American Airlines Detroit to Panama City Flights

Cheapflightsplus.com will find cheap American Airlines flights from Detroit to Panama City. Compare airline ticket prices and book air tickets starting from $95 from trusted online travel agencies, web sites and directly from airlines. Check flights schedule of American Airlines, arrivals and departure details below.

Find Cheap Airfare Detroit (MI) — Panama City by American Airlines

To find cheap tickets choose a day of your departure with attractive price on the graph below and click «Find flights». For round trip flights please click «Check prices for return flight». The cheapest airfare is in may: one-way - $95, two-way – $163.
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Below is a detailed 2024 flight schedule for today, tomorrow and all other days. It may vary depending on season and a day of the week of your desired trip. We recommend booking your itinerary at least 2 weeks prior your travel to get the best price and availability by the airline.
Departure Arrival Flight Details Flight Time Price
10:56 am — 0:58 am
+1 day
10:56 am — 12:28 pm AA5428 American Airlines
Detroit — Philadelphia
2h 52m stop
3:20 pm — 6:10 pm NK1811 Spirit Airlines
Philadelphia — Miami
4h 55m stop
11:05 pm — 0:58 am NK907 Spirit Airlines
Miami — Panama City
15h 2m
including layover
Find flight
from$139
10:59 am — 8:45 pm
10:59 am — 11:12 am AA3149 American Airlines
Detroit — Chicago
48m stop
12:00 pm — 4:04 pm AA219 American Airlines
Chicago — Miami
1h 31m stop
5:35 pm — 8:45 pm AA959 American Airlines
Miami — Panama City
9h 46m
including layover
Find flight
from$194
11:01 am — 2:11 am
+1 day
11:01 am — 12:43 pm AA4443 American Airlines
Detroit — Philadelphia
2h 53m stop
3:36 pm — 6:33 pm AA1870 American Airlines
Philadelphia — Miami
4h 35m stop
11:08 pm — 2:11 am NK907 Spirit Airlines
Miami — Panama City
15h 10m
including layover
Find flight
from$150
11:48 am — 7:45 pm
11:48 am — 1:37 pm AA1244 American Airlines
Detroit — Charlotte
49m stop
2:26 pm — 4:35 pm AA1698 American Airlines
Charlotte — Miami
1h stop
5:35 pm — 7:45 pm AA959 American Airlines
Miami — Panama City
8h 57m
including layover
Find flight
from$194
1:28 pm — 0:57 am
+1 day
1:28 pm — 3:15 pm AA637 American Airlines
Detroit — Charlotte
2h 54m stop
6:09 pm — 8:16 pm AA469 American Airlines
Charlotte — Miami
2h 44m stop
11:00 pm — 0:57 am NK907 Spirit Airlines
Miami — Panama City
12h 29m
including layover
Find flight
from$200
1:44 pm — 12:34 pm
+1 day
1:44 pm — 2:14 pm AA3084 American Airlines
Detroit — Chicago
4h 16m stop
6:30 pm — 10:40 pm AA1277 American Airlines
Chicago — Miami
11h 54m stop
10:34 am — 12:34 pm AA2513 American Airlines
Miami — Panama City
23h 50m
including layover
Find flight
from$467
2:45 pm — 1:03 am
+1 day
2:45 pm — 4:34 pm AA6207 American Airlines
Detroit — Philadelphia
3h 11m stop
7:45 pm — 10:38 pm NK1009 Spirit Airlines
Philadelphia — Miami
32m stop
11:10 pm — 1:03 am NK907 Spirit Airlines
Miami — Panama City
11h 18m
including layover
Find flight
from$95
2:45 pm — 2:11 am
+1 day
2:45 pm — 4:34 pm AA6071 American Airlines
Detroit — Philadelphia
3h 11m stop
7:45 pm — 10:38 pm NK1009 Spirit Airlines
Philadelphia — Miami
30m stop
11:08 pm — 2:11 am NK907 Spirit Airlines
Miami — Panama City
11h 26m
including layover
Find flight
from$96
3:27 pm — 12:34 pm
+1 day
3:27 pm — 5:29 pm AA2559 American Airlines
Detroit — Dallas
1h 21m stop
6:50 pm — 10:50 pm AA2206 American Airlines
Dallas — Miami
11h 44m stop
10:34 am — 12:34 pm AA2513 American Airlines
Miami — Panama City
22h 7m
including layover
Find flight
from$463
3:27 pm — 2:13 pm
+1 day
3:27 pm — 5:29 pm AA2559 American Airlines
Detroit — Dallas
3h 21m stop
8:50 pm — 0:39 am AA2720 American Airlines
Dallas — Miami
11h 32m stop
12:11 pm — 2:13 pm AA1532 American Airlines
Miami — Panama City
23h 46m
including layover
Find flight
from$463
4:40 pm — 12:34 pm
+1 day
4:40 pm — 5:13 pm AA3076 American Airlines
Detroit — Chicago
