Cheap Flights from Orlando, FL to Santo Domingo from $384

On Cheapflightsplus.com you will find 14 connecting flights from Orlando to Santo Domingo. You can compare airfare deals from 5 airlines and multiple travel sites from $384, book and save on cheap plane tickets and last minute offers. Also check out MCO-SDQ flight schedule to find best flight time, convenient departure and arrival airports.

Flight Information

Below we will explain in detail what the flights cost on the destination from Orlando to Santo Domingo depends on and how to choose the most interesting flight option for you.

Distance between Orlando and Santo Domingo is 1625 miles. Time difference between the cities is 1h. Airplanes depart 05:30 to 21:00 from 3 Orlando airports and arrive 05:30 to 21:00 to 3 Santo Domingo airports. Average flight time is 41h 50m.

  • The fastest flight 22h 5m
  • Average flight time 41h 50m
  • The earliest flight 05:30
  • The latest flight 21:00
  • Distance 1010 ml

The cheapest months to travel to Santo Domingo are july (from 384 $), september (from 403 $), august (from 487 $).

What is the lowest airfare Orlando to Santo Domingo?

The cheapest plane ticket found by our users is $384. This airfare is for economy class on one-way NK2196 flight by Spirit Airlines for July 5, 2025 which leaves Orlando Int. in Orlando at 08:25 am and arrives at Santo Domingo La Isabela Int at 13:30.

Economy class
$384
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Business class
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First class
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Flight Schedule Orlando (Florida) to Santo Domingo

