Cheap Flights from Brussels to San Francisco, CA from $319

On Cheapflightsplus.com you will find 1000 connecting flights from Brussels to San Francisco. You can compare airfare deals from 35 airlines and multiple travel sites from $319, book and save on cheap plane tickets and last minute offers. Also check out BRU-SFO flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Brussels to San Francisco depends on and how to choose the most interesting flight option for you.

Distance between Brussels and San Francisco is 8893 miles. Time difference between the cities is 9h. Airplanes depart 05:55 to 22:25 from 2 Brussels airports and arrive 05:55 to 22:25 to 3 San Francisco airports. Average flight time is 25h.

  • The fastest flight 12h 45m
  • Average flight time 25h
  • The earliest flight 05:55
  • The latest flight 22:25
  • Distance 5526 ml

The cheapest months to travel to San Francisco are august (from 319 $), october (from 361 $), september (from 428 $).

The most expensive months are november (from 1 500 $), december (from 975 $), january (from 955 $).

What is the lowest airfare Brussels to San Francisco?

The cheapest plane ticket found by our users is $319. This airfare is for economy class on one-way VY8987 flight by Vueling for August 27, 2025 which leaves Brussels National in Brussels at 15:10 am and arrives at San Francisco San Francisco at 17:25.

Economy class
$319
Find
Business class
?
Find
First class
?
Find

Flight Schedule Brussels to San Francisco (California)

05:55 — 13:35
16h 40m flight time
Find flight
from$481
05:55 — 07:50 Brussels — Lisbon
TP647 TAP Portugal
1h 10m stop
13:00 — 17:35 Lisbon — San Francisco
TP237 TAP Portugal
09:00 — 18:10
18h 10m flight time
Find flight
from$487
08:30 — 10:35 Brussels — Barcelona
FR2917 Ryanair
3h stop
14:05 — 18:10 Barcelona — San Francisco
AY5397 Finnair
10:55 — 17:25
15h 30m flight time
Find flight
from$445
10:40 — 10:55 Brussels — London
BA393 British Airways
3h stop
14:05 — 17:15 London — San Francisco
BA287 British Airways
15:10 — 17:25+1day
35h 15m flight time
Find flight
from$319
15:10 — 17:15 Brussels — Barcelona
VY8987 Vueling
20h 5m stop
14:05 — 18:10 Barcelona — San Francisco
VY9791 Vueling
15:10 — 18:10+1day
36h flight time
Find flight
from$476
15:10 — 17:15 Brussels — Barcelona
VY8987 Vueling
20h 50m stop
14:05 — 18:10 Barcelona — San Francisco
AY5397 Finnair
15:55 — 14:30+1day
31h 35m flight time
Find flight
from$481
15:55 — 17:50 Brussels — Lisbon
TP643 TAP Portugal
16h 5m stop
09:55 — 14:30 Lisbon — San Francisco
TP237 TAP Portugal
16:30 — 18:10+1day
34h 40m flight time
Find flight
from$466
16:30 — 18:35 Brussels — Barcelona
VY8989 Vueling
19h 30m stop
14:05 — 18:10 Barcelona — San Francisco
AY5397 Finnair
18:10 — 17:25+1day
32h 15m flight time
Find flight
from$328
18:05 — 20:15 Brussels — Barcelona
VY8983 Vueling
17h stop
14:05 — 18:10 Barcelona — San Francisco
VY9791 Vueling
18:10 — 17:25+1day
32h 15m flight time
Find flight
from$451
18:05 — 20:15 Brussels — Barcelona
VY8983 Vueling
17h stop
14:05 — 18:10 Barcelona — San Francisco
AY5397 Finnair
18:30 — 17:25+1day
31h 55m flight time
Find flight
from$411
18:30 — 20:30 Brussels — Barcelona
SN3705 Brussels Airlines
16h 50m stop
14:05 — 18:10 Barcelona — San Francisco
VY9791 Vueling
20:35 — 18:10+1day
30h 35m flight time
Find flight
from$458
20:35 — 22:35 Brussels — Barcelona
FR3808 Ryanair
15h 30m stop
14:05 — 18:10 Barcelona — San Francisco
AY5397 Finnair
20:55 — 14:30+1day
26h 35m flight time
Find flight
from$481
20:55 — 22:50 Brussels — Lisbon
TP645 TAP Portugal
11h 5m stop
09:55 — 14:30 Lisbon — San Francisco
TP237 TAP Portugal
22:05 — 13:50+1day
24h 45m flight time
Find flight
from$445
22:05 — 22:15 Brussels — London
BA399 British Airways
12h 30m stop
10:45 — 13:50 London — San Francisco
BA285 British Airways
22:15 — 17:25+1day
28h 10m flight time
Find flight
from$319
22:15 — 00:25 Brussels — Barcelona
VY8985 Vueling
12h 55m stop
14:05 — 18:10 Barcelona — San Francisco
VY9791 Vueling
22:15 — 17:25+1day
28h 10m flight time
Find flight
from$438
22:15 — 00:25 Brussels — Barcelona
VY8985 Vueling
12h 55m stop
14:05 — 18:10 Barcelona — San Francisco
AY5397 Finnair
Full flight schedule will help you in detecting at what time planes fly from Brussels to San Francisco. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on October 26, 2025.

Popular Airlines on the Route

The flight Brussels — San Francisco is served by 35 regular airlines and 7 low-cost airlines. Most of the flights on this route are operated by LOT - 14 departures per week at the price of from $ 893 . And the most expensive tickets are offered by Lufthansa airline - from $ 1596.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 1000 flights with layovers on the route. The fastest connecting flight is KL1702 by KLM takes 12h 45m and the cheapest is VY8987 by Vueling for $319.

  • VY - Vueling
    from $319
    Find
  • FI - Icelandair
    from $635
    Find
  • LO - LOT
    from $893
    Find
  • FR - Ryanair
    from $458
    Find
  • LX - SWISS International Air Lines
    from $558
    Find
  • UA - United Airlines
    from $1562
    Find
  • A3 - Aegean Airlines
    from $930
    Find
  • DY - Norwegian
    from $851
    Find
  • SK - SAS
    from $444
    Find
  • OG - Air Onix
    from $505
    Find
  • IB - Iberia
    from $541
    Find
  • SN - Brussels Airlines
    from $361
    Find
See more connecting flights

Airports

You can fly from Brussels to San Francisco from 2 airports (Brussels National, Charleroi).

Brussels airports

  • Brussels National-BRU
    from $319
    Find
  • Charleroi-CRL
    from $458
    Find

San Francisco airports

  • San Francisco-SFO
    Find
  • Embarkadero-EMB
    Find
  • China Basin Heliport-JCC
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back