Cheap Flights from Madrid to San Francisco, CA from $376

On Cheapflightsplus.com you will find 96 connecting flights from Madrid to San Francisco. You can compare airfare deals from 14 airlines and multiple travel sites from $376, book and save on cheap plane tickets and last minute offers. Also check out MAD-SFO flight schedule to find best flight time, convenient departure and arrival airports.

Find One-Way and Round-Trip Madrid to San Francisco Flight Deals

To find the cheapest one way airline ticket select the date with the lowest price on the calendar below and click «Find Flights». To search for round-trip flight deals click on the link «Check prices for return flights» and select the date of the return flight. Cheapest flights in November: $376 (one-way), $645 (round-trip).
Direct flights
  • Check to choose departure date Check to choose departure date
Check prices for return flight
Find flights
Full flight schedule will help you in detecting at what time planes fly from Madrid to San Francisco. You can also specify the concrete flights and airlines on the route and how long the flight actually is. Use the calendar for today, tomorrow or other specific date as some flights are available only on certain days of the week.
Departure Arrival Flight Details Flight Duration Price
01:30 — 22:45
00:35 — 05:00 AV47 Avianca
Madrid — Bogota
9h 20m stop
14:15 — 16:25 AV382 Avianca
Bogota — San Salvador
1h 20m stop
17:35 — 21:55 AV560 Avianca
San Salvador — San Francisco
30h 15m
including layover
Find flight
from$651
07:00 — 13:50
07:00 — 08:25 IB711 Iberia
Madrid — London
2h 20m stop
10:45 — 13:50 IB3626 Iberia
London — San Francisco
15h 50m
including layover
Find flight
from$444
08:00 — 20:50
08:00 — 09:55 UX1027 Air Europa
Madrid — Paris
8h 35m stop
18:30 — 20:50 BF710 Bluebird Cargo
Paris — San Francisco
21h 50m
including layover
Find flight
from$645
09:40 — 22:45
08:30 — 12:55 AV27 Avianca
Madrid — Bogota
1h 10m stop
14:15 — 16:25 AV382 Avianca
Bogota — San Salvador
1h 20m stop
17:35 — 21:55 AV560 Avianca
San Salvador — San Francisco
22h 5m
including layover
Find flight
from$651
10:15 — 10:25
+1 day
10:15 — 11:35 U28020 EasyJet
Madrid — London
2h 25m stop
14:00 — 18:25 Z0783 Z0
London — Orlando
13h 15m stop
07:40 — 10:25 F91645 Frontier Airlines
Orlando — San Francisco
33h 10m
including layover
Find flight
from$618
14:20 — 20:50
14:20 — 16:15 UX1029 Air Europa
Madrid — Paris
2h 15m stop
18:30 — 20:50 BF710 Bluebird Cargo
Paris — San Francisco
15h 30m
including layover
Find flight
from$590
14:20 — 20:50
14:20 — 16:15 UX1029 Air Europa
Madrid — Paris
2h 15m stop
18:30 — 20:50 TX6710 Air Caraibes
Paris — San Francisco
15h 30m
including layover
Find flight
from$608
14:30 — 20:50
14:30 — 16:30 IB577 Iberia
Madrid — Paris
2h stop
18:30 — 20:50 BF710 Bluebird Cargo
Paris — San Francisco
15h 20m
including layover
Find flight
from$571
17:30 — 23:55
+1 day
17:30 — 20:59 AV11 Avianca
Madrid — Bogota
10h 16m stop
07:15 — 09:15 AV70 Avianca
Bogota — San Salvador
9h 25m stop
18:40 — 23:55 AV558 Avianca
San Salvador — San Francisco
39h 25m
including layover
Find flight
from$641
20:10 — 13:50
+1 day
20:10 — 20:35 TP1019 TAP Portugal
Madrid — Lisbon
9h 30m stop
05:55 — 09:30 TP428 TAP Portugal
Lisbon — Paris
2h stop
11:30 — 13:50 BF714 Bluebird Cargo
Paris — San Francisco
26h 40m
including layover
Find flight
from$635
20:10 — 13:50
+1 day
20:10 — 20:35 TP1019 TAP Portugal
Madrid — Lisbon
9h 30m stop
05:55 — 09:30 TP428 TAP Portugal
Lisbon — Paris
2h stop
11:30 — 13:50 TX6714 Air Caraibes
Paris — San Francisco
26h 40m
including layover
Find flight
from$635
20:40 — 13:50
+1 day
20:40 — 23:10 W46014 Aero Services Executive
Madrid — Rome
7h 5m stop
06:15 — 08:30 W46061 Aero Services Executive
Rome — Paris
3h stop
11:30 — 13:50 BF714 Bluebird Cargo
Paris — San Francisco
26h 10m
including layover
Find flight
from$512
21:45 — 13:50
+1 day
21:45 — 23:50 IB591 Iberia
Madrid — Paris
11h 40m stop
11:30 — 13:50 TX6714 Air Caraibes
Paris — San Francisco
25h 5m
including layover
Find flight
from$615
22:15 — 13:50
+1 day
22:15 — 22:40 TP1021 TAP Portugal
Madrid — Lisbon
7h 25m stop
05:55 — 09:30 TP428 TAP Portugal
Lisbon — Paris
2h stop
11:30 — 13:50 TX6714 Air Caraibes
Paris — San Francisco
24h 35m
including layover
Find flight
from$597
22:15 — 13:50
+1 day
22:15 — 22:40 TP1021 TAP Portugal
Madrid — Lisbon
7h 25m stop
05:55 — 09:30 TP428 TAP Portugal
Lisbon — Paris
2h stop
11:30 — 13:50 BF714 Bluebird Cargo
Paris — San Francisco
24h 35m
including layover
Find flight
from$597
*Departure and arrival times - local. Updated on September 14, 2025

