Cheap Flights from Manchester to San Francisco, CA from $384

On Cheapflightsplus.com you will find 1000 connecting flights from Manchester to San Francisco. You can compare airfare deals from 28 airlines and multiple travel sites from $384, book and save on cheap plane tickets and last minute offers. Also check out MAN-SFO flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Manchester to San Francisco Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $384 (one-way), $659 (round-trip).
Direct flights
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Check prices for return flight
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Full flight schedule will help you in detecting at what time planes fly from Manchester to San Francisco. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
12:05 — 20:50
20:25 — 23:00 U24646 EasyJet
Manchester — Paris
3h 55m stop
18:30 — 20:50 TX6710 Air Caraibes
Paris — San Francisco
16h 45m
including layover
Find flight
from$441
14:15 — 13:50
+1 day
14:15 — 16:50 AF1069 Air France
Manchester — Paris
18h 40m stop
11:30 — 13:50 BF714 Bluebird Cargo
Paris — San Francisco
31h 35m
including layover
Find flight
from$489
14:40 — 17:25
+1 day
14:40 — 18:00 U27204 EasyJet
Manchester — Barcelona
19h 20m stop
13:20 — 17:25 VY9791 Vueling
Barcelona — San Francisco
34h 45m
including layover
Find flight
from$424
17:45 — 13:50
+1 day
17:45 — 20:20 AF1169 Air France
Manchester — Paris
15h 10m stop
11:30 — 13:50 BF714 Bluebird Cargo
Paris — San Francisco
28h 5m
including layover
Find flight
from$457
17:55 — 13:35
+1 day
17:55 — 20:50 TP1313 TAP Portugal
Manchester — Lisbon
12h 10m stop
12:20 — 16:50 TP237 TAP Portugal
Lisbon — San Francisco
27h 40m
including layover
Find flight
from$450
18:10 — 18:10
+1 day
18:10 — 21:35 FR5271 Ryanair
Manchester — Barcelona
16h 30m stop
14:05 — 18:10 AY5397 Finnair
Barcelona — San Francisco
32h
including layover
Find flight
from$476
18:35 — 13:50
+1 day
18:35 — 21:10 U22117 EasyJet
Manchester — Paris
14h 20m stop
11:30 — 13:50 BF714 Bluebird Cargo
Paris — San Francisco
27h 15m
including layover
Find flight
from$396
18:35 — 13:50
+1 day
18:35 — 21:10 U22117 EasyJet
Manchester — Paris
14h 20m stop
11:30 — 13:50 TX6714 Air Caraibes
Paris — San Francisco
27h 15m
including layover
Find flight
from$466
18:55 — 16:10
+1 day
18:55 — 22:40 U22049 EasyJet
Manchester — Madrid
13h 55m stop
12:35 — 16:10 AY5557 Finnair
Madrid — San Francisco
29h 15m
including layover
Find flight
from$473
19:00 — 13:50
+1 day
13:50 — 16:20 U22107 EasyJet
Manchester — Paris
13h 55m stop
11:30 — 13:50 BF714 Bluebird Cargo
Paris — San Francisco
26h 50m
including layover
Find flight
from$452
19:10 — 20:50
+1 day
18:40 — 21:15 U22109 EasyJet
Manchester — Paris
20h 45m stop
18:30 — 20:50 BF710 Bluebird Cargo
Paris — San Francisco
33h 40m
including layover
Find flight
from$452
19:10 — 20:50
+1 day
18:40 — 21:15 U22109 EasyJet
Manchester — Paris
20h 45m stop
18:30 — 20:50 TX6710 Air Caraibes
Paris — San Francisco
33h 40m
including layover
Find flight
from$469
19:15 — 16:10
+1 day
19:15 — 22:45 I21892 Iberia Express
Manchester — Madrid
13h 50m stop
12:35 — 16:10 AY5557 Finnair
Madrid — San Francisco
28h 55m
including layover
Find flight
from$483
19:20 — 13:50
+1 day
19:20 — 21:55 U22109 EasyJet
Manchester — Paris
13h 35m stop
11:30 — 13:50 BF714 Bluebird Cargo
Paris — San Francisco
26h 30m
including layover
Find flight
from$391
19:20 — 13:50
+1 day
19:20 — 21:55 U22109 EasyJet
Manchester — Paris
13h 35m stop
11:30 — 13:50 TX6714 Air Caraibes
Paris — San Francisco
26h 30m
including layover
Find flight
from$460
*Departure and arrival times - local. Updated on September 14, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Manchester to San Francisco depends on and how to choose the most interesting flight option for you.

Distance between Manchester and San Francisco is 8380 miles. Time difference between the cities is 8h. Airplanes depart 05:55 to 23:15 from 1 Manchester airport and arrive 05:55 to 23:15 to 3 San Francisco airports. Average flight time is 28h 41m.

  • The fastest flight 13h 5m
  • Average flight time 28h 41m
  • The earliest flight 05:55
  • The latest flight 23:15
  • Distance 5208 ml

Popular Airlines on the Route

The flight Manchester — San Francisco is served by 28 regular airlines and 8 low-cost airlines. Most of the flights on this route are operated by Vueling - 37 departures per week at the price of from $ 413 . And the most expensive tickets are offered by Aer Lingus airline - from $ 1659.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 1000 flights with layovers on the route. The fastest connecting flight is FR559 by Ryanair takes 13h 5m.

  • VY - Vueling
    from $413
    Find
  • FI - Icelandair
    from $804
    Find
  • LS - Jet2.com
    from $405
    Find
  • I2 - Iberia Express
    from $441
    Find
  • FR - Ryanair
    from $384
    Find
  • LX - SWISS International Air Lines
    from $677
    Find
  • DY - Norwegian
    from $417
    Find
  • SK - SAS
    from $395
    Find
  • IB - Iberia
    from $466
    Find
  • KL - KLM
    from $511
    Find
  • EI - Aer Lingus
    from $467
    Find
  • AF - Air France
    from $425
    Find
See more connecting flights

Airports

You can fly from Manchester to San Francisco from 1 airports (Manchester Int.).

Manchester airports

  • Manchester Int.-MAN
    from $323
    Find

San Francisco airports

  • San Francisco-SFO
    Find
  • Embarkadero-EMB
    Find
  • China Basin Heliport-JCC
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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