Cheap Flights from Fort Myers, FL to Louisville, KY from $54

One way Round trip

Adults

Children under 12

Infants under 2 without place

Economy

Business

First

done

Return flight: Louisville – Fort Myers

Page navigation

Price Calendar Cheap Flights Flights Schedule

On Cheapflightsplus.com you will find 1 direct and 228 connecting flights from Fort Myers to Louisville. You can compare airfare deals from 5 airlines and multiple travel sites from $54, book and save on cheap plane tickets and last minute offers. Also check out RSW-SDF flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Fort Myers to Louisville Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $54 (one-way), $93 (round-trip).

Direct flights

Check to choose departure date Check to choose departure date

Check prices for return flight

Find flights

Best Flights from Fort Myers to Louisville Today

Take a look at the list of non stop flights and flights with layovers from Fort Myers to Louisville with the lowest price of $54. The fastest direct flight takes 2h 29m and the fastest connecting – 5h 38m.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $54 Find flight	17:35 Fort Myers Southwest Florida Reg	20:04 Louisville Standiford Field	2h 29m	Mexicana	MX752
from $119 Find flight	07:05 Fort Myers Southwest Florida Reg	15:19 Louisville Standiford Field	8h 14m layover 4h 40m - Raleigh	Mexicana	MX744 MX330
from $175 Find flight	11:25 Fort Myers Southwest Florida Reg	08:55+1 день Louisville Standiford Field	21h 30m layover 16h 6m - Minneapolis	Sun Country Airlines	SY384 SY1791
from $175 Find flight	06:00 Fort Myers Southwest Florida Reg	08:55+1 день Louisville Standiford Field	26h 55m layover 21h 31m - Minneapolis	Sun Country Airlines	SY390 SY1791
from $202 Find flight	14:30 Fort Myers Southwest Florida Reg	20:33 Louisville Standiford Field	6h 3m layover 1h 15m - Chicago	United Airlines	UA1967 UA3598
from $202 Find flight	07:00 Fort Myers Southwest Florida Reg	13:33 Louisville Standiford Field	6h 33m layover 1h 28m - Houston	United Airlines	UA1809 UA6150
from $202 Find flight	15:30 Fort Myers Southwest Florida Reg	22:58 Louisville Standiford Field	7h 28m layover 2h 5m - Newark	United Airlines	UA2477 UA3609
from $202 Find flight	14:30 Fort Myers Southwest Florida Reg	22:24 Louisville Standiford Field	7h 54m layover 2h 59m - Chicago	United Airlines	UA1967 UA3551
from $204 Find flight	12:28 Fort Myers Southwest Florida Reg	20:28 Louisville Standiford Field	8h 0m layover 3h 12m - Chicago	United Airlines	UA2494 UA3598
from $204 Find flight	09:15 Fort Myers Southwest Florida Reg	17:16 Louisville Standiford Field	8h 1m layover 3h 15m - Chicago	United Airlines	UA1811 UA4529
from $206 Find flight	19:20 Fort Myers Southwest Florida Reg	13:37+1 день Louisville Standiford Field	18h 17m layover 14h 11m - Detroit	Spirit Airlines	NK1199 NK1255
from $205 Find flight	19:20 Fort Myers Southwest Florida Reg	14:46+1 день Louisville Standiford Field	19h 26m layover 7h 46m - Detroit 5h 32m - Myrtle Beach	Spirit Airlines	NK1199 NK1002 G41254
from $208 Find flight	11:25 Fort Myers Southwest Florida Reg	15:16+1 день Louisville Standiford Field	27h 51m layover 18h 12m - Minneapolis 2h 12m - Atlanta	Sun Country Airlines	SY384 SY355 NK1858
from $208 Find flight	06:00 Fort Myers Southwest Florida Reg	15:16+1 день Louisville Standiford Field	33h 16m layover 23h 37m - Minneapolis 2h 12m - Atlanta	Sun Country Airlines	SY390 SY355 NK1858
from $210 Find flight	07:00 Fort Myers Southwest Florida Reg	20:28 Louisville Standiford Field	13h 28m layover 3h 25m - Newark 3h 0m - Chicago	United Airlines	UA2468 UA2053 UA3598
from $219 Find flight	11:25 Fort Myers Southwest Florida Reg	13:37+1 день Louisville Standiford Field	26h 12m layover 17h 30m - Minneapolis 2h 12m - Detroit	Sun Country Airlines	SY384 SY1907 NK1255

Show all tickets

*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on July 12, 2025

Flight Schedule Fort Myers (Florida) to Louisville (Kentucky)