Flight Information

Below we will explain in detail what the flights cost on the destination from Madrid to San Francisco depends on and how to choose the most interesting flight option for you.

Distance between Madrid and San Francisco is 9330 miles. Time difference between the cities is 9h. Airplanes depart 01:30 to 23:10 from 2 Madrid airports and arrive 01:30 to 23:10 to 3 San Francisco airports. Average flight time is 23h 56m.

  • The fastest flight 14h 45m
  • Average flight time 23h 56m
  • The earliest flight 01:30
  • The latest flight 23:10
  • Distance 5798 ml

Popular Airlines on the Route

The flight Madrid — San Francisco is served by 14 regular airlines and 2 low-cost airlines. Most of the flights on this route are operated by KLM - 1 departures per week at the price of from $ 674 . And the most expensive tickets are offered by Iberia airline - from $ 1164.

Direct flights

There’re no direct flights on this route. Try flights with stops.

Connecting Flights

There are 96 flights with layovers on the route. The fastest connecting flight is KL1500 by KLM takes 14h 45m.

  • KL - KLM
    from $674
    Find
  • UX - Air Europa
    from $590
    Find
  • EI - Aer Lingus
    from $920
    Find
  • AF - Air France
    from $695
    Find
  • UA - United Airlines
    from $1094
    Find
  • AV - Avianca
    from $641
    Find
  • TK - Turkish Airlines
    from $665
    Find
  • IB - Iberia
    from $444
    Find
  • TO - Transavia France
    from $843
    Find
  • TP - TAP Portugal
    from $597
    Find
  • LH - Lufthansa
    from $856
    Find
  • W4 - Aero Services Executive
    from $512
    Find
See more connecting flights

Airports

You can fly from Madrid to San Francisco from 2 airports (Barajas, Torrejon).

Madrid airports

  • Barajas-MAD
    from $444
    Find
  • Torrejon-TOJ
    Find

San Francisco airports

  • San Francisco-SFO
    Find
  • Embarkadero-EMB
    Find
  • China Basin Heliport-JCC
    Find

How to book a plane ticket yourself?

How to book an air ticket yourself?
  • Fill in the search parameters — cities of departure and destination, departure and return dates and click «Find flights»
  • Select the best flight that you like. Please, check the airports of departure and arrival. Select the best fare, but pay attention to the following flight details - airports of departure and arrival, flight duration and layovers. Please use filters and sort to find the best flight.
  • Click «Buy» when you are ready — our system will redirect you to the site that sells the selected flight ticket.
  • Fill in all passenger and payment information — passport and contact information, please double check all passengers’ names and make a payment for your itinerary.
  • That's it — you will receive an email with your e-ticket usually within 10 minutes after your flight is confirmed. Please, print the e-ticket and have it with you at the airport. You would need to have only a passport and/or a required form of ID to travel. Please, check your Visa requirements if you travel outside of the United States or Canada.

    To find a plane ticket, please select dates.

Back