Spirit Airlines Detroit to Panama City Flights

Cheapflightsplus.com will find cheap Spirit Airlines flights from Detroit to Panama City. Compare airline ticket prices and book air tickets starting from $201 from trusted online travel agencies, web sites and directly from airlines. Check flights schedule of Spirit Airlines, arrivals and departure details below.

Find Cheap Airfare Detroit (MI) — Panama City by Spirit Airlines

To find cheap tickets choose a day of your departure with attractive price on the graph below and click «Find flights». For round trip flights please click «Check prices for return flight». The cheapest airfare is in january: one-way - $201, two-way – $345.
Direct flights
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Below is a detailed 2025 flight schedule for today, tomorrow and all other days. It may vary depending on season and a day of the week of your desired trip. We recommend booking your itinerary at least 2 weeks prior your travel to get the best price and availability by the airline.
Departure Arrival Flight Details Flight Time Price
10:14 am — 10:25 am
+1 day
10:14 am — 12:00 pm NK381 Spirit Airlines
Detroit — New York
14h 35m stop
2:35 am — 6:30 am AV571 Avianca
New York — San Salvador
1h stop
7:30 am — 10:25 am AV323 Avianca
San Salvador — Panama City
24h 11m
including layover
Find flight
from$273
10:15 am — 10:25 am
+1 day
10:15 am — 12:00 pm NK289 Spirit Airlines
Detroit — New York
14h 35m stop
2:35 am — 6:30 am AV571 Avianca
New York — San Salvador
1h stop
7:30 am — 10:25 am AV323 Avianca
San Salvador — Panama City
24h 10m
including layover
Find flight
from$201
11:33 am — 4:13 pm
+1 day
11:33 am — 1:15 pm NK820 Spirit Airlines
Detroit — New Orleans
4h 33m stop
5:48 pm — 8:49 pm NK343 Spirit Airlines
New Orleans — Miami
16h 16m stop
1:05 pm — 4:13 pm CM481 Compania Panamena de Aviacion
Miami — Panama City
28h 40m
including layover
Find flight
from$288
11:33 am — 8:04 am
+1 day
11:33 am — 1:15 pm NK820 Spirit Airlines
Detroit — New Orleans
4h 33m stop
5:48 pm — 8:49 pm NK343 Spirit Airlines
New Orleans — Miami
8h 7m stop
4:56 am — 8:04 am CM173 Compania Panamena de Aviacion
Miami — Panama City
20h 31m
including layover
Find flight
from$288
1:32 pm — 10:25 am
+1 day
1:32 pm — 3:18 pm NK1022 Spirit Airlines
Detroit — New York
11h 17m stop
2:35 am — 6:30 am AV571 Avianca
New York — San Salvador
1h stop
7:30 am — 10:25 am AV323 Avianca
San Salvador — Panama City
20h 53m
including layover
Find flight
from$273
1:47 pm — 8:04 am
+1 day
1:47 pm — 3:26 pm NK1013 Spirit Airlines
Detroit — Philadelphia
1h 49m stop
5:15 pm — 8:18 pm NK3149 Spirit Airlines
Philadelphia — Miami
8h 38m stop
5:02 am — 8:12 am CM173 Compania Panamena de Aviacion
Miami — Panama City
18h 17m
including layover
Find flight
from$282
3:14 pm — 2:45 pm
+1 day
3:14 pm — 4:58 pm NK172 Spirit Airlines
Detroit — New York
12h 47m stop
5:45 am — 9:50 am AV569 Avianca
New York — San Salvador
2h stop
11:50 am — 2:45 pm AV317 Avianca
San Salvador — Panama City
23h 31m
including layover
Find flight
from$266
3:14 pm — 10:25 am
+1 day
3:14 pm — 4:58 pm NK172 Spirit Airlines
Detroit — New York
9h 37m stop
2:35 am — 6:30 am AV571 Avianca
New York — San Salvador
1h stop
7:30 am — 10:25 am AV323 Avianca
San Salvador — Panama City
19h 11m
including layover
Find flight
from$273
4:30 pm — 10:25 am
+1 day
4:30 pm — 7:46 pm NK366 Spirit Airlines
Detroit — Miami
3h 14m stop
11:00 pm — 0:51 am NK1031 Spirit Airlines
Miami — San Salvador
6h 39m stop
7:30 am — 10:25 am AV323 Avianca
San Salvador — Panama City
17h 55m
including layover
Find flight
from$284
4:40 pm — 7:15 pm
+1 day
4:40 pm — 7:30 pm NK2992 Spirit Airlines
Detroit — Miami
17h 55m stop
1:25 pm — 4:45 pm AV139 Avianca
Miami — Medellin
1h 15m stop
6:00 pm — 7:15 pm AV316 Avianca
Medellin — Panama City
26h 35m
including layover
Find flight
from$358
6:15 am — 10:25 am
+1 day
6:15 am — 8:00 am NK2963 Spirit Airlines
Detroit — New York
18h 35m stop
2:35 am — 6:30 am AV571 Avianca
New York — San Salvador
1h stop
7:30 am — 10:25 am AV323 Avianca
San Salvador — Panama City
28h 10m
including layover
Find flight
from$201
6:16 pm — 10:25 am
+1 day
6:16 pm — 8:00 pm NK229 Spirit Airlines
Detroit — New York
6h 35m stop
2:35 am — 6:30 am AV571 Avianca
New York — San Salvador
1h stop
7:30 am — 10:25 am AV323 Avianca
San Salvador — Panama City
16h 9m
including layover
Find flight
from$201
7:15 am — 8:04 am
+1 day
7:15 am — 9:00 am NK3393 Spirit Airlines
Detroit — New York
55m stop
9:55 am — 1:17 pm NK1440 Spirit Airlines
New York — Miami
15h 39m stop
4:56 am — 8:04 am CM173 Compania Panamena de Aviacion
Miami — Panama City
24h 49m
including layover
Find flight
from$307
7:30 pm — 4:13 pm
+1 day
7:30 pm — 9:32 pm NK1020 Spirit Airlines
Detroit — Dallas
7h 33m stop
5:05 am — 8:50 am NK1860 Spirit Airlines
Dallas — Miami
4h 15m stop
1:05 pm — 4:13 pm CM481 Compania Panamena de Aviacion
Miami — Panama City
20h 43m
including layover
Find flight
from$403
8:10 am — 7:15 pm
8:10 am — 11:00 am NK1692 Spirit Airlines
Detroit — Miami
2h 25m stop
1:25 pm — 4:45 pm AV139 Avianca
Miami — Medellin
1h 15m stop
6:00 pm — 7:15 pm AV316 Avianca
Medellin — Panama City
11h 5m
including layover
Find flight
from$268
8:20 pm — 10:25 am
+2 days
7:15 pm — 9:30 pm NK3788 Spirit Airlines
Detroit — Houston
14h 42m stop
1:00 pm — 4:00 pm AV367 Avianca
Houston — San Salvador
15h 30m stop
7:30 am — 10:25 am AV323 Avianca
San Salvador — Panama City
38h 5m
including layover
Find flight
from$251
9:03 am — 10:25 am
+1 day
9:03 am — 11:27 am NK227 Spirit Airlines
Detroit — Houston
5h 3m stop
4:30 pm — 7:25 pm AV425 Avianca
Houston — San Salvador
12h 5m stop
7:30 am — 10:25 am AV323 Avianca
San Salvador — Panama City
25h 22m
including layover
Find flight
from$285
9:06 pm — 8:10 am
+2 days
9:06 pm — 11:21 pm NK3788 Spirit Airlines
Detroit — Houston
14h 59m stop
2:20 pm — 5:15 pm NK255 Spirit Airlines
Houston — San Salvador
11h 47m stop
5:02 am — 8:10 am CM879 Compania Panamena de Aviacion
San Salvador — Panama City
35h 4m
including layover
Find flight
from$499
*Departure and arrival times are local. Last updated on 12/27/2024