Full flight schedule will help you in detecting at what time planes fly from Fort Myers to Louisville. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
17:35 — 20:04	17:35 — 20:04 MX752 Mexicana Fort Myers — Louisville	2h 29m	Find flight from$54
06:00 — 08:55 +1 day	06:00 — 08:35 SY390 Sun Country Airlines Fort Myers — Minneapolis 21h 31m stop 06:06 — 08:55 SY1791 Sun Country Airlines Minneapolis — Louisville	26h 55m including layover	Find flight from$175
07:00 — 13:33	07:00 — 08:40 UA1809 United Airlines Fort Myers — Houston 1h 28m stop 10:08 — 13:33 UA6150 United Airlines Houston — Louisville	6h 33m including layover	Find flight from$202
07:05 — 15:19	07:05 — 09:06 MX744 Mexicana Fort Myers — Raleigh 4h 40m stop 13:46 — 15:19 MX330 Mexicana Raleigh — Louisville	8h 14m including layover	Find flight from$119
09:15 — 17:16	09:15 — 11:30 UA1811 United Airlines Fort Myers — Chicago 3h 15m stop 14:45 — 17:16 UA4529 United Airlines Chicago — Louisville	8h 1m including layover	Find flight from$204
09:15 — 17:16	09:15 — 11:30 UA752 United Airlines Fort Myers — Chicago 3h 15m stop 14:45 — 17:16 UA4529 United Airlines Chicago — Louisville	8h 1m including layover	Find flight from$223
11:25 — 08:55 +1 day	12:48 — 15:24 SY384 Sun Country Airlines Fort Myers — Minneapolis 16h 6m stop 10:24 — 13:12 SY1791 Sun Country Airlines Minneapolis — Louisville	21h 30m including layover	Find flight from$175
12:04 — 19:41	12:04 — 14:32 UA2054 United Airlines Fort Myers — Washington D.C. 3h 18m stop 17:50 — 19:41 UA6242 United Airlines Washington D.C. — Louisville	7h 37m including layover	Find flight from$224
12:28 — 20:28	12:28 — 14:43 UA2494 United Airlines Fort Myers — Chicago 3h 12m stop 17:55 — 20:28 UA3598 United Airlines Chicago — Louisville	8h including layover	Find flight from$204
14:30 — 20:33	14:30 — 16:45 UA1967 United Airlines Fort Myers — Chicago 1h 15m stop 18:00 — 20:33 UA3598 United Airlines Chicago — Louisville	6h 3m including layover	Find flight from$202
14:30 — 22:24	14:30 — 16:45 UA1967 United Airlines Fort Myers — Chicago 2h 59m stop 19:44 — 22:24 UA3551 United Airlines Chicago — Louisville	7h 54m including layover	Find flight from$202
15:30 — 22:58	15:30 — 18:25 UA2477 United Airlines Fort Myers — Newark 2h 5m stop 20:30 — 22:58 UA3609 United Airlines Newark — Louisville	7h 28m including layover	Find flight from$202
16:36 — 22:14	16:36 — 18:55 UA2211 United Airlines Fort Myers — Chicago 45m stop 19:40 — 22:14 UA3551 United Airlines Chicago — Louisville	5h 38m including layover	Find flight from$224
16:39 — 22:24	16:39 — 18:54 UA2738 United Airlines Fort Myers — Chicago 50m stop 19:44 — 22:24 UA3551 United Airlines Chicago — Louisville	5h 45m including layover	Find flight from$222
19:20 — 13:37 +1 day	19:20 — 22:14 NK1199 Spirit Airlines Fort Myers — Detroit 14h 11m stop 12:25 — 13:37 NK1255 Spirit Airlines Detroit — Louisville	18h 17m including layover	Find flight from$206
06:00 — 15:16 +1 day	06:00 — 08:35 SY390 Sun Country Airlines Fort Myers — Minneapolis 23h 37m stop 08:12 — 11:42 SY355 Sun Country Airlines Minneapolis — Atlanta 2h 12m stop 13:54 — 15:16 NK1858 Spirit Airlines Atlanta — Louisville	33h 16m including layover	Find flight from$208
08:00 — 20:32	08:00 — 09:54 MX756 Mexicana Fort Myers — Greenville 5h 25m stop 15:19 — 16:43 G42933 Allegiant Air Greenville — Sanford 1h 47m stop 18:30 — 20:32 G42893 Allegiant Air Sanford — Louisville	12h 32m including layover	Find flight from$252
11:25 — 15:16 +1 day	11:25 — 14:00 SY384 Sun Country Airlines Fort Myers — Minneapolis 18h 12m stop 08:12 — 11:42 SY355 Sun Country Airlines Minneapolis — Atlanta 2h 12m stop 13:54 — 15:16 NK1858 Spirit Airlines Atlanta — Louisville	27h 51m including layover	Find flight from$208
13:37 — 22:14	13:37 — 16:13 UA1753 United Airlines Fort Myers — Cleveland 1h 47m stop 18:00 — 18:35 UA1673 United Airlines Cleveland — Chicago 1h 5m stop 19:40 — 22:14 UA3551 United Airlines Chicago — Louisville	8h 37m including layover	Find flight from$229
13:45 — 22:58	13:37 — 16:13 UA1753 United Airlines Fort Myers — Cleveland 59m stop 17:27 — 19:12 UA3633 United Airlines Cleveland — Newark 1h 24m stop 20:29 — 22:58 UA3609 United Airlines Newark — Louisville	9h 13m including layover	Find flight from$229
19:20 — 14:46 +1 day	19:20 — 22:14 NK1199 Spirit Airlines Fort Myers — Detroit 7h 46m stop 06:00 — 07:39 NK1002 Spirit Airlines Detroit — Myrtle Beach 5h 32m stop 13:11 — 14:46 G41254 Allegiant Air Myrtle Beach — Louisville	19h 26m including layover	Find flight from$205
21:57 — 19:07 +1 day	21:57 — 00:07 NK1872 Spirit Airlines Fort Myers — Chicago 4h 58m stop 05:05 — 09:12 NK1 Spirit Airlines Chicago — Miami 7h 28m stop 16:40 — 19:07 NK1043 Spirit Airlines Miami — Louisville	21h 10m including layover	Find flight from$222

