Cheap Flights from Manchester to Knoxville, TN from $448

On Cheapflightsplus.com you will find 44 connecting flights from Manchester to Knoxville. You can compare airfare deals from 8 airlines and multiple travel sites from $448, book and save on cheap plane tickets and last minute offers. Also check out MAN-TYS flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Manchester to Knoxville Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $448 (one-way), $768 (round-trip).
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Full flight schedule will help you in detecting at what time planes fly from Manchester to Knoxville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
06:00 — 14:16
+1 day
06:00 — 08:55 U22259 EasyJet
Manchester — Reykjavik
8h 5m stop
17:00 — 17:45 FI631 Icelandair
Reykjavik — Boston
17h 50m stop
11:35 — 14:16 G43039 Allegiant Air
Boston — Knoxville
37h 16m
including layover
Find flight
from$693
06:00 — 21:53
06:10 — 07:25 BA1371 British Airways
Manchester — London
6h 55m stop
14:10 — 17:00 BA1542 British Airways
London — Chicago
2h 10m stop
15:47 — 18:26 BA5412 British Airways
Chicago — Knoxville
20h 53m
including layover
Find flight
from$1740
07:50 — 20:31
07:40 — 08:55 BA1391 British Airways
Manchester — London
4h 5m stop
13:10 — 16:20 BA67 British Airways
London — Philadelphia
2h 10m stop
18:50 — 20:50 BA6890 British Airways
Philadelphia — Knoxville
17h 41m
including layover
Find flight
from$1740
07:50 — 21:53
07:50 — 09:05 BA1391 British Airways
Manchester — London
5h 5m stop
14:10 — 17:00 BA1542 British Airways
London — Chicago
2h 10m stop
15:47 — 18:26 BA5412 British Airways
Chicago — Knoxville
19h 3m
including layover
Find flight
from$1740
09:00 — 20:31
08:55 — 10:10 BA1387 British Airways
Manchester — London
2h 55m stop
13:10 — 16:20 BA67 British Airways
London — Philadelphia
2h 10m stop
18:50 — 20:50 BA6890 British Airways
Philadelphia — Knoxville
16h 31m
including layover
Find flight
from$1740
09:00 — 21:53
09:00 — 10:15 BA1387 British Airways
Manchester — London
1h 40m stop
11:55 — 14:45 BA1546 British Airways
London — Chicago
4h 15m stop
19:00 — 21:53 BA5412 British Airways
Chicago — Knoxville
17h 53m
including layover
Find flight
from$1740
10:15 — 20:31
09:45 — 11:00 BA1389 British Airways
Manchester — London
1h 40m stop
13:10 — 16:20 BA67 British Airways
London — Philadelphia
2h 10m stop
18:50 — 20:50 BA6890 British Airways
Philadelphia — Knoxville
15h 16m
including layover
Find flight
from$1740
10:15 — 21:53
09:50 — 11:05 BA1389 British Airways
Manchester — London
2h 40m stop
14:10 — 17:00 BA1542 British Airways
London — Chicago
2h 10m stop
15:47 — 18:26 BA5412 British Airways
Chicago — Knoxville
16h 38m
including layover
Find flight
from$1740
11:50 — 21:49
+1 day
11:50 — 13:05 BA1393 British Airways
Manchester — London
22h 50m stop
11:55 — 14:45 BA1546 British Airways
London — Chicago
4h 25m stop
19:10 — 21:49 BA5412 British Airways
Chicago — Knoxville
38h 59m
including layover
Find flight
from$1740
11:55 — 14:16
+1 day
11:55 — 14:45 FI441 Icelandair
Manchester — Reykjavik
2h 15m stop
17:00 — 17:45 FI631 Icelandair
Reykjavik — Boston
17h 50m stop
11:35 — 14:16 G43039 Allegiant Air
Boston — Knoxville
31h 21m
including layover
Find flight
from$807
12:25 — 14:16
+1 day
12:25 — 13:40 EI3325 Aer Lingus
Manchester — Dublin
3h 5m stop
16:45 — 18:59 EI137 Aer Lingus
Dublin — Boston
16h 36m stop
11:35 — 14:16 G43039 Allegiant Air
Boston — Knoxville
30h 51m
including layover
Find flight
from$861
13:55 — 14:16
+1 day
13:55 — 14:55 EI205 Aer Lingus
Manchester — Dublin
1h 50m stop
16:45 — 18:59 EI137 Aer Lingus
Dublin — Boston
16h 36m stop
11:35 — 14:16 G43039 Allegiant Air
Boston — Knoxville
29h 21m
including layover
Find flight
from$983
14:15 — 12:38
+1 day
14:15 — 17:20 EI45 Aer Lingus
Manchester — New York
2h 36m stop
19:56 — 23:14 EI5314 Aer Lingus
New York — Miami
11h 15m stop
10:29 — 12:38 G41428 Allegiant Air
Miami — Knoxville
27h 23m
including layover
Find flight
from$1884
15:05 — 20:31
+1 day
14:45 — 15:55 BA1399 British Airways
Manchester — London
20h 55m stop
13:10 — 16:20 BA67 British Airways
London — Philadelphia
2h 10m stop
18:50 — 20:50 BA6890 British Airways
Philadelphia — Knoxville
34h 26m
including layover
Find flight
from$1740
15:05 — 21:49
+1 day
15:05 — 16:15 BA1399 British Airways
Manchester — London
19h 40m stop
11:55 — 14:45 BA1546 British Airways
London — Chicago
4h 25m stop
19:10 — 21:49 BA5412 British Airways
Chicago — Knoxville
35h 44m
including layover
Find flight
from$1740
16:40 — 12:46
+2 days
16:40 — 19:30 U22261 EasyJet
Manchester — Reykjavik
20h 30m stop
16:00 — 17:00 OG111 Air Onix
Reykjavik — Boston
17h 5m stop
10:05 — 12:46 G41414 Allegiant Air
Boston — Knoxville
49h 6m
including layover
Find flight
from$448
17:05 — 21:49
+1 day
17:15 — 18:20 BA1403 British Airways
Manchester — London
20h stop
14:10 — 17:00 BA1542 British Airways
London — Chicago
2h 20m stop
15:47 — 18:26 BA5412 British Airways
Chicago — Knoxville
33h 44m
including layover
Find flight
from$1740
17:15 — 12:46
+2 days
17:15 — 18:25 EI3327 Aer Lingus
Manchester — Dublin
17h 10m stop
11:35 — 13:50 EI133 Aer Lingus
Dublin — Boston
20h 15m stop
10:05 — 12:46 G41414 Allegiant Air
Boston — Knoxville
48h 31m
including layover
Find flight
from$828
19:45 — 12:46
+2 days
19:45 — 20:45 EI213 Aer Lingus
Manchester — Dublin
14h 50m stop
11:35 — 13:50 EI133 Aer Lingus
Dublin — Boston
20h 15m stop
10:05 — 12:46 G41414 Allegiant Air
Boston — Knoxville
46h 1m
including layover
Find flight
from$847
20:05 — 20:31
+1 day
19:20 — 20:25 BA1405 British Airways
Manchester — London
13h 5m stop
10:15 — 13:20 BA1588 British Airways
London — Philadelphia
5h 5m stop
18:50 — 20:50 BA6890 British Airways
Philadelphia — Knoxville
29h 26m
including layover
Find flight
from$1740
20:20 — 12:46
+2 days
20:20 — 23:10 D83523 Djibouti Airlines
Manchester — Copenhagen
14h 5m stop
13:15 — 15:50 SK927 SAS
Copenhagen — Boston
18h 15m stop
10:05 — 12:46 G41414 Allegiant Air
Boston — Knoxville
45h 26m
including layover
Find flight
from$752
21:30 — 11:50
+2 days
21:30 — 22:35 BA1373 British Airways
Manchester — London
15h 25m stop
14:00 — 18:30 Z0783 Z0
London — Sanford
15h 42m stop
10:12 — 11:50 G43039 Allegiant Air
Sanford — Knoxville
43h 20m
including layover
Find flight
from$555
21:30 — 20:31
+1 day
16:00 — 17:10 BA1373 British Airways
Manchester — London
11h 40m stop
10:15 — 13:20 BA1588 British Airways
London — Philadelphia
5h 5m stop
18:50 — 20:50 BA6890 British Airways
Philadelphia — Knoxville
28h 1m
including layover
Find flight
from$1740
*Departure and arrival times - local. Updated on February 5, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Manchester to Knoxville depends on and how to choose the most interesting flight option for you.

