Cheap Flights from Orlando, FL to Santo Domingo from $424

Return flight: Santo Domingo – Orlando
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On Cheapflightsplus.com you will find 12 connecting flights from Orlando to Santo Domingo. You can compare airfare deals from 5 airlines and multiple travel sites from $424, book and save on cheap plane tickets and last minute offers. Also check out MCO-SDQ flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Orlando to Santo Domingo Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $424 (one-way), $727 (round-trip).
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Best Flights from Orlando to Santo Domingo Today

Take a look at the list of non stop flights and flights with layovers from Orlando to Santo Domingo with the lowest price of $424. Take a look at the list of flights with layovers from Orlando to Santo Domingo from $424. There’re no direct flights. The fastest connecting flight – 22h 5m.
Price Departure Arrival Flight Duration Airline Flight
from $424
Find flight
05:30
Orlando
Orlando Int.
 13:30+1 день
Santo Domingo
La Isabela Int
 32h 0m
layover
7h 2m - Miami
19h 56m - Aruba
 Spirit Airlines
NK195
NK885
W1844
from $488
Find flight
20:45
Orlando
Orlando Int.
 14:30+2 дня
Santo Domingo
La Isabela Int
 41h 45m
layover
8h 43m - Toronto
24h 16m - Saint Martin
 Porter Airlines
PD506
WS2276
Y2162
from $512
Find flight
19:40
Orlando
Orlando Int.
 11:00+2 дня
Santo Domingo
La Isabela Int
 39h 20m
layover
11h 47m - Miami
22h 25m - Willemstad
 Spirit Airlines
NK675
AD8787
Y2152
from $546
Find flight
11:00
Orlando
Orlando Int.
 14:30+2 дня
Santo Domingo
La Isabela Int
 51h 30m
layover
18h 35m - Toronto
24h 15m - Saint Martin
 WestJet
WS1227
WS2276
Y2162
from $570
Find flight
09:05
Orlando
Orlando Int.
 15:30+2 дня
Santo Domingo
La Isabela Int
 54h 25m
layover
23h 49m - Bogota
23h 45m - Aruba
 Spirit Airlines
NK1921
P57002
Y2172
from $654
Find flight
09:00
Orlando
Orlando Int.
 11:00+2 дня
Santo Domingo
La Isabela Int
 50h 0m
layover
19h 8m - Bogota
24h 5m - Willemstad
 Spirit Airlines
NK1921
AV92
Y2152
from $715
Find flight
21:00
Orlando
Orlando Int.
 15:30+2 дня
Santo Domingo
La Isabela Int
 42h 30m
layover
8h 46m - Toronto
24h 35m - Aruba
 WestJet
WS1167
WS2198
Y2172
from $724
Find flight
15:15
Orlando
Orlando Int.
 14:30+1 день
Santo Domingo
La Isabela Int
 23h 15m
layover
12h 51m - Bogota
3h 35m - Willemstad
 Avianca
AV29
AV92
Y2152
from $743
Find flight
16:25
Orlando
Orlando Int.
 14:30+1 день
Santo Domingo
La Isabela Int
 22h 5m
layover
11h 40m - Bogota
3h 35m - Willemstad
 Avianca
AV219
AV92
Y2152
from $864
Find flight
15:15
Orlando
Orlando Int.
 11:00+2 дня
Santo Domingo
La Isabela Int
 43h 45m
layover
12h 51m - Bogota
24h 5m - Willemstad
 Avianca
AV29
AV92
Y2154
from $924
Find flight
16:25
Orlando
Orlando Int.
 11:00+2 дня
Santo Domingo
La Isabela Int
 42h 35m
layover
11h 40m - Bogota
24h 5m - Willemstad
 Avianca
AV219
AV92
Y2154
from $935
Find flight
17:05
Orlando
Orlando Int.
 11:00+2 дня
Santo Domingo
La Isabela Int
 41h 55m
layover
10h 55m - Bogota
24h 5m - Willemstad
 LAN Airlines
LA4407
AV92
Y2154
Show all tickets
*Departure and arrival times - local. Prices indicated for one-way flights. Information updated on July 12, 2025
Full flight schedule will help you in detecting at what time planes fly from Orlando to Santo Domingo. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
05:30 — 13:30
+1 day
05:30 — 06:35 NK195 Spirit Airlines
Orlando — Miami
7h 2m stop
13:37 — 16:34 NK885 Spirit Airlines
Miami — Aruba
19h 56m stop
12:30 — 13:30 W1844 W1
Aruba — Santo Domingo
32h
including layover
Find flight
from$424
09:00 — 11:00
+2 days
09:00 — 11:57 NK1921 Spirit Airlines
Orlando — Bogota
19h 8m stop
07:05 — 09:55 AV92 Avianca
Bogota — Willemstad
24h 5m stop
10:00 — 11:00 Y2152 Y2
Willemstad — Santo Domingo
50h
including layover
Find flight
from$654
09:05 — 15:30
+2 days
09:05 — 12:00 NK1921 Spirit Airlines
Orlando — Bogota
23h 49m stop
11:49 — 14:45 P57002 Copa Airlines Colombia
Bogota — Aruba
23h 45m stop
14:30 — 15:30 Y2172 Y2
Aruba — Santo Domingo
54h 25m
including layover
Find flight
from$570
11:00 — 14:30
+2 days
11:00 — 13:55 WS1227 WestJet
Orlando — Toronto
18h 35m stop
08:30 — 13:15 WS2276 WestJet
Toronto — Saint Martin
24h 15m stop
13:30 — 14:30 Y2162 Y2
Saint Martin — Santo Domingo
51h 30m
including layover
Find flight
from$546
15:15 — 14:30
+1 day
15:15 — 18:14 AV29 Avianca
Orlando — Bogota
12h 51m stop
07:05 — 09:55 AV92 Avianca
Bogota — Willemstad
3h 35m stop
13:30 — 14:30 Y2152 Y2
Willemstad — Santo Domingo
23h 15m
including layover
Find flight
from$724
15:15 — 11:00
+2 days
15:15 — 18:14 AV29 Avianca
Orlando — Bogota
12h 51m stop
07:05 — 09:55 AV92 Avianca
Bogota — Willemstad
24h 5m stop
10:00 — 11:00 Y2154 Y2
Willemstad — Santo Domingo
43h 45m
including layover
Find flight
from$864
16:25 — 14:30
+1 day
16:25 — 19:25 AV219 Avianca
Orlando — Bogota
11h 40m stop
07:05 — 09:55 AV92 Avianca
Bogota — Willemstad
3h 35m stop
13:30 — 14:30 Y2152 Y2
Willemstad — Santo Domingo
22h 5m
including layover
Find flight
from$743
16:25 — 11:00
+2 days
16:25 — 19:25 AV219 Avianca
Orlando — Bogota
11h 40m stop
07:05 — 09:55 AV92 Avianca
Bogota — Willemstad
24h 5m stop
10:00 — 11:00 Y2154 Y2
Willemstad — Santo Domingo
42h 35m
including layover
Find flight
from$924
17:05 — 11:00
+2 days
17:05 — 20:10 LA4407 LAN Airlines
Orlando — Bogota
10h 55m stop
07:05 — 09:55 AV92 Avianca
Bogota — Willemstad
24h 5m stop
10:00 — 11:00 Y2154 Y2
Willemstad — Santo Domingo
41h 55m
including layover
Find flight
from$935
19:40 — 11:00
+2 days
19:40 — 20:53 NK675 Spirit Airlines
Orlando — Miami
11h 47m stop
08:40 — 11:35 AD8787 Azul
Miami — Willemstad
22h 25m stop
10:00 — 11:00 Y2152 Y2
Willemstad — Santo Domingo
39h 20m
including layover
Find flight
from$512
20:45 — 14:30
+2 days
20:45 — 23:47 PD506 Porter Airlines
Orlando — Toronto
8h 43m stop
08:30 — 13:15 WS2276 WestJet
Toronto — Saint Martin
24h 16m stop
13:30 — 14:30 Y2162 Y2
Saint Martin — Santo Domingo
41h 45m
including layover
Find flight
from$488
21:00 — 15:30
+2 days
21:00 — 23:59 WS1167 WestJet
Orlando — Toronto
8h 46m stop
08:45 — 13:55 WS2198 WestJet
Toronto — Aruba
24h 35m stop
14:30 — 15:30 Y2172 Y2
Aruba — Santo Domingo
42h 30m
including layover
Find flight
from$715
*Departure and arrival times - local. Updated on July 12, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Orlando to Santo Domingo depends on and how to choose the most interesting flight option for you.

