American Airlines Des Moines to San Francisco Flights

Cheapflightsplus.com will find cheap American Airlines flights from Des Moines to San Francisco. Compare airline ticket prices and book air tickets starting from $161 from trusted online travel agencies, web sites and directly from airlines. Check flights schedule of American Airlines, arrivals and departure details below.

Find Cheap Airfare Des Moines (IA) — San Francisco (CA) by American Airlines

To find cheap tickets choose a day of your departure with attractive price on the graph below and click «Find flights». For round trip flights please click «Check prices for return flight». The cheapest airfare is in may: one-way - $161, two-way – $276.
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Below is a detailed 2024 flight schedule for today, tomorrow and all other days. It may vary depending on season and a day of the week of your desired trip. We recommend booking your itinerary at least 2 weeks prior your travel to get the best price and availability by the airline.
Departure Arrival Flight Details Flight Time Price
11:38 am — 5:39 pm
11:38 am — 1:04 pm AA3064 American Airlines
Des Moines — Chicago
2h 1m stop
3:05 pm — 5:39 pm AA2639 American Airlines
Chicago — San Francisco
8h 1m
including layover
Find flight
from$161
12:20 pm — 5:38 pm
12:20 pm — 1:42 pm AA3407 American Airlines
Des Moines — Chicago
1h 18m stop
3:00 pm — 5:38 pm AA2639 American Airlines
Chicago — San Francisco
7h 18m
including layover
Find flight
from$195
12:20 pm — 7:47 pm
12:20 pm — 1:42 pm AA3407 American Airlines
Des Moines — Chicago
3h 18m stop
5:00 pm — 7:47 pm AA2798 American Airlines
Chicago — San Francisco
9h 27m
including layover
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from$212
1:15 pm — 6:40 pm
1:15 pm — 3:16 pm AA1281 American Airlines
Des Moines — Dallas
1h 39m stop
4:55 pm — 6:40 pm AA1175 American Airlines
Dallas — San Francisco
7h 25m
including layover
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from$161
1:15 pm — 8:45 pm
1:15 pm — 3:16 pm AA1281 American Airlines
Des Moines — Dallas
3h 34m stop
6:50 pm — 8:45 pm AA1430 American Airlines
Dallas — San Francisco
9h 30m
including layover
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from$161
2:09 pm — 7:16 pm
2:09 pm — 3:10 pm AA1959 American Airlines
Des Moines — Phoenix
2h 5m stop
5:15 pm — 7:16 pm AA686 American Airlines
Phoenix — San Francisco
7h 7m
including layover
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from$161
2:15 pm — 7:37 pm
2:15 pm — 3:39 pm AA4144 American Airlines
Des Moines — Chicago
1h 21m stop
5:00 pm — 7:37 pm AA2798 American Airlines
Chicago — San Francisco
7h 22m
including layover
Find flight
from$249
3:14 pm — 11:01 pm
3:14 pm — 6:47 pm AA5192 American Airlines
Des Moines — Charlotte
1h 37m stop
8:24 pm — 11:01 pm AA847 American Airlines
Charlotte — San Francisco
9h 47m
including layover
Find flight
from$869
5:15 pm — 10:33 pm
5:15 pm — 7:20 pm AA2388 American Airlines
Des Moines — Dallas
1h 25m stop
8:45 pm — 10:33 pm AA75 American Airlines
Dallas — San Francisco
7h 18m
including layover
Find flight
from$161
5:15 pm — 0:02 am
+1 day
5:15 pm — 7:20 pm AA2388 American Airlines
Des Moines — Dallas
2h 55m stop
10:15 pm — 0:02 am AA446 American Airlines
Dallas — San Francisco
8h 47m
including layover
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from$161
6:08 am — 1:10 pm
6:08 am — 7:35 am AA4206 American Airlines
Des Moines — Chicago
2h 45m stop
10:20 am — 1:10 pm AA2634 American Airlines
Chicago — San Francisco
9h 2m
including layover
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from$195
7:25 am — 2:48 pm
7:25 am — 9:30 am AA2326 American Airlines
Des Moines — Dallas
3h 32m stop
1:02 pm — 2:48 pm AA139 American Airlines
Dallas — San Francisco
9h 23m
including layover
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from$161
7:27 am — 12:27 pm
7:27 am — 9:30 am AA2326 American Airlines
Des Moines — Dallas
1h 10m stop
10:40 am — 12:27 pm AA2248 American Airlines
Dallas — San Francisco
7h
including layover
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from$161
8:01 am — 12:39 pm
8:01 am — 9:11 am AA1795 American Airlines
Des Moines — Phoenix
1h 13m stop
10:24 am — 12:39 pm AA1821 American Airlines
Phoenix — San Francisco
6h 38m
including layover
Find flight
from$212
8:39 am — 2:26 pm
8:39 am — 10:00 am AA4200 American Airlines
Des Moines — Chicago
1h 45m stop
11:45 am — 2:26 pm AA1470 American Airlines
Chicago — San Francisco
7h 47m
including layover
Find flight
from$212
11:38 am — 7:15 pm
11:38 am — 1:04 pm AA3064 American Airlines
Des Moines — Chicago
46m stop
1:50 pm — 3:28 pm AA602 American Airlines
Chicago — Phoenix
1h 47m stop
5:15 pm — 7:15 pm AA686 American Airlines
Phoenix — San Francisco
9h 37m
including layover
Find flight
from$164
6:08 am — 1:56 pm
6:08 am — 7:35 am AA4206 American Airlines
Des Moines — Chicago
1h 30m stop
9:05 am — 11:43 am AA1163 American Airlines
Chicago — Los Angeles
47m stop
12:30 pm — 1:56 pm AA6007 American Airlines
Los Angeles — San Francisco
9h 48m
including layover
Find flight
from$215
*Departure and arrival times are local. Last updated on 05/08/2024

Flight Information

There are 85 flights by American Airlines from Des Moines to San Francisco every week with departures from Des Moines International Airport. All flights arrive at San Francisco, Embarkadero, China Basin Heliport.

Departures start from 11:38 am to 8:39 am. Nonstop flight is 6h 38m. The time difference between Des Moines and San Francisco is 2h.

  • The fastest flight 6h 38m
  • Average flight time 10h 13m
  • The earliest flight 11:38 am
  • The latest flight 8:39 am
  • Distance 1546 ml

The cheapest months for traveling to San Francisco are may (from 223 $).

The cheapest flight by American Airlines that our users were able to find is $161. This airfare is economy class on one-way AA2326 flight for October 4, 2018 leaving Des Moines International Airport in Des Moines at 7:27 am, it includes all taxes and additional fees.

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Other Popular Airlines on the Route

Besides American Airlines there are other 1 airline carriers between Des Moines and San Francisco. Please review schedules and prices from the most popular airlines to find the best airfare deals from Des Moines to San Francisco.

Nonstop flights

There’re no direct flights on this route. Try flights with stops.

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Connecting Flights

List of flights with layovers (1 and more stops):

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How to book an air ticket yourself?

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  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

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