Cheap Flights from Phoenix, AZ to Panama City from $253

On Cheapflightsplus.com you will find 264 connecting flights from Phoenix to Panama City. You can compare airfare deals from 14 airlines and multiple travel sites from $253, book and save on cheap plane tickets and last minute offers. Also check out PHX-PTY flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Phoenix to Panama City depends on and how to choose the most interesting flight option for you.

Distance between Phoenix and Panama City is 4298 miles. Time difference between the cities is 2h. Airplanes depart 00:20 to 23:59 from 5 Phoenix airports and arrive 00:20 to 23:59 to 2 Panama City airports. Average flight time is 22h 33m.

  • The fastest flight 7h 42m
  • Average flight time 22h 33m
  • The earliest flight 00:20
  • The latest flight 23:59
  • Distance 2671 ml

The cheapest months to travel to Panama City are july (from 253 $), august (from 284 $), february (from 392 $).

The most expensive months are october (from 518 $), september (from 449 $), february (from 392 $).

What is the lowest airfare Phoenix to Panama City?

The cheapest plane ticket found by our users is $253. This airfare is for economy class on one-way F91061 flight by Frontier Airlines for July 6, 2025 which leaves Sky Harbor Intl in Phoenix at 06:05 am and arrives at Panama City Tocumen at 10:25.

Economy class
$253
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Business class
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First class
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Flight Schedule Phoenix (Arizona) to Panama City

06:00 — 18:37
10h 37m flight time
Find flight
from$287
06:00 — 10:38 Phoenix — Houston
UA1318 United Airlines
3h 42m stop
14:20 — 18:37 Houston — Panama City
UA1034 United Airlines
06:05 — 10:25+1day
26h 20m flight time
Find flight
from$253
06:05 — 07:34 Phoenix — Los Angeles
F91061 Frontier Airlines
8h 21m stop
15:55 — 21:55 Los Angeles — San Salvador
AV525 Avianca
9h 35m stop
07:30 — 10:25 San Salvador — Panama City
AV323 Avianca
07:10 — 20:10
11h flight time
Find flight
from$287
07:10 — 09:15 Phoenix — San Francisco
UA246 United Airlines
1h 40m stop
10:55 — 20:10 San Francisco — Panama City
UA1103 United Airlines
07:15 — 20:10
10h 55m flight time
Find flight
from$285
07:15 — 09:19 Phoenix — San Francisco
UA2209 United Airlines
1h 36m stop
10:55 — 20:10 San Francisco — Panama City
UA1103 United Airlines
08:38 — 18:37
7h 59m flight time
Find flight
from$285
08:25 — 13:08 Phoenix — Houston
UA636 United Airlines
1h 4m stop
14:25 — 18:37 Houston — Panama City
UA1034 United Airlines
08:38 — 14:14+1day
27h 36m flight time
Find flight
from$291
08:25 — 13:08 Phoenix — Houston
UA636 United Airlines
20h 38m stop
09:59 — 14:14 Houston — Panama City
UA1916 United Airlines
08:55 — 18:37
7h 42m flight time
Find flight
from$287
08:55 — 13:33 Phoenix — Houston
UA2858 United Airlines
47m stop
14:20 — 18:37 Houston — Panama City
UA1034 United Airlines
11:50 — 20:10+1day
30h 20m flight time
Find flight
from$290
11:50 — 13:49 Phoenix — San Francisco
UA2225 United Airlines
21h 6m stop
10:55 — 20:10 San Francisco — Panama City
UA1103 United Airlines
12:09 — 16:12+1day
26h 3m flight time
Find flight
from$290
11:25 — 15:00 Phoenix — Houston
UA1477 United Airlines
19h 5m stop
11:56 — 17:07 Houston — Panama City
UA1250 United Airlines
16:09 — 16:12+1day
22h 3m flight time
Find flight
from$290
16:09 — 20:50 Phoenix — Houston
UA1885 United Airlines
15h 7m stop
11:57 — 16:12 Houston — Panama City
UA1250 United Airlines
17:27 — 12:35+2days
41h 8m flight time
Find flight
from$283
17:27 — 00:56 Phoenix — Orlando
F91086 Frontier Airlines
8h 26m stop
09:10 — 10:29 Orlando — San Jose
NK1309 Spirit Airlines
23h 39m stop
10:15 — 12:35 San Jose — Panama City
AV643 Avianca
18:16 — 14:14+1day
17h 58m flight time
Find flight
from$284
18:16 — 22:59 Phoenix — Houston
UA2249 United Airlines
11h stop
09:59 — 14:14 Houston — Panama City
UA1916 United Airlines
18:16 — 16:12+1day
19h 56m flight time
Find flight
from$290
18:16 — 22:59 Phoenix — Houston
UA2249 United Airlines
12h 58m stop
11:57 — 16:12 Houston — Panama City
UA1250 United Airlines
18:16 — 18:37+1day
22h 21m flight time
Find flight
from$290
18:16 — 22:59 Phoenix — Houston
UA2249 United Airlines
15h 26m stop
14:25 — 18:37 Houston — Panama City
UA1034 United Airlines
19:37 — 20:10+1day
22h 33m flight time
Find flight
from$290
19:37 — 21:39 Phoenix — San Francisco
UA1190 United Airlines
13h 16m stop
10:55 — 20:10 San Francisco — Panama City
UA1103 United Airlines
Full flight schedule will help you in detecting at what time planes fly from Phoenix to Panama City. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on November 8, 2025.

Popular Airlines on the Route

The flight Phoenix — Panama City is served by 14 regular airlines and 6 low-cost airlines. Most of the flights on this route are operated by Air Canada - 5 departures per week at the price of from $ 540 . And the most expensive tickets are offered by United Airlines airline - from $ 4070.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 264 flights with layovers on the route. The fastest connecting flight is UA2858 by United Airlines takes 7h 42m and the cheapest is F91061 by Frontier Airlines for $253.

  • AC - Air Canada
    from $540
    Find
  • CM - Compania Panamena de Aviacion
    from $415
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  • UA - United Airlines
    from $284
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  • AM - Aeromexico
    from $358
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  • G4 - Allegiant Air
    from $730
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  • AS - Alaska Airlines
    from $449
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  • F9 - Frontier Airlines
    from $253
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  • PD - Porter Airlines
    from $538
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  • AV - Avianca
    from $435
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  • HA - Hawaiian Airlines
    from $347
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  • Y4 - Volaris
    from $304
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  • NK - Spirit Airlines
    from $301
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See more connecting flights

Airports

You can fly from Phoenix to Panama City from 5 airports (Williams Gateway, Sky Harbor Intl, Phoenix-Deer Valley, Luke AFB, Scottsdale Municipal).

Phoenix airports

  • Williams Gateway-AZA
    from $730
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  • Sky Harbor Intl-PHX
    from $253
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  • Phoenix-Deer Valley-DVT
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  • Luke AFB-LUF
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  • Scottsdale Municipal-SCF
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Panama City airports

  • Tocumen-PTY
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  • Paitilla-PAC
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

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