Cheap Flights from Louisville, KY to Fort Myers, FL from $50

Return flight: Fort Myers – Louisville
Page navigation
Price Calendar Cheap Flights Flights Schedule

On Cheapflightsplus.com you will find 1 direct and 256 connecting flights from Louisville to Fort Myers. You can compare airfare deals from 5 airlines and multiple travel sites from $50, book and save on cheap plane tickets and last minute offers. Also check out SDF-RSW flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Louisville to Fort Myers Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $50 (one-way), $86 (round-trip).
Direct flights
  • Check to choose departure date Check to choose departure date
Check prices for return flight
Find flights

Best Flights from Louisville to Fort Myers Today

Take a look at the list of non stop flights and flights with layovers from Louisville to Fort Myers with the lowest price of $50. The fastest direct flight takes 2h 28m and the fastest connecting – 4h 53m.
Price Departure Arrival Flight Duration Airline Flight
from $50
Find flight
20:44
Louisville
Standiford Field
 23:12
Fort Myers
Southwest Florida Reg
 2h 28m Mexicana
MX753
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on September 15, 2025
Full flight schedule will help you in detecting at what time planes fly from Louisville to Fort Myers. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
06:00 — 10:53
06:00 — 07:35 UA6358 United Airlines
Louisville — Washington D.C.
40m stop
08:20 — 10:58 UA1406 United Airlines
Washington D.C. — Fort Myers
4h 53m
including layover
Find flight
from$185
06:15 — 14:04
06:15 — 08:30 UA3594 United Airlines
Louisville — Newark
2h 30m stop
11:00 — 14:04 UA1884 United Airlines
Newark — Fort Myers
7h 49m
including layover
Find flight
from$188
07:00 — 13:23
07:00 — 07:38 UA3422 United Airlines
Louisville — Chicago
1h 42m stop
09:20 — 13:23 UA1036 United Airlines
Chicago — Fort Myers
6h 23m
including layover
Find flight
from$188
07:15 — 16:14
07:15 — 08:45 UA6266 United Airlines
Louisville — Houston
3h 55m stop
12:40 — 16:14 UA2722 United Airlines
Houston — Fort Myers
8h 59m
including layover
Find flight
from$185
09:35 — 16:14
09:35 — 11:05 UA6108 United Airlines
Louisville — Houston
1h 35m stop
12:40 — 16:14 UA2722 United Airlines
Houston — Fort Myers
6h 39m
including layover
Find flight
from$185
11:04 — 19:04
11:04 — 12:22 NK2795 Spirit Airlines
Louisville — Detroit
3h 54m stop
16:16 — 19:04 NK2494 Spirit Airlines
Detroit — Fort Myers
8h
including layover
Find flight
from$106
12:00 — 19:00
+1 day
12:00 — 13:24 NK2459 Spirit Airlines
Louisville — Atlanta
17h 21m stop
06:45 — 08:42 NK1156 Spirit Airlines
Atlanta — Detroit
7h 29m stop
16:11 — 19:00 NK2335 Spirit Airlines
Detroit — Fort Myers
31h
including layover
Find flight
from$131
12:00 — 19:00
+1 day
12:00 — 13:24 NK2459 Spirit Airlines
Louisville — Atlanta
20h 4m stop
09:28 — 11:27 NK1103 Spirit Airlines
Atlanta — Detroit
4h 44m stop
16:11 — 19:00 NK2335 Spirit Airlines
Detroit — Fort Myers
31h
including layover
Find flight
from$131
12:24 — 19:00
+1 day
12:24 — 14:51 G42147 Allegiant Air
Louisville — Miami
18h 8m stop
08:59 — 11:58 NK380 Spirit Airlines
Miami — Detroit
4h 13m stop
16:11 — 19:00 NK2335 Spirit Airlines
Detroit — Fort Myers
30h 36m
including layover
Find flight
from$185
15:07 — 19:04
+1 day
15:07 — 17:09 NK2159 Spirit Airlines
Louisville — Tampa
1h 6m stop
18:15 — 20:59 NK2740 Spirit Airlines
Tampa — Detroit
19h 17m stop
16:16 — 19:04 NK2494 Spirit Airlines
Detroit — Fort Myers
27h 57m
including layover
Find flight
from$178
16:22 — 19:00
+1 day
16:22 — 18:42 NK2733 Spirit Airlines
Louisville — New York
18h 13m stop
12:55 — 14:56 NK382 Spirit Airlines
New York — Detroit
1h 15m stop
16:11 — 19:00 NK2335 Spirit Airlines
Detroit — Fort Myers
26h 38m
including layover
Find flight
from$179
16:22 — 19:00
+1 day
16:22 — 18:42 NK2733 Spirit Airlines
Louisville — New York
16h 11m stop
10:53 — 12:52 NK2494 Spirit Airlines
New York — Detroit
3h 19m stop
16:11 — 19:00 NK2335 Spirit Airlines
Detroit — Fort Myers
26h 38m
including layover
Find flight
from$179
17:39 — 10:36
+1 day
10:04 — 11:06 SY1792 Sun Country Airlines
Louisville — Minneapolis
11h 37m stop
06:18 — 10:36 SY383 Sun Country Airlines
Minneapolis — Fort Myers
16h 57m
including layover
Find flight
from$173
17:45 — 19:00
+1 day
17:45 — 19:25 NK3883 Spirit Airlines
Louisville — Detroit
20h 46m stop
16:11 — 19:00 NK2335 Spirit Airlines
Detroit — Fort Myers
25h 15m
including layover
Find flight
from$129
20:44 — 23:12
20:44 — 23:12 MX753 Mexicana
Louisville — Fort Myers
2h 28m
Find flight
from$50
*Departure and arrival times - local. Updated on September 15, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Louisville to Fort Myers depends on and how to choose the most interesting flight option for you.

