Cheap Flights from San Francisco, CA to Prague from $221

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On Cheapflightsplus.com you will find 1000 connecting flights from San Francisco to Prague. You can compare airfare deals from 19 airlines and multiple travel sites from $221, book and save on cheap plane tickets and last minute offers. Also check out SFO-PRG flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip San Francisco to Prague Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $221 (one-way), $379 (round-trip).

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Best Flights from San Francisco to Prague Today

Take a look at the list of non stop flights and flights with layovers from San Francisco to Prague with the lowest price of $221. Take a look at the list of flights with layovers from San Francisco to Prague from $221. There’re no direct flights. The fastest connecting flight – 14h.

Price	Departure	Arrival	Flight Duration	Airline	Flight
from $221 Find flight	11:38 San Francisco San Francisco	09:00+2 дня Prague Ruzyne	36h 22m layover 3h 27m - Las Vegas 19h 25m - London	Frontier Airlines	F92486 Z0778 W92602
from $263 Find flight	08:35 San Francisco San Francisco	20:10+1 день Prague Ruzyne	26h 35m layover 6h 28m - Las Vegas 6h 40m - London	Frontier Airlines	F94158 Z0778 U28783
from $285 Find flight	22:59 San Francisco San Francisco	21:10+2 дня Prague Ruzyne	37h 11m layover 16h 2m - Las Vegas 7h 35m - London	Frontier Airlines	F93020 Z0778 W92604
from $285 Find flight	22:11 San Francisco San Francisco	21:10+2 дня Prague Ruzyne	37h 59m layover 16h 54m - Las Vegas 7h 35m - London	Frontier Airlines	F94156 Z0778 W92604
from $288 Find flight	22:59 San Francisco San Francisco	21:10+2 дня Prague Ruzyne	37h 11m layover 16h 3m - Las Vegas 7h 35m - London	Frontier Airlines	F91850 Z0778 W92604
from $302 Find flight	21:05 San Francisco San Francisco	09:00+3 дня Prague Ruzyne	50h 55m layover 18h 2m - Las Vegas 19h 25m - London	Frontier Airlines	F94156 Z0778 W92602
from $304 Find flight	22:59 San Francisco San Francisco	20:30+2 дня Prague Ruzyne	36h 31m layover 16h 3m - Las Vegas 6h 55m - London	Frontier Airlines	F91850 Z0778 U22635
from $310 Find flight	22:59 San Francisco San Francisco	09:00+3 дня Prague Ruzyne	49h 1m layover 16h 2m - Las Vegas 19h 25m - London	Frontier Airlines	F93020 Z0778 W92602
from $327 Find flight	22:59 San Francisco San Francisco	18:40+2 дня Prague Ruzyne	34h 41m layover 16h 3m - Las Vegas 5h 10m - London	Frontier Airlines	F91850 Z0778 U28781
from $335 Find flight	22:11 San Francisco San Francisco	20:20+2 дня Prague Ruzyne	37h 9m layover 16h 54m - Las Vegas 6h 50m - London	Frontier Airlines	F94156 Z0778 U26347
from $335 Find flight	18:33 San Francisco San Francisco	20:20+2 дня Prague Ruzyne	40h 47m layover 20h 32m - Las Vegas 6h 50m - London	Frontier Airlines	F93020 Z0778 U26347
from $341 Find flight	21:05 San Francisco San Francisco	10:30+3 дня Prague Ruzyne	52h 25m layover 18h 2m - Las Vegas 21h 0m - London	Frontier Airlines	F94156 Z0778 W95775
from $349 Find flight	22:59 San Francisco San Francisco	09:35+3 дня Prague Ruzyne	49h 36m layover 16h 2m - Las Vegas 20h 5m - London	Frontier Airlines	F93020 Z0778 W95775
from $361 Find flight	19:25 San Francisco San Francisco	08:05+3 дня Prague Ruzyne	51h 40m layover 21h 50m - Zurich 16h 15m - Milan	SWISS International Air Lines	LX39 LX1628 W46331
from $364 Find flight	07:00 San Francisco San Francisco	21:10+1 день Prague Ruzyne	29h 10m layover 8h 7m - Las Vegas 7h 35m - London	Alaska Airlines	AS231 Z0778 W92604
from $367 Find flight	14:10 San Francisco San Francisco	08:05+2 дня Prague Ruzyne	32h 55m layover 1h 40m - Rome 16h 20m - Milan	Alitalia	AZ641 AZ2032 W46331

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*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on May 11, 2025

Flight Schedule San Francisco (California) to Prague

Full flight schedule will help you in detecting at what time planes fly from San Francisco to Prague. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.