05:30 — 13:30+1day
32h flight time
Find flight
from$403
05:30 — 06:35 Orlando — Miami
NK195 Spirit Airlines
7h 2m stop
13:37 — 16:34 Miami — Aruba
NK885 Spirit Airlines
19h 56m stop
12:30 — 13:30 Aruba — Santo Domingo
W1844 W1
08:25 — 13:30+1day
29h 5m flight time
Find flight
from$384
08:25 — 09:37 Orlando — Miami
NK2196 Spirit Airlines
2h 13m stop
11:50 — 14:40 Miami — Aruba
NK885 Spirit Airlines
21h 50m stop
12:30 — 13:30 Aruba — Santo Domingo
W1844 W1
09:00 — 11:00+2days
50h flight time
Find flight
from$622
09:00 — 11:57 Orlando — Bogota
NK1921 Spirit Airlines
19h 8m stop
07:05 — 09:55 Bogota — Willemstad
AV92 Avianca
24h 5m stop
10:00 — 11:00 Willemstad — Santo Domingo
Y2152 Y2
09:01 — 13:30+1day
28h 29m flight time
Find flight
from$663
09:01 — 11:59 Orlando — Bogota
NK1921 Spirit Airlines
19h 1m stop
07:00 — 09:50 Bogota — Aruba
AV242 Avianca
2h 40m stop
12:30 — 13:30 Aruba — Santo Domingo
W1844 W1
09:05 — 15:30+2days
54h 25m flight time
Find flight
from$542
09:05 — 12:00 Orlando — Bogota
NK1921 Spirit Airlines
23h 49m stop
11:49 — 14:45 Bogota — Aruba
P57002 Copa Airlines Colombia
23h 45m stop
14:30 — 15:30 Aruba — Santo Domingo
Y2172 Y2
11:00 — 14:30+2days
51h 30m flight time
Find flight
from$519
11:00 — 13:55 Orlando — Toronto
WS1227 WestJet
18h 35m stop
08:30 — 13:15 Toronto — Saint Martin
WS2276 WestJet
24h 15m stop
13:30 — 14:30 Saint Martin — Santo Domingo
Y2162 Y2
15:15 — 14:30+1day
23h 15m flight time
Find flight
from$688
15:15 — 18:14 Orlando — Bogota
AV29 Avianca
12h 51m stop
07:05 — 09:55 Bogota — Willemstad
AV92 Avianca
3h 35m stop
13:30 — 14:30 Willemstad — Santo Domingo
Y2152 Y2
15:15 — 11:00+2days
43h 45m flight time
Find flight
from$821
15:15 — 18:14 Orlando — Bogota
AV29 Avianca
12h 51m stop
07:05 — 09:55 Bogota — Willemstad
AV92 Avianca
24h 5m stop
10:00 — 11:00 Willemstad — Santo Domingo
Y2154 Y2
16:25 — 14:30+1day
22h 5m flight time
Find flight
from$707
16:25 — 19:25 Orlando — Bogota
AV219 Avianca
11h 40m stop
07:05 — 09:55 Bogota — Willemstad
AV92 Avianca
3h 35m stop
13:30 — 14:30 Willemstad — Santo Domingo
Y2152 Y2
16:25 — 11:00+2days
42h 35m flight time
Find flight
from$878
16:25 — 19:25 Orlando — Bogota
AV219 Avianca
11h 40m stop
07:05 — 09:55 Bogota — Willemstad
AV92 Avianca
24h 5m stop
10:00 — 11:00 Willemstad — Santo Domingo
Y2154 Y2
17:05 — 11:00+2days
41h 55m flight time
Find flight
from$889
17:05 — 20:10 Orlando — Bogota
LA4407 LAN Airlines
10h 55m stop
07:05 — 09:55 Bogota — Willemstad
AV92 Avianca
24h 5m stop
10:00 — 11:00 Willemstad — Santo Domingo
Y2154 Y2
19:40 — 11:00+2days
39h 20m flight time
Find flight
from$487
19:40 — 20:53 Orlando — Miami
NK675 Spirit Airlines
11h 47m stop
08:40 — 11:35 Miami — Willemstad
AD8787 Azul
22h 25m stop
10:00 — 11:00 Willemstad — Santo Domingo
Y2152 Y2
20:45 — 14:30+2days
41h 45m flight time
Find flight
from$464
20:45 — 23:47 Orlando — Toronto
PD506 Porter Airlines
8h 43m stop
08:30 — 13:15 Toronto — Saint Martin
WS2276 WestJet
24h 16m stop
13:30 — 14:30 Saint Martin — Santo Domingo
Y2162 Y2
21:00 — 15:30+2days
42h 30m flight time
Find flight
from$680
21:00 — 23:59 Orlando — Toronto
WS1167 WestJet
8h 46m stop
08:45 — 13:55 Toronto — Aruba
WS2198 WestJet
24h 35m stop
14:30 — 15:30 Aruba — Santo Domingo
Y2172 Y2
Full flight schedule will help you in detecting at what time planes fly from Orlando to Santo Domingo. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
*Departure and arrival times - local. Updated on October 16, 2025.

Popular Airlines on the Route

The flight Orlando — Santo Domingo is served by 5 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Porter Airlines - 1 departures per week at the price of from $ 464 . And the most expensive tickets are offered by LAN Airlines airline - from $ 889.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 14 flights with layovers on the route. The fastest connecting flight is AV219 by Avianca takes 22h 5m and the cheapest is NK2196 by Spirit Airlines for $384.

  • PD - Porter Airlines
    from $464
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  • AV - Avianca
    from $688
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  • LA - LAN Airlines
    from $889
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  • WS - WestJet
    from $519
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  • NK - Spirit Airlines
    from $384
    Find
See more connecting flights

Airports

You can fly from Orlando to Santo Domingo from 3 airports (Orlando Int., Herndon, Walt Disney World).

Orlando airports

  • Orlando Int.-MCO
    from $384
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  • Herndon-ORL
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  • Walt Disney World-DWS
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Santo Domingo airports

  • La Isabela Int-JBQ
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  • Las Americas-SDQ
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  • Santo Domingo Herrera-HEX
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How to book a plane ticket yourself?

How to book an air ticket yourself?
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  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

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