Cheap Flights from Manchester to San Francisco, CA from $322

On Cheapflightsplus.com you will find 1000 connecting flights from Manchester to San Francisco. You can compare airfare deals from 28 airlines and multiple travel sites from $322, book and save on cheap plane tickets and last minute offers. Also check out MAN-SFO flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Manchester to San Francisco depends on and how to choose the most interesting flight option for you.

Distance between Manchester and San Francisco is 8380 miles. Time difference between the cities is 8h. Airplanes depart 05:55 to 23:15 from 1 Manchester airport and arrive 05:55 to 23:15 to 3 San Francisco airports. Average flight time is 28h 41m.

  • The fastest flight 13h 5m
  • Average flight time 28h 41m
  • The earliest flight 05:55
  • The latest flight 23:15
  • Distance 5208 ml

The cheapest months to travel to San Francisco are june (from 322 $), october (from 382 $), may (from 393 $).

The most expensive months are december (from 2 128 $), february (from 1 949 $), january (from 1 924 $).

What is the lowest airfare Manchester to San Francisco?

The cheapest plane ticket found by our users is $322. This airfare is for economy class on one-way U24646 flight by EasyJet for June 5, 2025 which leaves Manchester Int. in Manchester at 20:25 am and arrives at San Francisco San Francisco at 19:48.

Economy class
$322
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Business class
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First class
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Flight Schedule Manchester to San Francisco (California)

12:05 — 20:50
16h 45m flight time
Find flight
from$440
20:25 — 23:00 Manchester — Paris
U24646 EasyJet
3h 55m stop
18:30 — 20:50 Paris — San Francisco
TX6710 Air Caraibes
14:15 — 13:50+1day
31h 35m flight time
Find flight
from$487
14:15 — 16:50 Manchester — Paris
AF1069 Air France
18h 40m stop
11:30 — 13:50 Paris — San Francisco
BF714 Bluebird Cargo
14:40 — 17:25+1day
34h 45m flight time
Find flight
from$423
14:40 — 18:00 Manchester — Barcelona
U27204 EasyJet
19h 20m stop
13:20 — 17:25 Barcelona — San Francisco
VY9791 Vueling
17:45 — 13:50+1day
28h 5m flight time
Find flight
from$456
17:45 — 20:20 Manchester — Paris
AF1169 Air France
15h 10m stop
11:30 — 13:50 Paris — San Francisco
BF714 Bluebird Cargo
17:55 — 13:35+1day
27h 40m flight time
Find flight
from$449
17:55 — 20:50 Manchester — Lisbon
TP1313 TAP Portugal
12h 10m stop
12:20 — 16:50 Lisbon — San Francisco
TP237 TAP Portugal
18:10 — 18:10+1day
32h flight time
Find flight
from$474
18:10 — 21:35 Manchester — Barcelona
FR5271 Ryanair
16h 30m stop
14:05 — 18:10 Barcelona — San Francisco
AY5397 Finnair
18:35 — 13:50+1day
27h 15m flight time
Find flight
from$395
18:35 — 21:10 Manchester — Paris
U22117 EasyJet
14h 20m stop
11:30 — 13:50 Paris — San Francisco
BF714 Bluebird Cargo
18:35 — 13:50+1day
27h 15m flight time
Find flight
from$465
18:35 — 21:10 Manchester — Paris
U22117 EasyJet
14h 20m stop
11:30 — 13:50 Paris — San Francisco
TX6714 Air Caraibes
18:55 — 16:10+1day
29h 15m flight time
Find flight
from$472
18:55 — 22:40 Manchester — Madrid
U22049 EasyJet
13h 55m stop
12:35 — 16:10 Madrid — San Francisco
AY5557 Finnair
19:00 — 13:50+1day
26h 50m flight time
Find flight
from$450
13:50 — 16:20 Manchester — Paris
U22107 EasyJet
13h 55m stop
11:30 — 13:50 Paris — San Francisco
BF714 Bluebird Cargo
19:10 — 20:50+1day
33h 40m flight time
Find flight
from$451
18:40 — 21:15 Manchester — Paris
U22109 EasyJet
20h 45m stop
18:30 — 20:50 Paris — San Francisco
BF710 Bluebird Cargo
19:10 — 20:50+1day
33h 40m flight time
Find flight
from$467
18:40 — 21:15 Manchester — Paris
U22109 EasyJet
20h 45m stop
18:30 — 20:50 Paris — San Francisco
TX6710 Air Caraibes
19:15 — 16:10+1day
28h 55m flight time
Find flight
from$482
19:15 — 22:45 Manchester — Madrid
I21892 Iberia Express
13h 50m stop
12:35 — 16:10 Madrid — San Francisco
AY5557 Finnair
19:20 — 13:50+1day
26h 30m flight time
Find flight
from$389
19:20 — 21:55 Manchester — Paris
U22109 EasyJet
13h 35m stop
11:30 — 13:50 Paris — San Francisco
BF714 Bluebird Cargo
19:20 — 13:50+1day
26h 30m flight time
Find flight
from$459
19:20 — 21:55 Manchester — Paris
U22109 EasyJet
13h 35m stop
11:30 — 13:50 Paris — San Francisco
TX6714 Air Caraibes
Full flight schedule will help you in detecting at what time planes fly from Manchester to San Francisco. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on October 14, 2025.

Popular Airlines on the Route

The flight Manchester — San Francisco is served by 28 regular airlines and 8 low-cost airlines. Most of the flights on this route are operated by Vueling - 37 departures per week at the price of from $ 412 . And the most expensive tickets are offered by Vueling airline - from $ 867.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 1000 flights with layovers on the route. The fastest connecting flight is FR559 by Ryanair takes 13h 5m and the cheapest is U24646 by EasyJet for $322.

  • VY - Vueling
    from $412
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  • FI - Icelandair
    from $802
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  • LS - Jet2.com
    from $403
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  • I2 - Iberia Express
    from $440
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  • FR - Ryanair
    from $382
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  • LX - SWISS International Air Lines
    from $675
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  • DY - Norwegian
    from $416
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  • SK - SAS
    from $393
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  • IB - Iberia
    from $464
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  • KL - KLM
    from $509
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  • EI - Aer Lingus
    from $465
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  • AF - Air France
    from $423
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See more connecting flights

Airports

You can fly from Manchester to San Francisco from 1 airports (Manchester Int.).

Manchester airports

  • Manchester Int.-MAN
    from $322
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San Francisco airports

  • San Francisco-SFO
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  • Embarkadero-EMB
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  • China Basin Heliport-JCC
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How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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