Departure	Flight Details	Flight Duration	Price
13:35 — 13:10 +1 day	13:35 — 09:50 UA194 United Airlines San Francisco — Munich 2h 30m stop 12:20 — 13:10 UA9250 United Airlines Munich — Prague	14h 35m including layover	Find flight from$667
13:35 — 16:05 +1 day	13:35 — 09:50 UA194 United Airlines San Francisco — Munich 5h 25m stop 15:15 — 16:05 UA9258 United Airlines Munich — Prague	17h 30m including layover	Find flight from$667
14:10 — 22:20 +1 day	14:10 — 11:20 AZ641 Alitalia San Francisco — Rome 9h stop 20:20 — 22:20 W46065 Aero Services Executive Rome — Prague	23h 10m including layover	Find flight from$588
14:40 — 13:55 +1 day	14:40 — 10:30 LH455 Lufthansa San Francisco — Frankfurt 2h 20m stop 13:20 — 14:25 LH1396 Lufthansa Frankfurt — Prague	14h 15m including layover	Find flight from$616
16:40 — 21:10 +1 day	16:40 — 10:55 VS20 Virgin Atlantic Airways San Francisco — London 7h 15m stop 18:10 — 21:10 W92604 Wizz Air UK London — Prague	19h 30m including layover	Find flight from$565
16:40 — 18:25 +1 day	16:35 — 11:30 TP238 TAP Portugal San Francisco — Lisbon 2h 25m stop 14:00 — 18:25 TP1242 TAP Portugal Lisbon — Prague	16h 45m including layover	Find flight from$572
17:30 — 21:10 +1 day	17:30 — 12:00 IB3625 Iberia San Francisco — London 6h 10m stop 18:10 — 21:10 W92604 Wizz Air UK London — Prague	18h 40m including layover	Find flight from$564
17:30 — 21:10 +1 day	17:30 — 12:00 BA284 British Airways San Francisco — London 6h 10m stop 18:10 — 21:10 W92604 Wizz Air UK London — Prague	18h 40m including layover	Find flight from$568
19:55 — 20:10 +1 day	19:55 — 15:30 BF711 Bluebird Cargo San Francisco — Paris 2h 55m stop 18:30 — 20:15 TO4398 Transavia France Paris — Prague	15h 15m including layover	Find flight from$489
19:55 — 16:45 +2 days	19:55 — 15:30 BF711 Bluebird Cargo San Francisco — Paris 23h 30m stop 15:00 — 16:45 QS1035 SmartWings Paris — Prague	35h 50m including layover	Find flight from$498
20:40 — 09:00 +2 days	20:40 — 15:15 BA286 British Airways San Francisco — London 14h 45m stop 06:00 — 09:00 W92602 Wizz Air UK London — Prague	27h 20m including layover	Find flight from$564
20:50 — 09:00 +2 days	20:40 — 15:15 IB3627 Iberia San Francisco — London 14h 35m stop 06:00 — 09:00 W92602 Wizz Air UK London — Prague	27h 10m including layover	Find flight from$567

Departure	Arrival	Flight Details	Flight Time	Price
		stop stop	including layover	Find flight from$

*Departure and arrival times - local. Updated on May 11, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from San Francisco to Prague depends on and how to choose the most interesting flight option for you.

Distance between San Francisco and Prague is 9376 miles. Time difference between the cities is 9h. Airplanes depart 00:23 to 23:59 from 3 San Francisco airports and arrive 00:23 to 23:59 to 2 Prague airports. Average flight time is 24h 39m.

The fastest flight 14h
Average flight time 24h 39m
The earliest flight 00:23
The latest flight 23:59
Distance 5826 ml

The cheapest months to travel to Prague are november (from 221 $), january (from 288 $), february (from 361 $).

The most expensive months are december (from 426 $), february (from 361 $), january (from 288 $).

What is the lowest airfare San Francisco to Prague?

The cheapest plane ticket found by our users is $221. This airfare is for economy class on one-way F94158 flight by Frontier Airlines for November 17, 2024 which leaves San Francisco in San Francisco at 08:35 am and arrives at Prague Ruzyne at 09:00.

Economy class

$221

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Business class

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First class

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Popular Airlines on the Route

The flight San Francisco — Prague is served by 19 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by Air Canada - 95 departures per week at the price of from $ 443 . And the most expensive tickets are offered by Air Canada airline - from $ 841.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 1000 flights with layovers on the route. The fastest connecting flight is UA926 by United Airlines takes 14h and the cheapest is F94158 by Frontier Airlines for $221.

AC - Air Canada

from $443

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BF - Bluebird Cargo

from $463

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TX - Air Caraibes

from $615

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OS - Austrian Airlines

from $648

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LX - SWISS International Air Lines

from $361

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UA - United Airlines

from $666

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AS - Alaska Airlines

from $364

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F9 - Frontier Airlines

from $221

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TK - Turkish Airlines

from $782

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SK - SAS

from $744

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AY - Finnair

from $754

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AZ - Alitalia

from $367

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See more connecting flights

Airports

You can fly from San Francisco to Prague from 3 airports (San Francisco, Embarkadero, China Basin Heliport).

San Francisco airports

San Francisco-SFO

from $221
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Embarkadero-EMB

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China Basin Heliport-JCC

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Prague airports

Ruzyne-PRG

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Vodochody-VOD

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Airplanes

There are flights to Prague from San Francisco by 19 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from San Francisco

You may also consider searching for discounted plane tickets to some other popular places from San Francisco within United States.

San Francisco — Los Angeles

from $62

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San Francisco — New York

from $70

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San Francisco — Las Vegas

from $57

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San Francisco — San Diego

from $67

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San Francisco — Seattle

from $54

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San Francisco — Chicago

from $69

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San Francisco — Boston

from $59

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San Francisco — Miami

from $61

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San Francisco — Phoenix

from $58

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San Francisco — Washington D.C.

from $66

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Top International Destinations from San Francisco

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

San Francisco — Vancouver

from $56

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San Francisco — London

from $72

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San Francisco — Tokyo

from $73

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San Francisco — Toronto

from $67

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San Francisco — Mumbai

from $63

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San Francisco — Paris

from $58

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San Francisco — Sydney

from $78

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San Francisco — Manila

from $67

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San Francisco — Cancun

from $69

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San Francisco — Singapore

from $56

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How to book a plane ticket yourself?

Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.
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