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on July 12, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Fort Myers to Louisville depends on and how to choose the most interesting flight option for you.

Distance between Fort Myers and Louisville is 1347 miles. Time difference between the cities is 0h. Airplanes depart 06:00 to 21:57 from 2 Fort Myers airports and arrive 06:00 to 21:57 to 3 Louisville airports. Average flight time is 2h 29m.

The fastest flight 2h 29m
Average flight time 2h 29m
The earliest flight 06:00
The latest flight 21:57
Distance 837 ml

The cheapest months to travel to Louisville are august (from 54 $), july (from 65 $), october (from 202 $).

The most expensive months are september (from 223 $), october (from 202 $), july (from 65 $).

What is the lowest airfare Fort Myers to Louisville?

The cheapest plane ticket found by our users is $54. This airfare is for economy class on one-way MX752 flight by Mexicana for August 7, 2025 which leaves Southwest Florida Reg in Fort Myers at 17:35 am and arrives at Louisville Standiford Field at 20:04.

Economy class

$54

Find

Business class

Find

First class

Find

Popular Airlines on the Route

The flight Fort Myers — Louisville is served by 5 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Alaska Airlines - 10 departures per week at the price of from $ 6616 . And the most expensive tickets are offered by Alaska Airlines airline - from $ 7040.

Direct flights

There are 1 nonstop flights on the route. The fastest direct flight is MX752 by Mexicana takes 2h 29m and the cheapest is MX752 by Mexicana for $54.

MX - Mexicana

from $54

Find

See more direct flights

Connecting Flights

There are 228 flights with layovers on the route. The fastest connecting flight is UA2211 by United Airlines takes 5h 38m and the cheapest is MX752 by Mexicana for $119.

AS - Alaska Airlines

from $6616

Find
SY - Sun Country Airlines

from $175

Find
MX - Mexicana

from $119

Find
UA - United Airlines

from $202

Find
NK - Spirit Airlines

from $205

Find

See more connecting flights

Airports

You can fly from Fort Myers to Louisville from 2 airports (Southwest Florida Reg, Page Field).

Fort Myers airports

Southwest Florida Reg-RSW

from $54
Find
Page Field-FMY

Find

Louisville airports

Standiford Field-SDF

Find
Intercontinental-LJC

Find
Bowman Field-LOU

Find

Airplanes

There are flights to Louisville from Fort Myers by 5 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Fort Myers

You may also consider searching for discounted plane tickets to some other popular places from Fort Myers within United States.

Fort Myers — Boston

from $77

Find
Fort Myers — New York

from $71

Find
Fort Myers — Key West

from $75

Find
Fort Myers — Orlando

from $75

Find
Fort Myers — Denver

from $61

Find
Fort Myers — Cleveland

from $65

Find
Fort Myers — Nashville

from $65

Find
Fort Myers — Chicago

from $53

Find
Fort Myers — Las Vegas

from $70

Find
Fort Myers — Dallas

from $70

Find

Top International Destinations from Fort Myers

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

Fort Myers — Toronto

from $58

Find
Fort Myers — Cancun

from $68

Find
Fort Myers — Albany

from $62

Find

How to book a plane ticket yourself?

Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
To find a plane ticket, please select dates.