Distance between Manchester and Knoxville is 6380 miles. Time difference between the cities is 5h. Airplanes depart 06:00 to 21:30 from 1 Manchester airport and arrive 06:00 to 21:30 to 1 Knoxville airport. Average flight time is 30h 30m.

  • The fastest flight 15h 16m
  • Average flight time 30h 30m
  • The earliest flight 06:00
  • The latest flight 21:30
  • Distance 3965 ml

The cheapest months to travel to Knoxville are february (from 448 $), december (from 2 998 $), november (from 3 088 $).

The most expensive months are january (from 5 439 $), november (from 3 088 $), december (from 2 998 $).

What is the lowest airfare Manchester to Knoxville?

The cheapest plane ticket found by our users is $448. This airfare is for economy class on one-way U22261 flight by EasyJet for February 21, 2025 which leaves Manchester Int. in Manchester at 16:40 am and arrives at Knoxville Mc Ghee Tyson at 12:46.

Economy class
$448
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Business class
?
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First class
?
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Popular Airlines on the Route

The flight Manchester — Knoxville is served by 8 regular airlines and 1 low-cost airline. Most of the flights on this route are operated by Icelandair - 1 departures per week at the price of from $ 807 . And the most expensive tickets are offered by British Airways airline - from $ 5439.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 44 flights with layovers on the route. The fastest connecting flight is BA1389 by British Airways takes 15h 16m and the cheapest is U22261 by EasyJet for $448.

  • FI - Icelandair
    from $807
    Find
  • D8 - Djibouti Airlines
    from $752
    Find
  • EI - Aer Lingus
    from $828
    Find
  • AY - Finnair
    from $1840
    Find
  • LH - Lufthansa
    from $3082
    Find
  • U2 - EasyJet
    from $448
    Find
  • VS - Virgin Atlantic Airways
    from $1812
    Find
  • BA - British Airways
    from $555
    Find
See more connecting flights

Airports

You can fly from Manchester to Knoxville from 1 airports (Manchester Int.).

Manchester airports

  • Manchester Int.-MAN
    from $448
    Find

Knoxville airports

  • Mc Ghee Tyson-TYS
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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