Distance between Louisville and Fort Myers is 1347 miles. Time difference between the cities is 0h. Airplanes depart 05:03 to 20:58 from 3 Louisville airports and arrive 05:03 to 20:58 to 2 Fort Myers airports. Average flight time is 2h 28m.

  • The fastest flight 2h 28m
  • Average flight time 2h 28m
  • The earliest flight 05:03
  • The latest flight 20:58
  • Distance 837 ml

The cheapest months to travel to Fort Myers are july (from 50 $), august (from 50 $), october (from 188 $).

The most expensive months are september (from 207 $), october (from 188 $), august (from 50 $).

What is the lowest airfare Louisville to Fort Myers?

The cheapest plane ticket found by our users is $50. This airfare is for economy class on one-way MX753 flight by Mexicana for July 6, 2025 which leaves Standiford Field in Louisville at 20:44 am and arrives at Fort Myers Southwest Florida Reg at 23:12.

Economy class
$50
Find
Business class
?
Find
First class
?
Find

Popular Airlines on the Route

The flight Louisville — Fort Myers is served by 5 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Sun Country Airlines - 3 departures per week at the price of from $ 173 . And the most expensive tickets are offered by United Airlines airline - from $ 6330.

Direct flights

There are 1 nonstop flights on the route. The fastest direct flight is MX753 by Mexicana takes 2h 28m and the cheapest is MX753 by Mexicana for $50.

  • MX - Mexicana
    from $50
    Find
See more direct flights

Connecting Flights

There are 256 flights with layovers on the route. The fastest connecting flight is UA6358 by United Airlines takes 4h 53m and the cheapest is MX753 by Mexicana for $106.

  • SY - Sun Country Airlines
    from $173
    Find
  • MX - Mexicana
    from $196
    Find
  • UA - United Airlines
    from $185
    Find
  • NK - Spirit Airlines
    from $106
    Find
  • G4 - Allegiant Air
    from $185
    Find
See more connecting flights

Airports

You can fly from Louisville to Fort Myers from 3 airports (Standiford Field, Intercontinental, Bowman Field).

Louisville airports

  • Standiford Field-SDF
    from $50
    Find
  • Intercontinental-LJC
    Find
  • Bowman Field-LOU
    Find

Fort Myers airports

  • Southwest Florida Reg-RSW
    Find
  • Page Field-FMY
    Find

Airplanes

There are flights to Fort Myers from Louisville by 5 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Louisville

You may also consider searching for discounted plane tickets to some other popular places from Louisville within United States.

Top International Destinations from Louisville

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back