1h 17m stop
6:30 pm — 10:40 pm AA1277 American Airlines
Chicago — Miami
11h 54m stop
10:34 am — 12:34 pm AA2513 American Airlines
Miami — Panama City
20h 54m
including layover
Find flight
from$463
5:50 pm — 1:03 am
+2 days
5:50 pm — 7:30 pm AA1927 American Airlines
Detroit — Philadelphia
24h 15m stop
7:45 pm — 10:38 pm NK1009 Spirit Airlines
Philadelphia — Miami
32m stop
11:10 pm — 1:03 am NK907 Spirit Airlines
Miami — Panama City
32h 13m
including layover
Find flight
from$95
5:50 pm — 1:03 am
+2 days
5:50 pm — 7:30 pm AA1261 American Airlines
Detroit — Philadelphia
24h 15m stop
7:45 pm — 10:38 pm NK1009 Spirit Airlines
Philadelphia — Miami
32m stop
11:10 pm — 1:03 am NK907 Spirit Airlines
Miami — Panama City
32h 13m
including layover
Find flight
from$98
6:30 am — 2:11 am
+1 day
6:30 am — 8:13 am AA4297 American Airlines
Detroit — New York
4h 52m stop
1:05 pm — 4:18 pm UA2116 United Airlines
New York — Miami
6h 50m stop
11:08 pm — 2:11 am NK907 Spirit Airlines
Miami — Panama City
19h 41m
including layover
Find flight
from$148
6:39 pm — 2:11 am
+2 days
6:39 pm — 8:30 pm AA3577 American Airlines
Detroit — New York
12h 50m stop
9:20 am — 12:33 pm UA745 United Airlines
New York — Miami
10h 35m stop
11:08 pm — 2:11 am NK907 Spirit Airlines
Miami — Panama City
31h 32m
including layover
Find flight
from$150
7:00 am — 0:58 am
+1 day
7:00 am — 7:27 am AA2981 American Airlines
Detroit — Chicago
4h 53m stop
12:20 pm — 4:23 pm NK6 Spirit Airlines
Chicago — Miami
6h 42m stop
11:05 pm — 0:58 am NK907 Spirit Airlines
Miami — Panama City
18h 58m
including layover
Find flight
from$106
7:05 pm — 2:13 pm
+1 day
7:05 pm — 9:00 pm AA5646 American Airlines
Detroit — Charlotte
1h 40m stop
10:40 pm — 0:43 am AA1682 American Airlines
Charlotte — Miami
11h 28m stop
12:11 pm — 2:13 pm AA1532 American Airlines
Miami — Panama City
20h 8m
including layover
Find flight
from$463
8:30 am — 0:58 am
+1 day
8:30 am — 9:10 am AA2998 American Airlines
Detroit — Chicago
3h 10m stop
12:20 pm — 4:23 pm NK6 Spirit Airlines
Chicago — Miami
6h 42m stop
11:05 pm — 0:58 am NK907 Spirit Airlines
Miami — Panama City
17h 28m
including layover
Find flight
from$106
8:43 am — 8:31 pm
8:43 am — 9:15 am AA3093 American Airlines
Detroit — Chicago
2h 45m stop
12:00 pm — 4:04 pm AA335 American Airlines
Chicago — Miami
2h 21m stop
6:25 pm — 8:31 pm AA959 American Airlines
Miami — Panama City
12h 48m
including layover
Find flight
from$521
*Departure and arrival times are local. Last updated on 05/05/2024

Flight Information

There are 87 flights by American Airlines from Detroit to Panama City every week with departures from Detroit City and Willow Run. All flights arrive at Tocumen and Paitilla.

Departures start from 10:08 am to 8:43 am. Nonstop flight is 6h 53m. The time difference between Detroit and Panama City is 0h.

  • The fastest flight 6h 53m
  • Average flight time 14h 6m
  • The earliest flight 10:08 am
  • The latest flight 8:43 am
  • Distance 2310 ml

The cheapest flight by American Airlines that our users were able to find is $95. This airfare is economy class on one-way AA6207 flight for October 7, 2020 leaving All airports in Detroit at 2:45 pm, it includes all taxes and additional fees.

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Other Popular Airlines on the Route

Besides American Airlines there are other 9 airline carriers between Detroit and Panama City. Please review schedules and prices from the most popular airlines to find the best airfare deals from Detroit to Panama City.

Nonstop flights

There’re no direct flights on this route. Try flights with stops.

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Connecting Flights

List of flights with layovers (1 and more stops):

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How to book an air ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected airfare.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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