Flight Information

There are 82 flights by Spirit Airlines from Detroit to Panama City every week with departures from Detroit City and Willow Run. All flights arrive at Tocumen and Paitilla.

Departures start from 10:14 am to 9:17 am. Nonstop flight is 8h 3m. The time difference between Detroit and Panama City is 0h.

  • The fastest flight 8h 3m
  • Average flight time 19h
  • The earliest flight 10:14 am
  • The latest flight 9:17 am
  • Distance 2310 ml

The cheapest months for traveling to Panama City are january (from 201 $), february (from 232 $), november (from 297 $).

The most expensive and popular months are december (from 317 $), november (from 297 $), february (from 232 $).

The cheapest flight by Spirit Airlines that our users were able to find is $201. This airfare is economy class on one-way NK229 flight for January 22, 2025 leaving All airports in Detroit at 6:16 pm, it includes all taxes and additional fees.

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Other Popular Airlines on the Route

Besides Spirit Airlines there are other 8 airline carriers between Detroit and Panama City. Please review schedules and prices from the most popular airlines to find the best airfare deals from Detroit to Panama City.

Nonstop flights

There’re no direct flights on this route. Try flights with stops.

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Connecting Flights

List of flights with layovers (1 and more stops):

  • from $395
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  • from $364
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  • from $611
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  • F9 - Frontier Airlines
    from $224
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  • UX - Air Europa
    from $4625
    Find
  • SY - Sun Country Airlines
    from $924
    Find
  • TK - Turkish Airlines
    from $1318
    Find
  • WS - WestJet
    from $1277
    Find
See more connecting flights

How to book an air ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected airfare.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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