Distance between Orlando and Santo Domingo is 1625 miles. Time difference between the cities is 1h. Airplanes depart 05:30 to 21:00 from 3 Orlando airports and arrive 05:30 to 21:00 to 3 Santo Domingo airports. Average flight time is 42h 13m.

  • The fastest flight 22h 5m
  • Average flight time 42h 13m
  • The earliest flight 05:30
  • The latest flight 21:00
  • Distance 1010 ml

The cheapest months to travel to Santo Domingo are september (from 424 $), august (from 512 $), july (from 570 $).

What is the lowest airfare Orlando to Santo Domingo?

The cheapest plane ticket found by our users is $424. This airfare is for economy class on one-way NK195 flight by Spirit Airlines for September 27, 2025 which leaves Orlando Int. in Orlando at 05:30 am and arrives at Santo Domingo La Isabela Int at 13:30.

Economy class
$424
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Business class
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First class
?
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Popular Airlines on the Route

The flight Orlando — Santo Domingo is served by 5 regular airlines and 3 low-cost airlines. Most of the flights on this route are operated by Porter Airlines - 1 departures per week at the price of from $ 488 . And the most expensive tickets are offered by LAN Airlines airline - from $ 935.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 12 flights with layovers on the route. The fastest connecting flight is AV219 by Avianca takes 22h 5m and the cheapest is NK195 by Spirit Airlines for $424.

  • PD - Porter Airlines
    from $488
    Find
  • AV - Avianca
    from $724
    Find
  • LA - LAN Airlines
    from $935
    Find
  • WS - WestJet
    from $546
    Find
  • NK - Spirit Airlines
    from $424
    Find
See more connecting flights

Airports

You can fly from Orlando to Santo Domingo from 3 airports (Orlando Int., Herndon, Walt Disney World).

Orlando airports

  • Orlando Int.-MCO
    from $424
    Find
  • Herndon-ORL
    Find
  • Walt Disney World-DWS
    Find

Santo Domingo airports

  • La Isabela Int-JBQ
    Find
  • Las Americas-SDQ
    Find
  • Santo Domingo Herrera-HEX
    Find

Airplanes

There are flights to Santo Domingo from Orlando by 5 airlines that use 0 aircraft brands. They range from huge modern airplanes to small-sized.

Top Domestic Destinations from Orlando

You may also consider searching for discounted plane tickets to some other popular places from Orlando within United States.

Top International Destinations from Orlando

Our state-of-the art metasearch will definitely provide you with the best airfare on international flights. We’re proud to partner with many reliable travel suppliers located outside the US what gives us an opportunity to offer the most competitive prices on far destinations.

How to book a plane ticket yourself?

How to book an air ticket yourself?
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  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

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