Cheap Flights from Panama City to Louisville, KY from $288

On Cheapflightsplus.com you will find 14 connecting flights from Panama City to Louisville. You can compare airfare deals from 2 airlines and multiple travel sites from $288, book and save on cheap plane tickets and last minute offers. Also check out PTY-SDF flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Panama City to Louisville Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $288 (one-way), $494 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Panama City to Louisville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
03:19 — 17:57
03:19 — 04:54 AV41 Avianca
Panama City — Bogota
3h 51m stop
08:45 — 12:45 AV36 Avianca
Bogota — Miami
2h 45m stop
18:25 — 20:58 NK1042 Spirit Airlines
Miami — Louisville
14h 38m
including layover
Find flight
from$288
03:19 — 17:27
03:19 — 04:54 AV41 Avianca
Panama City — Bogota
3h 51m stop
08:45 — 12:45 AV36 Avianca
Bogota — Miami
2h 6m stop
14:51 — 17:27 G41181 Allegiant Air
Miami — Louisville
14h 8m
including layover
Find flight
from$569
13:30 — 09:12
+2 days
13:30 — 13:45 AV642 Avianca
Panama City — San Jose
24h 56m stop
14:41 — 19:05 NK1310 Spirit Airlines
San Jose — Orlando
11h 55m stop
07:00 — 09:12 NK142 Spirit Airlines
Orlando — Louisville
43h 42m
including layover
Find flight
from$403
13:30 — 20:39
+2 days
13:30 — 13:45 AV642 Avianca
Panama City — San Jose
24h 56m stop
14:41 — 19:05 NK1310 Spirit Airlines
San Jose — Sanford
23h 21m stop
18:26 — 20:39 G42902 Allegiant Air
Sanford — Louisville
55h 9m
including layover
Find flight
from$417
15:20 — 09:12
+2 days
15:20 — 15:56 CM116 Compania Panamena de Aviacion
Panama City — San Jose
22h 45m stop
14:41 — 19:05 NK1310 Spirit Airlines
San Jose — Orlando
11h 55m stop
07:00 — 09:12 NK142 Spirit Airlines
Orlando — Louisville
41h 52m
including layover
Find flight
from$422
15:20 — 20:39
+2 days
15:20 — 15:56 CM116 Compania Panamena de Aviacion
Panama City — San Jose
22h 45m stop
14:41 — 19:05 NK1310 Spirit Airlines
San Jose — Sanford
23h 21m stop
18:26 — 20:39 G42902 Allegiant Air
Sanford — Louisville
53h 19m
including layover
Find flight
from$436
21:39 — 09:12
+2 days
21:39 — 22:06 CM162 Compania Panamena de Aviacion
Panama City — San Jose
16h 35m stop
14:41 — 19:05 NK1310 Spirit Airlines
San Jose — Orlando
11h 55m stop
07:00 — 09:12 NK142 Spirit Airlines
Orlando — Louisville
35h 33m
including layover
Find flight
from$443
21:39 — 20:39
+2 days
21:39 — 22:06 CM162 Compania Panamena de Aviacion
Panama City — San Jose
16h 35m stop
14:41 — 19:05 NK1310 Spirit Airlines
San Jose — Sanford
23h 21m stop
18:26 — 20:39 G42902 Allegiant Air
Sanford — Louisville
47h
including layover
Find flight
from$457
21:55 — 09:12
+2 days
21:55 — 23:25 AV57 Avianca
Panama City — Bogota
10h 50m stop
10:15 — 14:32 LA4406 LAN Airlines
Bogota — Orlando
16h 28m stop
07:00 — 09:12 NK142 Spirit Airlines
Orlando — Louisville
35h 17m
including layover
Find flight
from$554
21:55 — 09:12
+2 days
21:55 — 23:25 AV57 Avianca
Panama City — Bogota
9h 20m stop
08:45 — 13:00 AV216 Avianca
Bogota — Orlando
18h stop
07:00 — 09:12 NK142 Spirit Airlines
Orlando — Louisville
35h 17m
including layover
Find flight
from$588
21:55 — 09:12
+2 days
21:55 — 23:25 AV57 Avianca
Panama City — Bogota
8h 35m stop
08:00 — 12:15 AV28 Avianca
Bogota — Orlando
18h 45m stop
07:00 — 09:12 NK142 Spirit Airlines
Orlando — Louisville
35h 17m
including layover
Find flight
from$605
22:26 — 17:57
+2 days
22:30 — 00:06 CM430 Compania Panamena de Aviacion
Panama City — Bogota
14h 56m stop
14:57 — 19:05 NK400 Spirit Airlines
Bogota — Miami
20h 25m stop
16:19 — 18:52 NK1042 Spirit Airlines
Miami — Louisville
43h 31m
including layover
Find flight
from$353
22:26 — 09:12
+2 days
22:26 — 00:02 CM430 Compania Panamena de Aviacion
Panama City — Bogota
10h 13m stop
10:15 — 14:32 LA4406 LAN Airlines
Bogota — Orlando
16h 28m stop
07:00 — 09:12 NK142 Spirit Airlines
Orlando — Louisville
34h 46m
including layover
Find flight
from$584
22:26 — 09:12
+2 days
22:26 — 00:02 CM430 Compania Panamena de Aviacion
Panama City — Bogota
8h 43m stop
08:45 — 13:00 AV216 Avianca
Bogota — Orlando
18h stop
07:00 — 09:12 NK142 Spirit Airlines
Orlando — Louisville
34h 46m
including layover
Find flight
from$618
*Departure and arrival times - local. Updated on February 22, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Panama City to Louisville depends on and how to choose the most interesting flight option for you.

Distance between Panama City and Louisville is 3298 miles. Time difference between the cities is 0h. Airplanes depart 03:19 to 22:26 from 2 Panama City airports and arrive 03:19 to 22:26 to 3 Louisville airports. Average flight time is 35h 25m.

  • The fastest flight 14h 8m
  • Average flight time 35h 25m
  • The earliest flight 03:19
  • The latest flight 22:26
  • Distance 2050 ml

The cheapest months to travel to Louisville are december (from 288 $), february (from 339 $), november (from 353 $).

What is the lowest airfare Panama City to Louisville?

The cheapest plane ticket found by our users is $288. This airfare is for economy class on one-way AV41 flight by Avianca for February 21, 2025 which leaves Tocumen in Panama City at 03:19 am and arrives at Louisville Standiford Field at 17:57.

Economy class
$288
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Business class
?
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First class
?
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Popular Airlines on the Route

The flight Panama City — Louisville is served by 2 regular airlines . Most of the flights on this route are operated by Avianca - 7 departures per week at the price of from $ 288 . And the most expensive tickets are offered by Compania Panamena de Aviacion airline - from $ 618.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 14 flights with layovers on the route. The fastest connecting flight is AV41 by Avianca takes 14h 8m and the cheapest is AV41 by Avianca for $288.

  • AV - Avianca
    from $288
    Find
  • CM - Compania Panamena de Aviacion
    from $353
    Find
See more connecting flights

Airports

You can fly from Panama City to Louisville from 2 airports (Tocumen, Paitilla).

Panama City airports

  • Tocumen-PTY
    from $288
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  • Paitilla-PAC
    Find

Louisville airports

  • Standiford Field-SDF
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  • Intercontinental-LJC
    Find
  • Bowman Field-LOU
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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