00 Portland — Denver
UA2852 United Airlines
2h 50m stop
20:50 — 22:14 Denver — San Diego
UA1835 United Airlines
16:56 — 22:02
8h 6m flight time
Find flight
from$240
16:56 — 18:47 Portland — Chicago
UA2466 United Airlines
48m stop
19:35 — 22:02 Chicago — San Diego
UA734 United Airlines
Full flight schedule will help you in detecting at what time planes fly from Portland to San Diego. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on November 3, 2025.

Popular Airlines on the Route

The flight Portland — San Diego is served by 4 regular airlines and 1 low-cost airline. Most of the flights on this route are operated by Alaska Airlines - 4 departures per week at the price of from $ 280 . And the most expensive tickets are offered by United Airlines airline - from $ 929.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 305 flights with layovers on the route. The fastest connecting flight is SY1822 by Sun Country Airlines takes 7h 47m and the cheapest is SY1822 by Sun Country Airlines for $188.

  • AS - Alaska Airlines
    from $280
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  • SY - Sun Country Airlines
    from $188
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  • MX - Mexicana
    from $304
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  • UA - United Airlines
    from $237
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See more connecting flights

Airports

You can fly from Portland to San Diego from 1 airports (Portland Intl Jetport).

Portland airports

  • Portland Intl Jetport-PWM
    from $188
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San Diego airports

  • San Diego-SAN
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  • San Diego Regional-USA
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  • Gillespie Field-SEE
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  • Golden Triangle Reg.-GTR
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  • El Cajon-CJN
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  • Lowndes County-UBS
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  • Miramar NAS-NKX
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  • Montgomery Field-MYF
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  • North Island NAS-NZY
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  • Brown Field Municipal-SDM
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  • AFB-CBM
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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